Antifungal activity of interleukin-2-activated natural killer (NK1.1+) lymphocytes against Candida albicans.

Abstract:

:Interleukin-2 (IL-2)-activated lymphocytes interact directly with, and inhibit, the growth of Candida albicans hyphae. C. albicans-stimulated natural killer (NK1.1+) lymphocytes were demonstrated to secrete a soluble product capable of directly affecting C. albicans yeast forms. Antibodies specific for interferon-gamma completely eliminated the antifungal activity of the NK1.1+ lymphocyte product and diminished the antifungal activity of NK1.1+ lymphocytes against C. albicans. Antibodies specific for other cytokines had no such effect. These data demonstrate that C. albicans-stimulated NK1.1+ lymphocytes have antifungal activity against C. albicans yeast cells via the release of interferon-gamma. This antifungal activity was demonstrable only against the yeast form of the fungus, with no effect on C. albicans hyphae.

journal_name

J Med Microbiol

authors

Mathews HL,Witek-Janusek L

doi

10.1099/00222615-47-11-1007

subject

Has Abstract

pub_date

1998-11-01 00:00:00

pages

1007-14

issue

11

eissn

0022-2615

issn

1473-5644

journal_volume

47

pub_type

杂志文章
  • Spread of the Brazilian epidemic clone of a multiresistant MRSA in two cities in Argentina.

    abstract::Methicillin-resistant Staphylococcus aureus (MRSA) is recognised as an important cause of nosocomial infection. The spread of some MRSA epidemic clones is well documented. In Brazil, and more recently in Portugal, a considerable number of hospital infections has been caused by a unique multiresistant MRSA clone design...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/0022-1317-49-2-187

    authors: Coimbra MVDS,Teixeira LA,Ramos RLB,Predari SC,Castello L,Famiglietti A,Vay C,Klan L,Figueiredo AMS

    更新日期:2000-02-01 00:00:00

  • Histoplasma capsulatum in planktonic and biofilm forms: in vitro susceptibility to amphotericin B, itraconazole and farnesol.

    abstract::It is believed that most microbial infections are caused by pathogens organized in biofilms. Recently, it was shown that the dimorphic fungus Histoplasma capsulatum, estimated to be the most common cause of fungal respiratory diseases, is also able to form biofilm. Although the antifungal therapy commonly used is effe...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000030

    authors: Brilhante RSN,de Lima RAC,Marques FJF,Silva NF,Caetano ÉP,Castelo-Branco DSCM,Bandeira TJPG,Moreira JLB,Cordeiro RA,Monteiro AJ,Camargo ZP,Sidrim JJC,Rocha MFG

    更新日期:2015-04-01 00:00:00

  • Francisella tularensis: unravelling the secrets of an intracellular pathogen.

    abstract::Francisella tularensis has been recognized as the causative agent of tularaemia for almost a century. Since its discovery in 1911, it has been shown to infect a wide range of hosts, including humans. As early as the 1920s it was suggested to be an intracellular pathogen, but it has proven to be an enigmatic organism, ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.1099/jmm.0.2008/000653-0

    authors: Oyston PCF

    更新日期:2008-08-01 00:00:00

  • Combined genomarkers approach to Salmonella characterization reveals that nucleotide sequence differences in the phase 1 flagellin gene fliC are markers for variation within serotypes.

    abstract::The characterization and tracking of pathogenic micro-organisms in the clinical laboratory and public health environment demand schemes that are easy to standardize and use, are automated and high-throughput, and provide portable data. A combined genomarkers approach for Salmonella enterica based on comparative sequen...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.047431-0

    authors: Bishop C,Honisch C,Goldman T,Mosko M,Keng S,Arnold C,Gharbia S

    更新日期:2012-11-01 00:00:00

  • Correlation between serum reactivity to Demodex-associated Bacillus oleronius proteins, and altered sebum levels and Demodex populations in erythematotelangiectatic rosacea patients.

    abstract::Rosacea is a chronic inflammatory condition that affects the skin of the face and the eyes. The aetiology of rosacea is not clearly established but increasing evidence suggests a potential role for bacteria in the induction of the condition. A role for Bacillus oleronius, originally isolated from within a Demodex foll...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.065136-0

    authors: Jarmuda S,McMahon F,Żaba R,O'Reilly N,Jakubowicz O,Holland A,Szkaradkiewicz A,Kavanagh K

    更新日期:2014-02-01 00:00:00

  • Prevalence of erythromycin and clindamycin resistance among clinical isolates of the Streptococcus anginosus group in Germany.

    abstract::Members of the Streptococcus anginosus group (SAG) are frequently involved in pyogenic infections in humans. In the present study, the antimicrobial susceptibility of 141 clinical SAG isolates to six antimicrobial agents was analysed by agar dilution. All isolates were susceptible to penicillin, cefotaxime and vancomy...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.001560-0

    authors: Asmah N,Eberspächer B,Regnath T,Arvand M

    更新日期:2009-02-01 00:00:00

  • Importance of Providencia species as a major cause of travellers' diarrhoea.

    abstract::In this study the importance of Providencia species as a cause of travellers' diarrhoea was examined using a selective medium developed by the authors. Providencia species could easily be distinguished from other enteric pathogens by the colour of the colonies obtained. Nine strains of Providencia alcalifaciens, nine ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.45846-0

    authors: Yoh M,Matsuyama J,Ohnishi M,Takagi K,Miyagi H,Mori K,Park KS,Ono T,Honda T

    更新日期:2005-11-01 00:00:00

  • Biocompatible biodegradable polymeric antibacterial nanoparticles for enhancing the effects of a third-generation cephalosporin against resistant bacteria.

    abstract:PURPOSE:In the present study, enhancement of the the antibacterial activity of ceftriaxone against Gram-positive (meticillin-resistant Staphylococcus aureus; MRSA) and Gram-negative (Escherichia coli) bacteria with a biodegradable polymer was attempted. METHODOLOGY:MRSA and E. coli were collected and identified by bio...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000445

    authors: Mushtaq S,Khan JA,Rabbani F,Latif U,Arfan M,Yameen MA

    更新日期:2017-03-01 00:00:00

  • Production of mouse monoclonal antibodies to Pasteurella multocida type A and the immunological properties of a protective anti-lipopolysaccharide antibody.

    abstract::Eight monoclonal antibodies (MAbs) were produced from mice immunised with whole cells of heat-killed Pasteurella multocida type A which had been cultured under iron-restricted conditions. The MAbs were selected by an enzyme-linked immunosorbent assay (ELISA) in which the antigen consisted of whole bacteria of the immu...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-33-4-217

    authors: Wijewardana TG,Wilson CF,Gilmour NJ,Poxton IR

    更新日期:1990-12-01 00:00:00

  • Improved rapid molecular diagnosis of multidrug-resistant tuberculosis using a new reverse hybridization assay, REBA MTB-MDR.

    abstract::Rapid diagnosis of multidrug-resistant tuberculosis (MDR-TB) is essential for the prompt initiation of effective second-line therapy to improve treatment outcome and limit transmission of this obstinate disease. A variety of molecular methods that enable the rapid detection of mutations implicated in MDR-TB have been ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.032292-0

    authors: Bang H,Park S,Hwang J,Jin H,Cho E,Kim DY,Song T,Shamputa IC,Via LE,Barry CE,Cho SN,Lee H

    更新日期:2011-10-01 00:00:00

  • Saksenaea erythrospora infection following a serious sailing accident.

    abstract::Saksenaea erythrospora is a species of the order Mucorales recently described and reported as a cause of human mucormycosis. We report a case of S. erythrospora in a man involved in a serious sailing accident causing deep skin and soft tissue contamination with soil and water. Direct microscopic examination of the cli...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.062174-0

    authors: Relloso S,Romano V,Landaburu MF,Herrera F,Smayevsky J,Veciño C,Mujica MT

    更新日期:2014-02-01 00:00:00

  • Cloning and sequencing the endocarditis immunodominant antigen of Streptococcus sobrinus strain MUCOB 263.

    abstract::Immunoblotting sera from cases of Streptococcus mutans or S. sobrinus endocarditis against an extract from S. sobrinus strain MUCOB 263 had identified three immunodominant antigenic bands at 190, 200 and 220 kDa. A lambda ZAPII DNA library was produced from the sheared genomic DNA of S. sobrinus MUCOB 263 and six iden...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-40-5-330

    authors: Brooks W,Burnie JP

    更新日期:1994-05-01 00:00:00

  • The effect of capsular polysaccharide and lipopolysaccharide of Bacteroides fragilis on polymorph function and serum killing.

    abstract::The determinant responsible for the ability of Bacteroides spp. to inhibit polymorph phagocytic killing of aerobic organisms has not yet been identified. Therefore, the roles of lipopolysaccharide and capsular polysaccharide of B. fragilis were investigated. Serum-resistant and serum-sensitive strains of Proteus mirab...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-17-3-259

    authors: Connolly JC,McLean C,Tabaqchali S

    更新日期:1984-06-01 00:00:00

  • Susceptibility of oral bacterial biofilms to antimicrobial agents.

    abstract::There is great interest in the use of antimicrobial agents for the prevention and treatment of plaque-related oral diseases and many publications have reported the results of studies in which the minimum inhibitory concentrations of agents for cariogenic and periodontopathogenic bacteria have been determined. However,...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.1099/00222615-44-2-79

    authors: Wilson M

    更新日期:1996-02-01 00:00:00

  • Immunological detection of Bacteroides fragilis in clinical samples.

    abstract::A monospecific polyclonal antiserum, prepared against Bacteroides fragilis common polysaccharide antigen purified by polyacrylamide gel immunoblot detected B. fragilis, B. thetaiotaomicron, B. ovatus and Prevotella melaninogenica in pus samples from various anatomical sites by immunofluorescence microscopy of the pus....

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-43-2-99

    authors: Patrick S,Stewart LD,Damani N,Wilson KG,Lutton DA,Larkin MJ,Poxton I,Brown R

    更新日期:1995-08-01 00:00:00

  • Lack of correlation between haemagglutination and adherence to epithelial cells in Yersinia pseudotuberculosis.

    abstract::Yersinia pseudotuberculosis was examined for its haemagglutinating activity and adherence to cultured epithelial cells (HEp-2) in relation to possession of a virulence (VW) plasmid and to growth conditions. VW-lacking (VW-) bacteria were isolated from ten VW+ strains of each serovar which, after they were grown on CFA...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-25-3-175

    authors: Kawaoka Y,Mitani T,Hoshina K,Otsuki K,Tsubokura M

    更新日期:1988-03-01 00:00:00

  • A mechanism of pathogenicity of "Streptococcus milleri group" in pulmonary infection: synergy with an anaerobe.

    abstract::The relationship between Streptococcus constellatus, one of the species of the "Streptococcus milleri group", and Prevotella intermedia was studied in a model of pneumonia in mice and in vitro to elucidate mechanisms of pathogenicity in "S. milleri group"-associated pulmonary infection. Acute pneumonia with or without...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-40-2-118

    authors: Shinzato T,Saito A

    更新日期:1994-02-01 00:00:00

  • Disseminated intravascular coagulation in rabbits: synergistic activity of meningococcal endotoxin and materials egested from leucocytes containing meningococci.

    abstract::Leucocyte-egested material was harvested after the quantitative in-vitro phagocytosis of Neisseria meningitidis by rabbit or mouse polymorphonuclear leucocytes. The egested material was injected subcutaneously into rabbits and followed 24 h later with an intravenous injection of what would by itself have been a non-le...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-9-4-451

    authors: DeVoe IW,Gilka F

    更新日期:1976-11-01 00:00:00

  • Streptococcus gordonii pheromone s.g.cAM373 may influence the reservoir of antibiotic resistance determinants of Enterococcus faecalis origin in the oral metagenome.

    abstract::Streptococcus gordonii produces a pheromone heptapeptide, s.g.cAM373, which induces a conjugative mating response in Enterococcus faecalis cells carrying the responsive plasmid, pAM373. We investigated the extent of this intergeneric signaling on DNA acquisition by streptococcal species likely to cohabit oral biofilms...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000613

    authors: Mansfield JM,Herrmann P,Jesionowski AM,Vickerman MM

    更新日期:2017-11-01 00:00:00

  • In vitro antifungal activities of amphotericin B in combination with acteoside, a phenylethanoid glycoside from Colebrookea oppositifolia.

    abstract::This study was undertaken to investigate the synergistic interaction between amphotericin B (AmB) and acteoside, isolated from the aerial parts of the shrub Colebrookea oppositifolia (Lamiaceae). Acteoside alone exhibited no intrinsic antifungal activity but showed a potent synergism in combination with AmB against se...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.031906-0

    authors: Ali I,Sharma P,Suri KA,Satti NK,Dutt P,Afrin F,Khan IA

    更新日期:2011-09-01 00:00:00

  • Candida krusei: biology, epidemiology, pathogenicity and clinical manifestations of an emerging pathogen.

    abstract::Early reports of Candida krusei in man describe the organism as a transient, infrequent isolate of minor clinical significance inhabiting the mucosal surfaces. More recently it has emerged as a notable pathogen with a spectrum of clinical manifestations such as fungaemia, endophthalmitis, arthritis and endocarditis, m...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.1099/00222615-41-5-295

    authors: Samaranayake YH,Samaranayake LP

    更新日期:1994-11-01 00:00:00

  • Occurrence of K1, K5 and O antigens in Escherichia coli isolates from patients with urinary tract infections or bacteraemia.

    abstract::The distribution of K1, K5 and O antigens was examined in 500 clinical strains of Escherichia coli. Of 400 strains from urine, 52% belonged to serogroups O1, O2, O4, O6, O7, O8, O9, O18, O25 and O75; 34% were non-typable (NT) and 14% were autoagglutinable (AA). Antigen K1 was carried by 17% of these strains, and K5 by...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-30-4-295

    authors: Devine DA,Robinson L,Roberts AP

    更新日期:1989-12-01 00:00:00

  • Helicobacter marmotae and novel Helicobacter and Campylobacter species isolated from the livers and intestines of prairie dogs.

    abstract::Prairie dogs (Cynomys ludovicianus) are used to study the aetiology and prevention of gallstones because of the similarities of prairie dog and human bile gallstone composition. Epidemiological and experimental studies have suggested a connection between infection with Helicobacter species and cholesterol cholelithias...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.032144-0

    authors: Beisele M,Shen Z,Parry N,Mobley M,Taylor NS,Buckley E,Abedin MZ,Dewhirst FE,Fox JG

    更新日期:2011-09-01 00:00:00

  • Characterization of a colistin-resistant Avian Pathogenic Escherichia coli ST69 isolate recovered from a broiler chicken in Germany.

    abstract::In recent years, several plasmids harbouring genes encoding phosphoethanolamine transferases conferring colistin resistance have been described in multiple Enterobacteriaceae species. Avian Pathogenic E. coli (APEC) causes colibacillosis and is responsible for a considerable proportion of the disease burden in commerc...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.000882

    authors: Hornsey M,Betts JW,Mehat JW,Wareham DW,van Vliet AHM,Woodward MJ,La Ragione RM

    更新日期:2019-01-01 00:00:00

  • Association of Aeromonas spp. with travellers' diarrhoea in Finland.

    abstract::The association of Aeromonas spp. with travellers' diarrhoea was studied among 978 Finnish tourists travelling to Morocco in winter (n = 398) and autumn (n = 580) in 1989. Fifty-five isolates from diarrhoeal patients with (n = 16) or without (n = 39) a recent travelling history in a developing country were also includ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-42-1-26

    authors: Hänninen ML,Salmi S,Mattila L,Taipalinen R,Siitonen A

    更新日期:1995-01-01 00:00:00

  • Identification by PCR of Helicobacter pylori in subgingival plaque of adult periodontitis patients.

    abstract::The PCR was used to detect the presence of Helicobacter pylori in subgingival plaque samples from patients with adult periodontitis. Primers based upon the 16S ribosomal RNA (rRNA) gene sequence of H. pylori were used in a single round of PCR to amplify a 295-bp DNA fragment and the identity of the amplified products ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-48-3-317

    authors: Riggio MP,Lennon A

    更新日期:1999-03-01 00:00:00

  • Apoptosis-like death in Leishmania donovani promastigotes induced by eugenol-rich oil of Syzygium aromaticum.

    abstract::Leishmaniasis consists of a complex spectrum of infectious diseases with worldwide distribution of which visceral leishmaniasis or kala-azar caused by Leishmania donovani is the most devastating. In the absence of vaccines, chemotherapy remains the mainstay for the control of leishmaniasis. The drugs of choice are exp...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.064709-0

    authors: Islamuddin M,Sahal D,Afrin F

    更新日期:2014-01-01 00:00:00

  • Outbreak of Klebsiella pneumoniae carbapenemase 2-producing K. pneumoniae with high qnr prevalence in a Chinese hospital.

    abstract::Forty carbapenem-resistant Klebsiella pneumoniae isolates were recovered from 28 patients from various sites in an intensive care unit in Zhejiang Provincial People's Hospital, China, over a 6 month period. PFGE analysis indicated that the 40 strains were all closely related. The MICs of carbapenems varied from 16 to ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/jmm.0.015826-0

    authors: Zhang R,Wang XD,Cai JC,Zhou HW,Lv HX,Hu QF,Chen GX

    更新日期:2011-07-01 00:00:00

  • Effect of carbon dioxide on the growth and form of Candida albicans.

    abstract::The effect of CO2 on the growth of 31 strains of Candida albicans was studied in serum and in a defined medium containing urea, ammonium chloride, asparagine, glutamine or acetamide as the nitrogen source. CO2 10% enhanced the mycelial growth of all strains when the medium contained an appropriate constituent to media...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-22-3-203

    authors: Sims W

    更新日期:1986-11-01 00:00:00

  • Oligofructose contributes to the protective role of bifidobacteria in experimental necrotising enterocolitis in quails.

    abstract::Bifidobacteria are dominant in the gut of full-term infants, although colonisation by them is often delayed in preterm neonates. Bifidobacteria are recognised to have beneficial effects on digestive disorders and they might prevent neonatal necrotising enterocolitis (NEC), a gastrointestinal disease that predominantly...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章

    doi:10.1099/00222615-48-1-89

    authors: Catala I,Butel MJ,Bensaada M,Popot F,Tessedre AC,Rimbault A,Szylit O

    更新日期:1999-01-01 00:00:00