Noninvasive monitoring of cardiac output in critically ill patients using transesophageal Doppler.

abstract：RATIONALE:Exhaled carbon monoxide (CO) and arterial blood carboxyhemoglobin concentrations (Hb-CO) increase in inflammatory pulmonary diseases. OBJECTIVES:To study whether arterial Hb-CO is useful to monitor disease activity in patients with chronic obstructive pulmonary disease (COPD) who had stopped smoking. METHOD...

journal_title：American journal of respiratory and critical care medicine

authors： Yasuda H,Yamaya M,Nakayama K,Ebihara S,Sasaki T,Okinaga S,Inoue D,Asada M,Nemoto M,Sasaki H

更新日期：2005-06-01 00:00:00

abstract：:Long-term effects of high doses of inhaled corticosteroids (ICS) on bone density and metabolism are still uncertain. Fifty-one patients (37 male, 14 female) using beclomethasone or budesonide at a daily dose > 800 microgram/d (high-dose group [Group HD] mean: 983 microgram/d [prescribed dose x estimated compliance]) o...

journal_title：American journal of respiratory and critical care medicine

authors： Boulet LP,Milot J,Gagnon L,Poubelle PE,Brown J

更新日期：1999-03-01 00:00:00

abstract：:Dobutamine has been proposed as a means of disclosing a pathologic oxygen supply (DO2) dependency in critically ill patients. Like other catecholamines, however, dobutamine might increase cellular metabolism, so that oxygen consumption (VO2) would increase regardless of the presence or absence of a supply dependency. ...

journal_title：American journal of respiratory and critical care medicine

authors： De Backer D,Moraine JJ,Berre J,Kahn RJ,Vincent JL

更新日期：1994-07-01 00:00:00

abstract：:To investigate the mechanisms underlying ventilator-dependence in patients with chronic obstructive pulmonary disease (COPD), and to assess the effects of the combination of positive end-expiratory pressure (PEEP) and pressure-support ventilation (PSV) on inspiratory muscle effort, we investigated respiratory mechanic...

journal_title：American journal of respiratory and critical care medicine

authors： Appendini L,Purro A,Patessio A,Zanaboni S,Carone M,Spada E,Donner CF,Rossi A

更新日期：1996-11-01 00:00:00

abstract：:The aim of this study was to assess the influence of preservation solution type and extra- or intracellular composition on the occurrence of early graft dysfunction after clinical lung transplantation. For 170 patients who underwent a single (n = 124) or bilateral (n = 46) lung transplantation in two centers in Paris ...

journal_title：American journal of respiratory and critical care medicine

authors： Thabut G,Vinatier I,Brugière O,Lesèche G,Loirat P,Bisson A,Marty J,Fournier M,Mal H

更新日期：2001-10-01 00:00:00

abstract：RATIONALE:In the absence of a surgical lung biopsy, patients diagnosed with idiopathic pulmonary fibrosis (IPF) in clinical practice could participate in the INPULSIS trials of nintedanib if they had honeycombing and/or traction bronchiectasis plus reticulation, without atypical features of usual interstitial pneumonia...

journal_title：American journal of respiratory and critical care medicine

authors： Raghu G,Wells AU,Nicholson AG,Richeldi L,Flaherty KR,Le Maulf F,Stowasser S,Schlenker-Herceg R,Hansell DM

更新日期：2017-01-01 00:00:00

abstract：:A study was done to compare the efficacy and safety of the coprescription of salmeterol 50 microgram twice daily or 100 microgram twice daily with beclomethasone dipropionate (BDP) 500 micrograms twice daily (SALM 50 and SALM 100) with BDP 1,000 microgram twice daily (BDP 1,000) in patients with asthma not controlled ...

journal_title：American journal of respiratory and critical care medicine

authors： Woolcock A,Lundback B,Ringdal N,Jacques LA

更新日期：1996-05-01 00:00:00

abstract：:11beta-hydroxysteroid dehydrogenases (11beta-HSD) are responsible for the conversion of bioactive glucocorticoids to and from inactive metabolites. 11beta-HSD2 is generally considered a high-affinity inactivator of natural glucocorticoids, although its activity with synthetic compounds in vivo is unknown. Inhaled cort...

journal_title：American journal of respiratory and critical care medicine

authors： Orsida BE,Krozowski ZS,Walters EH

更新日期：2002-04-01 00:00:00

abstract：:Several modalities of ventilatory support have been proposed to gradually withdraw patients from mechanical ventilation, but their respective effects on the outcome of weaning from mechanical ventilation are not known. We conducted a randomized trial in three intensive care units in mechanically ventilated patients wh...

journal_title：American journal of respiratory and critical care medicine

authors： Brochard L,Rauss A,Benito S,Conti G,Mancebo J,Rekik N,Gasparetto A,Lemaire F

更新日期：1994-10-01 00:00:00

abstract：RATIONALE:There are no accepted blood-based biomarkers in chronic obstructive pulmonary disease (COPD). Pulmonary and activation-regulated chemokine (PARC/CCL-18) is a lung-predominant inflammatory protein that is found in serum. OBJECTIVES:To determine whether PARC/CCL-18 levels are elevated and modifiable in COPD an...

journal_title：American journal of respiratory and critical care medicine

authors： Sin DD,Miller BE,Duvoix A,Man SF,Zhang X,Silverman EK,Connett JE,Anthonisen NA,Wise RA,Tashkin D,Celli BR,Edwards LD,Locantore N,Macnee W,Tal-Singer R,Lomas DA,ECLIPSE Investigators.

更新日期：2011-05-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is traditionally diagnosed using overnight polysomnography. Decision rules may provide an alternative to polysomnography. A consecutive series of patients referred to a tertiary sleep center underwent prospective evaluation with the upper airway physical examination protocol, followed by ...

journal_title：American journal of respiratory and critical care medicine

authors： Tsai WH,Remmers JE,Brant R,Flemons WW,Davies J,Macarthur C

更新日期：2003-05-15 00:00:00

abstract：:We investigated the relationship between annual change in pulmonary function and changes in respiratory symptoms among male grain elevator workers who participated in a health surveillance program mandated by Labour Canada. The surveillance was conducted every 3 yr starting from the period 1978 to 1981. The 1,211 work...

journal_title：American journal of respiratory and critical care medicine

authors： Senthilselvan A,Pahwa P,Wang P,McDuffie HH,Dosman JA

更新日期：1996-02-01 00:00:00

abstract：:In anaphylactic shock (AS), the relative effects of the autacoids including histamine, prostaglandins, and leukotrienes on causing cardiovascular collapse and the extent to which receptor blocking agents and pathway inhibitors may prevent this collapse are not clear. In a ragweed model of anaphylaxis, we examined whet...

journal_title：American journal of respiratory and critical care medicine

authors： Chrusch C,Sharma S,Unruh H,Bautista E,Duke K,Becker A,Kepron W,Mink SN

更新日期：1999-10-01 00:00:00

abstract：:The rise in childhood asthma prevalence suggests a role for environmental factors in the etiology of this evolving epidemic; however, genetics also influence the occurrence of asthma. Glutathione S-transferase (GST) M1 may play a role in asthma and wheezing occurrence among those exposed to tobacco smoke, as it functi...

journal_title：American journal of respiratory and critical care medicine

authors： Gilliland FD,Li YF,Dubeau L,Berhane K,Avol E,McConnell R,Gauderman WJ,Peters JM

更新日期：2002-08-15 00:00:00

abstract：:The aim of the study was to investigate the effect of addition of montelukast to inhaled fluticasone propionate (FP) therapy, compared with FP therapy alone (100 microg twice a day) on airway immunopathology in individuals with mild asthma. Twenty-eight subjects received FP (100 microg twice a day) or FP (100 microg t...

journal_title：American journal of respiratory and critical care medicine

authors： O'Sullivan S,Akveld M,Burke CM,Poulter LW

更新日期：2003-03-01 00:00:00

abstract：RATIONALE:Standard physiologic assessments of extubation readiness in patients with acute hypoxemic respiratory failure (AHRF) may not reflect lung injury resolution and could adversely affect clinical decision-making and patient outcomes. OBJECTIVES:We hypothesized that elevations in inflammatory plasma biomarkers so...

journal_title：American journal of respiratory and critical care medicine

authors： Alladina J,Levy SD,Cho JL,Brait KL,Rao SR PhD,Camacho A,Hibbert KA,Harris RS,Medoff BD,Januzzi JL,Thompson BT,Bajwa EK

更新日期：2021-01-05 00:00:00

abstract：RATIONALE:5-Hydroxytryptamine (5-HT) is involved in the pathogenesis of allergic airway inflammation (AAI). It is unclear, however, how 5-HT contributes to AAI and whether this depends on tryptophan hydroxylase (TPH) 1, the critical enzyme for peripheral 5-HT synthesis. OBJECTIVES:To elucidate the role of TPH1 and the...

journal_title：American journal of respiratory and critical care medicine

authors： Dürk T,Duerschmied D,Müller T,Grimm M,Reuter S,Vieira RP,Ayata K,Cicko S,Sorichter S,Walther DJ,Virchow JC,Taube C,Idzko M

更新日期：2013-03-01 00:00:00

abstract：:Respiratory system compliance (Crs) in infants with cystic fibrosis (CF) has been reported as decreased or not different compared with healthy control subjects; however, the reported measurements of Crs were "quasi-static" or by the single-breath occlusion technique, with all measurements limited to tidal lung volume,...

journal_title：American journal of respiratory and critical care medicine

authors： Tepper RS,Weist A,Williams-Nkomo T,Kisling J

更新日期：2004-09-01 00:00:00

abstract：:A continuously mixed series of microbial communities inhabits various points of the respiratory tract, with community composition determined by distance from colonization sources, colonization rates, and extinction rates. Ecology and evolution theory developed in the context of biogeography is relevant to clinical mic...

journal_title：American journal of respiratory and critical care medicine

authors： Whiteson KL,Bailey B,Bergkessel M,Conrad D,Delhaes L,Felts B,Harris JK,Hunter R,Lim YW,Maughan H,Quinn R,Salamon P,Sullivan J,Wagner BD,Rainey PB

更新日期：2014-06-01 00:00:00

abstract：:Chronic beryllium disease (CBD) provides a model system in which to evaluate the antigen-stimulated, cell-mediated, immune response that leads to granulomatous lung disease. We hypothesized that beryllium salts would stimulate bronchoalveolar lavage (BAL) cell release of tumor necrosis factor-alpha (TNF-alpha) and lnt...

journal_title：American journal of respiratory and critical care medicine

authors： Tinkle SS,Newman LS

更新日期：1997-12-01 00:00:00

abstract：:The expression of renin-angiotensin system components and the elevation of angiotensin-converting enzyme (ACE) in a number of fibrotic lung diseases suggests angiotensin II (AII) could play a role in the pathogenesis of pulmonary fibrosis. However, the effect of AII on lung fibroblasts has not previously been assessed...

journal_title：American journal of respiratory and critical care medicine

authors： Marshall RP,McAnulty RJ,Laurent GJ

更新日期：2000-06-01 00:00:00

abstract：RATIONALE:Asthma treatment might improve when inhaled steroids are titrated on airway inflammation. Fractional exhaled nitric oxide (FeNO0.05), a marker of eosinophilic airway inflammation, can be measured at home. OBJECTIVES:We assessed daily FeNO0.05 telemonitoring in the management of childhood asthma. METHODS:Chi...

journal_title：American journal of respiratory and critical care medicine

authors： de Jongste JC,Carraro S,Hop WC,CHARISM Study Group.,Baraldi E

更新日期：2009-01-15 00:00:00

abstract：:The present prospective study was designed to determine the prevalence of pleural effusion at approximately 28 days after cardiac surgery and their subsequent course. This consecutive case study included 389 patients; 312 had only coronary artery bypass graft surgery (CABG) surgery, 37 had both valve and CABG surgery,...

journal_title：American journal of respiratory and critical care medicine

authors： Light RW,Rogers JT,Moyers JP,Lee YC,Rodriguez RM,Alford WC Jr,Ball SK,Burrus GR,Coltharp WH,Glassford DM Jr,Hoff SJ,Lea JW 4th,Nesbitt JC,Petracek MR,Starkey TD,Stoney WS,Tedder M

更新日期：2002-12-15 00:00:00

abstract：RATIONALE:Dyspnea is the impairing cardinal symptom of asthma but its accurate perception is also crucial for timely initiation of treatment. However, the underlying brain mechanisms of perceived dyspnea in patients with asthma are unknown. OBJECTIVES:To study brain mechanisms of dyspnea in asthma. METHODS:By using f...

journal_title：American journal of respiratory and critical care medicine

authors： von Leupoldt A,Sommer T,Kegat S,Eippert F,Baumann HJ,Klose H,Dahme B,Büchel C

更新日期：2009-08-01 00:00:00

abstract：:We investigated the relationship between the extent of pulmonary emphysema, assessed by quantitative high-resolution computed tomography (HRCT), and lung mechanics in 24 patients with chronic obstructive pulmonary disease (COPD). The extent of emphysema was quantified as the relative lung area with CT numbers < -950 H...

journal_title：American journal of respiratory and critical care medicine

authors： Baldi S,Miniati M,Bellina CR,Battolla L,Catapano G,Begliomini E,Giustini D,Giuntini C

更新日期：2001-08-15 00:00:00

abstract：RATIONALE:Fibroblast growth factor receptor-1alpha(IIIc) [FGF-R1alpha(IIIc)] regulates recovery of neonatal rat lung growth, after 95% oxygen-mediated growth arrest. Its role in normal postnatal alveologenesis is unknown. OBJECTIVE:To determine if FGF-R1alpha(IIIc) regulates normal postnatal alveologenesis. METHODS:T...

journal_title：American journal of respiratory and critical care medicine

authors： Yi M,Belcastro R,Shek S,Luo D,Post M,Tanswell AK

更新日期：2006-09-01 00:00:00

abstract：:In mechanically ventilated patients, pressure and flow tracings can be used to assess respiratory pump muscle activity or rest. When the ventilation is delivered through an endotracheal tube, the respiratory system can be considered a one-compartment model, and activation of the respiratory muscles results in deformat...

journal_title：American journal of respiratory and critical care medicine

authors： Jounieaux V,Parreira VF,Delguste P,Aubert G,Rodenstein DO

更新日期：1997-06-01 00:00:00

abstract：:Snoring and sleeping apnea are reportedly associated with morbidity. We used home monitoring (MESAM IV) to measure snoring and sleep apnea in 294 men aged 40 to 65 yr from the volunteer register of the Busselton (Australia) Health Survey. In this group, 81% snored for more than 10% of the night and 22% for more than h...

journal_title：American journal of respiratory and critical care medicine

authors： Bearpark H,Elliott L,Grunstein R,Cullen S,Schneider H,Althaus W,Sullivan C

更新日期：1995-05-01 00:00:00

abstract：:Ventilation style influences lung injury and the amount of large-aggregate biophysically active surfactant in adult lungs. We asked how positive end-expiratory pressures (PEEP) would influence clinical responses and surfactant pools in surfactant-treated preterm lambs ventilated for 7 h with tidal volumes (VT) of 10 m...

journal_title：American journal of respiratory and critical care medicine

authors： Michna J,Jobe AH,Ikegami M

更新日期：1999-08-01 00:00:00

abstract：RATIONALE:New vaccines are urgently needed to protect the vulnerable from bacterial pneumonia. Clinical trials of pneumonia vaccines are slow and costly, requiring tens of thousands of patients. Studies of pneumococcal vaccine efficacy against colonization have been proposed as a novel method to down-select between vac...

journal_title：American journal of respiratory and critical care medicine

authors： Collins AM,Wright AD,Mitsi E,Gritzfeld JF,Hancock CA,Pennington SH,Wang D,Morton B,Ferreira DM,Gordon SB

更新日期：2015-10-01 00:00:00