Increased left atrial volume index: potent biomarker for first-ever ischemic stroke.

Abstract:

OBJECTIVE:To establish the incidence and correlation of increased left atrial volume index (LAVI) in patients with first-ever ischemic stroke. PARTICIPANTS AND METHODS:Using our institution's epidemiological database, we defined a cohort of 432 patients (cases) who underwent transthoracic echocardiography within 60 days of first ischemic stroke between January 1, 1985, and December 31, 1994. Left atrial volume was measured with the biplane area-length method, indexed to body surface area (LAVI, expressed as mL/m(2)). The control group consisted of 416 community residents who underwent transthoracic echocardiography as participants in a stroke risk factor study. Increased LAVI was defined as 28 mL/m(2) or higher. Survival in patients was compared with expected survival among white Minnesotans and was further modeled as a function of age, sex, LAVI, and clinical risk factors. RESULTS:Among the included 306 patients, 230 (75%) had increased LAVI (mean+/-SD, 49+/-21 mL/m(2)). Patients with increased LAVI were older than those with normal LAVI (mean+/-SD age, 76+/-11 vs 71+/-13 years; P=.003) and had more cardiovascular risk factors (mean+/-SD number, 1.8+/-0.07 vs 1.3+/-0.89; P<.001). Mean LAVI was higher in cases than in age- and sex-matched controls (P<.001). At 5-year follow-up, cases showed excess mortality compared with age-matched controls (P=.001). After variables were adjusted for age, sex, and clinical risk factors, LAVI was independently associated with mortality. CONCLUSION:A useful index for prediction of adverse cardiovascular events, LAVI might also predict first ischemic stroke and subsequent mortality.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Fatema K,Bailey KR,Petty GW,Meissner I,Osranek M,Alsaileek AA,Khandheria BK,Tsang TS,Seward JB

doi

10.4065/83.10.1107

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

1107-15

issue

10

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)60616-2

journal_volume

83

pub_type

杂志文章
  • Ideal cardiovascular health and mortality: Aerobics Center Longitudinal Study.

    abstract:OBJECTIVE:To analyze the relationship of ideal cardiovascular health to disease-specific death. PATIENTS AND METHODS:We used data from the Aerobics Center Longitudinal Study from October 9, 1987, to March 3, 1999, to estimate the prevalence of ideal cardiovascular health in 11,993 individuals (24.3% women) and to exam...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2012.07.015

    authors: Artero EG,España-Romero V,Lee DC,Sui X,Church TS,Lavie CJ,Blair SN

    更新日期:2012-10-01 00:00:00

  • Antiproliferative effect of the somatostatin analogue octreotide on growth hormone-producing pituitary tumors: results of a multicenter randomized trial.

    abstract:OBJECTIVE:To determine and quantify the in vivo effects of octreotide on the cell cycle kinetics of growth hormone-producing pituitary adenomas. DESIGN:A multicenter randomized trial had been conducted to assess the clinical efficacy of octreotide, and we studied tissue specimens from pituitary macroadenomas in 32 pat...

    journal_title:Mayo Clinic proceedings

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/S0025-6196(11)63358-2

    authors: Thapar K,Kovacs KT,Stefaneanu L,Scheithauer BW,Horvath E,Lloyd RV,Li J,Laws ER Jr

    更新日期:1997-10-01 00:00:00

  • Prognostic value of cardiac troponin T after myocardial infarction: a contemporary community experience.

    abstract:OBJECTIVE:To evaluate the role of cardiac troponin T (cTnT) in predicting death, recurrent ischemic events, and heart failure among community-dwelling persons with first myocardial infarction (MI). PATIENTS AND METHODS:Consecutive Olmsted County, Minnesota, residents with an incident MI between November 6, 2002, and D...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2011.11.013

    authors: Gerber Y,Jaffe AS,Weston SA,Jiang R,Roger VL

    更新日期:2012-03-01 00:00:00

  • Evolving role of the neurologist in the diagnosis and treatment of chronic noncancer pain.

    abstract::The neurologist has become increasingly involved in the multidisciplinary treatment of patients with chronic noncancer pain (CNP). Chronic noncancer pain affects a diverse patient population with multiple underlying diagnoses and associated therapies. Following the model of the American Board of Anesthesiology and the...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/78.1.80

    authors: Jacobson PL,Mann JD

    更新日期:2003-01-01 00:00:00

  • Patterns of multiple myeloma during the past 5 decades: stable incidence rates for all age groups in the population but rapidly changing age distribution in the clinic.

    abstract:OBJECTIVE:To define age-adjusted incidence trends in multiple myeloma (MM) in a well-characterized population during a long period, given that some, but not all, studies have reported increasing MM incidence over time and that clinical experience from some centers suggests an increased incidence mainly in younger age g...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/mcp.2009.0426

    authors: Turesson I,Velez R,Kristinsson SY,Landgren O

    更新日期:2010-03-01 00:00:00

  • Periprocedural anticoagulation management of patients with nonvalvular atrial fibrillation.

    abstract:OBJECTIVE:To estimate the 3-month cumulative incidence of thromboembolism (TE), bleeding, and death among consecutive patients with nonvalvular atrial fibrillation (AF) who were receiving long-term anticoagulation therapy and were referred to the Thrombophilia Center at Mayo Clinic for periprocedural anticoagulation ma...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/83.6.639

    authors: Wysokinski WE,McBane RD,Daniels PR,Litin SC,Hodge DO,Dowling NF,Heit JA

    更新日期:2008-06-01 00:00:00

  • Neurologic recovery following prolonged out-of-hospital cardiac arrest with resuscitation guided by continuous capnography.

    abstract::A 54-year-old man with no known cardiac disease collapsed outdoors in a small rural community. The cardiac arrest was witnessed, and immediate cardiopulmonary resuscitation was begun by a bystander and a trained first responder who was nearby. The patient was moved into a building across the street for continued resus...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/mcp.2011.0229

    authors: White RD,Goodman BW,Svoboda MA

    更新日期:2011-06-01 00:00:00

  • Temporal Trends in Resource Use, Cost, and Outcomes of Transcatheter Aortic Valve Replacement in the United States.

    abstract:OBJECTIVE:To evaluate the contemporary trends in outcomes and resource use associated with transcatheter aortic valve replacement (TAVR) in the United States. METHODS:We identified patients who underwent TAVR between January 1, 2012, and December 31, 2017, in the National Readmission Database. We assessed temporal tre...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2020.05.043

    authors: Kawsara A,Sulaiman S,Linderbaum J,Coffey SR,Alqahtani F,Nkomo VT,Crestanello JA,Alkhouli M

    更新日期:2020-12-01 00:00:00

  • Scleromyxedema: a complete response to prednisone.

    abstract::Scleromyxedema is a disorder characterized by a typical rash due to the accumulation of mucin in the dermis. It is always associated with a monoclonal protein in the serum and can have a wide variety of systemic manifestations. We describe a 40-year-old woman who had scleromyxedema associated with a monoclonal G lambd...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/74.5.481

    authors: Rayson D,Lust JA,Duncan A,Su WP

    更新日期:1999-05-01 00:00:00

  • Providing Appropriate End-of-Life Care to Religious and Ethnic Minorities.

    abstract::There is overwhelming evidence that racial and ethnic minorities face multiple health care disparities. Recognizing and addressing cultural and religious/spiritual (RS) values is a critical aspect of providing goal-concordant care for patients facing a serious illness, especially at the end of life. Failure to address...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.mayocp.2016.08.024

    authors: Partain DK,Ingram C,Strand JJ

    更新日期:2017-01-01 00:00:00

  • Neurovascular microsurgery: a model for laboratory investigation and the development of technical skills.

    abstract::An inexpensive and reproducible model to help in developing the technical skills for, and to investigate experimentally, a microvascular anastomosis resembling the superficial temporal-middle cerebral artery bypass is described. The model is used to illustrate the important principles of microvascular surgery. Using a...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Rosenbaum TJ,Sundt TM Jr

    更新日期:1976-05-01 00:00:00

  • Generalized convulsive status epilepticus.

    abstract::Generalized convulsive status epilepticus (GCSE) is a medical emergency that may be associated with severe neuronal injury. The mortality attributable to GCSE ranges from 3 to 35%. The disorder occurs most frequently in the young and the old extremes of the population. GCSE commonly occurs in patients with no history ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/S0025-6196(11)64844-1

    authors: Cascino GD

    更新日期:1996-08-01 00:00:00

  • Allergen immunotherapy.

    abstract::Allergen immunotherapy involves exposing a patient to a gradually escalating dose of a specific allergen with the intention of decreasing allergic and inflammatory responses, ultimately leading to a sustained decrease in allergic symptoms. A build-up phase (once weekly injections) is followed by a maintenance phase (o...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/82.9.1119

    authors: Rank MA,Li JT

    更新日期:2007-09-01 00:00:00

  • Use of the Coronary Artery Calcium Score in Discussion of Initiation of Statin Therapy in Primary Prevention.

    abstract::Clinical guidelines for instituting pharmacotherapy for the primary prevention of atherosclerotic cardiovascular disease (ASCVD), specifically lipid management and aspirin, have long been based on absolute risk. However, lipid management in the current era remains challenging to both patients and clinicians in the set...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2017.10.001

    authors: Michos ED,Blaha MJ,Blumenthal RS

    更新日期:2017-12-01 00:00:00

  • Matched comparison of radical nephrectomy vs nephron-sparing surgery in patients with unilateral renal cell carcinoma and a normal contralateral kidney.

    abstract:OBJECTIVE:To report the long-term follow-up of a matched comparison of radical nephrectomy (RN) and nephron-sparing surgery (NSS) in patients with single unilateral renal cell carcinoma (RCC) and a normal contralateral kidney. PATIENTS AND METHODS:Between August 1966 and March 1999, 1492 and 189 patients with unilater...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/75.12.1236

    authors: Lau WK,Blute ML,Weaver AL,Torres VE,Zincke H

    更新日期:2000-12-01 00:00:00

  • Coryneform bacterial endocarditis: difficulties in diagnosis and treatment, presentation of three cases, and review of literature.

    abstract::Three patients who had coryneform bacterial endocarditis affecting a prosthetic valve are presented and 64 case reports are reviewed. Diagnostic difficulties occur because coryneform bacteria often are fastidiuos, with long incubation periods, and often contaminate blood cultures. Although some coryneform bacteria are...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Van Scoy RE,Cohen SN,Geraci JE,Washington JA 2nd

    更新日期:1977-04-01 00:00:00

  • Congenital heart disease associated with selective serotonin reuptake inhibitor use during pregnancy.

    abstract:OBJECTIVE:To determine the risk of congenital cardiac abnormalities associated with use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy. PATIENTS AND METHODS:We conducted a retrospective review of the medical records of all pregnant women presenting at Mayo Clinic's site in Rochester, MN, from Janu...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/84.1.23

    authors: Wichman CL,Moore KM,Lang TR,St Sauver JL,Heise RH Jr,Watson WJ

    更新日期:2009-01-01 00:00:00

  • Dehydroepiandrosterone replacement therapy in hypoadrenal women: protein anabolism and skeletal muscle function.

    abstract:OBJECTIVE:To determine whether dehydroepiandrosterone (DHEA) replacement therapy in hypoadrenal women improves performance, muscle protein accretion, and mitochondrial functions. PARTICIPANTS AND METHODS:Thirty-three hypoadrenal women were enrolled in the study from May 1, 2002, through May 31, 2003. Twenty-eight comp...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,随机对照试验

    doi:10.4065/83.11.1218

    authors: Dhatariya KK,Greenlund LJ,Bigelow ML,Thapa P,Oberg AL,Ford GC,Schimke JM,Nair KS

    更新日期:2008-11-01 00:00:00

  • Autogenic biofeedback treatment for migraine.

    abstract::Autogenic biofeedback training appears to be a promising technique for the treatment of migraine headaches, as reflected in the literature reviewed herein and in the data from 21 patients who were followed up for an average of 10 months. Autogenic biogeedback training exemplifies an important trend in psychosomatic me...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:

    authors: Fahrion SL

    更新日期:1977-12-01 00:00:00

  • Sustained-release niacin for prevention of migraine headache.

    abstract::Considerable advances in the diagnosis and treatment of migraine headache have occurred during the past decade, but treatment options for acute migraine attacks have expanded at a faster rate than those for prophylaxis. We describe a patient whose migraine headaches responded dramatically to sustained-release niacin a...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/78.6.770

    authors: Velling DA,Dodick DW,Muir JJ

    更新日期:2003-06-01 00:00:00

  • Brain metastatic lesions.

    abstract:OBJECTIVE:To describe current concepts in the diagnosis and treatment of brain metastases. RESULTS:More than 25% of all autopsy-proven brain metastases have a pulmonary source. Most brain metastases manifest with a combination of focal and generalized symptoms and signs. Typically, patients have subacute, progressive ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/s0025-6196(12)61374-3

    authors: O'Neill BP,Buckner JC,Coffey RJ,Dinapoli RP,Shaw EG

    更新日期:1994-11-01 00:00:00

  • Diagnosis of obesity by primary care physicians and impact on obesity management.

    abstract:OBJECTIVE:To evaluate whether primary care physicians document obesity as a diagnosis and formulate a management plan. PATIENTS AND METHODS:The Mayo Clinic primary care database was used to identify general medical examinations performed from November 1, 2004, to October 31, 2005, in a primary care clinic for obese pa...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/82.8.927

    authors: Bardia A,Holtan SG,Slezak JM,Thompson WG

    更新日期:2007-08-01 00:00:00

  • Omega-3 fatty acids for cardioprotection.

    abstract::The most compelling evidence for the cardiovascular benefit provided by omega-3 fatty acids comes from 3 large controlled trials of 32,000 participants randomized to receive omega-3 fatty acid supplements containing docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) or to act as controls. These trials showed r...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/83.3.324

    authors: Lee JH,O'Keefe JH,Lavie CJ,Marchioli R,Harris WS

    更新日期:2008-03-01 00:00:00

  • Survey of physician leadership and management education.

    abstract::Health-care organizations have recognized the need to prepare physicians for various leadership and management positions within their own institutions. In the past, those who desired further education had to search beyond the boundaries of their practice to fulfill this need. The demands of a dynamic and changing heal...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/S0025-6196(11)63574-X

    authors: Scott HM,Tangalos EG,Blomberg RA,Bender CE

    更新日期:1997-07-01 00:00:00

  • Discriminate value of esophageal symptoms: a study of the initial clinical findings in 499 patients with dysphagia of various causes.

    abstract::The aim of this study was to determine whether the characteristics of esophageal symptoms may be of diagnostic utility in distinguishing dysphagia of various causes. Included in the study were a total of 499 patients with three types of dysphagia: 234 with dysphagia related to an obstructive lesion in the esophagus, 1...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)62266-6

    authors: Kim CH,Weaver AL,Hsu JJ,Rainwater L,Zinsmeister AR

    更新日期:1993-10-01 00:00:00

  • The Impact of a 20-Minute Animal-Assisted Activity Session on the Physiological and Emotional States in Patients With Fibromyalgia.

    abstract:OBJECTIVE:To study the direct physiological and emotional impact of an animal-assisted activity (AAA) session (a form of complementary and integrative medicine) in patients with fibromyalgia (FM). PATIENTS AND METHODS:The study population consisted of 221 participants with FM who were attending Mayo Clinic's Fibromyal...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.mayocp.2020.04.037

    authors: Clark S,Martin F,McGowan RTS,Smidt J,Anderson R,Wang L,Turpin T,Langenfeld-McCoy N,Bauer B,Mohabbat AB

    更新日期:2020-11-01 00:00:00

  • Gestational diabetes mellitus: now is the time for detection and treatment.

    abstract::The extent of universal screening for gestational diabetes and the incidence of gestational diabetes mellitus (GDM) by diagnosis were analyzed in four primary-care sites. The medical records of 798 women were reviewed to identify the presence of historical risk factors, familial determinants, and biophysical attribute...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)60932-x

    authors: Mazze RS,Krogh CL

    更新日期:1992-10-01 00:00:00

  • Symptomatic hyperthyroidism in a patient taking the dietary supplement tiratricol.

    abstract::An 87-year-old woman was referred for evaluation of nervousness, tremor, insomnia, and fatigue of 2 months' duration. Initial laboratory evaluation revealed a suppressed thyrotropin level and an elevated triiodothyronine level. A review of her medications revealed that she had started taking several dietary supplement...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/77.6.587

    authors: Bauer BA,Elkin PL,Erickson D,Klee GG,Brennan MD

    更新日期:2002-06-01 00:00:00

  • Making the Case to Study the Volume-Outcome Relationship in Hematologic Cancers.

    abstract::The positive relationship between the volume of health services (hospital and physician) and health-related outcomes is established in the complex surgical treatment of cancers and certain nononcologic medical conditions. However, this topic has not been systematically explored in the medical management of cancers. We...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.mayocp.2015.07.003

    authors: Go RS,Bottner WA,Gertz MA

    更新日期:2015-10-01 00:00:00

  • Clinical features and prognostic implications of severe corticosteroid-treated cryptogenic chronic active hepatitis.

    abstract::To assess the nature and prognosis of severe chronic active hepatitis of unknown cause, we compared 26 patients who had been fully screened for etiologic factors with 112 patients who had autoimmune chronic active hepatitis after similar durations of corticosteroid therapy (17(+)/- 2 versus 23 (+)/- 2 months), and fol...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)62106-5

    authors: Czaja AJ,Hay JE,Rakela J

    更新日期:1990-01-01 00:00:00