Abstract:
OBJECTIVE:This study aims to investigate whether aneurysm wall enhancement (AWE) is independently associated with symptomatic status of unruptured intracranial aneurysms (UIAs). METHODS:One hundred thirty-nine consecutive patients (67 male, mean age 58 ± 11 years) with 79 symptomatic and 87 asymptomatic UIAs were imaged using black-blood MRI pre- and post-gadolinium contrast administration and 3D DSA. Symptoms related to aneurysms were identified including cranial nerve deficits and headache. AWE grade and area were characterized, and aneurysm size was measured on DSA. Multivariate binary logistic regression analysis was used to identify factors associated with symptoms. Further subgroup analysis was performed for aneurysms size < 10 mm. RESULTS:Symptomatic UIAs had significantly larger aneurysm size (11.2 ± 6.2 mm vs. 6.4 ± 3.3 mm), enhancement grade (1.3 ± 0.6 vs. 0.4 ± 0.6), enhancement area (2.0 ± 0.9 vs. 0.4 ± 0.7), and higher prevalence of thick enhancement (39% vs. 3%) compared with asymptomatic UIAs, all p < 0.001. In multivariate analysis, only AWE area (odds ratio [OR] 6.9, 95% confidence interval [4.0, 11.7]) was independently associated with symptoms. AWE area had an area under curve (AUC) value of 0.888, with 72.2% sensitivity and 92.0% specificity for symptoms, which was superior to aneurysm size (AUC of 0.771, with 75.9% sensitivity and 65.5% specificity). In the subgroup analysis of aneurysms smaller than 10 mm (n = 118), AWE area (OR, 7.0, p < 0.001) remained the only independent risk factor associated with symptoms. CONCLUSIONS:Larger AWE area is independently associated with symptomatic UIAs, which may provide additional value to guide UIA management and improve patient outcomes. KEY POINTS:• Symptomatic intracranial aneurysms are larger and more often demonstrate significant wall enhancement than asymptomatic aneurysms. • Larger wall enhancement area is independently associated with symptomatic intracranial aneurysm.
journal_name
Eur Radioljournal_title
European radiologyauthors
Zhu C,Wang X,Eisenmenger L,Shi Z,Degnan A,Tian B,Liu Q,Hess C,Saloner D,Lu Jdoi
10.1007/s00330-020-07063-6subject
Has Abstractpub_date
2020-12-01 00:00:00pages
6413-6420issue
12eissn
0938-7994issn
1432-1084pii
10.1007/s00330-020-07063-6journal_volume
30pub_type
杂志文章abstract:OBJECTIVES:To assess the combined role of tumor vascularity, estimated from perfusion MRI, and MGMT methylation status on overall survival (OS) in patients with glioblastoma. METHODS:A multicentric international dataset including 96 patients from NCT03439332 clinical study were used to study the prognostic relationshi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07297-4
更新日期:2020-10-01 00:00:00
abstract::An orthopedic surgeon had been condemned for different offences to 2 years and 6 months imprisonment by the superior court in Frankfurt/Main. One point of the ruling had been the use of X-rays without medical indication, which the superior court of Frankfurt/Main finally did not assess as bodily harm. The supreme cour...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050748
更新日期:1999-01-01 00:00:00
abstract::This technical note describes the use of dynamic MRI in the diagnosis of groin herniations. A review of the anatomy of the groin is presented and 4 representative cases are described. This paper indicates that dynamic MRI can be used to confirm the diagnosis in patients with clinically evident groin herniations. ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050377
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:Diffusion-weighted MR imaging has shown diagnostic value for differential diagnosis of breast lesions. Diffusion tensor imaging (DTI) adds information about tissue microstructure by addressing diffusion direction. We have examined the diagnostic application of DTI of the breast. METHODS:A total of 59 patien...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1901-9
更新日期:2011-01-01 00:00:00
abstract::The aim of this study was to assess whether magnetic resonance imaging could predict the outcome of attempted vaginal delivery in a group of pregnant women whose parturition had to be induced by oxytocin. The signal intensity and morphology alterations in the cervix of 21 full-term pregnant women were analyzed before ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300051001
更新日期:2000-01-01 00:00:00
abstract::The aim of this study was to evaluate the radiation dose given by semicoronal CT of the sacroiliac joints (SIJs) in comparison with axial CT and conventional radiography. The total effective radiation doses given by serial contiguous semicoronal and axial CT, using 5-mm slices, 120 kV and 330 mAs, were determined by m...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-001-1297-7
更新日期:2002-11-01 00:00:00
abstract::Hepatobiliary contrast agents with uptake into hepatocytes followed by variable biliary excretion represent a unique class of cell-specific MR contrast agents. Two hepatobiliary contrast agents, mangafodipir trisodium and gadobenate dimeglumine, are already clinically approved. A third hepatobiliary contrast agent, Gd...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-004-2236-1
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVES:To compare the value of functional future liver remnant (functFLR) to established clinical and imaging variables in prediction of post-hepatectomy liver failure (PHLF) after major liver resection. METHODS:This retrospective, cross-sectional study included 62 patients, who underwent gadoxetic acid enhanced M...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5487-y
更新日期:2018-11-01 00:00:00
abstract::New technologies are needed to characterize the migration and survival of antigen-specific T cells in vivo. In this study, we developed a novel technique for the labeling of human cytotoxic T lymphocytes with superparamagnetic iron-oxide particles and the subsequent depiction with a conventional 1.5-T magnetic resonan...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-0874-4
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:To evaluate the effectiveness of bag-of-features (BOF)-based radiomics for differentiating ocular adnexal lymphoma (OAL) and idiopathic orbital inflammation (IOI) from contrast-enhanced MRI (CE-MRI). METHODS:Fifty-six patients with pathologically confirmed IOI (28 patients) and OAL (28 patients) were random...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07110-2
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:This study aims to establish and validate a radiomics nomogram based on contrast-enhanced spectral mammography (CESM) for prediction of axillary lymph node (ALN) metastasis in breast cancer. METHODS:This retrospective study included 394 patients with breast cancer who underwent CESM examination in two hospit...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07016-z
更新日期:2020-12-01 00:00:00
abstract::To evaluate long-term effects of arterial embolization (AE) for postpartum hemorrhage (PPH) on menses recovery and subsequent pregnancies. One hundred thirteen consecutive patients, recruited from 1999 to 2006, who had undergone AE for severe PPH were evaluated in a retrospective monocentric study. As embolization age...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1140-5
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:To evaluate complex CSF movements and shear stress in patients with idiopathic normal pressure hydrocephalus (iNPH) on four-dimensional (4D) flow MRI. METHODS:Three-dimensional velocities and volumes of the reciprocating CSF movements through 12 ROIs from the foramen of Monro to the upper cervical spine wer...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-06825-6
更新日期:2020-08-01 00:00:00
abstract::The purpose of this study was to first evaluate Levovist (Schering, Berlin, Germany), an echo-contrast agent, during power Doppler sonography (PDS) in patients with synovitis using asymptomatic joints as controls. Then we evaluated the accuracy of this technique against contrast-enhanced MRI. Forty patients (19 men an...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s003300000650
更新日期:2001-01-01 00:00:00
abstract::The aim of this study was to depict and characterize inflammatory soft tissue proliferations caused by rheumatoid arthritis (RA) in the craniocervical region by unenhanced and contrast-enhanced CT. Computed tomography of the craniocervical region was performed in 35 patients in the axial plane before and after the i.v...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000433
更新日期:2000-01-01 00:00:00
abstract::Inflammatory myofibroblastic tumour (IMFT) is a distinct entity under the group of inflammatory pseudotumours. Sometimes these pseudotumours can have an aggressive appearance on imaging, which makes it indistinguishable from other malignant neoplasms. We present a case of IMFT of the bladder in a child. ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1646-5
更新日期:2010-08-01 00:00:00
abstract::A recent development in biomedical imaging is the non-invasive mapping of molecular events in intact tissues using fluorescence. Underpinning to this development is the discovery of bio-compatible, specific fluorescent probes and proteins and the development of highly sensitive imaging technologies for in vivo fluores...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-002-1524-x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:High radiation dose during CT perfusion (CTp) studies contributes to prevent CTp application in daily clinical practice. This work evaluates the consequences of scan delay on perfusion parameters and provides guidelines to help reducing the radiation dose by choosing the most appropriate delay. METHODS:Fift...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-019-06259-9
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:Osteoporosis is a prevalent and treatable condition, but it remains underdiagnosed. In this study, a deep learning-based system was developed to automatically measure bone mineral density (BMD) for opportunistic osteoporosis screening using low-dose chest computed tomography (LDCT) scans obtained for lung can...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-06679-y
更新日期:2020-07-01 00:00:00
abstract::Typical MRI findings for gastro-intestinal stromal tumours (GIST) under treatment with imatinib were evaluated. MRI was performed in 45 patients (25 responders, 20 non-responders) with metastatic or locally advanced, unresectable GIST. Target lesions were selected and re-evaluated after 2, 4, and 6 months of therapy w...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-005-2867-x
更新日期:2005-12-01 00:00:00
abstract::The purpose of this study was to determine the feasibility of using virtual bronchoscopy simulations to depict stenoses of the tracheobronchial tree. Virtual bronchoscopy simulations, based on ray casting, were applied to spiral-CT data sets of 29 patients presenting 41 stenoses of the central airways, proved with fib...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050218
更新日期:1997-01-01 00:00:00
abstract::We report a case of renal cell carcinoma with solitary metachronous contralateral adrenal metastasis occurring 23 years after radical nephrectomy. The patient was treated with adrenalectomy. He is alive with no evidence of disease 1 year postoperatively. Solitary metachronous contralateral adrenal metastases from rena...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050204
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:Our two-centre prospective study evaluates the usefulness of 64-slice coronary computed tomography (CCT) to rule out significant coronary artery stenosis in patients admitted in emergency departments (ED) for acute coronary syndromes (ACS) with low-to-intermediate risk score. METHODS:Patients (175) admitted ...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-011-2354-5
更新日期:2012-05-01 00:00:00
abstract::The purpose was to provide a diffusion-weighted whole-body magnetic resonance (MR) imaging sequence with background body signal suppression (DWIBS) at 3.0 Tesla. A diffusion-weighted spin-echo echo-planar imaging sequence was combined with the following methods of fat suppression: short TI inversion recovery (STIR), s...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0717-8
更新日期:2007-12-01 00:00:00
abstract::We report a case of a large renal tumour containing small amounts of fat and some calcification that proved to be a renal cell carcinoma. The CT appearance of the tumour was suggestive of an angiomyolipoma. Although the overwhelming majority of renal masses containing fat are angiomyolipomas, in the presence of calcif...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050367
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:To investigate the impact of an adaptive statistical iterative reconstruction (ASiR) algorithm on diagnostic accuracy and confidence for the diagnosis of hypervascular liver tumours, as well as the reader's perception of image quality, using a low tube voltage (80 kVp), high tube current computed tomography ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-2964-1
更新日期:2013-12-01 00:00:00
abstract::The majority of abnormal findings or lesions on T2-weighted fast spin-echo (FSE) magnetic resonance imaging (MRI) are hyperintense due to increased perfusion or fluid content, such as infections, tumours or synovitis. Hypointense lesions on T2-weighted images (both fat-suppressed and non-fat-suppressed) are less commo...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-015-4027-2
更新日期:2016-07-01 00:00:00
abstract::The purpose was to assess changes in lactate content and other brain metabolites under visual stimulation in optical chiasm, optic radiations and occipital cortex using multiple voxel MR spectroscopy (MRS). 1H chemical shift imaging (CSI) examinations of transverse planes centered to include the above structures were ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2494-y
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To assess the relationship between white matter (WM) integrity and clinical variables in tinnitus patients using diffusion tensor imaging (DTI). METHODS:Sixty-seven tinnitus patients and 39 healthy controls were enrolled in this study. The tinnitus duration, laterality, pitch and characteristics, and two psy...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-4034-3
更新日期:2016-07-01 00:00:00
abstract::We report the case of a man in which a Hodgkin's lymphoma involved the ureter as the very first clinical situs of the disease. Ureteral involvement in lymphomas is very rare (0.86%-7% and 1%-16%, found in two studies, respectively, of cases of patients with lymphoma examined post mortem) and when it does occur it is s...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050677
更新日期:1999-01-01 00:00:00