The applicability of the dependence syndrome to amphetamine.

Abstract:

:While current psychiatric taxonomies recognise a classification of amphetamine dependence, derived from the notion of an alcohol dependence syndrome, little research has validated that such a condition exists for this drug. Current amphetamine users (N = 331), were interviewed using the World Health Organization operationalisation of DSM-III-R substance dependence criteria, and a measure of the psychological components of dependence. Structural analyses indicated that a unidimensional dependence syndrome as assessed by DSM-III-R and DSM-IV criteria exists for amphetamine, and that physiological, psychological and behavioural indicators were all important in accounting for the variance in responses. It was demonstrated that the concept of a dependence syndrome is applicable to amphetamine, and that the inclusion of the amphetamine dependence syndrome in DSM-III-R and DSM-IV is valid.

journal_name

Drug Alcohol Depend

authors

Topp L,Darke S

doi

10.1016/s0376-8716(97)00111-7

subject

Has Abstract

pub_date

1997-11-25 00:00:00

pages

113-8

issue

2

eissn

0376-8716

issn

1879-0046

pii

S0376-8716(97)00111-7

journal_volume

48

pub_type

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