Monoclonal gammopathy of undetermined significance: predictors of malignant transformation and recognition of an evolving type characterized by a progressive increase in M protein size.

abstract：OBJECTIVE:To evaluate the long-term prognostic effect of resting heart rate (HR) at index myocardial infarction (MI) and during the first year after MI among 1-year survivors. PATIENTS AND METHODS:The community-based cohort consisted of 1571 patients hospitalized with an incident MI from January 1, 1983, through Decem...

journal_title：Mayo Clinic proceedings

authors： Jabre P,Roger VL,Weston SA,Adnet F,Jiang R,Vivien B,Empana JP,Jouven X

更新日期：2014-12-01 00:00:00

abstract：:As alternatives to transurethral resection of the prostate for treatment of benign prostatic hyperplasia, various types of laser prostatectomy-most notably, neodymium:yttrium-aluminum-garnet (YAG) and potassium titanyl phosphate laser procedures-have proved to be associated with considerably less morbidity (for exampl...

journal_title：Mayo Clinic proceedings

authors： Kabalin JN,Gilling PJ,Fraundorfer MR

更新日期：1998-08-01 00:00:00

abstract：:We conducted a prospective, randomized trial to study the efficacy and tolerance of long-term versus short-term treatment with recombinant interferon alfa-2a in patients with chronic hepatitis B. Ten patients were randomly assigned to a 6-month interferon regimen, and 10 patients were assigned to a 3-week interferon t...

journal_title：Mayo Clinic proceedings

authors： Rakela J,Wood JR,Czaja AJ,O'Brien PC,Taswell HF,Bowyer BA,Lange SM,Anderson ML,Parent K

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and tolerability of weekly oral cyclophosphamide in combination with alternate-day prednisone (CP) as salvage therapy for patients with relapsed multiple myeloma (MM) after autologous stem cell transplantation (ASCT). PATIENTS AND METHODS:We retrospectively reviewed the medical records...

journal_title：Mayo Clinic proceedings

authors： Trieu Y,Trudel S,Pond GR,Mikhael J,Jaksic W,Reece DE,Chen CI,Stewart AK

更新日期：2005-12-01 00:00:00

abstract：:Breast cancer is the most common noncutaneous malignancy among every major ethnic group of women in the United States. Anthracyclines and taxanes are the most active and widely used chemotherapeutic agents for breast cancer, but the increased use of these agents at an early stage of disease often renders tumors resist...

journal_title：Mayo Clinic proceedings

authors： Moreno-Aspitia A,Perez EA

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To describe the two variants of Castleman's disease--the hyaline-vascular type and the plasma-cell type--and discuss the associated histologic features. DESIGN:We present a case of the hyaline-vascular type and review the literature. RESULTS:Castleman's disease was once thought to be localized and self-limi...

journal_title：Mayo Clinic proceedings

authors： Shahidi H,Myers JL,Kvale PA

更新日期：1995-10-01 00:00:00

abstract：:Staphylococcus lugdunensis, a coagulase-negative staphylococcus, is being increasingly recognized as the cause of serious infections. We report 2 cases of total knee arthroplasty infection caused by S lugdunensis. S lugdunensis frequently produces a clumping factor that can result in a positive slide (short) coagulase...

journal_title：Mayo Clinic proceedings

authors： Sampathkumar P,Osmon DR,Cockerill FR 3rd

更新日期：2000-05-01 00:00:00

abstract：:At the McGill University neuro-ophthalmology unit, 52 patients with superior oblique palsy were seen during the 2-year period October 1973 to August 1975; these included patients with congenital, traumatic, vascular, and other more rare causes of trochlear paralysis. Half of the patients with congenital palsy had dipl...

journal_title：Mayo Clinic proceedings

authors： Younge BR,Sutula F

更新日期：1977-01-01 00:00:00

abstract：:Cirrhosis and its disease-related complications are the 12th leading cause of mortality among U.S. adults and are the 5th leading cause of death for individuals aged 45 to 54 years. Hospitalization costs for disease-related complications are estimated at 18,000 dollars per episode of care, and 10% of admitted patients...

journal_title：Mayo Clinic proceedings

authors： Talwalkar JA,Kamath PS

更新日期：2005-11-01 00:00:00

abstract：:Hepatitis C virus infection is common, often silent, and almost always chronic and can lead to cirrhosis and hepatocellular cancer. Deaths related to chronic hepatitis C are expected to increase dramatically in the future. Many cases of infection are asymptomatic and are undiagnosed because of a lack of recognition by...

journal_title：Mayo Clinic proceedings

authors： Gross JB Jr

更新日期：1998-04-01 00:00:00

abstract：:Type 2 diabetes mellitus (DM) is a major cardiovascular (CV) risk factor and, as such, is considered a coronary artery disease risk equivalent. Although glycemic control is associated with decreased CV events epidemiologically, many prospective clinical trials have failed to conclusively demonstrate that aggressive gl...

journal_title：Mayo Clinic proceedings

authors： O'Keefe JH,Abuannadi M,Lavie CJ,Bell DS

更新日期：2011-02-01 00:00:00

abstract：:This discussion concerns an overview of our considerations of the adrenergic nervous system with respect to those areas of the nervous system that provide direct sensory input to the brain in control of arterial pressure; those brain centers that also participate in regulating arterial pressure; certain neurohumoral c...

journal_title：Mayo Clinic proceedings

authors： Frohlich ED

更新日期：1977-06-01 00:00:00

abstract：OBJECTIVE:To review the association of coronary artery calcification with coronary atherosclerosis and its potential clinical application as detected on electron beam computed tomography (EBCT). DESIGN:A literature review of coronary artery calcification, coronary artery disease, and EBCT is presented, and clinical ap...

journal_title：Mayo Clinic proceedings

authors： Rumberger JA,Sheedy PF 2nd,Breen JF,Fitzpatrick LA,Schwartz RS

更新日期：1996-04-01 00:00:00

abstract：:There appears to be a spectrum of psychogenic urinary retention that is seen mostly in women. The degrees of psychiatric disorder and bladder disorder do not necessarily coincide. Some patients with psychogenic retention may have one acute episode temporally related to psychologic trauma. Others may present with probl...

journal_title：Mayo Clinic proceedings

authors： Barrett DM

更新日期：1976-06-01 00:00:00

abstract：OBJECTIVE:To assess presentation, imaging, treatment, and outcome of patients with myelopathy due to a dural arteriovenous fistula (DAVF). PATIENTS AND METHODS:This retrospective review identified 94 patients with DAVF surgically treated at our institution between June 1985 and December 1999. The mean ages of the 75 m...

journal_title：Mayo Clinic proceedings

authors： Atkinson JL,Miller GM,Krauss WE,Marsh WR,Piepgras DG,Atkinson PP,Brown RD Jr,Lane JI

更新日期：2001-11-01 00:00:00

abstract：:Type I anti-neuronal nuclear autoantibodies (ANNA-I, also known as "Hu") are a distinctive serologic marker of small cell lung carcinoma (SCLC) in patients who have peripheral neuropathies or encephalomyeloradiculopathies. A tumor antigen reactive with these antibodies has been identified by other investigators by Wes...

journal_title：Mayo Clinic proceedings

authors： Kiers L,Altermatt HJ,Lennon VA

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To determine the attitudes of Olmsted County, Minnesota, adults about environmental tobacco smoke in restaurants, bars, and nightclubs. SUBJECTS AND METHODS:In this population survey,2014 adults were contacted by random digit dial methods between February 28 and May 5, 2000, and asked to participate in a tel...

journal_title：Mayo Clinic proceedings

authors： Kottke TE,Aase LA,Brandel CL,Brekke MJ,Brekke LN,DeBoer SW,Hayes SN,Hoffman RS,Menzel PA,Thomas RJ

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To provide a practical formula for fresh frozen plasma (FFP) dosing for warfarin reversal. PATIENTS AND METHODS:We reviewed data on all adult patients who received a total of 7778 units of FFP for warfarin reversal at Sentara Norfolk General Hospital (Norfolk, VA) between April 1, 2009, and March 31, 2010. P...

journal_title：Mayo Clinic proceedings

authors： Rashidi A,Tahhan HR

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To assess the results of laparoscopic splenectomy as a treatment for immune thrombocytopenic purpura (ITP). MATERIAL AND METHODS:We conducted a retrospective study of all patients who underwent laparoscopic splenectomy for ITP at our institution between August 1992 and May 1997. RESULTS:Of 27 patients who u...

journal_title：Mayo Clinic proceedings

authors： Harold KL,Schlinkert RT,Mann DK,Reeder CB,Noel P,Fitch TR,Braich TA,Camoriano JK

更新日期：1999-01-01 00:00:00

abstract：:Although measurements of trunk flexibility are an important part of a clinical examination, subjective methods are usually used to assess spinal mobility. We studied three easily performed objective techniques for determining trunk flexibility (the common "fingertip-to-floor" test, the modified Schober and Moll tests,...

journal_title：Mayo Clinic proceedings

authors： Merritt JL,McLean TJ,Erickson RP,Offord KP

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:To measure the effect of duty periods no longer than 16 hours on patient care and resident education. PATIENTS AND METHODS:As part of our Educational Innovations Project, we piloted a novel resident schedule for an inpatient service that eliminated shifts longer than 16 hours without increased staffing or de...

journal_title：Mayo Clinic proceedings

authors： McCoy CP,Halvorsen AJ,Loftus CG,McDonald FS,Oxentenko AS

更新日期：2011-03-01 00:00:00

abstract：:Aerobic exercise training has been used as part of the treatment for a variety of chronic disorders, most notably cardiovascular disease. In order to determine the feasibility and utility of regular exercise after renal transplantation, the responses of 10 patients to graded exercise testing were compared before train...

journal_title：Mayo Clinic proceedings

authors： Miller TD,Squires RW,Gau GT,Ilstrup DM,Frohnert PP,Sterioff S

更新日期：1987-09-01 00:00:00

abstract：:Transesophageal echocardiography (TEE) is used frequently in patients with cerebrovascular ischemia. On TEE, a typical appearance of a cardiac fibroelastoma is that of a pedunculated, mobile mass attached to a leaflet of a valve. Surgical excision of the lesion may lead to resolution of the symptoms and prevent furthe...

journal_title：Mayo Clinic proceedings

authors： Brown RD Jr,Khandheria BK,Edwards WD

更新日期：1995-09-01 00:00:00

abstract：:With the ever-expanding elderly population in the United States, benign prostatic hyperplasia (BPH) has become a widespread condition. Although surgical intervention (open prostatectomy and transurethral resection of the prostate) was the typical management approach for BPH in the past, other options currently include...

journal_title：Mayo Clinic proceedings

authors： Blute ML,Larson TR,Hanson KA,King BF

更新日期：1998-06-01 00:00:00

abstract：:Treatment of seniors with Parkinson disease is within the domain of primary care physicians and internists. A good working knowledge of carbidopa/levodopa principles should allow excellent care of most patients, at least during the early years of the disease. Even later, when levodopa responses become more complicated...

journal_title：Mayo Clinic proceedings

authors： Ahlskog JE

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To assess the impact of direct-to-consumer (DTC) predictive genomic risk information on perceived risk and worry in the context of routine clinical care. PATIENTS AND METHODS:Patients attending a preventive medicine clinic between June 1 and December 18, 2009, were randomly assigned to receive either genomic...

journal_title：Mayo Clinic proceedings

authors： James KM,Cowl CT,Tilburt JC,Sinicrope PS,Robinson ME,Frimannsdottir KR,Tiedje K,Koenig BA

更新日期：2011-10-01 00:00:00

abstract：:There are a number of changes underway in modern clinical bacteriology laboratories. Panel-based molecular diagnostics are now available for numerous applications, including, but not limited to, detection of bacteria and select antibacterial resistance markers in positive blood culture bottles, detection of acute gast...

journal_title：Mayo Clinic proceedings

authors： Patel R

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To assess whether patients with pancreatic cancer-associated pain living near a pain control center were more likely to undergo neurolytic celiac plexus block (NCPB) than those living at a distance and to determine the rationale of physicians at our institution for referring patients for NCPB. DESIGN:We retr...

journal_title：Mayo Clinic proceedings

authors： Brown DL,Caswell RE,Wong GY,Nauss LA,Offord KP

更新日期：1997-09-01 00:00:00

abstract：:Frequently, the presence of endocarditis is disguised. The emphasis of this description of the clinical manifestations of endocarditis is on the various modes of presentation, rather than on individual symptoms and signs. Endocarditis can manifest with cardiac, pulmonary, ophthalmic, central nervous system, renal, ort...

journal_title：Mayo Clinic proceedings

authors： Hermans PE

更新日期：1982-01-01 00:00:00

abstract：:Traditional treatments for men with localized prostate cancer have included both surgical removal and radiation therapy, with their potential adverse effects on patient quality of life. Thus, there has been increasing interest in the development of minimally invasive procedures that use various technologies to deliver...

journal_title：Mayo Clinic proceedings

authors： Gillett MD,Gettman MT,Zincke H,Blute ML

更新日期：2004-12-01 00:00:00