Thymic hyperplasia presenting as anterior mediastinal mass in 2 patients with Graves disease.

Abstract:

:Graves disease is an autoimmune thyroid condition characterized by the production of autoantibodies against the thyrotropin receptor. The autoantibodies mimic the effect of the hormone on thyroid cells, which stimulates autonomous production of thyroxine and triiodothyronine. It has been hypothesized that cross-reactivity of autoantibodies may result in Graves ophthalmopathy and dermopathy. A seldom-recognized feature of Graves disease is thymic hyperplasia. We report 2 patients with Graves disease and incidentally discovered anterior mediastinal masses presumed to be thymic hyperplasia. In both cases, these masses regressed spontaneously after treatment of hyperthyroidism.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Budavari AI,Whitaker MD,Helmers RA

doi

10.4065/77.5.495

keywords:

subject

Has Abstract

pub_date

2002-05-01 00:00:00

pages

495-9

issue

5

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)62220-9

journal_volume

77

pub_type

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