Clinician's guide to hepatitis C.

Abstract:

:Hepatitis C virus infection is common, often silent, and almost always chronic and can lead to cirrhosis and hepatocellular cancer. Deaths related to chronic hepatitis C are expected to increase dramatically in the future. Many cases of infection are asymptomatic and are undiagnosed because of a lack of recognition by patients and physicians. All patients currently or previously at risk of infection should undergo screening, including those who received blood transfusions before 1992. Interferon is the only effective therapy, but disappearance of virus is sustained in only 10 to 15% of patients. The combination of interferon and oral ribavirin therapy may increase the sustained response rate to about 40%. New agents such as hepatitis C virus-specific protease inhibitors may be available in the next 5 to 10 years, and treatment is evolving toward multiple-drug regimens analogous to those used for human immunodeficiency virus (HIV) infection. In contrast to public funding for drug development in HIV, such funding for hepatitis C has been limited.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Gross JB Jr

doi

10.1016/S0025-6196(11)63702-6

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

355-60; quiz 361

issue

4

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)63702-6

journal_volume

73

pub_type

杂志文章,评审
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    authors: Schomberg PJ,Evans RG,Banks PM,White WL,O'Connell MJ,Earle JD

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  • Breast cancer in DES-exposed mothers: absence of association.

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    authors: Brian DD,Tilley BC,Labarthe DR,O'Fallon WM,Noller KL,Kurland LT

    更新日期:1980-02-01 00:00:00

  • Transesophageal atrial pacing in the Wolff-Parkinson-White syndrome.

    abstract::In a patient with Wolff-Parkinson-White syndrome, protracted, disabling tachycardia occurred because of low left lateral accessory pathway refractoriness and rapid retrograde conduction, most likely by a septal pathway. Conventional medications, including intravenously administered lidocaine and procainamide, were ine...

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    authors: Hartzler GO,Maoloney JD

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    authors: Hossein-nezhad A,Holick MF

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    doi:10.1016/s0025-6196(12)64916-7

    authors: de Groen PC

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    pub_type: 杂志文章

    doi:

    authors: Carpenter HA,Lancaster JR,Lee RA

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  • A computerized simulator for critical-care training: new technology for medical education.

    abstract::A patient simulator has been developed for training, certification, modeling, and demonstrating problems in the management of critical-care patients. The Critical Care & Hemodynamic Monitoring Training System consists of a personal computer, software, and a replica of a human torso designed to enable students to pract...

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    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)65158-1

    authors: Saliterman SS

    更新日期:1990-07-01 00:00:00

  • Percutaneous transcatheter embolization of coronary arteriovenous fistulas.

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    doi:10.4065/71.1.37

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  • Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers.

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    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.mayocp.2012.10.021

    authors: Liu R,Li L,Yang M,Boden G,Yang G

    更新日期:2013-02-01 00:00:00

  • Botulinum Toxin in Parkinson Disease Tremor: A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach.

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    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.mayocp.2017.06.010

    authors: Mittal SO,Machado D,Richardson D,Dubey D,Jabbari B

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    pub_type: 杂志文章

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  • Thymic hyperplasia presenting as anterior mediastinal mass in 2 patients with Graves disease.

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    pub_type: 杂志文章

    doi:10.4065/77.5.495

    authors: Budavari AI,Whitaker MD,Helmers RA

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  • Lichen Planopilaris in Women: A Retrospective Review of 232 Women Seen at Mayo Clinic From 1992 to 2016.

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    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2020.02.028

    authors: Larkin SC,Cantwell HM,Imhof RL,Torgerson RR,Tolkachjov SN

    更新日期:2020-08-01 00:00:00

  • Leuconostoc bacteremia in an infant with short-gut syndrome: case report and literature review.

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    doi:10.4065/71.12.1171

    authors: Dhodapkar KM,Henry NK

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    abstract::Increased intracranial pressure can result in irreversible injury to the central nervous system. Among the many functions of the cerebrospinal fluid, it provides protection against acute changes in venous and arterial blood pressure or impact pressure. Nevertheless, trauma, tumors, infections, neurosurgical procedures...

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    pub_type: 杂志文章,评审

    doi:10.1016/s0025-6196(12)65131-3

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    更新日期:1990-05-01 00:00:00

  • Minimally invasive radical prostatectomy.

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    journal_title:Mayo Clinic proceedings

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    doi:10.4065/79.9.1169

    authors: Humphreys MR,Gettman MT,Chow GK,Zincke H,Blute ML

    更新日期:2004-09-01 00:00:00

  • Management and extended outcome of patients with synchronous bilateral solid renal neoplasms in the absence of von Hippel-Lindau disease.

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    doi:10.4065/75.10.1020

    authors: Blute ML,Amling CL,Bryant SC,Zincke H

    更新日期:2000-10-01 00:00:00

  • Risk of breast cancer and breast cancer characteristics in women treated with supradiaphragmatic radiation for Hodgkin lymphoma: Mayo Clinic experience.

    abstract:OBJECTIVE:To evaluate the overall risk of breast cancer and breast cancer characteristics in women given supradiaphragmatic radiation therapy for Hodgkin lymphoma. PATIENTS AND METHODS:Medical records of 653 female patients who received supradiaphragmatic radiation therapy for Hodgkin lymphoma at the Mayo Clinic in Ro...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/78.6.708

    authors: Wahner-Roedler DL,Nelson DF,Croghan IT,Achenbach SJ,Crowson CS,Hartmann LC,O'Fallon WM

    更新日期:2003-06-01 00:00:00

  • Therapeutic Effects and Mechanisms of Action of Rifaximin in Gastrointestinal Diseases.

    abstract::Emerging preclinical and clinic evidence described herein suggests that the mechanism of action of rifaximin is not restricted to direct antibacterial effects within the gastrointestinal tract. Data from this study were derived from general and clinical trial-specific PubMed searches of English-language articles on ri...

    journal_title:Mayo Clinic proceedings

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    doi:10.1016/j.mayocp.2015.04.016

    authors: DuPont HL

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  • Effect of glutathione infusion on leg arterial circulation, cutaneous microcirculation, and pain-free walking distance in patients with peripheral obstructive arterial disease: a randomized, double-blind, placebo-controlled trial.

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    pub_type: 临床试验,杂志文章,随机对照试验

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    abstract:OBJECTIVE:To determine whether sirolimus therapy is associated with neurologic complications, including stroke, among heart transplant recipients. PATIENTS AND METHODS:We retrospectively studied patients who underwent heart transplant at Mayo Clinic's site in Rochester, MN, from January 1, 1988, through June 30, 2006....

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    pub_type: 杂志文章

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  • Effect of Preprocedural Thrombocytopenia on Prognosis After Percutaneous Coronary Intervention.

    abstract:OBJECTIVE:To assess early and late outcomes, including bleeding, in patients with thrombocytopenia undergoing percutaneous coronary intervention (PCI). PATIENTS AND METHODS:We performed a retrospective single-center study of patients with preprocedural thrombocytopenia (platelet count ≤100,000/μL; n=204) undergoing PC...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2016.05.008

    authors: Raphael CE,Spoon DB,Bell MR,Psaltis PJ,Kidd S,Loh SX,Lennon RJ,Singh M,Rihal C,Gulati R

    更新日期:2016-08-01 00:00:00

  • Wegener's granulomatosis associated with vasculitis of the temporal artery: report of five cases.

    abstract::Between January 1973 and October 1991 at the Mayo Clinic, 5 of 345 patients with Wegener's granulomatosis initially had features suggestive of giant cell arteritis and subsequently were found to have biopsy-proven vasculitis of the temporal artery. All five patients were older than 60 years of age and had jaw claudica...

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    doi:10.1016/s0025-6196(12)60157-8

    authors: Nishino H,DeRemee RA,Rubino FA,Parisi JE

    更新日期:1993-02-01 00:00:00

  • Evaluating the patient with diarrhea: a case-based approach.

    abstract::The evaluation of the patient with diarrhea can be complex and the treatment challenging. In this article, the definition of diarrhea and the pathophysiologic mechanisms that lead to diarrhea are reviewed. A simplified 5-step approach to the patient with diarrhea is provided and applied in a case-oriented manner appli...

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    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2012.02.015

    authors: Sweetser S

    更新日期:2012-06-01 00:00:00

  • Q fever: epidemiology, diagnosis, and treatment.

    abstract::Q fever, a zoonosis caused by Coxiella burnetii, is seen throughout the world. Recent reports suggest that its incidence in the United States is increasing, with more than 30 cases reported in the US military. The disease has many acute and chronic manifestations. Endocarditis is the most common form of chronic diseas...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/83.5.574

    authors: Hartzell JD,Wood-Morris RN,Martinez LJ,Trotta RF

    更新日期:2008-05-01 00:00:00

  • Increased cancer risks in myotonic dystrophy.

    abstract:OBJECTIVE:To estimate cancer risks for patients with myotonic dystrophy, given that increased risks for neoplasms in association with myotonic dystrophy type 1 and type 2 have been suggested in several studies but the risks of cancers have not been quantified. PATIENTS AND METHODS:A cohort of 307 patients with myotoni...

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    pub_type: 杂志文章

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    authors: Win AK,Perattur PG,Pulido JS,Pulido CM,Lindor NM

    更新日期:2012-02-01 00:00:00

  • Recalcitrant pyoderma gangrenosum treated with thalidomide.

    abstract::Pyoderma gangrenosum is a painful, noninfectious, ulcerating skin disorder often associated with systemic disease. Thalidomide has been used to treat many inflammatory dermatologic conditions and has been reintroduced in the United States to treat immune-modulated diseases such as pyoderma gangrenosum. The patient des...

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    journal_title:Mayo Clinic proceedings

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    doi:10.4065/81.10.1345

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  • Bronchoscopic phototherapy with hematoporphyrin derivative for treatment of localized bronchogenic carcinoma: a 5-year experience.

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