Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients.

abstract：:Gastroesophageal reflux disease (GERD) occurs in up to one-third of the adult US population. Most affected individuals are either unaware of their condition or do not seek medical help, relying on nonprescription acid suppressants and antacids for relief. GERD, a common disorder of infancy, old age, and pregnancy, is ...

journal_title：Allergy

authors： Theodoropoulos DS,Lockey RF,Boyce HW Jr,Bukantz SC

更新日期：1999-07-01 00:00:00

abstract：:The phenotypes and receptors of the intraepithelial lymphocytes which are a major component of the mucosal immune system are of considerable interest. Intraepithelial lymphocytes, especially those of the intestines, are well documented. The nasal intraepithelial lymphocytes probably play a key role in the immune defen...

journal_title：Allergy

authors： Pawankar R,Okuda M

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Allergic asthma is associated with airway inflammation and dysfunction of pulmonary surfactant. Because surfactant proteins (SP) account for immunomodulatory functions as well as biophysical functions, we hypothesized that the allergic response in asthma might be accompanied by a dysregulation of SPs. METHO...

journal_title：Allergy

authors： Erpenbeck VJ,Schmidt R,Günther A,Krug N,Hohlfeld JM

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Over 100 million people worldwide suffer from birch pollen allergy. Bet v 1 has been identified as the major birch pollen allergen. However, the molecular mechanisms of birch allergic sensitization, including the roles of Bet v 1 and other components of the birch pollen extract, remain incompletely understoo...

journal_title：Allergy

authors： Soh WT,Aglas L,Mueller GA,Gilles S,Weiss R,Scheiblhofer S,Huber S,Scheidt T,Thompson PM,Briza P,London RE,Traidl-Hoffmann C,Cabrele C,Brandstetter H,Ferreira F

更新日期：2019-12-01 00:00:00

abstract：:The connective tissue disorders (also called collagen vascular diseases) represent an heterogeneous group of immunologically mediated inflammatory disorders with a large variety of affected organs besides the lungs. The respiratory system may be involved in all its components: airways, vessels, parenchyma, pleura, res...

journal_title：Allergy

authors： Crestani B

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The reported association of allergy and sinusitis varies greatly between study, and the exact role of allergy in predisposing to sinusitis is not clear. We attempted to determine whether patients with perennial allergic rhinitis are at greater risk of developing sinusitis with respect to a control group, and...

journal_title：Allergy

authors： Berrettini S,Carabelli A,Sellari-Franceschini S,Bruschini L,Abruzzese A,Quartieri F,Sconosciuto F

更新日期：1999-03-01 00:00:00

abstract：:A study was undertaken to see whether the principal airborne fungi in the North-East Netherlands were also found to be the most reactive in skin testing. Atmospheric samples were taken weekly with the Andersen sampler, from April 1981, up to and including, June 1983. At the same time skin tests of 833 patients referre...

journal_title：Allergy

authors： Beaumont F,Kauffman HF,de Monchy JG,Sluiter HJ,de Vries K

更新日期：1985-04-01 00:00:00

abstract：:A shared approach to decision-making framework has been suggested for chronic disease management especially where multiple treatment options exist. Shared decision-making (SDM) requires that both physician and patients are actively engaged in the decision-making process, including information exchange; expressing trea...

journal_title：Allergy

authors： Pollard S,Bansback N,FitzGerld JM,Bryan S

更新日期：2017-05-01 00:00:00

abstract：:Sera from 425 patients were analysed with Phadebas RAST reagents against a panel of 19 allergens and the most commonly positive results were to grass pollen, Dermatophagoides pteronyssinus and cat epithelium. Of the 275 sera RAST-positive to any allergen, 261 were positive by a RAST technique which used a mixture of t...

journal_title：Allergy

authors： Merrett TG,Pantin CF,Dimond AH,Merrett J

更新日期：1980-09-01 00:00:00

abstract：:Atopic dermatitis (AD) is a common inflammatory skin condition that has traditionally been considered a paradigmatic type 2 immunity (T2)-driven disease. Interleukin (IL)-4 and IL-13 are both pivotal cytokines involved in the generation of allergic diseases. Currently, besides dupilumab, which blocks the binding of bo...

journal_title：Allergy

authors： Bieber T

更新日期：2020-01-01 00:00:00

abstract：:Although mediators, such as lipids, cytokines, and chemokines, are related to the appearance of an IPR, there has been no reliable indicator to predict conditions for the appearance of an IPR. In this study, we adopted a proteomic approach to investigate the pathogenesis at the level of the plasma proteins and to deve...

journal_title：Allergy

authors： Rhim T,Choi YS,Nam BY,Uh ST,Park JS,Kim YH,Paik YK,Park CS

更新日期：2009-01-01 00:00:00

abstract：:Airway remodeling is a central feature of asthma. It is exemplified by thickening of the lamina reticularis and structural changes to the epithelium, submucosa, smooth muscle, and vasculature of the airway wall. Airway remodeling may result from persistent airway inflammation. Immunoglobulin E (IgE) is an important me...

journal_title：Allergy

authors： Rabe KF,Calhoun WJ,Smith N,Jimenez P

更新日期：2011-09-01 00:00:00

abstract：:Histamine is the primary mediator involved the pathophysiology of allergic rhinitis and chronic urticaria, and this explains the prominent role that histamine H(1)-receptor antagonists have in the treatment of these disorders. However, histamine is clearly not the only mediator involved in the inflammatory cascade. Th...

journal_title：Allergy

authors： Mullol J,Bousquet J,Bachert C,Canonica WG,Gimenez-Arnau A,Kowalski ML,Martí-Guadaño E,Maurer M,Picado C,Scadding G,Van Cauwenberge P

更新日期：2008-04-01 00:00:00

abstract：:: The use of specific immunotherapy (SIT) for allergic disorders has recently been extended by introduction of a convenient, tablet-based, disease-modifying vaccine against grass pollen allergy. Allergy immunotherapy tablet (AIT) programmes targeting house dust mite and other allergies are currently in late-phase deve...

journal_title：Allergy

authors： Sørensen P

更新日期：2011-07-01 00:00:00

abstract：:The objective was to present a case of periodic fever with aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), summarize the medical literature on PFAPA, review the differential diagnosis and suggest a diagnostic approach to periodic fevers in children. A PubMed search was conducted for all case reports an...

journal_title：Allergy

authors： Lierl M

更新日期：2007-12-01 00:00:00

abstract：:There is now extensive evidence that asthma results from inflammation in large and small airways, and that the degree of inflammation reflects the clinical severity of the disease. Most of this evidence, however, has come from studies in adult patients. Evidence in children comes largely from indirect studies such as ...

journal_title：Allergy

authors： van Aalderen WM,Sprikkelman AB,Hoekstra MO

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:IgE is the central antibody isotype in TH2-biased immunity and allergic diseases. The structure of intact IgE and the impact of IgE-targeting molecules on IgE however remain elusive. In order to obtain insights into IgE biology and the clinical impact, we aimed for structure determination of IgE and the comp...

journal_title：Allergy

authors： Jensen RK,Jabs F,Miehe M,Mølgaard B,Pfützner W,Möbs C,Spillner E,Andersen GR

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The association between cigarette smoke exposure and allergic airway disease is a matter for debate. We sought to investigate in an in vitro system whether active smoking reduces the integrity and barrier function of the respiratory epithelium and thus facilitates allergen penetration. METHODS:We cultured t...

journal_title：Allergy

authors： Gangl K,Reininger R,Bernhard D,Campana R,Pree I,Reisinger J,Kneidinger M,Kundi M,Dolznig H,Thurnher D,Valent P,Chen KW,Vrtala S,Spitzauer S,Valenta R,Niederberger V

更新日期：2009-03-01 00:00:00

abstract：:In order to determine the asthma prevalence in 6-12-year-old schoolchildren in Istanbul, we issued 2350 questionnaires, according to ISAAC criteria, in six randomly selected city primary schools to be completed at home by parents. A total of 2232 of the questionnaires were completed, an overall response rate of 94.9%,...

journal_title：Allergy

authors： Oneş U,Sapan N,Somer A,Dişçi R,Salman N,Güler N,Yalçin I

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Allergic diseases have become a major public health problem in developed countries; yet, no reliable, safe and consistently effective treatment is available. DNA immunization has been shown to prevent and balance established allergic responses, however, the high dose of conventional DNA vaccines necessary fo...

journal_title：Allergy

authors： Scheiblhofer S,Gabler M,Leitner WW,Bauer R,Zoegg T,Ferreira F,Thalhamer J,Weiss R

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The beta-lactam allergic work-up is mostly standardized. However, the negative predictive value of drug provocation tests is not yet well established. METHOD:A historical-prospective multicentre cohort study was conducted in four centres (one in France, one in Portugal, two in Italy) to assess the negative ...

journal_title：Allergy

authors： Demoly P,Romano A,Botelho C,Bousquet-Rouanet L,Gaeta F,Silva R,Rumi G,Rodrigues Cernadas J,Bousquet PJ

更新日期：2010-03-01 00:00:00

abstract：:Allergy to storage mites has been shown among farmers and grain elevator workers. This study aimed to examine whether bakers also are sensitized to storage mites. Twenty-three bakers or other employees in bakeries suffering from nasal or pulmonary symptoms were compared with 17 control persons with no relation to bake...

journal_title：Allergy

authors： Revsbech P,Dueholm M

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Food allergy may present with a plethora of gastrointestinal and extraintestinal symptoms such as abdominal pain, diarrhea, cardiocirculatory symptoms, cutaneous reactions, or rhinitis. Macropathological lesions like lymphofollicular hyperplasia and erosive or ulcerative lesions have seldom been described in...

journal_title：Allergy

authors： Hagel AF,de Rossi TM,Zopf Y,Lindner AS,Dauth W,Neurath MF,Raithel M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is an inflammatory process in the nasal cavity and paranasal sinuses, and bacteria have been considered to be a cause. Indeed, recent evidence indicates that bacteria-derived extracellular vesicles (EV) appear to be an important causative agent of inflammatory diseases. Here, we ...

journal_title：Allergy

authors： Choi EB,Hong SW,Kim DK,Jeon SG,Kim KR,Cho SH,Gho YS,Jee YK,Kim YK

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Allergic sensitisation increases the risk for asthma development. In this prospective birth cohort (Environment and Childhood Asthma) study, we hypothesized that combining quantitative measures of IgE antibodies (Sigma-IgE) and Severity score of obstructive airways disease (OAD) at 2 years of age (Severity s...

journal_title：Allergy

authors： Lødrup Carlsen KC,Söderström L,Mowinckel P,Håland G,Pettersen M,Munthe Kaas MC,Devulapalli CS,Buchmann M,Ahlstedt S,Carlsen KH

更新日期：2010-09-01 00:00:00

abstract：:Although studies of families, inbred populations and twins have established that asthma has a hereditary basis, little evidence has shown that intrinsic asthma has an increased familial occurrence. To document this issue, we compared the prevalence of asthma in families of intrinsic asthmatics, extrinsic asthmatics an...

journal_title：Allergy

authors： Pirson F,Charpin D,Sansonetti M,Lanteaume A,Kulling G,Charpin J,Vervloet D

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Skin biopsies promote our understanding of atopic dermatitis/AD pathomechanisms in infants/toddlers with early-onset AD, but are not feasible in pediatric populations. Tape strips are an emerging, minimally invasive alternative, but global transcriptomic profiling in early pediatric AD is lacking. We aimed t...

journal_title：Allergy

authors： Pavel AB,Renert-Yuval Y,Wu J,Del Duca E,Diaz A,Lefferdink R,Fang MM,Canter T,Rangel SM,Zhang N,Krueger JG,Paller AS,Guttman-Yassky E

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Analyses of exhaled volatile organic compounds (VOCs) have shown promising results when distinguishing individuals with asthma. Currently, there are no biomarkers for uncontrolled asthma. Therefore, we aimed to assess, in a real-life clinical setting, the ability of the exhaled VOC analysis, using an electro...

journal_title：Allergy

authors： Farraia M,Cavaleiro Rufo J,Paciência I,Castro Mendes F,Rodolfo A,Rama T,Rocha SM,Delgado L,Brinkman P,Moreira A

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The hygiene hypothesis proposes that reduced exposure to infectious agents in early life would explain the increase of allergic and autoimmune diseases observed over the past decades in high-income countries. METHODS:We conducted a matched case-control study on incident atopic dermatitis (AD). Cases were 42...

journal_title：Allergy

authors： Chatenoud L,Bertuccio P,Turati F,Galeone C,Naldi L,Chatenoud L,La Vecchia C,Bach JF,HYGIENE Study Group.

更新日期：2020-01-01 00:00:00

abstract：:During the last few years, an impressive amount of experimental studies and clinical trials have dealt with a variety of distinct topics in allergic skin diseases - especially atopic dermatitis. In this update, we discuss selected recent data that provide relevant insights into clinical and pathophysiological aspects ...

journal_title：Allergy

authors： Wollenberg A,Feichtner K

更新日期：2013-12-01 00:00:00