Epidemiological survey of the use and abuse of agonist-antagonist analgesics in the Western Pacific region.

abstract：BACKGROUND:The burden of cannabis and other illicit drug use among youth represent a serious public health problem. The aim of the present study is to explore factors associated with cannabis and other illicit drug use among Nigerian secondary school adolescents of the six geopolitical zones of the country. METHODS:A ...

journal_title：Drug and alcohol dependence

authors： Mehanović E,Virk HK,Akanidomo I,Pwajok J,Prichard G,van der Kreeft P,Vigna-Taglianti F,Unplugged Nigeria Coordination Group.

更新日期：2020-01-01 00:00:00

abstract：:To explore the mechanisms mediating the effects of acute morphine on the immune system, effects of ganglionic blockade with chlorisondamine on acute high dose morphine-induced alterations in blood lymphocyte proliferation, white blood cell counts, spleen lymphocyte proliferation and splenic natural killer (NK) cell cy...

journal_title：Drug and alcohol dependence

authors： Mellon RD,Bayer BM

更新日期：2001-04-01 00:00:00

abstract：:The information on drinking habits contained in medical records with that obtained through the CAGE alcoholism screening test was compared for 124 inpatients of a teaching general hospital. This survey was followed by testing the possibility of introducing the CAGE test into the routine clinical interview. A second an...

journal_title：Drug and alcohol dependence

authors： Jorge MR,Masur J

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Technology-based applications represent a promising method for providing efficacious, widely available interventions to substance abuse treatment patients. However, limited access to communication technology (i.e., mobile phones, computers, internet, and e-mail) could significantly impact the feasibility of ...

journal_title：Drug and alcohol dependence

authors： McClure EA,Acquavita SP,Harding E,Stitzer ML

更新日期：2013-04-01 00:00:00

abstract：:This study compared urinary 5-hydroxytryptophol (5HTOL) with breath-ethanol testing as objective ways to disclose recent drinking by outpatients attending a methadone maintenance treatment clinic. Information about quantity and frequency of alcohol use was obtained by confidential self-reports. Random screening was pe...

journal_title：Drug and alcohol dependence

authors： Helander A,von Wachenfeldt J,Hiltunen A,Beck O,Liljeberg P,Borg S

更新日期：1999-08-02 00:00:00

abstract：BACKGROUND:The present study examined (1) the association between changes in perceived parental control and support from age 13 to 15 and early onset of cannabis use (before age 16), and (2) whether personality modifies the association between a decline in perceived parental control and support and early onset of canna...

journal_title：Drug and alcohol dependence

authors： Creemers HE,Buil JM,van Lier PA,Keijsers L,Meeus W,Koot HM,Huizink AC

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:It is particularly important to survey substance use trends in populations most impacted by the consequences of substance use. Men who have sex with men (MSM) exhibit rates of methamphetamine and other substance use that exceeds those observed among other populations in the United States. Such substance use ...

journal_title：Drug and alcohol dependence

authors： Reback CJ,Fletcher JB,Shoptaw S,Grella CE

更新日期：2013-11-01 00:00:00

abstract：:Although opioid withdrawal ratings are frequently used as primary outcomes for therapeutic trials, there has been limited empirical examination of opioid withdrawal symptom onset or etiology as an outcome, and also little examination of differences in outcomes between patient-reported and observer-ratings of withdrawa...

journal_title：Drug and alcohol dependence

authors： Dunn K,Bergeria C,Huhn AS,Strain EC

更新日期：2020-10-01 00:00:00

abstract：:Cannabis sativa (marijuana plant) contains myriad cannabinoid compounds; yet, investigative attention has focused almost exclusively on Delta(9)-tetrahydrocannabinol (THC), its primary psychoactive substituent. Interest in modulation of THC's effects by these other cannabinoids (e.g., cannabidiol (CBD)) has been stimu...

journal_title：Drug and alcohol dependence

authors： Vann RE,Gamage TF,Warner JA,Marshall EM,Taylor NL,Martin BR,Wiley JL

更新日期：2008-04-01 00:00:00

abstract：:CD4(+) T lymphocytes are the primary cell target for human immunodeficiency virus-1 (HIV-1), and these cells are known to express opioid receptors. Due to the need for new treatment approaches to HIV-1 infection, we sought to determine whether the non-selective opioid receptor antagonist naltrexone would affect HIV-1 ...

journal_title：Drug and alcohol dependence

authors： Gekker G,Lokensgard JR,Peterson PK

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Herpes simplex virus type 2 (HSV-2) affects HIV acquisition, transmission, and disease progression. Effective medications for genital herpes and for HIV/AIDS exist. Parenteral transmission of HIV among persons who inject drugs is decreasing. Reducing sexual transmission of HIV and HSV-2 among persons who use...

journal_title：Drug and alcohol dependence

authors： Semaan S,Leinhos M,Neumann MS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The objective of this study was to examine depressive symptoms overtime and quantify the variance in symptoms attributable to substance use among a cohort of HIV-positive and HIV-negative men. METHODS:Participants were enrolled in an NIH/NIDA funded cohort, with 534 men resulting in 1,888 visits between Aug...

journal_title：Drug and alcohol dependence

authors： Javanbakht M,Shoptaw S,Ragsdale A,Brookmeyer R,Bolan R,Gorbach PM

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Drug checking technologies (DCTs) have been implemented as a response to the ongoing opioid overdose epidemic. We examined the level of trust people who use drugs (PWUD) have in their drug dealers as well as their perspectives on the potential for drug dealers to use DCTs to provide knowledge of drug content...

journal_title：Drug and alcohol dependence

authors： Bardwell G,Boyd J,Arredondo J,McNeil R,Kerr T

更新日期：2019-05-01 00:00:00

abstract：:Few studies have examined long-term effects of chronic cocaine use on physical health in the general population. The current study assesses the effects of chronic cocaine use by the late twenties on physical health by the mid thirties in a longitudinal cohort from the general population. Measures of physical health in...

journal_title：Drug and alcohol dependence

authors： Chen K,Scheier LM,Kandel DB

更新日期：1996-12-02 00:00:00

abstract：BACKGROUND:Despite the relatively high prevalence of marijuana use among college students, little information exists regarding health outcomes associated with different use patterns or trajectories. METHODS:Seven annual personal interviews (years 1-7) were administered to 1253 individuals, beginning in their first yea...

journal_title：Drug and alcohol dependence

authors： Caldeira KM,O'Grady KE,Vincent KB,Arria AM

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Cocaine-related deaths are continuously rising and its overdose is often associated with lethal cardiotoxic effects. METHODS AND RESULTS:Our approach, employing isothermal titration calorimetry (ITC) and light scattering in parallel, has confirmed the significant affinity of human cardiac calsequestrin (CAS...

journal_title：Drug and alcohol dependence

authors： Sanchez EJ,Hayes RP,Barr JT,Lewis KM,Webb BN,Subramanian AK,Nissen MS,Jones JP,Shelden EA,Sorg BA,Fill M,Schenk JO,Kang C

更新日期：2013-12-01 00:00:00

abstract：:Sixty-nine (9.2%) of 750 consecutive persons entering a chemical-dependence treatment hospital had urinary evidence of benzodiazepines, a somewhat higher proportion than in the general adult American population. The 54 subjects in whose urine benzodiazepines, but not the other commonly abused psychoactive drugs, were ...

journal_title：Drug and alcohol dependence

authors： Cushman P,Benzer D

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:There are limited data about the extent of DSM-5 substance use disorders (SUDs) among primary care patients. METHODS:This study analyzed data from a multisite validation study of a substance use screening instrument conducted in a diverse sample of 2000 adults aged ≥18 years recruited from five primary care...

journal_title：Drug and alcohol dependence

authors： Wu LT,McNeely J,Subramaniam GA,Brady KT,Sharma G,VanVeldhuisen P,Zhu H,Schwartz RP

更新日期：2017-10-01 00:00:00

abstract：:Pelchat and Danowski [Physiol. Behav. 1992;51:1261-1266] reported an association between the ability to taste 6-n-propylthiouracil (PROP) and a parental history of alcoholism. Kranzler et al. [Alcohol Clin. Exp. Res. 1996a;20:1496-1500] previously failed to replicate these findings in a sample of subjects with only a ...

journal_title：Drug and alcohol dependence

authors： Kranzler HR,Skipsey K,Modesto-Lowe V

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Although prenatal cocaine exposure (PCE) has been linked with greater externalizing behavior, no studies have investigated heterogeneity of developmental trajectories in children with PCE to date. The present study aimed to: (1) identify developmental trajectories of externalizing problems in childhood by us...

journal_title：Drug and alcohol dependence

authors： Min MO,Minnes S,Park H,Ridenour T,Kim JY,Yoon M,Singer LT

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:This article reports on the first web-based implementation of an opioid-overdose prevention, recognition and response training for professional first responders. The training was disseminated nationally over one listserv in November 2014. The same year, following Act 139, which mandated the provision of an o...

journal_title：Drug and alcohol dependence

authors： Simmons J,Rajan S,Goldsamt L,Elliott L

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:This study examined whether young adult marijuana use increases risk of subsequent large cigar (LC) and little cigar/cigarillo (LCC) use among naïve users. METHODS:Data were from 8 waves of the Truth Initiative Young Adult Cohort, a national sample of US young adults aged 18-34 assessed every 6 months. Disc...

journal_title：Drug and alcohol dependence

authors： Cohn AM,Johnson AL,Fryer CS,Villanti AC

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Drug-impaired driving has received increased attention resulting from development of rapid drug-screening procedures used by police and state laws establishing per se limits for drug levels in drivers. Venues that host electronic music dance events (EMDEs) provide a unique opportunity to assess drug-impaired...

journal_title：Drug and alcohol dependence

authors： Furr-Holden D,Voas RB,Kelley-Baker T,Miller B

更新日期：2006-10-15 00:00:00

abstract：:Evidence has shown that frequency and quantity of drug usage are reduced after treatment but the effect of opioid addiction treatment on alcohol consumption remains unclear. As part of the national Research Outcome Study in Ireland Evaluating drug treatment effectiveness (ROSIE, see www.nuim.ie/rosie) comprehensive dr...

journal_title：Drug and alcohol dependence

authors： Stapleton RD,Comiskey CM

更新日期：2010-02-01 00:00:00

abstract：:The cycle of tobacco dependence typically begins with the initiation of tobacco use during adolescence. Many teenagers try to quit smoking, fail and subsequently desire treatment for their tobacco dependence. Adolescents do not currently benefit from the same level of societal support for quit attempts as adults, and ...

journal_title：Drug and alcohol dependence

authors： Moolchan ET,Aung AT,Henningfield JE

更新日期：2003-06-05 00:00:00

abstract：BACKGROUND:and Aims Injecting illicit drugs in public settings has been linked to a higher risk of a range of drug-related harms, including overdose and HIV infection. However, the factors associated with public injecting among HIV-positive individuals have not been previously explored. We investigated the links betwee...

journal_title：Drug and alcohol dependence

authors： Ickowicz S,Wood E,Dong H,Nguyen P,Small W,Kerr T,Montaner JSG,Milloy MJ

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Previous studies have found individuals with family histories of alcohol use disorders are more impulsive on some but not all laboratory behavioral measures, suggesting deficits on specific forms of impulse control. However, drawing conclusions is tenuous because these different measures have not been admini...

journal_title：Drug and alcohol dependence

authors： Acheson A,Richard DM,Mathias CW,Dougherty DM

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Buprenorphine/naloxone (BUP/NX), an effective treatment for opioid dependence, has been implicated in hepatic toxicity. However, as persons taking BUP/NX have multiple hepatic risk factors, comparative data are needed to quantify the risk of hepatoxicity with BUP/NX. METHODS:We compared rates of alanine ami...

journal_title：Drug and alcohol dependence

authors： Lucas GM,Young A,Donnell D,Richardson P,Aramrattana A,Shao Y,Ruan Y,Liu W,Fu L,Ma J,Celentano DD,Metzger D,Jackson JB,Burns D,HPTN 058 study group.

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Homelessness and substance use often coexist, resulting in high morbidity. Emergency department (ED) patients have disproportionate rates of both homelessness and substance use, yet little research has examined the overlap of these issues in the ED setting. We aimed to characterize alcohol and drug use in a ...

journal_title：Drug and alcohol dependence

authors： Doran KM,Rahai N,McCormack RP,Milian J,Shelley D,Rotrosen J,Gelberg L

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:Drug dealing among drug users has been associated with elevated risk-taking and negative health outcomes. However, little is known about the cessation of drug dealing among this population. METHODS:We assessed time to cessation of drug dealing using Cox regression. We also used generalized estimating equa...

journal_title：Drug and alcohol dependence

authors： Werb D,Bouchard M,Kerr T,Shoveller J,Qi J,Montaner J,Wood E

更新日期：2011-11-01 00:00:00