Abstract:
OBJECTIVE:To determine the effects of cardiac rehabilitation interventions on patients with hostility, or unexpressed anger, a coronary heart disease risk factor that adversely affects morbidity and mortality after major coronary heart disease events. METHODS:Using validated questionnaires to evaluate behavioral characteristics and quality of life, we studied 500 consecutive patients before and after cardiac rehabilitation and compared a group of 65 patients with high levels of hostility with 435 patients with low levels of hostility. RESULTS:After rehabilitation, statistically significant improvements occurred in the total cohort in scores for anxiety, depression, and somatization, as well as total quality of life, but not in hostility score (-20%; P = .07). Patients with high levels of hostility had significant improvements in hostility scores as well as other behavioral characteristics (anxiety, depression, and somatization) and all quality-of-life components. These patients also improved exercise capacity, percent body fat, body mass index, and total cholesterol and high-density lipoprotein cholesterol levels. Compared with patients with low levels of hostility, those with high levels of hostility had greater relative improvements in hostility scores, as well as anxiety, general health, energy, mental health, and total quality-of-life scores, and had similar improvements in exercise capacity, obesity indexes, lipid levels, and other behavioral characteristics and quality-of-life measurements. After cardiac rehabilitation, the prevalence of high levels of hostility decreased by 40%, from 13% to 8% (P < .01). CONCLUSIONS:These data suggest that cardiac rehabilitation reduces hostility and significantly improves quality of life and other behavioral characteristics in patients with high levels of hostility. We believe that greater attention should be directed at behavioral characteristics, including hostility, to enhance the primary and particularly the secondary prevention of coronary heart disease.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Lavie CJ,Milani RVdoi
10.4065/74.10.959keywords:
subject
Has Abstractpub_date
1999-10-01 00:00:00pages
959-66issue
10eissn
0025-6196issn
1942-5546pii
S0025-6196(11)63992-Xjournal_volume
74pub_type
临床试验,杂志文章abstract::Many types of psychotherapeutic drugs (especially antidepressants) directly and indirectly interact with neurotransmitter receptors, the recognition sites for the chemical messengers released by neurons. These interactions can result in increased or decreased sensitivity of certain receptors. Hypotheses exist to expla...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract::In this article, we describe an integrated approach for detection and evaluation of solitary pulmonary nodules. Initial evaluation of the solitary pulmonary nodule includes tomography, fluoroscopy, and comparison with previously obtained roentgenograms. Subsequently, thin-section computed tomography and phantom densit...
journal_title:Mayo Clinic proceedings
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journal_title:Mayo Clinic proceedings
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
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journal_title:Mayo Clinic proceedings
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1016/j.mayocp.2017.05.030
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journal_title:Mayo Clinic proceedings
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pub_type: 杂志文章,随机对照试验
doi:10.4065/mcp.2011.0190
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
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更新日期:2016-09-01 00:00:00
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
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journal_title:Mayo Clinic proceedings
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Mayo Clinic proceedings
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/S0025-6196(11)64844-1
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/mcp.2009.0511
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journal_title:Mayo Clinic proceedings
pub_type: 临床试验,杂志文章
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
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journal_title:Mayo Clinic proceedings
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journal_title:Mayo Clinic proceedings
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
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journal_title:Mayo Clinic proceedings
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doi:
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pub_type: 杂志文章
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