Antiproliferative effect of the somatostatin analogue octreotide on growth hormone-producing pituitary tumors: results of a multicenter randomized trial.

abstract：OBJECTIVE:To determine whether N-acetylcysteine rinse was safe and could improve thickened secretions and dry mouth during and after radiotherapy. PATIENTS AND METHODS:We designed a prospective pilot double-blind, placebo-controlled randomized clinical trial (Alliance MC13C2). Adult patients (age ≥18 years) were enrol...

journal_title：Mayo Clinic proceedings

authors： Sio TT,Blanchard MJ,Novotny PJ,Patel SH,Rwigema JM,Pederson LD,McGee LA,Gamez ME,Seeger GR,Martenson JA,Grover Y,Neben Wittich MA,Garces YI,Foote RL,Miller RC,Halyard MY

更新日期：2019-09-01 00:00:00

abstract：:The introduction of transesophageal echocardiography has provided a new acoustic window to the heart and mediastinum. High-quality images of certain cardiovascular structures [left atrial appendage, thoracic aorta, mitral valvular apparatus, and atrial septum] can be obtained readily (average examination, 15 to 20 min...

journal_title：Mayo Clinic proceedings

authors： Seward JB,Khandheria BK,Oh JK,Abel MD,Hughes RW Jr,Edwards WD,Nichols BA,Freeman WK,Tajik AJ

更新日期：1988-07-01 00:00:00

abstract：:The first generation of multicenter randomized controlled trials of coronary artery bypass surgery vs medical treatment in the 1970s found survival advantage only in patients with left main coronary artery disease or with multiple risk factors. Over time, these results have remained reproducible and biologically plaus...

journal_title：Mayo Clinic proceedings

authors： Detre KM,Holubkov R

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To assess whether dietary supplements that are herbal and/or animal-derived products, marketed for enhancing metabolism or promoting energy, "adrenal fatigue," or "adrenal support," contain thyroid or steroid hormones. METHODS:Twelve dietary adrenal support supplements were purchased. Pregnenolone, androsten...

journal_title：Mayo Clinic proceedings

authors： Akturk HK,Chindris AM,Hines JM,Singh RJ,Bernet VJ

更新日期：2018-03-01 00:00:00

abstract：:Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author. ...

journal_title：Mayo Clinic proceedings

authors： Wentz MR

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:To determine the long-term outcome of patients presenting with synchronous lymphoma and severe liver dysfunction and to describe the outcome of patients treated with initial mechlorethamine-based therapy used as a bridge to more conventional chemotherapy. PATIENTS AND METHODS:We reviewed the clinical course...

journal_title：Mayo Clinic proceedings

authors： Ghobrial IM,Wolf RC,Pereira DL,Fonseca R,White WL,Colgan JP,Habermann TM,Inwards DJ,Markovic SN,Ansell SM,Micallef IN,Porrata LF,Witzig TE

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To assess the impact of direct-to-consumer (DTC) predictive genomic risk information on perceived risk and worry in the context of routine clinical care. PATIENTS AND METHODS:Patients attending a preventive medicine clinic between June 1 and December 18, 2009, were randomly assigned to receive either genomic...

journal_title：Mayo Clinic proceedings

authors： James KM,Cowl CT,Tilburt JC,Sinicrope PS,Robinson ME,Frimannsdottir KR,Tiedje K,Koenig BA

更新日期：2011-10-01 00:00:00

abstract：:At the Mayo Clinic from 1962 through 1973, 592 cesarean sections were done among 16,181 deliveries (3.7%); 48% were primary procedures, and 52% were performed because of previous cesarean delivery. Regional anesthesia using epidural block recently has replaced a balanced general anesthesia as the anesthesia of choice...

journal_title：Mayo Clinic proceedings

authors： Aard LA,Saed F

更新日期：1975-07-01 00:00:00

abstract：:THE purpose of this study was to determine the difference in prognosis among patients with transient ischemic attacks (TIA) in the carotid arterial system and those with TIA in the vertebral-basilar arterial system. Nearly twice as many patients had TIA in the carotid system as had TIA in the vertebral-basilar system....

journal_title：Mayo Clinic proceedings

authors： Cartlidge NE,Whisnant JP,Elveback LR

更新日期：1977-02-01 00:00:00

abstract：OBJECTIVE:To assess the reliability, durability, and safety of primary and revision total hip arthroplasty (THA) in patients 90 years of age and older. PATIENTS AND METHODS:Between 1970 and 1997, 66 THAs, 48 primary and 18 revision, were done for 65 patients aged 90 to 104 years (mean, 92 years). The Harris hip score ...

journal_title：Mayo Clinic proceedings

authors： Pagnano MW,McLamb LA,Trousdale RT

更新日期：2003-03-01 00:00:00

abstract：:Coronary artery fistulas are infrequently encountered vascular communications that are either congenital or due to cardiac trauma. Most patients with these anomalies are asymptomatic, but late complications can occur and include congestive heart failure, myocardial ischemia, arrhythmias, and endocarditis. Therefore, m...

journal_title：Mayo Clinic proceedings

authors： Harris WO,Andrews JC,Nichols DA,Holmes DR Jr

更新日期：1996-01-01 00:00:00

abstract：:Extending a study of the period 1935-1964, we determined the incidence rates of leukemia in Olmsted County during the decade 1965-1974. In this decade, the overall crude annual incidence rate was 9.5 per 100,000. The ratio of males to females was 2.4 to 1; and the incidence rate was significantly higher among males th...

journal_title：Mayo Clinic proceedings

authors： Linos A,Kyle RA,Elveback LR,Kurland LT

更新日期：1978-11-01 00:00:00

abstract：:From 1974 through 1982, fulminant hepatitis was diagnosed in 34 patients at our institution. Of these patients, only two survived (survival rate, 6%). This syndrome was caused by viruses (B and non-B hepatitis and herpes simplex) in 23 patients, hepatotoxic drug in 6, Wilson's disease (hepatolenticular degeneration) i...

journal_title：Mayo Clinic proceedings

authors： Rakela J,Lange SM,Ludwig J,Baldus WP

更新日期：1985-05-01 00:00:00

abstract：:In August 2015, an expert colloquium commissioned by the Sexual Medicine Society of North America (SMSNA) convened in Washington, DC, to discuss the common clinical scenario of men who present with low testosterone (T) and associated signs and symptoms accompanied by low or normal gonadotropin levels. This syndrome is...

journal_title：Mayo Clinic proceedings

authors： Khera M,Broderick GA,Carson CC 3rd,Dobs AS,Faraday MM,Goldstein I,Hakim LS,Hellstrom WJ,Kacker R,Köhler TS,Mills JN,Miner M,Sadeghi-Nejad H,Seftel AD,Sharlip ID,Winters SJ,Burnett AL

更新日期：2016-07-01 00:00:00

abstract：:Hip arthroplasty using the Thompson femoral prosthesis with methyl methacrylate fixation was performed on 109 hips in 106 patients. During an average follow-up period of 36 months, 26 patients died. Fifty-one procedures were performed for fresh fractures of the femoral neck and results were satisfactory in this group ...

journal_title：Mayo Clinic proceedings

authors： Beckenbaugh RD,Tressler HA,Johnson EW Jr

更新日期：1977-06-01 00:00:00

abstract：:Evidence suggests that migraine is associated with decreased productivity. This article describes the results of a systematic literature review of peer-reviewed publications that measured the impact of migraine on workplace productivity in the United States and provides recommendations for future research. A MEDLINE s...

journal_title：Mayo Clinic proceedings

authors： Burton WN,Landy SH,Downs KE,Runken MC

更新日期：2009-05-01 00:00:00

abstract：:The Human Genome Project has resulted in a new era in the field of pharmacogenetics in which researchers are rapidly discovering new genetic variation, which may help to explain interindividual variability in drug efficacy and toxicity. Pharmacogenetics is the study of the role of genetic inheritance in individual var...

journal_title：Mayo Clinic proceedings

authors： Goetz MP,Ames MM,Weinshilboum RM

更新日期：2004-03-01 00:00:00

abstract：:Total respiratory resistance (Rrs) was studied by the forced oscillation technique at a frequency of 3 cps in 76 normal subjects (36 men, 40 women), ages 21 to 64 years. Slopes (equivalent to specific conductance) assuming a linear relationship with zero intercept between 1/Rrs and thoracic gas volume (TGV) were compu...

journal_title：Mayo Clinic proceedings

authors： Jiemsripong K,Hyatt RE,Offord KP

更新日期：1976-09-01 00:00:00

abstract：OBJECTIVE:To investigate the association between physical activity (PA) and risk of mortality in a large middle-aged cohort stratified by inflammatory status. PATIENTS AND METHODS:A total of 336,560 individuals (mean age, 39.7 years; 58% male) who underwent comprehensive health screenings were enrolled in this prospec...

journal_title：Mayo Clinic proceedings

authors： Lee JY,Ryu S,Cheong E,Sung KC

更新日期：2016-12-01 00:00:00

abstract：:Hepatitis C virus infection is common, often silent, and almost always chronic and can lead to cirrhosis and hepatocellular cancer. Deaths related to chronic hepatitis C are expected to increase dramatically in the future. Many cases of infection are asymptomatic and are undiagnosed because of a lack of recognition by...

journal_title：Mayo Clinic proceedings

authors： Gross JB Jr

更新日期：1998-04-01 00:00:00

abstract：:We developed and validated a radioimmunoassay for circulating human parathyroid hormone-related peptide (PTHrP), based on a commercial antiserum to the synthetic 1-34 fragment of PTHrP, 125I-Tyr degrees-PTHrP(1-34) as radioligand, and prior extraction of the native peptide from plasma with C-2 cartridges. We determine...

journal_title：Mayo Clinic proceedings

authors： Kao PC,Klee GG,Taylor RL,Heath H 3rd

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:To analyze the influence of recent changes in Minnesota statutes that generally require prior authorization for use of medical records for research from patients who received medical care after Jan. 1, 1997. MATERIAL AND METHODS:In this Mayo Clinic Institutional Review Board-approved study, we obtained a str...

journal_title：Mayo Clinic proceedings

authors： Jacobsen SJ,Xia Z,Campion ME,Darby CH,Plevak MF,Seltman KD,Melton LJ 3rd

更新日期：1999-04-01 00:00:00

abstract：:The clinical and morphologic findings of allergic granulomatosis and angiitis of Churg and Strauss in 21 men and 9 women were reviewed. The classic features are those of systemic vasculitis in a setting of bronchial asthma and eosinophilia. Pathologically there is necrotizing vasculitis of small arteries and veins wit...

journal_title：Mayo Clinic proceedings

authors： Chumbley LC,Harrison EG Jr,DeRemee RA

更新日期：1977-08-01 00:00:00

abstract：:Penile squamous cell carcinoma (PSCC) is a rare cancer, with approximately 2000 new cases in the United States and 35,000 globally every year. Multiple risk factors are involved in PSCC, but most importantly, the high-risk human papillomavirus infection is thought to be present in approximately 50% of cases. Penile sq...

journal_title：Mayo Clinic proceedings

authors： Chahoud J,Kohli M,Spiess PE

更新日期：2020-12-08 00:00:00

abstract：OBJECTIVE:To estimate the age- and sex-adjusted incidence of melanoma in adults 61 years or older in Olmsted County, Minnesota, from 1970 through 2009. PATIENTS AND METHODS:Using Rochester Epidemiology Project resources, 397 patients were identified who were 61 years or older and who received a first lifetime diagnosi...

journal_title：Mayo Clinic proceedings

authors： Olazagasti Lourido JM,Ma JE,Lohse CM,Brewer JD

更新日期：2016-11-01 00:00:00

abstract：:The increasing prevalence and far-reaching medical, social, and economical implications of obesity have made it a national health-care crisis in the United States. About one in every three persons is at least 20% above "ideal" body weight, and approximately 5% have direct weight-related serious health problems (morbid...

journal_title：Mayo Clinic proceedings

authors： Balsiger BM,Luque de Leon E,Sarr MG

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:To measure carotid artery intima-media thickness (CIMT), a marker of subclinical atherosclerosis, in postmenopausal women with and without histories of preeclampsia and to synthesize these results with those from prior studies of CIMT performed 10 or more years after preeclamptic pregnancies. PATIENTS AND ME...

journal_title：Mayo Clinic proceedings

authors： Garovic VD,Milic NM,Weissgerber TL,Mielke MM,Bailey KR,Lahr B,Jayachandran M,White WM,Hodis HN,Miller VM

更新日期：2017-09-01 00:00:00

abstract：:The treatment of chronic illnesses commonly includes the long-term use of pharmacotherapy. Although these medications are effective in combating disease, their full benefits are often not realized because approximately 50% of patients do not take their medications as prescribed. Factors contributing to poor medication...

journal_title：Mayo Clinic proceedings

authors： Brown MT,Bussell JK

更新日期：2011-04-01 00:00:00

abstract：:Two patients had both scleroderma and a columnar epithelium-lined lower esophagus (Barrett esophagus). Features of Barrett's esophagus included high esophageal strictures in both patients and ulcer craters in the columnar area of one. Biopsy confirmed columnar epithelium in the lower esophagus of each patient. In thes...

journal_title：Mayo Clinic proceedings

authors： Cameron AJ,Payne WS

更新日期：1978-09-01 00:00:00

abstract：:Endoscopic esophageal variceal sclerotherapy (EVS) is often used in the treatment of upper gastrointestinal hemorrhage due to esophageal varices. We retrospectively reviewed the Mayo Clinic experience with EVS between 1980 and 1989 to determine the incidence of thoracic manifestations and chest roentgenographic abnorm...

journal_title：Mayo Clinic proceedings

authors： Zeller FA,Cannan CR,Prakash UB

更新日期：1991-07-01 00:00:00