Cerebrospinal fluid physiology and the management of increased intracranial pressure.

Abstract:

:Increased intracranial pressure can result in irreversible injury to the central nervous system. Among the many functions of the cerebrospinal fluid, it provides protection against acute changes in venous and arterial blood pressure or impact pressure. Nevertheless, trauma, tumors, infections, neurosurgical procedures, and other factors can cause increased intracranial pressure. Both surgical and nonsurgical therapeutic modalities can be used in the management of increased intracranial pressure attributable to traumatic and nontraumatic causes. In patients with cerebral injury and increased intracranial pressure, monitoring of the intracranial pressure can provide an objective measure of the response to therapy and the pressure dynamics. Intraventricular, intraparenchymal, subarachnoid, and epidural sites can be used for monitoring, and the advantages and disadvantages of the various devices available are discussed. With the proper understanding of the physiologic features of the cerebrospinal fluid, the physician can apply the management principles reviewed herein to minimize damage from intracranial hypertension.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Lyons MK,Meyer FB

doi

10.1016/s0025-6196(12)65131-3

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

684-707

issue

5

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(12)65131-3

journal_volume

65

pub_type

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