Abstract：
:Cirrhosis and its disease-related complications are the 12th leading cause of mortality among U.S. adults and are the 5th leading cause of death for individuals aged 45 to 54 years. Hospitalization costs for disease-related complications are estimated at 18,000 dollars per episode of care, and 10% of admitted patients die. Despite these ominous findings, the survival rate of patients with cirrhosis has improved during the past 2 decades. This observation coincides with the conducting and reporting of high-quality randomized controlled trials and observational studies. Therefore, the improved prognosis in cirrhosis may be related to the effective translation of research findings to clinical practice for this patient population. Although explicit data to support this claim are not available, this article reviews the reported trends in clinical outcomes for patients with cirrhosis and the existence of evidence-based medical information that is available to care for these chronically ill patients.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Talwalkar JA,Kamath PSdoi
10.4065/80.11.1501keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
1501-8issue
11eissn
0025-6196issn
1942-5546pii
S0025-6196(11)61444-4journal_volume
80pub_type
杂志文章,评审abstract：OBJECTIVE:To assess whether dietary supplements that are herbal and/or animal-derived products, marketed for enhancing metabolism or promoting energy, "adrenal fatigue," or "adrenal support," contain thyroid or steroid hormones. METHODS:Twelve dietary adrenal support supplements were purchased. Pregnenolone, androsten...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2017.10.019
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:To investigate the incidence of bone disorders after solid organ transplantation (SOT). PARTICIPANTS AND METHODS:We used Taiwan's National Health Insurance Research Database to identify 9428 recipients of SOT and 38,140 sex- and age- matched control subjects between January 1, 1997, and December 31, 2010, to...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2014.02.017
更新日期：2014-07-01 00:00:00
abstract：:Cataract operations are commonly performed in either a primary-care or a tertiary-care center. A plethora of information (some of which is unfounded) has been disseminated in the lay news media about the advances in the surgical techniques of cataract removal. This article reviews some of the recent concepts about the...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)61494-3
更新日期：1984-08-01 00:00:00
abstract：OBJECTIVE:In this report, our goal was to summarize the current knowledge of the biochemical basis for the impaired DNA synthesis and neuropathy associated with vitamin B12 deficiency. MATERIAL AND METHODS:We reviewed the pertinent literature and our clinical experience with cobalamin deficiency. RESULTS:Studies have...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)61046-5
更新日期：1994-02-01 00:00:00
abstract：OBJECTIVE:To summarize results of telemedicine evaluations of speech and language disorders in patients in a small, rural hospital and in large multidisciplinary medical practices. MATERIALS AND METHODS:Eight patients underwent assessment as part of experiments with the National Aeronautics and Space Administration-la...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/72.12.1116
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the long-term prognostic effect of resting heart rate (HR) at index myocardial infarction (MI) and during the first year after MI among 1-year survivors. PATIENTS AND METHODS:The community-based cohort consisted of 1571 patients hospitalized with an incident MI from January 1, 1983, through Decem...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2014.07.017
更新日期：2014-12-01 00:00:00
abstract：:Use of amiodarone, an investigational antidysrhythmic agent, has been associated with cases of pulmonary toxicity. The mechanism of amiodarone pulmonary toxicity is unknown, and recommendations for the assessment and treatment of patients with this condition continue to evolve. In two patients with clinically diagnose...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)60983-5
更新日期：1985-09-01 00:00:00
abstract：OBJECTIVE:To identify and assess the impact of postoperative complications in patients with unrecognized or known obstructive sleep apnea syndrome (OSAS) undergoing hip replacement or knee replacement compared with control patients undergoing similar operations. Although OSAS is a risk factor for perioperative morbidit...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/76.9.897
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVE:To assess the effects of body mass index (BMI) variability on the incidence of new-onset atrial fibrillation (AF), stroke, cardiovascular (CV) risk factors, and CV outcomes in a general Asian population. PATIENTS AND METHODS:Data from the National Health Insurance Service-Health Screening cohort in Korea wer...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,多中心研究
doi：10.1016/j.mayocp.2018.10.019
更新日期：2019-02-01 00:00:00
abstract：:A careful clinical history and physical examination are the most important components of the preoperative assessment of the cardiac patient who is to undergo a noncardiac surgical procedure. From these factors and the nature of the surgical procedure planned, a reasonable estimate of potential cardiac risk can be form...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)64980-5
更新日期：1989-09-01 00:00:00
abstract：OBJECTIVE:To determine the risk of hospitalization and death in relation to preexisting depression and anxiety among patients with cardiovascular disease (CVD). PATIENTS AND METHODS:The cohort consisted of 799 Olmsted County, MN, residents diagnosed with CVD (myocardial infarction or heart failure) from January 1, 197...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/mcp.2011.0148
更新日期：2011-11-01 00:00:00
abstract：:The platelets of a patient with the Bernard-Soulier syndrome were studied by electron microscopy. The main abnormalities were the presence of giant and often round platelets, hypertrophic and frequently widely dilated open canalicular system, disorganized microtubules, and platelets with sparse or absent granulation....
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1975-07-01 00:00:00
abstract：OBJECTIVE:To assess the impact of direct-to-consumer (DTC) predictive genomic risk information on perceived risk and worry in the context of routine clinical care. PATIENTS AND METHODS:Patients attending a preventive medicine clinic between June 1 and December 18, 2009, were randomly assigned to receive either genomic...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,随机对照试验
doi：10.4065/mcp.2011.0190
更新日期：2011-10-01 00:00:00
abstract：:Chest pain in a young person is often caused by chest wall tenderness, associated with mitral valve prolapse, or attributed to psychologic factors. Ischemic cardiac pain may be overlooked because of its rare occurrence in this age group. A 35-year-old woman complained of substernal chest pressure precipitated by exert...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)64859-9
更新日期：1988-04-01 00:00:00
abstract：:In a group of 47 patients with mediastinal granulomas, the most common clinical symptoms were cough, chest pain, dysphagia, hemoptysis, and dyspnea. The main laboratory findings were right paratracheal or hilar mass on chest roentgenogram, positive histoplasmin skin test, and caseating granuloma on histopathologic exa...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1975-12-01 00:00:00
abstract：:Thirty-one patients with low back pain resistant to medical and surgical treatment were studied. On admission to the psychiatric service, these patients revealed apparent features of conversion and hysterical personality, as characterized also by the MMPI profile. During hospitalization, however, there was increased a...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:To identify the wishes of patients with amyotrophic lateral sclerosis (ALS) for information, participation in decision making, and life-sustaining therapy and to determine whether these wishes are stable over time, we conducted a prospective survey (baseline and 6-month follow-up interviews) of 38 consecutive patients...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)61577-8
更新日期：1991-09-01 00:00:00
abstract：OBJECTIVE:To determine whether dehydroepiandrosterone (DHEA) replacement therapy in hypoadrenal women improves performance, muscle protein accretion, and mitochondrial functions. PARTICIPANTS AND METHODS:Thirty-three hypoadrenal women were enrolled in the study from May 1, 2002, through May 31, 2003. Twenty-eight comp...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,随机对照试验
doi：10.4065/83.11.1218
更新日期：2008-11-01 00:00:00
abstract：:A 27-year-old man with a history of acne presented to his primary care physician because of fatigue and dyspnea on exertion of 4 weeks' duration. He was remarkably pale, orthostatic pulse changes were noted, and a systolic ejection murmur was heard. The patient had profound anemia (hemoglobin concentration, 5.0 g/dL) ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/77.7.713
更新日期：2002-07-01 00:00:00
abstract：OBJECTIVE:To explore the transcriptomic differences between patients with hypertrophic cardiomyopathy (HCM) and controls. PATIENTS AND METHODS:RNA was extracted from cardiac tissue flash frozen at therapeutic surgical septal myectomy for 106 patients with HCM and 39 healthy donor hearts. Expression profiling of 37,846...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2020.04.028
更新日期：2020-07-01 00:00:00
abstract：:The sport of snow skiing by the physically disabled, which originated in Europe in 1935 and first received attention in the United States in the 1940s, is reviewed in terms of opportunities available, instructions, adaptive equipment necessary, and benefits provided. Persons with a wide variety of disabilities (such a...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)60488-1
更新日期：1991-02-01 00:00:00
abstract：OBJECTIVE:To determine the effects of cardiac rehabilitation interventions on patients with hostility, or unexpressed anger, a coronary heart disease risk factor that adversely affects morbidity and mortality after major coronary heart disease events. METHODS:Using validated questionnaires to evaluate behavioral chara...
journal_title：Mayo Clinic proceedings
pub_type： 临床试验,杂志文章
doi：10.4065/74.10.959
更新日期：1999-10-01 00:00:00
abstract：:Between Jan. 1, 1976, and Dec. 31, 1985, at our institution, 37 patients who had undergone prior complete surgical resection of non-small-cell lung cancer received definitive thoracic radiation therapy (TRT) for locally recurrent disease. Of the 37 recurrences, 33 were in the pulmonary parenchyma or the hilar, mediast...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)61141-0
更新日期：1992-12-01 00:00:00
abstract：:Eighty-two consecutive orthopedic patients were assessed nutritionally at the time of hospital admission and then at 10-day intervals until hospital dismissal. Forty-eight percent of the patients had one or more abnormal findings suggestive of protein-calorie malnutrition. In spite of this prevalence of abnormal findi...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which presents an unprecedented challenge to medical providers worldwide. Although most SARS-CoV-2-infected individuals manifest with a self-limited mild disease that resolves with supportive care in the ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/j.mayocp.2020.05.010
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To describe the causes, evaluation, and management of urinary incontinence in the elderly population. DESIGN:We reviewed pertinent articles in the medical literature and summarized the types of incontinence and contributing factors. RESULTS:Urinary incontinence is common in elderly patients and often has a ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/71.1.93
更新日期：1996-01-01 00:00:00
abstract：:Effective antimicrobial therapy for most urinary tract infections has been available since the sulfonamide era. Innovations in chemotherapy now include single-dose treatment of acute bacterial cystitis and acute urethral syndrome and effective suppression of recurrent bacteriuria with low-dose antimicrobial agents. ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：:A 33-year-old woman with acute idiopathic postganglionic panautonomic neuropathy experienced prompt recovery of all dysautonomic symptoms after receiving high-dose intravenous immunoglobulin therapy. Her recovery was complete within 6 months after onset of disease. This unusually rapid and complete recovery in compari...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/72.4.333
更新日期：1997-04-01 00:00:00
abstract：OBJECTIVE:To assess the effects of glutathione on pain-free walking distance (PFWD) and hemodynamic parameters in patients with peripheral artery disease. PATIENTS AND METHODS:Forty patients with Fontaine stage II peripheral artery disease who were seen between September 2000 and March 2001 at the vascular laboratory ...
journal_title：Mayo Clinic proceedings
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.4065/77.8.754
更新日期：2002-08-01 00:00:00
abstract：:Extending a study of the period 1935-1964, we determined the incidence rates of leukemia in Olmsted County during the decade 1965-1974. In this decade, the overall crude annual incidence rate was 9.5 per 100,000. The ratio of males to females was 2.4 to 1; and the incidence rate was significantly higher among males th...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
