Abstract:
:The feasibility and accuracy of continuous-wave Doppler echocardiography in measuring pressure gradients across the pulmonary artery band were assessed. Simultaneous continuous-wave Doppler and catheter pressure measurements were prospectively performed in 20 patients with complex congenital heart disease and prior pulmonary artery banding. In two other patients, adequate Doppler signals could not be obtained. Doppler velocity was converted to pressure gradient by using the modified Bernoulli equation. Simultaneous continuous-wave Doppler spectral envelopes and catheter pressure wave forms were digitized at 10-ms intervals to obtain maximal instantaneous, mean, and peak-to-peak pressure gradients. The maximal Doppler gradient ranged from 23 to 154 mm Hg, and the simultaneous maximal catheter pressure gradient ranged from 34 to 168 mm Hg. The correlation (r) between these two measurements had a coefficient of 0.98 and a standard error of the estimate (SEE) of 7 mm Hg. The peak-to-peak systolic gradient ranged from 17 to 156 mm Hg and correlated with the maximal Doppler gradient (r = 0.95; SEE = 11 mm Hg). The mean Doppler and mean catheter pressure gradients also were correlated (r = 0.93; SEE = 9 mm Hg). As Doppler echocardiography measures instantaneous velocity and therefore instantaneous pressure gradient, the more precise correlation was between Doppler gradient and maximal instantaneous catheter gradient rather than peak-to-peak systolic gradient. Continuous-wave Doppler echocardiography is an accurate noninvasive technique for measurement of pressure gradients across pulmonary artery bands. In combination with clinical evaluation and two-dimensional echocardiography, it should substantially aid clinical decision making.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Fyfe DA,Currie PJ,Seward JB,Tajik AJ,Reeder GS,Mair DD,Hagler DJdoi
10.1016/s0025-6196(12)65584-0subject
Has Abstractpub_date
1984-11-01 00:00:00pages
744-50issue
11eissn
0025-6196issn
1942-5546pii
S0025-6196(12)65584-0journal_volume
59pub_type
杂志文章abstract::During the past decade, major advances have been made in vitamin D research that transcend the simple concept that vitamin D is Important for the prevention of rickets in children and has little physiologic relevance for adults. Inadequate vitamin D, in addition to causing rickets, prevents children from attaining the...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.4065/81.3.353
更新日期:2006-03-01 00:00:00
abstract::Rapid eye movement sleep behavior disorder (RBD) is diagnosed by a clinical history of dream enactment accompanied by polysomnographic rapid eye movement sleep atonia loss (rapid eye movement sleep without atonia). Rapid eye movement sleep behavior disorder is strongly associated with neurodegenerative disease, especi...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.mayocp.2017.09.007
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the treatment strategies for primary and secondary management of malignancy-related pericardial effusions. PATIENTS AND METHODS:Retrospective review of Mayo Clinic Rochester charts and external records of patients with pericardial effusion associated with malignant disease who required treatment ...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/75.3.248
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:To describe clinical, radiological, and histopathologic features of diffuse bronchiolar disease due to chronic occult aspiration. PATIENTS AND METHODS:We identified 4 patients encountered from July 2001 to January 2004 who had persistent respiratory symptoms and lung Infiltrates and who were eventually diagn...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/81.2.172
更新日期:2006-02-01 00:00:00
abstract::Clopidogrel bisulfate, a widely used inhibitor of platelet aggregation, is considered at least as safe as aspirin. We describe a patient who developed a systemic inflammatory response syndrome consisting of high fever, tachycardia, cellulitis-like rash, impaired liver function, and mild leukopenia after receiving clop...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/78.5.618
更新日期:2003-05-01 00:00:00
abstract::Peritoneovenous shunt for intractable ascites was complicated by disseminated intravascular coagulation, which resulted in the death of the patient. Attention is called to this potentially serious complication. The cause of disseminated intravascular coagulation occurring after peritoneovenous shunt is uncertain. Pati...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1978-08-01 00:00:00
abstract::The first generation of multicenter randomized controlled trials of coronary artery bypass surgery vs medical treatment in the 1970s found survival advantage only in patients with left main coronary artery disease or with multiple risk factors. Over time, these results have remained reproducible and biologically plaus...
journal_title:Mayo Clinic proceedings
pub_type:
doi:10.4065/77.1.72
更新日期:2002-01-01 00:00:00
abstract::Generalized convulsive status epilepticus (GCSE) is a medical emergency that may be associated with severe neuronal injury. The mortality attributable to GCSE ranges from 3 to 35%. The disorder occurs most frequently in the young and the old extremes of the population. GCSE commonly occurs in patients with no history ...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/S0025-6196(11)64844-1
更新日期:1996-08-01 00:00:00
abstract::Scleromyxedema is a disorder characterized by a typical rash due to the accumulation of mucin in the dermis. It is always associated with a monoclonal protein in the serum and can have a wide variety of systemic manifestations. We describe a 40-year-old woman who had scleromyxedema associated with a monoclonal G lambd...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/74.5.481
更新日期:1999-05-01 00:00:00
abstract::Dual-chamber pacing improved hemodynamics acutely in a subset of patients with left ventricular (LV) dysfunction but conveyed no long-term symptomatic benefit in most. More recently, LV pacing and biventricular (multisite) pacing have been used to improve systolic contractility by altering the electrical and mechanica...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/S0025-6196(11)63225-4
更新日期:2001-08-01 00:00:00
abstract::Because fasting nerve myo-inositol (myo-Ins) is not decreased in patients with diabetes treated conventionally, in whom neuropathy may develop or may have already developed, it seems unlikely that myo-Ins is the metabolic abnormality that initiates diabetic neuropathy, if nerve myo-Ins is not spuriously high during fa...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)61217-8
更新日期:1989-08-01 00:00:00
abstract:OBJECTIVE:To assess whether caffeine intake is associated with all-cause and cause-specific mortality. PATIENTS AND METHODS:We conducted a prospective cohort study using data from the National Health and Nutrition Examination Survey 1999-2010. Cox proportional hazards models were used to compare the multivariate-adjus...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/j.mayocp.2017.03.010
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To determine relationships among pregnancy (during and postpartum), acute pancreatitis, and gallstones. PATIENTS AND METHODS:In this retrospective population-based case-control study, we identified all 12- to 50-year-old Rochester, Minn, females diagnosed between 1976 and 1991 as having acute pancreatitis (c...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/75.4.361
更新日期:2000-04-01 00:00:00
abstract::We describe a patient who had severe myalgias, bronchial asthma, pulmonary infiltrates, and eosinophilia. The findings on physical examination and the erythrocyte sedimentation rate were normal; there was no elevation of the serum creatine kinase. Muscle biopsy demonstrated an inflammatory exudate that contained eosin...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)62663-9
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To assess presentation, imaging, treatment, and outcome of patients with myelopathy due to a dural arteriovenous fistula (DAVF). PATIENTS AND METHODS:This retrospective review identified 94 patients with DAVF surgically treated at our institution between June 1985 and December 1999. The mean ages of the 75 m...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/76.11.1120
更新日期:2001-11-01 00:00:00
abstract::Many types of psychotherapeutic drugs (especially antidepressants) directly and indirectly interact with neurotransmitter receptors, the recognition sites for the chemical messengers released by neurons. These interactions can result in increased or decreased sensitivity of certain receptors. Hypotheses exist to expla...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract:OBJECTIVE:To record long-term follow-up data on patients with chronic idiopathic meningitis. DESIGN:We retrospectively reviewed the outcome of 49 patients who were examined at the Mayo Clinic between 1978 and 1990. MATERIAL AND METHODS:For all patients, symptoms, signs, laboratory values, results of imaging studies, ...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)62246-0
更新日期:1994-06-01 00:00:00
abstract::Evidence that host immunologic function may influence the behavior of lung cancer is accumulating. Non-small-cell lung cancers are heavily infiltrated by host lymphocytes. The fact that monoclonal antibodies have been developed against lung cancer cells implies that such cells express surface antigens and are therefor...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/s0025-6196(12)60137-2
更新日期:1993-04-01 00:00:00
abstract::Pergolide is a potent dopamine agonist and is known to have anti-Parkinson properties. We administered pergolide to patients with suboptimal control of Parkinson's disease who had a short-duration response to carbidopa-levodopa in a 6-month, double-blind study. Pergolide added to the carbidopa-levodopa regimen resulte...
journal_title:Mayo Clinic proceedings
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0025-6196(12)64911-8
更新日期:1988-10-01 00:00:00
abstract::A calcium-binding IgG K monoclonal protein in a patient with multiple myeloma and asymptomatic hypercalcemia was recognized, isolated, and characterized. In addition to binding by the whole IgG molecules, calcium was bound by purified Fab fragments and recombined heavy and light chains. In a competitive binding study,...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract::We reviewed the results of preoperative screening laboratory tests in asymptomatic healthy patients who underwent elective surgical procedures at our institution in 1988. Substantially abnormal results were found in 160 of 3,782 patients. All such abnormalities involved five tests: aspartate aminotransferase, glucose,...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)60487-x
更新日期:1991-02-01 00:00:00
abstract:OBJECTIVE:To examine the association of medical knowledge acquisition with attendance at specific conference types during internal medicine residency. PARTICIPANTS AND METHODS:Attendance at residency core curriculum, morbidity and mortality, and medical grand rounds conferences was tracked for 195 residents who took t...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/83.4.449
更新日期:2008-04-01 00:00:00
abstract::Given the burden of cardiovascular disease (CVD), increasing the prevalence of healthy lifestyle choices is a global imperative. Currently, cardiac rehabilitation programs are a primary way that modifiable risk factors are addressed in the secondary prevention setting after a cardiovascular (CV) event/diagnosis. Even ...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.mayocp.2013.03.002
更新日期:2013-06-01 00:00:00
abstract::We conducted a prospective, randomized trial to study the efficacy and tolerance of long-term versus short-term treatment with recombinant interferon alfa-2a in patients with chronic hepatitis B. Ten patients were randomly assigned to a 6-month interferon regimen, and 10 patients were assigned to a 3-week interferon t...
journal_title:Mayo Clinic proceedings
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0025-6196(12)62144-2
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVE:To determine the risk of hospitalization and death in relation to preexisting depression and anxiety among patients with cardiovascular disease (CVD). PATIENTS AND METHODS:The cohort consisted of 799 Olmsted County, MN, residents diagnosed with CVD (myocardial infarction or heart failure) from January 1, 197...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/mcp.2011.0148
更新日期:2011-11-01 00:00:00
abstract::B-cell chronic lymphocytic leukemia (B-CLL) is a relatively indolent hematologic malignant disease that, despite a good response to nonaggressive orally administered chemotherapy, currently remains incurable. The overall median duration of survival is more than 5 years, and the presence of anemia or thrombocytopenia a...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/s0025-6196(12)61551-1
更新日期:1992-04-01 00:00:00
abstract::After the completion of the Human Genome Project, there has been an acceleration in methodologies on sequencing nucleic acids (DNA and RNA) at a high precision and with ever-decreasing turnaround time and cost. Collectively, these approaches are termed next-generation sequencing and are already affecting the transform...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.mayocp.2017.03.002
更新日期:2017-05-01 00:00:00
abstract::Data from animal experiments and human studies implicate added sugars (eg, sucrose and high-fructose corn syrup) in the development of diabetes mellitus and related metabolic derangements that raise cardiovascular (CV) risk. Added fructose in particular (eg, as a constituent of added sucrose or as the main component o...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.mayocp.2014.12.019
更新日期:2015-03-01 00:00:00
abstract::To assess the nature and prognosis of severe chronic active hepatitis of unknown cause, we compared 26 patients who had been fully screened for etiologic factors with 112 patients who had autoimmune chronic active hepatitis after similar durations of corticosteroid therapy (17(+)/- 2 versus 23 (+)/- 2 months), and fol...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)62106-5
更新日期:1990-01-01 00:00:00
abstract::Eighty-two consecutive orthopedic patients were assessed nutritionally at the time of hospital admission and then at 10-day intervals until hospital dismissal. Forty-eight percent of the patients had one or more abnormal findings suggestive of protein-calorie malnutrition. In spite of this prevalence of abnormal findi...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00