Abstract：
:The old paradigm states that the greater the stenosis, the greater the risk of cardiac events. Revascularization procedures are the only effective approach to improving prognosis associated with coronary artery disease. In contrast, on the basis of the new paradigm, the nature of the plaque determines the risk of acute cardiovascular events. Dangerous plaques have a lipid-rich core with surrounding inflammation and a thin friable overlying fibrous cap, but they usually appear innocuous on angiography. Effective risk factor modification stabilizes the dangerous plaques and is associated with prompt improvement in endothelial dysfunction and a substantial decrease in the risk of acute cardiovascular events and death.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
O'Keefe JH Jr,Conn RD,Lavie CJ,Bateman TMsubject
Has Abstractpub_date
1996-10-01 00:00:00pages
957-65issue
10eissn
0025-6196issn
1942-5546pii
S0025-6196(11)63769-5journal_volume
71pub_type
杂志文章,评审abstract：:Iatrogenic injury-injury caused unintentionally by medical treatment-breaks the oldest and most famous rule of medical ethics: primum non nocere, or above all, do no harm. Medical malpractice law, however, focuses on whether an injury was caused by negligence, not on whether an injury was iatrogenic. Iatrogenic injury...
journal_title：Mayo Clinic proceedings
pub_type： 传,历史文章,杂志文章,评审
doi：10.1016/j.mayocp.2014.05.004
更新日期：2014-09-01 00:00:00
abstract：:This discussion concerns an overview of our considerations of the adrenergic nervous system with respect to those areas of the nervous system that provide direct sensory input to the brain in control of arterial pressure; those brain centers that also participate in regulating arterial pressure; certain neurohumoral c...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：
更新日期：1977-06-01 00:00:00
abstract：OBJECTIVE:To determine the incidence and distribution of radical prostatectomy (RP) in the United States over time. PATIENTS AND METHODS:We conducted a serial cross-sectional analysis of time trends using the Nationwide Inpatient Sample of adult men older than 45 years who underwent RP between January 1, 1998, and Dec...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2015.09.018
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To assess whether caffeine intake is associated with all-cause and cause-specific mortality. PATIENTS AND METHODS:We conducted a prospective cohort study using data from the National Health and Nutrition Examination Survey 1999-2010. Cox proportional hazards models were used to compare the multivariate-adjus...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2017.03.010
更新日期：2017-08-01 00:00:00
abstract：:Between January 1973 and October 1991 at the Mayo Clinic, 5 of 345 patients with Wegener's granulomatosis initially had features suggestive of giant cell arteritis and subsequently were found to have biopsy-proven vasculitis of the temporal artery. All five patients were older than 60 years of age and had jaw claudica...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)60157-8
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVE:To determine the frequency of fetal urinary tract anomalies and to characterize the types of such abnormalities detected on ultrasonography and the outcome of affected patients during a 15-year period at our institution. DESIGN:We retrospectively reviewed the findings on maternal prenatal ultrasound examinat...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/70.6.526
更新日期：1995-06-01 00:00:00
abstract：:A 36-year-old man sought medical attention because of pressure in his head and distention of the veins in his neck. Physical examination disclosed a murmur of aortic insufficiency, and a chest roentgenogram showed a dilated ascending aorta. Two-dimensional echocardiography and angiography demonstrated a large intimal ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)65202-1
更新日期：1986-02-01 00:00:00
abstract：OBJECTIVE:To examine the ability of 4 published osteoporosis risk indices to identify women with low bone density. SUBJECTS AND METHODS:Subjects included postmenopausal women 45 years and older consecutively recruited from US clinics, women from general practice centers in The Netherlands (age range, 50-80 years), wom...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/77.7.629
更新日期：2002-07-01 00:00:00
abstract：:To many clinicians, the assessment of health-related quality of life (HRQL) seems more art than science. This belief is due in part to the lack of formal training available to clinicians regarding HRQL measurement and interpretation. When HRQL is used systematically, it has been shown to improve patient-physician comm...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/82.10.1244
更新日期：2007-10-01 00:00:00
abstract：OBJECTIVE:To determine the sensitivity and specificity of a quantitative plasma fibrin D-dimer latex immunoassay (LIA) for the diagnosis of acute pulmonary embolism. SUBJECTS AND METHODS:Study subjects were Mayo Clinic Rochester inpatients and outpatients with suspected acute pulmonary embolism; all had undergone quan...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/82.5.556
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVE:To describe the Mayo Clinic experience with emergency video telemedicine consultations for high-risk newborn deliveries. PATIENTS AND METHODS:From March 26, 2013, through December 31, 2015, the Division of Neonatal Medicine offered newborn telemedicine consultations to 6 health system sites. A wireless table...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2016.08.006
更新日期：2016-12-01 00:00:00
abstract：:In recent cases on the constitutionality of sentencing to death criminals who were younger than 18 years of age at the time of their crimes or who are mentally retarded, the US Supreme Court has rejected medical evidence that such persons categorically possess diminished culpability. Rather, the Court has accepted the...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)60023-8
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:To provide a practical formula for fresh frozen plasma (FFP) dosing for warfarin reversal. PATIENTS AND METHODS:We reviewed data on all adult patients who received a total of 7778 units of FFP for warfarin reversal at Sentara Norfolk General Hospital (Norfolk, VA) between April 1, 2009, and March 31, 2010. P...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2012.12.011
更新日期：2013-03-01 00:00:00
abstract：:The use of pacemakers and implantable cardioverter-defibrillators continues to increase for the management of cardiac dysrhythmias and, more recently, heart failure. Long-term complications associated with their use include infection, lead failure, and spurious shocks. Although the risk of infection with intracardiac ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/79.4.549
更新日期：2004-04-01 00:00:00
abstract：:A 71-year-old man had painful blue toes after an episode of protracted vomiting. Abdominal, cardiac, and transesophageal ultrasound studies were performed before angiography was considered. A large mobile mass in the proximal descending thoracic aorta, which suggested thrombus, was identified by transesophageal echoca...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)60048-2
更新日期：1993-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the outcomes of robotic mitral valve repair (MVr) by primary indication per American Heart Association guidelines for surgery: class I vs class IIa. PATIENTS AND METHODS:From January 1, 2008, through September 30, 2016, 603 patients underwent robotic MVr for severe primary mitral regurgitation. M...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2019.05.025
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:To assess whether patients with pancreatic cancer-associated pain living near a pain control center were more likely to undergo neurolytic celiac plexus block (NCPB) than those living at a distance and to determine the rationale of physicians at our institution for referring patients for NCPB. DESIGN:We retr...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/72.9.831
更新日期：1997-09-01 00:00:00
abstract：:Myocarditis, an inflammatory disease of heart muscle, is an important cause of dilated cardiomyopathy worldwide. Viral infection is also an important cause of myocarditis, and the spectrum of viruses known to cause myocarditis has changed in the past 2 decades. Several new diagnostic methods, such as cardiac magnetic ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/S0025-6196(11)60670-8
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the association between coffee consumption and mortality from all causes and from cardiovascular disease. PATIENTS AND METHODS:Data from the Aerobics Center Longitudinal Study representing 43,727 participants with 699,632 person-years of follow-up were included. Baseline data were collected by an...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2013.06.020
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVE:To assess the current spectrum of causes and clinical features associated with hypersensitivity pneumonitis (HP). PATIENTS AND METHODS:We studied consecutive patients with HP diagnosed at the Mayo Clinic in Rochester, Minn, from January 1, 1997, through December 31, 2002. Diagnostic criteria for HP included ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/82.7.812
更新日期：2007-07-01 00:00:00
abstract：:Type 2 diabetes mellitus is a heterogeneous disorder characterized by 2 pathogenic defects, impaired insulin secretion and insulin resistance. The resultant hyperglycemia causes microvascular and macrovascular complications that increase morbidity and mortality in patients with diabetes mellitus. Optimum glycemic cont...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：
更新日期：2001-06-01 00:00:00
abstract：:Endoscopic esophageal variceal sclerotherapy (EVS) is often used in the treatment of upper gastrointestinal hemorrhage due to esophageal varices. We retrospectively reviewed the Mayo Clinic experience with EVS between 1980 and 1989 to determine the incidence of thoracic manifestations and chest roentgenographic abnorm...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)62086-2
更新日期：1991-07-01 00:00:00
abstract：:The neurologist has become increasingly involved in the multidisciplinary treatment of patients with chronic noncancer pain (CNP). Chronic noncancer pain affects a diverse patient population with multiple underlying diagnoses and associated therapies. Following the model of the American Board of Anesthesiology and the...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/78.1.80
更新日期：2003-01-01 00:00:00
abstract：:The feasibility and accuracy of continuous-wave Doppler echocardiography in measuring pressure gradients across the pulmonary artery band were assessed. Simultaneous continuous-wave Doppler and catheter pressure measurements were prospectively performed in 20 patients with complex congenital heart disease and prior pu...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)65584-0
更新日期：1984-11-01 00:00:00
abstract：OBJECTIVE:To investigate the predictors of monoclonal gammopathy of undetermined significance (MGUS) by considering not only the initial features but also the pattern of evolution of the M protein during the first years after diagnosis. PATIENTS AND METHODS:This study consisted of 359 patients diagnosed as having MGUS...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/82.4.428
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVE:To compare health care usage between suicide decedents and living controls in the year before suicide in a large representative US population. PATIENTS AND METHODS:Cases (n=1221) and controls (n=3663) belonged to an integrated health care system from January 1, 2009, through December 31, 2014. Cases and cont...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2019.04.037
更新日期：2019-10-01 00:00:00
abstract：:Platelets from normal pigs and pigs with von Willebrand's disease were studied by ultrastructural and scanning electron microscopy. The majority of resting platelets were discoid or abortive-dendritic in gross morphology with an average size of 2.6 micrometer. The number of alpha-granules per platelet section was vari...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：:Neuroepidemiology has been important in providing clues about the cause and pathogenesis of multiple sclerosis. In this review, we update the incidence and prevalence rates of multiple sclerosis in Olmsted County, Minnesota, and examine the potential role of viruses, exposure to animals, toxins, trauma, and diet in th...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)61754-6
更新日期：1989-07-01 00:00:00
abstract：:People with hypertension have a high prevalence of insulin resistance and are at relatively high risk of developing type 2 diabetes mellitus. It is becoming increasingly evident that antihypertensive agents have disparate metabolic effects. For example, recent clinical trials indicate that agents that interrupt the re...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/81.6.796
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVE:To describe management of patients with permanent pacemaker (PPM)- and implantable cardioverter-defibrillator (ICD)-related endocarditis. PATIENTS AND METHODS:We retrospectively reviewed all cases of infection involving PPMs and ICDs among patients presenting to Mayo Clinic's site in Rochester, MN, between J...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/83.1.46
更新日期：2008-01-01 00:00:00
