Unilateral fetal mesencephalic grafts in intact rats reduce amphetamine-induced dopamine release in both striata. An in vivo voltammetric study.

abstract：:We tested a hypothesis that the classical relation between movement time and index of difficulty (ID) in quick pointing action (Fitts' Law) reflects processes at the level of motor planning. Healthy subjects stood on a force platform and performed quick and accurate hand movements into targets of different size locate...

journal_title：Neuroscience

authors： Bertucco M,Cesari P,Latash ML

更新日期：2013-02-12 00:00:00

abstract：:Here we investigated effects of intramuscular (i.m.) heating-needle stimulation on persistent muscle nociception evoked by i.m. injection of different doses (50-200 µl) of complete Freund's adjuvant (CFA) in rats. Paw withdrawal reflexes evoked by noxious mechanical and heat stimulation as well as hind limb swelling w...

journal_title：Neuroscience

authors： Lei J,Ye G,Pertovaara A,You HJ

更新日期：2020-05-01 00:00:00

abstract：:We have observed that in rat caudate-putamen nuclei, neurons immunolabeled for choline acetyltransferase were sometimes in direct apposition to unlabeled perikarya and dendrites [Pickel V. M. and Chan J. (1990) J. Neurosci. Res. 25, 263-280]. Similar juxtapositions between plasmalemmas of nerve cells each receiving in...

journal_title：Neuroscience

authors： Pickel VM,Chan J

更新日期：1991-01-01 00:00:00

abstract：:Lack of dystrophin in mdx mice leads to muscle fibre degeneration followed by the formation of new myofibres. This degeneration-regeneration event occurs in clusters. It is accompanied by inflammation and remodelling of the intramuscular terminal nerve fibres. Since the growth-associated protein B-50/GAP-43 has been s...

journal_title：Neuroscience

authors： Verzè L,Buffo A,Rossi F,Oestreicher AB,Gispen WH,Strata P

更新日期：1996-02-01 00:00:00

abstract：:The hypothesis that attention deficits induced by the hypofunction of N-methyl d-aspartate (NMDA) receptors in the prefrontal cortex (PFC) might be associated with increased glutamate release and changes in the phosphorylation of the cyclic adenosine monophosphate response element-binding protein on serine 133 (p-S(13...

journal_title：Neuroscience

authors： Pozzi L,Baviera M,Sacchetti G,Calcagno E,Balducci C,Invernizzi RW,Carli M

更新日期：2011-03-10 00:00:00

abstract：:The fenestrated microvasculature of the area postrema shows a less restrictive blood-brain barrier than is found in other areas of the CNS. We have studied the expression and relationship of vascular endothelial tight junctional proteins, astrocytes, macrophages, and the extracellular matrix with the extravasation of ...

journal_title：Neuroscience

authors： Willis CL,Garwood CJ,Ray DE

更新日期：2007-12-05 00:00:00

abstract：:Levels of the pro-inflammatory cytokine interleukin-1beta are known to be elevated in patients with chronic disorders such as Alzheimer's disease. We have investigated the effects of interleukin-1beta on long-term potentiation and N-methyl-D-aspartate receptor-mediated field potentials in the rat dentate gyrus in vitr...

journal_title：Neuroscience

authors： Coogan AN,O'Neill LA,O'Connor JJ

更新日期：1999-01-01 00:00:00

abstract：:Nogo-A interaction with its different receptors (Nogo receptor 1 (NgR1), S1P receptor 2 (S1PR2), paired immunoglobulin-like receptor B (PirB)) restricts plasticity and growth-dependent processes leading, via the activation of different signaling pathway to the stabilization of the neuronal networks (either development...

journal_title：Neuroscience

authors： Zagrebelsky M,Korte M

更新日期：2014-12-26 00:00:00

abstract：:We have reported that hypoxia affects the hypothalamic-pituitary-adrenal (HPA) axis and behavior by driving the expression of central corticotropin-releasing hormone (CRH) and its receptors in adult mammals, and this effect is modulated by other factors. Here, we address whether or not intermittent hypoxia (IH) or res...

journal_title：Neuroscience

authors： Fan JM,Chen XQ,Jin H,Du JZ

更新日期：2009-04-10 00:00:00

abstract：:The incidence of anxiety, mood, substance abuse disorders and schizophrenia increases during adolescence. Epidemiological evidence confirms that exposure to stress during sensitive periods of development can create vulnerabilities that put genetically predisposed individuals at increased risk for psychiatric disorders...

journal_title：Neuroscience

authors： Taylor SB,Taylor AR,Koenig JI

更新日期：2013-09-26 00:00:00

abstract：:In the nervous system, the aminoacylhistidine dipeptide carnosine (beta-alanyl-L-histidine) has been shown to be expressed in the olfactory receptor neurons and in brain astrocytes. Using immunocytochemical techniques, we report here a dense carnosine-like immunoreactivity in the subependymal layer of the rodent foreb...

journal_title：Neuroscience

authors： Peretto P,Bonfanti L,Merighi A,Fasolo A

更新日期：1998-07-01 00:00:00

abstract：:Mutations in γ-aminobutyric acid A receptor (GABAA) subunits and sodium channel genes, especially GABRG2 and SCN1A, have been reported to be associated with febrile seizures (FS) and genetic epilepsy with febrile seizures plus (GEFS+). GEFS+ is a well-known family of epileptic syndrome with autosomal dominant inherita...

journal_title：Neuroscience

authors： Li X,Guo S,Liu K,Zhang C,Chang H,Yang W,Rong S,Hu Q,Cui J,Wang F,Sun T

更新日期：2020-07-01 00:00:00

abstract：:Estrogens influence neuronal activity and are important for normal brain functions. Effects of estrogens on seizures are contradictory. It is commonly accepted that estrogens may increase neuronal excitability and thus mediate proconvulsant effects. However, clinical and animal data show that estrogen may also have no...

journal_title：Neuroscience

authors： Velísková J

更新日期：2006-01-01 00:00:00

abstract：:We have developed a stroke model involving middle cerebral artery occlusion in the rat which elicits changes in cardiac and autonomic variables that are similar to those observed clinically. It is likely that these neurogenic autonomic responses are mediated by changes in neurotransmitter systems subsequent to the str...

journal_title：Neuroscience

authors： Allen GV,Cheung RT,Cechetto DF

更新日期：1995-10-01 00:00:00

abstract：:Sleep is strongly implicated in learning, especially in the reprocessing of recently acquired memory. Children with intellectual disability (ID) tend to have sleep-wake disturbances, which may contribute to the pathophysiology of the disease. Given that sleep is partly controlled by the circadian clock, we decided to ...

journal_title：Neuroscience

authors： Renaud J,Dumont F,Khelfaoui M,Foisset SR,Letourneur F,Bienvenu T,Khwaja O,Dorseuil O,Billuart P

更新日期：2015-11-12 00:00:00

abstract：:Field recordings of responses to activation of corticostriatal afferents were made in coronally sectioned rat brain slices. Each recording site was categorized according to its medial to lateral and rostral to caudal position to investigate anatomical differences in synaptic plasticity. Individual responses were highl...

journal_title：Neuroscience

authors： Smith R,Musleh W,Akopian G,Buckwalter G,Walsh JP

更新日期：2001-01-01 00:00:00

abstract：:Children exposed to extreme early-life neglect such as in institutional rearing are at heightened risk for developing depression and anxiety disorders, and internalizing problems more broadly. These outcomes are believed to be due to alterations in the development of neural circuitry that supports emotion regulation. ...

journal_title：Neuroscience

authors： Bick J,Fox N,Zeanah C,Nelson CA

更新日期：2017-02-07 00:00:00

abstract：:Dysfunction of thalamo-cortical networks involving particularly the thalamic reticular nucleus (TRN) is implicated in schizophrenia. In the neonatal ventral hippocampal lesion (NVHL), a heuristic animal model of schizophrenia, brain oscillation changes similar to those of schizophrenic patients have been reported. The...

journal_title：Neuroscience

authors： Magdaleno-Madrigal VM,Contreras-Murillo G,Camacho-Abrego I,Negrete-Díaz JV,Valdés-Cruz A,Fernández-Mas R,Almazán-Alvarado S,Flores G

更新日期：2017-08-15 00:00:00

abstract：:The subplate (SP) represents a transitory cytoarchitectural fetal compartment containing most subcortical and cortico-cortical afferents, and has a fundamental role in the structural development of the healthy adult brain. There is evidence that schizophrenia and autism may be determined by developmental defects in th...

journal_title：Neuroscience

authors： Serati M,Delvecchio G,Orsenigo G,Mandolini GM,Lazzaretti M,Scola E,Triulzi F,Brambilla P

更新日期：2019-06-01 00:00:00

abstract：:Growth-associated protein-43, an established marker of neuronal plasticity during development and in injury, was used to characterize innervation in the normal human pancreas and changes in chronic alcohol-induced pancreatitis by using light microscopic immunocytochemistry and computer-assisted image analysis. Immunos...

journal_title：Neuroscience

authors： Fink T,Di Sebastiano P,Büchler M,Beger HG,Weihe E

更新日期：1994-11-01 00:00:00

abstract：:The disturbance of the insulin-signaling pathway plays an important role in Alzheimer's disease. Resistance to insulin signaling renders neurons energy-deficient and vulnerable to oxidization or other metabolic insults and impairs synaptic plasticity. In search of neuroprotective drugs, we synthesized a peptide analog...

journal_title：Neuroscience

authors： Wang P,Jiang S,Cui Y,Yue Z,Su C,Sun J,Sheng S,Tian J

更新日期：2011-01-26 00:00:00

abstract：:The location of sympathetic preganglionic neurons (SPN) in the spinal cord of the reeler mouse mutant is abnormal. Instead of their normal location in the intermediolateral column, the majority of SPN in the reeler cluster around the central canal. To determine whether ectopically located SPN in the reeler form approp...

journal_title：Neuroscience

authors： Yip YP,Rinaman L,Capriotti C,Yip JW

更新日期：2003-01-01 00:00:00

abstract：:The involvement of nitric oxide in neurodegenerative processes still remains incompletely characterized. Although nitric oxide has been reported to be an important mediator in neuronal degeneration in different models of cell death involving NMDA-receptor activation, increasing evidence for protective mechanisms has b...

journal_title：Neuroscience

authors： Lautenschlager M,Onufriev MV,Gulyaeva NV,Harms C,Freyer D,Sehmsdorf U,Ruscher K,Moiseeva YV,Arnswald A,Victorov I,Dirnagl U,Weber JR,Hörtnagl H

更新日期：2000-01-01 00:00:00

abstract：:The neurotensin/neuromedin N precursor molecule possesses four lysine-arginine dibasic residues which represent potential sites of cleavage by proteolytic maturation enzymes. As shown in the preceding paper, all of these dibasic residues are cleaved to a variable extent in rat brain. The aim of the present study was t...

journal_title：Neuroscience

authors： Woulfe J,Lafortune L,de Nadai F,Kitabgi P,Beaudet A

更新日期：1994-05-01 00:00:00

abstract：:Electric current has been used for epilepsy treatment by targeting specific neural circuitries. Despite its success, direct contact between the electrode and tissue could cause side effects including pain, inflammation, and adverse biological reactions. Magnetic stimulation overcomes these limitations by offering adva...

journal_title：Neuroscience

authors： Ye H,Chen VC,Helon J,Apostolopoulos N

更新日期：2020-04-15 00:00:00

abstract：:A combined Golgi-electron microscope method was used to study the ultrastructural maturation of synapses on identified pyramidal and multipolar non-pyramidal neurons in the visual cortex of young and adult rabbits. In samples of 10 (time of eye opening), 14, 20 day old and 7 month old animals, fully impregnated pyrami...

journal_title：Neuroscience

authors： Müller LJ,Pattiselanno A,Nunes Cardozo B,Vrensen G

更新日期：1984-08-01 00:00:00

abstract：:Tenascin-C is an extracellular matrix glycoprotein involved in cell adhesion and migration, and neurite outgrowth. Since these processes have been found to be under thyroid control in the developing rat brain, we have investigated the effect of congenital hypothyroidism on tenascin-C expression. At birth, in situ hybr...

journal_title：Neuroscience

authors： Alvarez-Dolado M,González-Sancho JM,Bernal J,Muñoz A

更新日期：1998-05-01 00:00:00

abstract：:It is commonly recognized that physical exercise positively affects several CNS regions and improves cognitive abilities. For example, exercise is associated with an increase in neurogenesis and facilitation of long-term potentiation in the hippocampus. Conversely, animal models for depression are associated with a de...

journal_title：Neuroscience

authors： Dahlin E,Andersson M,Thorén A,Hanse E,Seth H

更新日期：2019-06-01 00:00:00

abstract：:Microdialysis was combined with a highly sensitive sequential multiple antigen radioimmunoassay to simultaneously measure extracellular cholecystokinin and neurotensin fragments from discrete regions of the rat brain in vivo. The assay was conducted in 96-well plates and provided a limit of detection for both peptides...

journal_title：Neuroscience

authors： Maidment NT,Siddall BJ,Rudolph VR,Erdelyi E,Evans CJ

更新日期：1991-01-01 00:00:00

abstract：:The synaptic strength between primary afferent Adelta-fibers, many of which convey pain-related information, and second order neurons in the spinal dorsal horn can be depressed for prolonged periods of time in a use- and N-methyl-D-aspartate receptor-dependent fashion. Here, we have used a transverse spinal cord slice...

journal_title：Neuroscience

authors： Chen J,Sandkühler J

更新日期：2000-01-01 00:00:00