The complementary role of glucocorticosteroids and long-acting beta-adrenergic agonists.

abstract：:Because humans breathe through the nose, the nasal mucosa becomes sensitized to inhalant allergens. Allergic rhinitis is, together with allergic conjunctivitis, the best example of a type I hypersensitivity reaction. It is an inflammation of the nasal mucosa induced by specific immune recognition of exogenous allergen...

journal_title：Allergy

authors： Van Cauwenberge PB

更新日期：1997-01-01 00:00:00

abstract：:During the last years, two new cardiovascular drug classes, namely inhibitors of DPP IV or neprilysin, have been developed. In both cases, there is clinical evidence for their potential to induce angioedema as known already from blockers of the renin-angiotensin-aldosterone system (RAAS). The majority of angioedema in...

journal_title：Allergy

authors： Bas M,Greve J,Strassen U,Khosravani F,Hoffmann TK,Kojda G

更新日期：2015-10-01 00:00:00

abstract：:There are studies demonstrating that skin-test sensitivity to penicillins can decrease over time and that allergic patients may lose sensitivity if the responsible compounds are avoided. With regard to subjects with IgE-mediated hypersensitivity to cephalosporins, however, such studies are lacking. We evaluated prospe...

journal_title：Allergy

authors： Romano A,Gaeta F,Valluzzi RL,Zaffiro A,Caruso C,Quaratino D

更新日期：2014-06-01 00:00:00

abstract：:Mast cell degranulation, and the subsequent recruitment of infiltrating inflammatory cells, such as eosinophils, into the nasal mucosa has long been considered the most important model to explain allergic rhinitis. Several studies show a decrease in the number of eosinophils and possibly also mast cells during local c...

journal_title：Allergy

authors： Godthelp T,Holm AF,Blom H,Klein-Jan A,Rijntjes E,Fokkens WJ

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:WHO guidelines advocate breastfeeding for 6 months, and EAACI guideline recommends exclusive breastfeeding for 4-6 months. However, evidence for breastfeeding to prevent asthma and allergic disease is conflicting. We examined whether following recommended breastfeeding guidelines alters the long-term risks o...

journal_title：Allergy

authors： Bion V,Lockett GA,Soto-Ramírez N,Zhang H,Venter C,Karmaus W,Holloway JW,Arshad SH

更新日期：2016-05-01 00:00:00

abstract：:Sublingual immunotherapy has been shown in some clinical studies to modulate allergen-specific antibody responses [with a decrease in the immunoglobulin E/immunoglobulin G4 (IgE/IgG4) ratio] and to reduce the recruitment and activation of proinflammatory cells in target mucosa. Whereas a central paradigm for successfu...

journal_title：Allergy

authors： Moingeon P,Batard T,Fadel R,Frati F,Sieber J,Van Overtvelt L

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Children with spina bifida (SB) are exposed to latex soon after birth during bladder catheterization, rectal disimpaction, and multiple surgical procedures. IgE-mediated latex-allergic reactions have been reported recently in these children. Our study was designed to assess the prevalence of allergic reactio...

journal_title：Allergy

authors： Kattan H,Harfi HA,Tipirneni P

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Synthetic bedding has been associated with increased child wheeze and also higher allergen levels in several studies. We aimed to examine whether the association between synthetic bedding and adverse respiratory outcomes was more evident among skin-prick test (SPT) positive children. METHODS:A cross-section...

journal_title：Allergy

authors： Ponsonby AL,Gatenby P,Glasgow N,Mullins R,Hurwitz M,McDonald T

更新日期：2002-03-01 00:00:00

abstract：:The relationship between asthma and obesity appears to be quite complex. The aim of this study was to assess the effect of excess weight on asthma control evolution in a cohort of asthmatics. A prospective database was set up, which enrolled adult asthmatics with persistent (mild, moderate or severe) asthma. The contr...

journal_title：Allergy

authors： Saint-Pierre P,Bourdin A,Chanez P,Daures JP,Godard P

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Nuclear factor kappaB (NF-kappaB) overactivation plays a crucial role in T-helper 2 (Th2)-biased allergic airway inflammation by increased activation and decreased apoptosis of CD4(+) T cells. We have shown that targeted NF-kappaB suppression in dendritic cells by adenoviral gene transfer of a novel mutated ...

journal_title：Allergy

authors： Zhou LF,Zhang MS,Hu AH,Zhu Z,Yin KS

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Partial mattress encasing was found to be effective in reducing exposure to mite allergen in our previous investigation. We aimed to compare the short-term efficacy of partial and complete mattress encasing and to study mite-allergen levels within these mattresses. METHODS:Thirty-one mattresses with high mi...

journal_title：Allergy

authors： Vichyanond P,Uthaisangsook S,Ruangruk S,Malainual N

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Sensitization to atopens is an early phenomenon that overlaps with the onset of atopic dermatitis (AD) in infancy. Early epidermal barrier impairment may facilitate the epicutaneous penetration of atopens. OBJECTIVE:To correlate transepidermal water loss (TEWL) and aeroallergen sensitization in infants with...

journal_title：Allergy

authors： Boralevi F,Hubiche T,Léauté-Labrèze C,Saubusse E,Fayon M,Roul S,Maurice-Tison S,Taïeb A

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Although asthma is characterized by variable airways obstruction, most studies of asthma phenotypes are cross-sectional. The stability of phenotypes defined either by biomarkers or by physiological variables was assessed by repeated measures over 1 year in the Pan-European BIOAIR cohort of adult asthmatics. ...

journal_title：Allergy

authors： Kupczyk M,Dahlén B,Sterk PJ,Nizankowska-Mogilnicka E,Papi A,Bel EH,Chanez P,Howarth PH,Holgate ST,Brusselle G,Siafakas NM,Gjomarkaj M,Dahlén SE,BIOAIR investigators.

更新日期：2014-09-01 00:00:00

abstract：:We present the results of allergen content evaluation in 80 dust samples from 31 homes of atopic patients from two climatic areas (humid and subhumid), collected in two seasons of the year (autumn and winter). Monoclonal antibody-based immunoassays were used to quantify Der p 1, Der f 1, Der 2, Lep d 1, and Fel d 1. T...

journal_title：Allergy

authors： Echechipía S,Ventas P,Audícana M,Urrutia I,Gastaminza G,Polo F,Fernández de Corres L

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Allergens from house dust mites (HDMs), Dermatophagoides pteronyssinus and Blomia tropicalis are clinically relevant in atopic respiratory diseases in tropical countries. AIMS OF THE STUDY:To evaluate immunoglobulin (Ig)E, IgG1, and IgG4 antibody responses to B. tropicalis in Brazilian atopic patients. MET...

journal_title：Allergy

authors： Pereira EA,Silva DA,Cunha-Júnior JP,Almeida KC,Alves R,Sung SJ,Taketomi EA

更新日期：2005-03-01 00:00:00

abstract：:Phospholipase A2 (E.C. 3.1.1.4.) is a major allergen of honey bee venom. It exists in a glycosylated and an unglycosylated variant. Both forms and the glycopeptide isolated after exhaustive proteolytic digestion were tested in RAST and RAST inhibition studies. IgE from 11 of 14 bee venom allergy sera exhibited signifi...

journal_title：Allergy

authors： Weber A,Schröder H,Thalberg K,März L

更新日期：1987-08-01 00:00:00

abstract：:In immunotherapy of grass pollen allergy, an extract of rye (Secale cereale) is often included. The aim of this study was to investigate by skin prick test (SPT) and immunochemical methods whether rye pollen contains specific allergens justifying the use of this extract separately. Twenty grass pollen allergic patient...

journal_title：Allergy

authors： Løwenstein H,Wihl JA,Bache Billesbølle K,Bøwadt H

更新日期：1984-08-01 00:00:00

abstract：:We investigated the prevalence of sensitization to the cat lipocalin Fel d 7 among 140 cat-sensitized Swedish patients and elucidated its allergenic activity and cross-reactivity with the dog lipocalin Can f 1. Sixty-five of 140 patients had IgE to rFel d 7 whereof 60 also had IgE to rCan f 1. A moderate correlation b...

journal_title：Allergy

authors： Apostolovic D,Sánchez-Vidaurre S,Waden K,Curin M,Grundström J,Gafvelin G,Cirkovic Velickovic T,Grönlund H,Thomas WR,Valenta R,Hamsten C,van Hage M

更新日期：2016-10-01 00:00:00

abstract：:Regulatory approaches for allergen immunotherapy (AIT) products and the availability of high-quality AIT products are inherently linked to each other. While allergen products are available in many countries across the globe, their regulation is very heterogeneous. First, we describe the regulatory systems applicable f...

journal_title：Allergy

authors： Bonertz A,Roberts GC,Hoefnagel M,Timon M,Slater JE,Rabin RL,Bridgewater J,Pini C,Pfaar O,Akdis C,Goldstein J,Poulsen LK,van Ree R,Rhyner C,Barber D,Palomares O,Sheikh A,Pawankar R,Hamerlijnk D,Klimek L,Agache I,

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Over 100 million people worldwide suffer from birch pollen allergy. Bet v 1 has been identified as the major birch pollen allergen. However, the molecular mechanisms of birch allergic sensitization, including the roles of Bet v 1 and other components of the birch pollen extract, remain incompletely understoo...

journal_title：Allergy

authors： Soh WT,Aglas L,Mueller GA,Gilles S,Weiss R,Scheiblhofer S,Huber S,Scheidt T,Thompson PM,Briza P,London RE,Traidl-Hoffmann C,Cabrele C,Brandstetter H,Ferreira F

更新日期：2019-12-01 00:00:00

abstract：:A variety of methods have been used to attempt to decrease the allergenicity of food products, with highly variable success. Limited knowledge of allergen and epitope structures and the factors governing their stability may explain this, and the ensuing need for an empirical approach. A combined effort from a processi...

journal_title：Allergy

authors： Soler-Rivas C,Wichers HJ

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Insect-bite hypersensitivity (IBH) in horses is a chronic allergic dermatitis caused by insect bites. Horses suffer from pruritic skin lesions, caused by type-I/type-IV allergic reactions accompanied by prominent eosinophil infiltration into the skin. Interleukin-5 (IL-5) is the key cytokine for eosinophils ...

journal_title：Allergy

authors： Fettelschoss-Gabriel A,Fettelschoss V,Olomski F,Birkmann K,Thoms F,Bühler M,Kummer M,Zeltins A,Kündig TM,Bachmann MF

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Ole e 7 is a nonspecific lipid transfer protein (nsLTP) from olive pollen, one of the main allergenic pollens worldwide. This allergenic nsLTP is responsible for severe symptoms in regions with high olive pollen exposure, where many Ole e 7-sensitized patients exhibit a co-sensitization to the peach nsLTP, P...

journal_title：Allergy

authors： Oeo-Santos C,Navas A,Benedé S,Ruíz-León B,Díaz-Perales A,Vogel L,Moreno-Aguilar C,Jurado A,Villalba M,Barderas R

更新日期：2020-04-01 00:00:00

abstract：:The aim of the study was to investigate whether topical application of a beta-2-adrenostimulant (fenoterol) on the mucous membrane has a clinically significant anti-allergic effect. Thirty-three patients with grass pollen hay fever completed the trial which was a double-blind, placebo-controlled cross-over design. Aft...

journal_title：Allergy

authors： Borum P,Larsen FS

更新日期：1987-02-01 00:00:00

abstract：:The aim of the present investigation was to study the dose response relationship of allergen, histamine and histamine releasers in skin prick test (SPT) and the precision of the SPT method. In one experiment timothy allergen, histamine HCl, rabbit anti-human-IgE and compound 48/80 were studied in seven patients. In a ...

journal_title：Allergy

authors： Dreborg S,Holgersson M,Nilsson G,Zetterström O

更新日期：1987-02-01 00:00:00

abstract：:In vitro challenge of peripheral white blood cells (WBC) from 62 food sensitive patients and 22 asymptomatic control individuals was performed using standardized extract of cow milk, corn and wheat. 81% of the patients reacted at least toward one food antigen, showing disintegration of WBC, as measured by trypan blue ...

journal_title：Allergy

authors： Podleski WK

更新日期：1985-04-01 00:00:00

abstract：:Antigen-presenting cells (APCs) of the human gut are heterogeneous, including both macrophages, a variety of dendritic cells and B cells. They are found both in gut-associated lymphoid tissue and in the mucosal lamina propria, especially beneath the surface epithelium. APCs have diverse phenotypes and therefore probab...

journal_title：Allergy

authors： Brandtzaeg P

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:CD40 and OX40 Ligand (OX40L) are cell-surface molecules expressed on airway smooth muscle (ASM) that can enhance inflammatory cell activation and survival. The aim of this study was to examine the effect of tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on ASM CD40 and OX40L expres...

journal_title：Allergy

authors： Krimmer DI,Loseli M,Hughes JM,Oliver BG,Moir LM,Hunt NH,Black JL,Burgess JK

更新日期：2009-07-01 00:00:00

abstract：:This study was conducted to evaluate how bronchial responsiveness to direct and indirect stimuli relate to nitric oxide producing airway inflammation, and whether the relationship differs between atopic and nonatopic patients with various degrees of bronchial hyperresponsiveness and airway inflammation in a group of o...

journal_title：Allergy

authors： Rouhos A,Ekroos H,Karjalainen J,Sarna S,Sovijärvi AR

更新日期：2005-12-01 00:00:00