Abstract:
OBJECTIVE:To test the feasibility of fat-selective GRE imaging using a spectral-spatial excitation technique for determination of intrahepatic lipid content (IHL) in obese adolescents. METHODS:Fat-selective MR imaging (1.5 T) was applied to record a single axial slice through a representative liver region within a single breath-hold. The sequence uses six equidistant slice-selective excitation pulses with binomial amplitude ratios to achieve high selectivity for lipid signals after appropriate shimming. IHL(MRI) content was quantified using signal intensity of adjacent subcutaneous adipose tissue. As the gold standard for IHL quantification, single-voxel stimulated echo magnetic resonance spectroscopy (MRS) was applied. IHL(MRS) was quantified using the water peak as a reference. RESULTS:Forty-five MR examinations could be performed, and IHL(MRS) content ranged from 0.7% to 19.1%. Results from MRS and fat-selective imaging correlated well with Spearman coefficients between r = 0.78 and r = 0.86. There were no relevant regional differences in IHL within the liver parenchyma (p > 0.6359). Fat-selective imaging was able to reliably identify patients with IHL content above 5% with positive/negative likelihood ratio of 11.8 and 0.05, respectively. CONCLUSION:Fat-selective MR imaging provides both a reliable and a convenient method of rapidly quantifying IHL content in obese adolescents.
journal_name
Eur Radioljournal_title
European radiologyauthors
Springer F,Ehehalt S,Sommer J,Ballweg V,Machann J,Binder G,Claussen CD,Schick F,DISKUS-Study Group.doi
10.1007/s00330-010-1975-4subject
Has Abstractpub_date
2011-04-01 00:00:00pages
816-22issue
4eissn
0938-7994issn
1432-1084journal_volume
21pub_type
杂志文章abstract::We assessed the value of three-dimensional (3D) dynamic magnetic resonance angiography (MRA) for the follow-up of patients with radiosurgically treated cerebral arteriovenous malformations (AVMs). Fifty-four patients with cerebral AVMs treated by radiosurgery (RS) were monitored using conventional catheter angiography...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-005-0011-6
更新日期:2006-03-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
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journal_title:European radiology
pub_type: 临床试验,杂志文章
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journal_title:European radiology
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pub_type: 杂志文章
doi:10.1007/s00330-018-5325-2
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pub_type: 杂志文章
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journal_title:European radiology
pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章,meta分析
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更新日期:2010-12-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章,多中心研究
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journal_title:European radiology
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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