Abstract：
:The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which presents an unprecedented challenge to medical providers worldwide. Although most SARS-CoV-2-infected individuals manifest with a self-limited mild disease that resolves with supportive care in the outpatient setting, patients with moderate to severe COVID-19 will require a multidisciplinary collaborative management approach for optimal care in the hospital setting. Laboratory and radiologic studies provide critical information on disease severity, management options, and overall prognosis. Medical management is mostly supportive with antipyretics, hydration, oxygen supplementation, and other measures as dictated by clinical need. Among its medical complications is a characteristic proinflammatory cytokine storm often associated with end-organ dysfunction, including respiratory failure, liver and renal insufficiency, cardiac injury, and coagulopathy. Specific recommendations for the management of these medical complications are discussed. Despite the issuance of emergency use authorization for remdesivir, there are still no proven effective antiviral and immunomodulatory therapies, and their use in COVID-19 management should be guided by clinical trial protocols or treatment registries. The medical care of patients with COVID-19 extends beyond their hospitalization. Postdischarge follow-up and monitoring should be performed, preferably using telemedicine, until the patients have fully recovered from their illness and are released from home quarantine protocols.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Razonable RR,Pennington KM,Meehan AM,Wilson JW,Froemming AT,Bennett CE,Marshall AL,Virk A,Carmona EMdoi
10.1016/j.mayocp.2020.05.010subject
Has Abstractpub_date
2020-07-01 00:00:00pages
1467-1481issue
7eissn
0025-6196issn
1942-5546pii
S0025-6196(20)30515-2journal_volume
95pub_type
杂志文章,评审abstract：OBJECTIVE:To investigate the incidence and risk of adverse clinical outcomes in a "real-world" cohort of patients with atrial fibrillation (AF) anticoagulated with vitamin K antagonists (VKAs) from the Murcia AF Project in comparison with the warfarin arm of the randomized clinical trial (RCT) AMADEUS (Evaluating the U...
journal_title：Mayo Clinic proceedings
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abstract：:A series of 58 operations on 56 patients, in whom a branch of the superficial temporal artery was anastomosed to a branch of the middle cerebral artery (STA-MCA bypass or Yasargil procedure), is reviewed. These operations were performed chiefly for occlussions or for inaccessible stenotic lesions of the internal carot...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1976-11-01 00:00:00
abstract：:To our knowledge, edema of the lower extremities has not previously been reported as a sign of a pancreatic pseudocyst. In this case report, we describe a 66-year-old man in whom such a lesion compressed the inferior vena cava and caused pronounced leg swelling. After drainage of the pseudocyst, the edema did not recu...
journal_title：Mayo Clinic proceedings
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doi：10.1016/s0025-6196(12)61125-2
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journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1983-04-01 00:00:00
abstract：OBJECTIVE:To explore the influence of referral bias on complication rates after vaginal hysterectomy. PATIENTS AND METHODS:Community-based (local) and referral patients had benign indications and underwent vaginal hysterectomy from January 1, 2004, through December 31, 2005. We retrospectively evaluated patient charac...
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journal_title：Mayo Clinic proceedings
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pub_type： 杂志文章,评审
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journal_title：Mayo Clinic proceedings
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doi：10.4065/76.7.753
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journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/71.1.93
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journal_title：Mayo Clinic proceedings
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pub_type： 杂志文章,评审
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journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1977-11-01 00:00:00
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pub_type： 杂志文章
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journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,meta分析
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pub_type： 杂志文章,评审
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abstract：:Use of amiodarone, an investigational antidysrhythmic agent, has been associated with cases of pulmonary toxicity. The mechanism of amiodarone pulmonary toxicity is unknown, and recommendations for the assessment and treatment of patients with this condition continue to evolve. In two patients with clinically diagnose...
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