Abstract:
OBJECTIVES:To evaluate tomosynthesis compared with 2D-mammography in cancer detection and recalls in a screening-programme, and assess performing synthesized instead of 2D, and compare double reading of 2D with single reading of tomosynthesis. METHODS:Women (age 50-69 years) participating in the screening-programme were included. 2D-mammography and tomosynthesis were performed. There were four reading models: 2D-mammography (first); 2D-mammography (second); tomosynthesis + synthesized (third); tomosynthesis + synthesized + 2D (fourth reading). Paired double reading of 2D (first+second) and tomosynthesis (third+fourth) were analysed. RESULTS:In 16,067 participants, there were 98 cancers and 1,196 recalls. Comparing double reading of 2D with single reading of tomosynthesis, there was an increase of 12.6 % in cancer detection with the third reading (p= 0.043) and 6.9 % with the fourth reading (p=0.210), and a decrease in recalls of 40.5 % (p<0.001) and 44.4 % (p<0.001), respectively. With double reading of both techniques, there was an increase in cancer detection of 17.4 % (p = 0.004) and a decrease in recalls of 12.5 % (p = 0.001) with tomosynthesis. CONCLUSION:Single reading of tomosynthesis plus synthesized increased cancer detection and decreased recalls compared with double reading 2D. 2D did not improve results when added to tomosynthesis. KEY POINTS:• Tomosynthesis increases cancer detection and decreases recall rates versus 2D mammography. • Synthesized-mammography avoids performing 2D, showing higher cancer detection. • Single reading of tomosynthesis + synthesized is feasible as a new practice.
journal_name
Eur Radioljournal_title
European radiologyauthors
Romero Martín S,Raya Povedano JL,Cara García M,Santos Romero AL,Pedrosa Garriguet M,Álvarez Benito Mdoi
10.1007/s00330-017-5219-8subject
Has Abstractpub_date
2018-06-01 00:00:00pages
2484-2491issue
6eissn
0938-7994issn
1432-1084pii
10.1007/s00330-017-5219-8journal_volume
28pub_type
杂志文章abstract:OBJECTIVES:To develop an MRI enterography global score (MEGS) of Crohn's disease (CD) activity compared with a reference standard of faecal calprotectin (fC), C-reactive protein (CRP) and Harvey-Bradshaw index (HBI). METHODS:Calprotectin, CRP and HBI were prospectively recorded for 71 patients (median age 33, male 35)...
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