Thymic hyperplasia presenting as anterior mediastinal mass in 2 patients with Graves disease.


:Graves disease is an autoimmune thyroid condition characterized by the production of autoantibodies against the thyrotropin receptor. The autoantibodies mimic the effect of the hormone on thyroid cells, which stimulates autonomous production of thyroxine and triiodothyronine. It has been hypothesized that cross-reactivity of autoantibodies may result in Graves ophthalmopathy and dermopathy. A seldom-recognized feature of Graves disease is thymic hyperplasia. We report 2 patients with Graves disease and incidentally discovered anterior mediastinal masses presumed to be thymic hyperplasia. In both cases, these masses regressed spontaneously after treatment of hyperthyroidism.


Mayo Clin Proc


Mayo Clinic proceedings


Budavari AI,Whitaker MD,Helmers RA





Has Abstract


2002-05-01 00:00:00














  • Neurovascular microsurgery: a model for laboratory investigation and the development of technical skills.

    abstract::An inexpensive and reproducible model to help in developing the technical skills for, and to investigate experimentally, a microvascular anastomosis resembling the superficial temporal-middle cerebral artery bypass is described. The model is used to illustrate the important principles of microvascular surgery. Using a...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Rosenbaum TJ,Sundt TM Jr

    更新日期:1976-05-01 00:00:00

  • Laparoscopy for the definitive diagnosis of intra-abdominal lymphoma.

    abstract:OBJECTIVE:To assess the efficacy of laparoscopy in the diagnosis of intra-abdominal lymphoma. PATIENTS AND METHODS:The medical records of patients with suspected primary or recurrent lymphoma who underwent laparoscopy between March 1991 and March 2003 were reviewed. Demographic, clinical, operative, and pathologic dat...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Asoglu O,Porter L,Donohue JH,Cha SS

    更新日期:2005-05-01 00:00:00

  • Horseshoe kidney associated with surgery of the abdominal aorta.

    abstract::Of 53 patients with horseshoe kidney (9 in the present series), 45 underwent operation for an abdominal aortic aneurysm: 40 electively and 5 on an emergency basis. The remaining eight patients underwent revascularization for arteriosclerosis obliterans. Of the 53 patients, 35 (66%) had renal artery anomalies. The anom...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Sidell PM,Pairolero PC,Payne WS,Bernatz PE,Spittel JA Jr

    更新日期:1979-02-01 00:00:00

  • Digital embolization from plaque-related thrombus in the thoracic aorta: identification with transesophageal echocardiography and resolution with warfarin therapy.

    abstract::A 71-year-old man had painful blue toes after an episode of protracted vomiting. Abdominal, cardiac, and transesophageal ultrasound studies were performed before angiography was considered. A large mobile mass in the proximal descending thoracic aorta, which suggested thrombus, was identified by transesophageal echoca...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Blackshear JL,Jahangir A,Oldenburg WA,Safford RE

    更新日期:1993-03-01 00:00:00

  • Age-Related 2-Year Mortality After Transcatheter Aortic Valve Replacement: the YOUNG TAVR Registry.

    abstract:OBJECTIVE:To comparatively assess the natural history of patients of different ages undergoing transcatheter aortic valve replacement (TAVR). PATIENTS AND METHODS:For this study, we used the YOUNG TAVR, an international, multicenter registry investigating mortality trends up to 2 years in patients with aortic valve st...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,多中心研究


    authors: Navarese EP,Andreotti F,Kołodziejczak M,Wanha W,Lauten A,Veulemans V,Frediani L,Kubica J,de Cillis E,Wojakowski W,Ochala A,Zeus T,Bortone A,Buffon A,Jung C,Pestrichella V,Gurbel PA

    更新日期:2019-08-01 00:00:00

  • Management of Advanced Penile Cancer.

    abstract::Penile squamous cell carcinoma (PSCC) is a rare cancer, with approximately 2000 new cases in the United States and 35,000 globally every year. Multiple risk factors are involved in PSCC, but most importantly, the high-risk human papillomavirus infection is thought to be present in approximately 50% of cases. Penile sq...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Chahoud J,Kohli M,Spiess PE

    更新日期:2020-12-08 00:00:00

  • Intraoperative echocardiography in valvular heart disease: an evidence-based appraisal.

    abstract::Intraoperative (IO) transesophageal echocardiography (TEE) is widely used for assessing the results of valvular heart disease (VHD) surgery. Epiaortic ultrasonography (EAU) has been recommended for prevention of perioperative strokes. To what extent does high-quality evidence justify the widespread use of these imagin...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,meta分析,评审


    authors: Michelena HI,Abel MD,Suri RM,Freeman WK,Click RL,Sundt TM,Schaff HV,Enriquez-Sarano M

    更新日期:2010-07-01 00:00:00

  • Management and extended outcome of patients with synchronous bilateral solid renal neoplasms in the absence of von Hippel-Lindau disease.

    abstract:OBJECTIVE:To gain information regarding long-term follow-up in patients with synchronous bilateral solid renal neoplasms in whom renal-preserving surgery is imperative. PATIENTS AND METHODS:We examined our surgical experience and the survival outcome, as evaluated by Kaplan-Meier and log-rank analysis, of 94 patients ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Blute ML,Amling CL,Bryant SC,Zincke H

    更新日期:2000-10-01 00:00:00

  • Wegener's granulomatosis associated with vasculitis of the temporal artery: report of five cases.

    abstract::Between January 1973 and October 1991 at the Mayo Clinic, 5 of 345 patients with Wegener's granulomatosis initially had features suggestive of giant cell arteritis and subsequently were found to have biopsy-proven vasculitis of the temporal artery. All five patients were older than 60 years of age and had jaw claudica...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Nishino H,DeRemee RA,Rubino FA,Parisi JE

    更新日期:1993-02-01 00:00:00

  • Intensive-care unit experience in the Mayo liver transplantation program: the first 100 cases.

    abstract::The first 100 liver transplantations at the Mayo Clinic were performed in 83 patients, who required a total of 917 patient days in the intensive-care unit (ICU). The mean duration of stay in the ICU was 5.91 days after liver transplantation and 6.15 days for patients who subsequently required readmission to the ICU. D...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Plevak DJ,Southorn PA,Narr BJ,Peters SG

    更新日期:1989-04-01 00:00:00

  • An overview of the diagnosis and pharmacologic treatment of migraine.

    abstract::Migraine, an episodic headache disorder, is one of the most common complaints encountered by primary-care physicians and neurologists. Nevertheless, it remains underdiagnosed and undertreated. Rational migraine treatment necessitates an accurate diagnosis, identification and removal of potential triggering factors, an...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Capobianco DJ,Cheshire WP,Campbell JK

    更新日期:1996-11-01 00:00:00

  • Cutaneous malignant melanoma.

    abstract::Skin cancer has become the most common neoplasm in the United States. With early diagnosis and appropriate management, most skin cancers have an overall 5-year survival rate of 95%. Cutaneous malignant melanoma (CMM), however, has a significantly higher morbidity and mortality, resulting in 65% of all skin cancer deat...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Cummins DL,Cummins JM,Pantle H,Silverman MA,Leonard AL,Chanmugam A

    更新日期:2006-04-01 00:00:00

  • Radical Prostatectomy Trends in the United States: 1998 to 2011.

    abstract:OBJECTIVE:To determine the incidence and distribution of radical prostatectomy (RP) in the United States over time. PATIENTS AND METHODS:We conducted a serial cross-sectional analysis of time trends using the Nationwide Inpatient Sample of adult men older than 45 years who underwent RP between January 1, 1998, and Dec...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Tyson MD 2nd,Andrews PE,Ferrigni RF,Humphreys MR,Parker AS,Castle EP

    更新日期:2016-01-01 00:00:00

  • Flu myths: dispelling the myths associated with live attenuated influenza vaccine.

    abstract::Live attenuated influenza vaccine (LAIV), commercially available since 2003, has not gained widespread acceptance among prescribers. This underuse can be traced to several misperceptions and fears regarding LAIV. This review examines both the facts (safety, immunogenicity, and effectiveness) and the most pervasive myt...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Tosh PK,Boyce TG,Poland GA

    更新日期:2008-01-01 00:00:00

  • Treating tobacco dependence in light of the 2008 US Department of Health and Human Services clinical practice guideline.

    abstract::Cigarette smoking is the most important preventable cause of morbidity, mortality, and excess health care costs in the United States. From 2000 through 2004, cigarette smoking caused an estimated annual average of 443,595 deaths and cost $193 billion per year in smoking-attributable productivity losses and smoking-rel...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Hays JT,Ebbert JO,Sood A

    更新日期:2009-08-01 00:00:00

  • Effect of glutathione infusion on leg arterial circulation, cutaneous microcirculation, and pain-free walking distance in patients with peripheral obstructive arterial disease: a randomized, double-blind, placebo-controlled trial.

    abstract:OBJECTIVE:To assess the effects of glutathione on pain-free walking distance (PFWD) and hemodynamic parameters in patients with peripheral artery disease. PATIENTS AND METHODS:Forty patients with Fontaine stage II peripheral artery disease who were seen between September 2000 and March 2001 at the vascular laboratory ...

    journal_title:Mayo Clinic proceedings

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Arosio E,De Marchi S,Zannoni M,Prior M,Lechi A

    更新日期:2002-08-01 00:00:00

  • Importance of Rapid Eye Movement Sleep Behavior Disorder to the Primary Care Physician.

    abstract::Sleep disorders and neurodegenerative diseases are commonly encountered in primary care. A common, but underdiagnosed sleep disorder, rapid eye movement sleep behavior disorder (RBD), is highly associated with Parkinson disease and related disorders. Rapid eye movement sleep behavior disorder is common. It is estimate...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: McCarter SJ,Howell MJ

    更新日期:2016-10-01 00:00:00

  • Maintaining quality of life at the end of life.

    abstract::Despite the successful growth of the hospice movement during the past 30 years in the United States, almost 85% of Americans continue to die in hospitals or nursing homes. While the benefits of palliative care principles are well established, palliative care interventions remain underused in clinical practice in the s...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Rummans TA,Bostwick JM,Clark MM,Mayo Clinic Cancer Center Quality of Life Working Group.

    更新日期:2000-12-01 00:00:00

  • Attitudes of Olmsted County, Minnesota, residents about tobacco smoke in restaurants and bars.

    abstract:OBJECTIVE:To determine the attitudes of Olmsted County, Minnesota, adults about environmental tobacco smoke in restaurants, bars, and nightclubs. SUBJECTS AND METHODS:In this population survey,2014 adults were contacted by random digit dial methods between February 28 and May 5, 2000, and asked to participate in a tel...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Kottke TE,Aase LA,Brandel CL,Brekke MJ,Brekke LN,DeBoer SW,Hayes SN,Hoffman RS,Menzel PA,Thomas RJ

    更新日期:2001-02-01 00:00:00

  • Early experience with a universal (DDD) pacing device.

    abstract::To assess the advantages and complications of a new universal (DDD) pacemaker, we studied retrospectively the initial 38 patients who received such a pacing device. This group consisted of 27 men and 11 women whose ages ranged from 23 to 89 years. The pacemaker was the initial one for 32 patients and was the replaceme...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Hayes DL,Holmes DR Jr,Vlietstra RE

    更新日期:1983-05-01 00:00:00

  • Olmesartan, other antihypertensives, and chronic diarrhea among patients undergoing endoscopic procedures: a case-control study.

    abstract:OBJECTIVE:To investigate a recent association between the use of the angiotensin receptor-blocker (ARB) olmesartan and a severe enteropathy resembling celiac disease. PATIENTS AND METHODS:We searched our endoscopy database for all outpatient esophagogastroduodenoscopy (EGD) or colonoscopy examinations in patients aged...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Greywoode R,Braunstein ED,Arguelles-Grande C,Green PH,Lebwohl B

    更新日期:2014-09-01 00:00:00

  • Cardiovascular responses to immersion in a hot tub in comparison with exercise in male subjects with coronary artery disease.

    abstract::In order to test the safety of hot tub use for persons with heart disease, 15 men with clinically stable coronary artery disease underwent 15 minutes of immersion in a hot tube at 40 degrees C. On another day, they exercised on a cycle ergometer for 15 minutes; target heart rate was determined by standard methods. Tym...

    journal_title:Mayo Clinic proceedings

    pub_type: 临床试验,杂志文章


    authors: Allison TG,Miller TD,Squires RW,Gau GT

    更新日期:1993-01-01 00:00:00

  • Immune thrombocytopenias: tests for platelet antibodies.

    abstract::In a study of 49 consecutive patients for whom a test for platelet antibodies had been ordered, tests were performed for both cell-bound and serum platelet antibodies. In cases of autoimmune thrombocytopenia (ITP), the test result for cell-bound antibody was more likely to be positive than was the test result for seru...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Moore SB,Wick MR,Richardson LM

    更新日期:1984-12-01 00:00:00

  • Update on Treatment of Clostridioides difficile Infection.

    abstract::Clostridioides difficile infection (CDI) is the leading cause of health care-associated infections in the United States. The increasing incidence and recurrence rates of CDI together with its associated morbidity and mortality are great concerns. Newer treatment methods, such as narrow-spectrum antibiotics, monoclonal...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Cho JM,Pardi DS,Khanna S

    更新日期:2020-04-01 00:00:00

  • Urinary incontinence in the elderly population.

    abstract:OBJECTIVE:To describe the causes, evaluation, and management of urinary incontinence in the elderly population. DESIGN:We reviewed pertinent articles in the medical literature and summarized the types of incontinence and contributing factors. RESULTS:Urinary incontinence is common in elderly patients and often has a ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Chutka DS,Fleming KC,Evans MP,Evans JM,Andrews KL

    更新日期:1996-01-01 00:00:00

  • Diffuse bronchiolar disease due to chronic occult aspiration.

    abstract:OBJECTIVE:To describe clinical, radiological, and histopathologic features of diffuse bronchiolar disease due to chronic occult aspiration. PATIENTS AND METHODS:We identified 4 patients encountered from July 2001 to January 2004 who had persistent respiratory symptoms and lung Infiltrates and who were eventually diagn...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Barnes TW,Vassallo R,Tazelaar HD,Hartman TE,Ryu JH

    更新日期:2006-02-01 00:00:00

  • High prevalence of vitamin D inadequacy and implications for health.

    abstract::During the past decade, major advances have been made in vitamin D research that transcend the simple concept that vitamin D is Important for the prevention of rickets in children and has little physiologic relevance for adults. Inadequate vitamin D, in addition to causing rickets, prevents children from attaining the...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Holick MF

    更新日期:2006-03-01 00:00:00

  • An obligation for primary care physicians to prescribe physical activity to sedentary patients to reduce the risk of chronic health conditions.

    abstract::Physical inactivity increases the risk of many chronic disorders. Numerous studies have convincingly demonstrated that undertaking and maintaining moderate levels of physical activity (eg, brisk walking 3 hours a week) greatly reduces the incidence of developing many chronic health conditions, most notably type 2 diab...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Chakravarthy MV,Joyner MJ,Booth FW

    更新日期:2002-02-01 00:00:00

  • Temporal Trends in Resource Use, Cost, and Outcomes of Transcatheter Aortic Valve Replacement in the United States.

    abstract:OBJECTIVE:To evaluate the contemporary trends in outcomes and resource use associated with transcatheter aortic valve replacement (TAVR) in the United States. METHODS:We identified patients who underwent TAVR between January 1, 2012, and December 31, 2017, in the National Readmission Database. We assessed temporal tre...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Kawsara A,Sulaiman S,Linderbaum J,Coffey SR,Alqahtani F,Nkomo VT,Crestanello JA,Alkhouli M

    更新日期:2020-12-01 00:00:00

  • Carcinoid tumor of the thymus: a clinicopathologic report of seven cases with a review of the literature.

    abstract::Carcinoid tumor of the thymus is a rare neoplasm. Formerly confused with thymoma, a tumor of thymic epithelial cells, carcinoid tumor of the thymus has recently been shown to arise from cells of neuroendocrine origin that are normally present in the thymus. About half of the tumors are either functionally active (usua...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Wick MR,Scott RE,Li CY,Carney JA

    更新日期:1980-04-01 00:00:00