Rationale for specific immunotherapy of grass pollen allergy with extracts of rye pollen. Skin test reactivity and immunochemical relationship between pollen allergens from rye and other common grasses.

Abstract:

:In immunotherapy of grass pollen allergy, an extract of rye (Secale cereale) is often included. The aim of this study was to investigate by skin prick test (SPT) and immunochemical methods whether rye pollen contains specific allergens justifying the use of this extract separately. Twenty grass pollen allergic patients were skin prick tested with a dialysed freeze-dried raw extract of rye pollen (Sc), timothy extract (Soluprick SQ, 1 HEP) and two other rye extracts (Soluprick). Sera from the patients were RAST-tested using Sc and timothy (Pp). CRIE was performed using Sc and rabbit-anti grass (aNG) antibodies. The antigenic relations between rye and common grasses were investigated by CLIE using Sc and aNG as references, and by RAST inhibition. The ability of aNG to absorb the allergen activity of Sc was also tested. Significant correlations were found between timothy and rye when compared by means of SPT and RAST. The immunochemical analyses did not reveal any rye antigens containing rye epitopes only. However, the possibility of rye antigens with several epitopes, of which at least one is specific for rye, could not be excluded. Clinical symptoms supposedly elicited by rye alone can be explained quantitatively by the strongly time-limited and concentrated natural exposition. Diagnosis and treatment can, however, be performed with extracts of common grasses.

journal_name

Allergy

journal_title

Allergy

authors

Løwenstein H,Wihl JA,Bache Billesbølle K,Bøwadt H

doi

10.1111/j.1398-9995.1984.tb01964.x

subject

Has Abstract

pub_date

1984-08-01 00:00:00

pages

421-32

issue

6

eissn

0105-4538

issn

1398-9995

journal_volume

39

pub_type

杂志文章

相关文献

ALLERGY文献大全
  • Priming and inducing effects of interleukin-3 on histamine release from cord-blood basophils.

    abstract::The effect of interleukin-3 (IL-3) on histamine release from cord and adult blood basophils were evaluated. Leukocyte suspensions, obtained from adult patients with respiratory allergy (n = 15), normal adult subjects (n = 15), and neonates with (n = 15) and without (n = 19) atopic disposition, were stimulated with ant...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1997.tb02419.x

    authors: Miadonna A,Salmaso C,Marco MP,Pugni L,Milazzo N,Tedeschi A,Marini A

    更新日期:1997-10-01 00:00:00

  • Safety and reproducibility of nasal allergen challenge.

    abstract:BACKGROUND:The nasal allergen challenge (NAC) is a useful tool for the diagnosis of allergic rhinitis (AR) and local allergic rhinitis (LAR) and might serve to design and monitor allergen immunotherapy. Nevertheless, data about its safety and reproducibility are scarce. OBJECTIVE:To investigate the safety and reproduc...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13728

    authors: Eguiluz-Gracia I,Testera-Montes A,González M,Pérez-Sánchez N,Ariza A,Salas M,Moreno-Aguilar C,Campo P,Torres MJ,Rondon C

    更新日期:2019-06-01 00:00:00

  • Specificity of ELISA for IgG subclass antibodies against inhalant antigens in early childhood.

    abstract::ELISA is increasingly used to measure antibodies in new circumstances. Recently, it has been applied to the measurement of IgG subclass antibodies against common antigens in early childhood. These studies have raised concerns about the specificity of some of these assays. This paper details the results of experiments ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1994.tb02093.x

    authors: Ruiz RG,Price JF,Kemeny DM

    更新日期:1994-10-01 00:00:00

  • Tape strips from early-onset pediatric atopic dermatitis highlight disease abnormalities in nonlesional skin.

    abstract:BACKGROUND:Skin biopsies promote our understanding of atopic dermatitis/AD pathomechanisms in infants/toddlers with early-onset AD, but are not feasible in pediatric populations. Tape strips are an emerging, minimally invasive alternative, but global transcriptomic profiling in early pediatric AD is lacking. We aimed t...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.14490

    authors: Pavel AB,Renert-Yuval Y,Wu J,Del Duca E,Diaz A,Lefferdink R,Fang MM,Canter T,Rangel SM,Zhang N,Krueger JG,Paller AS,Guttman-Yassky E

    更新日期:2021-01-01 00:00:00

  • Farm animal feeders: another group affected by cereal flour asthma.

    abstract::Asthma induced by cereal flour is a long recognized entity. We present studies of three patients affected by asthma related to exposure to cereal flour contained in animal formula feeds. Skin prick test performed with the formula feed components showed positive reactions to cereal flours (wheat, rye and barley) and ne...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1988.tb00909.x

    authors: Valdivieso R,Pola J,Zapata C,Puyana J,Cuesta J,Martin C,Losada E

    更新日期:1988-08-01 00:00:00

  • Allergy to jackfruit: a novel example of Bet v 1-related food allergy.

    abstract:BACKGROUND:Jackfruit allergy has been reported just once. It is unknown whether this food allergy is caused by direct sensitization or cross-sensitization to pollen allergens. OBJECTIVE:Establish whether jackfruit allergy is linked to birchpollen allergy. METHODS:Two jackfruit allergic patients and five patients with...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2004.00544.x

    authors: Bolhaar ST,Ree R,Bruijnzeel-Koomen CA,Knulst AC,Zuidmeer L

    更新日期:2004-11-01 00:00:00

  • Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients.

    abstract:BACKGROUND:Allergy is regarded as a multifactorial condition. Its onset and severity are influenced by both genetic and environmental factors. Identification of genetic factors involved in asthma development and related phenotypes is a major task in understanding the genetic background of asthma. The possible involveme...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2005.00619.x

    authors: Shin HD,Kim LH,Park BL,Choi YH,Park HS,Hong SJ,Choi BW,Lee JH,Park CS

    更新日期:2005-07-01 00:00:00

  • Immunology of atopic eczema: overcoming the Th1/Th2 paradigm.

    abstract::Atopic eczema (AE) is a challenge for modern medicine, because it is prevalent, severely affects quality of life of patients and their families, and causes high socioeconomic costs. The pathogenesis of AE is complex. While initial studies suggested a Th2 deviation as primary reason for the disease, numerous studies ad...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/all.12184

    authors: Eyerich K,Novak N

    更新日期:2013-08-01 00:00:00

  • Validation of the classification of ARIA (allergic rhinitis and its impact on asthma).

    abstract:BACKGROUND:Allergic rhinitis is commonly divided into seasonal and perennial rhinitis. The recent Allergic Rhinitis and its Impact on Asthma (ARIA) workshop proposes to replace these terms by intermittent vs persistent rhinitis. METHODS:In order to test the new ARIA classification against the classical one used in med...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2003.t01-1-00202.x

    authors: Demoly P,Allaert FA,Lecasble M,Bousquet J,PRAGMA.

    更新日期:2003-07-01 00:00:00

  • Food-induced cutaneous adverse reactions.

    abstract::The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intoler...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1398-9995.1998.tb04983.x

    authors: Wüthrich B

    更新日期:1998-01-01 00:00:00

  • IgE autoantibodies in atopic dermatitis--occurrence of different antibodies against the CH3 and the CH4 epitopes of IgE.

    abstract::Levels of "free" anti-IgE autoantibodies and IgE/anti-IgE immune complexes were measured in the sera of patients with atopic dermatitis before and after treatment, psoriasis patients, and nonatopic controls. In this measurement, we used two monoclonal antibodies with distinct in vitro functions (LE 27, BSW 17), direct...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1995.tb01141.x

    authors: Czech W,Stadler BM,Schôpf E,Kapp A

    更新日期:1995-03-01 00:00:00

  • Evaluating the efficacy of breastfeeding guidelines on long-term outcomes for allergic disease.

    abstract:BACKGROUND:WHO guidelines advocate breastfeeding for 6 months, and EAACI guideline recommends exclusive breastfeeding for 4-6 months. However, evidence for breastfeeding to prevent asthma and allergic disease is conflicting. We examined whether following recommended breastfeeding guidelines alters the long-term risks o...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12833

    authors: Bion V,Lockett GA,Soto-Ramírez N,Zhang H,Venter C,Karmaus W,Holloway JW,Arshad SH

    更新日期:2016-05-01 00:00:00

  • Hypersensitivity to cefuroxime with good tolerance to other betalactams.

    abstract::A 60-year-old man developed an anaphylactic reaction immediately after administration of intramuscular sodium cefuroxime. By means of oral controlled challenge, the reaction was reproduced with a smaller dose of cefuroxime axetil. Cross-reactivity with other betalactam antibiotics was ruled out by in vivo tests. This ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1995.tb01160.x

    authors: Marcos Bravo C,Luna Ortiz I,González Vázquez R

    更新日期:1995-04-01 00:00:00

  • IgE, IgG1, and IgG4 antibody responses to Blomia tropicalis in atopic patients.

    abstract:BACKGROUND:Allergens from house dust mites (HDMs), Dermatophagoides pteronyssinus and Blomia tropicalis are clinically relevant in atopic respiratory diseases in tropical countries. AIMS OF THE STUDY:To evaluate immunoglobulin (Ig)E, IgG1, and IgG4 antibody responses to B. tropicalis in Brazilian atopic patients. MET...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2005.00738.x

    authors: Pereira EA,Silva DA,Cunha-Júnior JP,Almeida KC,Alves R,Sung SJ,Taketomi EA

    更新日期:2005-03-01 00:00:00

  • Association of ambient air-pollution levels with acute asthma exacerbation among children in Singapore.

    abstract:BACKGROUND:Air-pollution levels have been shown to be associated with increased morbidity of respiratory diseases. METHODS:Data for ambient air-pollutant levels, meteorologic factors, and hospitalization or emergency room (ER) visits for acute asthma in Singapore children over a 5-year period (1990-4) were obtained an...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.1999.00012.x

    authors: Chew FT,Goh DY,Ooi BC,Saharom R,Hui JK,Lee BW

    更新日期:1999-04-01 00:00:00

  • Development and validation of the mastocytosis activity score.

    abstract:BACKGROUND:Mastocytosis is a heterogeneous disease characterized by a clonal expansion of mast cells in various organs. The vast majority of patients suffer from signs and symptoms caused by mediator release from mast cells. Although the disease burden is high, there is currently no specific and validated instrument to...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13425

    authors: Siebenhaar F,Sander B,Ho LHT,Ellrich A,Maurer M,Weller K

    更新日期:2018-07-01 00:00:00

  • Determining the negative predictive value of provocation tests with beta-lactams.

    abstract:BACKGROUND:The beta-lactam allergic work-up is mostly standardized. However, the negative predictive value of drug provocation tests is not yet well established. METHOD:A historical-prospective multicentre cohort study was conducted in four centres (one in France, one in Portugal, two in Italy) to assess the negative ...

    journal_title:Allergy

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1398-9995.2009.02228.x

    authors: Demoly P,Romano A,Botelho C,Bousquet-Rouanet L,Gaeta F,Silva R,Rumi G,Rodrigues Cernadas J,Bousquet PJ

    更新日期:2010-03-01 00:00:00

  • Effect of grass pollen immunotherapy on clinical and local immune response to nasal allergen challenge.

    abstract:RATIONALE:Nasal allergen provocations may be useful in investigating the pathophysiology of allergic rhinitis and effects of treatments. OBJECTIVE:To use grass pollen nasal allergen challenge (NAC) to investigate the effects of allergen immunotherapy in a cross-sectional study. METHODS:We studied nasal and cutaneous ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12608

    authors: Scadding GW,Eifan AO,Lao-Araya M,Penagos M,Poon SY,Steveling E,Yan R,Switzer A,Phippard D,Togias A,Shamji MH,Durham SR

    更新日期:2015-06-01 00:00:00

  • Specific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction.

    abstract:BACKGROUND:Specific oral tolerance induction (SOTI) seems to be a promising treatment of food allergy. Specific oral tolerance induction and elimination diet were compared with respect to efficacy rate and patterns of clinical reaction. METHODS:Children with challenge proven immunoglobulin E (IgE)-mediated cow's milk ...

    journal_title:Allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.2007.01501.x

    authors: Staden U,Rolinck-Werninghaus C,Brewe F,Wahn U,Niggemann B,Beyer K

    更新日期:2007-11-01 00:00:00

  • The management of anaphylaxis in childhood: position paper of the European academy of allergology and clinical immunology.

    abstract::Anaphylaxis is a growing paediatric clinical emergency that is difficult to diagnose because a consensus definition was lacking until recently. Many European countries have no specific guidelines for anaphylaxis. This position paper prepared by the EAACI Taskforce on Anaphylaxis in Children aims to provide practical g...

    journal_title:Allergy

    pub_type: 杂志文章,实务指引

    doi:10.1111/j.1398-9995.2007.01421.x

    authors: Muraro A,Roberts G,Clark A,Eigenmann PA,Halken S,Lack G,Moneret-Vautrin A,Niggemann B,Rancé F,EAACI Task Force on Anaphylaxis in Children.

    更新日期:2007-08-01 00:00:00

  • The influence of air conditioning, humidity, temperature and other household characteristics on mite allergen concentrations in the northeastern United States.

    abstract:BACKGROUND:Information about the influence of housing and occupant characteristics on mite allergen concentrations is crucial to determine which methods could be used to decrease exposure of susceptible subjects. OBJECTIVES:To identify housing and occupant characteristics that are associated with mite allergen concent...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2004.00470.x

    authors: van Strien RT,Gehring U,Belanger K,Triche E,Gent J,Bracken MB,Leaderer BP

    更新日期:2004-06-01 00:00:00

  • The association between synthetic bedding and adverse respiratory outcomes among skin-prick test positive and skin-prick test negative children.

    abstract:BACKGROUND:Synthetic bedding has been associated with increased child wheeze and also higher allergen levels in several studies. We aimed to examine whether the association between synthetic bedding and adverse respiratory outcomes was more evident among skin-prick test (SPT) positive children. METHODS:A cross-section...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2002.1s3234.x

    authors: Ponsonby AL,Gatenby P,Glasgow N,Mullins R,Hurwitz M,McDonald T

    更新日期:2002-03-01 00:00:00

  • Natural evolution of skin-test sensitivity in patients with IgE-mediated hypersensitivity to cephalosporins.

    abstract::There are studies demonstrating that skin-test sensitivity to penicillins can decrease over time and that allergic patients may lose sensitivity if the responsible compounds are avoided. With regard to subjects with IgE-mediated hypersensitivity to cephalosporins, however, such studies are lacking. We evaluated prospe...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12390

    authors: Romano A,Gaeta F,Valluzzi RL,Zaffiro A,Caruso C,Quaratino D

    更新日期:2014-06-01 00:00:00

  • MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation.

    abstract::Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient empowerment. MASK-rh...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/all.12686

    authors: Bousquet J,Schunemann HJ,Fonseca J,Samolinski B,Bachert C,Canonica GW,Casale T,Cruz AA,Demoly P,Hellings P,Valiulis A,Wickman M,Zuberbier T,Bosnic-Anticevitch S,Bedbrook A,Bergmann KC,Caimmi D,Dahl R,Fokkens WJ,Gris

    更新日期:2015-11-01 00:00:00

  • Epicutaneous aeroallergen sensitization in atopic dermatitis infants - determining the role of epidermal barrier impairment.

    abstract:BACKGROUND:Sensitization to atopens is an early phenomenon that overlaps with the onset of atopic dermatitis (AD) in infancy. Early epidermal barrier impairment may facilitate the epicutaneous penetration of atopens. OBJECTIVE:To correlate transepidermal water loss (TEWL) and aeroallergen sensitization in infants with...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2007.01556.x

    authors: Boralevi F,Hubiche T,Léauté-Labrèze C,Saubusse E,Fayon M,Roul S,Maurice-Tison S,Taïeb A

    更新日期:2008-02-01 00:00:00

  • The quantity and quality of α-gal-specific antibodies differ in individuals with and without delayed red meat allergy.

    abstract:BACKGROUND:IgG to galactose-α-1,3-galactose (α-gal) are highly abundant natural antibodies (Ab) in humans. α-Gal-specific IgE Ab cause a special form of meat allergy characterized by severe systemic reactions 3-7 h after consumption of red meat. We investigated 20 patients who experienced such reactions and characteriz...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12948

    authors: Kollmann D,Nagl B,Ebner C,Emminger W,Wöhrl S,Kitzmüller C,Vrtala S,Mangold A,Ankersmit HJ,Bohle B

    更新日期:2017-02-01 00:00:00

  • Cord blood Tregs with stable FOXP3 expression are influenced by prenatal environment and associated with atopic dermatitis at the age of one year.

    abstract:BACKGROUND:Regulatory T cells (Tregs) with stable FOXP3 expression are characterized by a specific demethylated region in the FOXP3 gene (Treg-specific demethylated region, TSDR). The aim of this study was to analyse the influence of prenatal factors on cord blood Treg numbers, as detected by changes in the TSDR demeth...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2011.02767.x

    authors: Hinz D,Bauer M,Röder S,Olek S,Huehn J,Sack U,Borte M,Simon JC,Lehmann I,Herberth G,LINA study group.

    更新日期:2012-03-01 00:00:00

  • Association of control and risk of severe asthma-related events in severe or difficult-to-treat asthma patients.

    abstract:BACKGROUND:Clinical tools for predicting poor outcomes in asthma patients are lacking. This study investigated the association of asthma control and subsequent severe asthma-related healthcare events in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. METHODS:The extent of...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2007.01383.x

    authors: Sullivan SD,Wenzel SE,Bresnahan BW,Zheng B,Lee JH,Pritchard M,Kamath TV,Weiss ST,TENOR Study Group.

    更新日期:2007-06-01 00:00:00

  • Differential pattern of CCR1 internalization in human eosinophils: prolonged internalization by CCL5 in contrast to CCL3.

    abstract:BACKGROUND:Whereas recent studies underlie the fundamental importance of the CC chemokine receptor 3 (CCR3) for the recruitment of eosinophils in allergic diseases, controversial data exist about the relevance of CCR1 on eosinophils. Therefore, the purpose of this study was to investigate the expression and regulation ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2005.00893.x

    authors: Elsner J,Dulkys Y,Gupta S,Escher SE,Forssmann WG,Kapp A,Forssmann U

    更新日期:2005-11-01 00:00:00

  • CD40 and OX40 ligand are differentially regulated on asthmatic airway smooth muscle.

    abstract:BACKGROUND:CD40 and OX40 Ligand (OX40L) are cell-surface molecules expressed on airway smooth muscle (ASM) that can enhance inflammatory cell activation and survival. The aim of this study was to examine the effect of tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on ASM CD40 and OX40L expres...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2009.01959.x

    authors: Krimmer DI,Loseli M,Hughes JM,Oliver BG,Moir LM,Hunt NH,Black JL,Burgess JK

    更新日期:2009-07-01 00:00:00