Adult-Onset Hypogonadism.

Abstract:

:In August 2015, an expert colloquium commissioned by the Sexual Medicine Society of North America (SMSNA) convened in Washington, DC, to discuss the common clinical scenario of men who present with low testosterone (T) and associated signs and symptoms accompanied by low or normal gonadotropin levels. This syndrome is not classical primary (testicular failure) or secondary (pituitary or hypothalamic failure) hypogonadism because it may have elements of both presentations. The panel designated this syndrome adult-onset hypogonadism (AOH) because it occurs commonly in middle-age and older men. The SMSNA is a not-for-profit society established in 1994 to promote, encourage, and support the highest standards of practice, research, education, and ethics in the study of human sexual function and dysfunction. The panel consisted of 17 experts in men's health, sexual medicine, urology, endocrinology, and methodology. Participants declared potential conflicts of interest and were SMSNA members and nonmembers. The panel deliberated regarding a diagnostic process to document signs and symptoms of AOH, the rationale for T therapy, and a monitoring protocol for T-treated patients. The evaluation and management of hypogonadal syndromes have been addressed in recent publications (ie, the Endocrine Society, the American Urological Association, and the International Society for Sexual Medicine). The primary purpose of this document was to support health care professionals in the development of a deeper understanding of AOH, particularly in how it differs from classical primary and secondary hypogonadism, and to provide a conceptual framework to guide its diagnosis, treatment, and follow-up.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Khera M,Broderick GA,Carson CC 3rd,Dobs AS,Faraday MM,Goldstein I,Hakim LS,Hellstrom WJ,Kacker R,Köhler TS,Mills JN,Miner M,Sadeghi-Nejad H,Seftel AD,Sharlip ID,Winters SJ,Burnett AL

doi

10.1016/j.mayocp.2016.04.022

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

908-26

issue

7

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(16)30143-4

journal_volume

91

pub_type

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