Thyroid neoplasia in children.

Abstract:

:In 1995, the incidence of childhood thyroid cancer in England and Wales was only 0.5 cases per million children per year. Papillary cancers in younger children were histologically distinct from tumors in older individuals. The incidence of thyroid cancer in the vicinity of Chernobyl increased by 62 times within 5 years of the nuclear explosion. Mutations of the RET protooncogene (a growth factor receptor) occur in nearly all familial medullary thyroid carcinomas and may be used for family screening. RET is involved in chromosomal rearrangements in a majority of childhood papillary thyroid cancers. Fine-needle aspiration biopsy identifies the childhood thyroid nodules that are at greatest risk for cancer. It should be noted, however, that approximately 2% of aspirates are falsely negative. The adequacy of unilateral surgery for papillary thyroid cancers is controversial. Aggressive surgery for persistent medullary carcinoma produces remission in one third of patients. Novel radionuclide techniques are useful in detecting and treating metastatic medullary carcinoma.

journal_name

Curr Opin Pediatr

authors

Zimmerman D

doi

10.1097/00008480-199708000-00017

subject

Has Abstract

pub_date

1997-08-01 00:00:00

pages

413-8

issue

4

eissn

1040-8703

issn

1531-698X

journal_volume

9

pub_type

杂志文章,评审
  • Selective mutism.

    abstract:PURPOSE OF REVIEW:Selective mutism is a disorder in which an individual fails to speak in certain social situations though speaks normally in other settings. Most commonly, this disorder initially manifests when children fail to speak in school. Selective mutism results in significant social and academic impairment in ...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0000000000000300

    authors: Hua A,Major N

    更新日期:2016-02-01 00:00:00

  • Disorders of cerebellar growth and development.

    abstract:PURPOSE OF REVIEW:This review summarizes for the pediatrician the current understanding of normal cerebellar and brainstem development, and then discusses selected malformations to highlight advances in the area. The impact of prematurity on cerebellar growth and development is then examined. The important insights pro...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e32801080e8

    authors: Limperopoulos C,du Plessis AJ

    更新日期:2006-12-01 00:00:00

  • Room air or 100% oxygen for resuscitation of infants with perinatal depression.

    abstract:PURPOSE OF REVIEW:The International Liaison Committee on Resuscitation (ILCOR) recommends initiating neonatal resuscitation with concentrations of oxygen between 21 and 100%. This wide range of oxygen concentrations recommended for resuscitation highlights the lack of evidence supporting either 21 or 100% O2. The purpo...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e32832925b8

    authors: Ten VS,Matsiukevich D

    更新日期:2009-04-01 00:00:00

  • Advances in overgrowth syndromes: clinical classification to molecular delineation in Sotos syndrome and Beckwith-Wiedemann syndrome.

    abstract:PURPOSE OF REVIEW:The clinical importance of overgrowth syndromes in the pediatric patient population has been increasingly recognized during the past decade, but clinical overlap among overgrowth syndromes often makes diagnostic categorization difficult. Advances in the molecular delineation of overgrowth syndromes in...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/01.mop.0000187191.74295.97

    authors: Cytrynbaum CS,Smith AC,Rubin T,Weksberg R

    更新日期:2005-12-01 00:00:00

  • Prenatal genetic screening and diagnosis for pediatricians.

    abstract:PURPOSE OF REVIEW:Prenatal genetic screening and diagnostic testing can identify many disorders that will require specialized newborn care and follow-up. Pediatricians should be aware of recent advances in testing that may have implications for their patients and families. RECENT FINDINGS:Over the last half decade, th...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e32833f5f6e

    authors: Cunniff C,Hudgins L

    更新日期:2010-12-01 00:00:00

  • Recent advances in understanding the neural bases of autism spectrum disorder.

    abstract:PURPOSE OF REVIEW:This article reviews current work investigating the neural bases of autism spectrum disorder (ASD) within the discipline of electrophysiological brain research. The manuscript focuses primarily on advances in understanding related to social information processing and interconnectivity among brain syst...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e32834cb9c9

    authors: McPartland JC,Coffman M,Pelphrey KA

    更新日期:2011-12-01 00:00:00

  • 2014 update on atopic dermatitis in children.

    abstract:PURPOSE OF REVIEW:The prevalence of pediatric atopic dermatitis (AD) has increased throughout the world, now ranging from 10 to 20% in developed countries. Pediatric patients with AD make up a substantial proportion of patients seen by general pediatricians, allergists, dermatologists, and other specialists. As such, t...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0000000000000109

    authors: Totri CR,Diaz L,Eichenfield LF

    更新日期:2014-08-01 00:00:00

  • Caring for survivors of childhood cancer: it takes a village.

    abstract:PURPOSE OF REVIEW:Over 80% of children diagnosed with cancer are now cured. The burgeoning population of survivors of childhood cancer experiences high rates of morbidity and mortality due to 'late-effects' of treatment. These can be defined as any consequence of treatment that persists beyond or develops after the com...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0000000000000681

    authors: Song A,Fish JD

    更新日期:2018-12-01 00:00:00

  • Attention-deficit hyperactivity disorder in children.

    abstract::Attention-deficit hyperactivity disorder has been redefined in the classifications in the International Classification of Disease, 10th revision and Diagnostic and Statistical Manual of Mental Disorders, fourth edition. The definitions are more concordant than their predecessors and reemphasize the distinction between...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-199508000-00007

    authors: Baxter PS

    更新日期:1995-08-01 00:00:00

  • Orthopedic aspects of neuromuscular disorders in children.

    abstract::Studies using movement analysis confirm that multiple soft tissue releases improve function in the ambulant child with cerebral palsy, and highlight the fine adjustments of ankle-foot orthosis, which benefit children with myelomeningocele. For both of these disorders, there is information with regard to hip subluxatio...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-199306000-00023

    authors: Roberts A,Evans GA

    更新日期:1993-06-01 00:00:00

  • Rotavirus infection and prevention.

    abstract::The major advance in knowledge about rotavirus infection and prevention has been in vaccine development. Several large studies of tetravalent rhesis rotavirus vaccine have had encouraging results, and a first-generation vaccine is likely to be licensed by the 25th anniversary of the discovery of rotavirus (in 1973). E...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-199702000-00006

    authors: Barnes GL,Bishop RF

    更新日期:1997-02-01 00:00:00

  • Nonoperative management of appendicitis in children.

    abstract:PURPOSE OF REVIEW:The aim of this review is to summarize the recent literature investigating nonoperative management of uncomplicated and complicated appendicitis and highlight recent data establishing its safety and efficacy. RECENT FINDINGS:Recent studies and clinical trials have demonstrated the efficacy of nonoper...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0000000000000487

    authors: López JJ,Deans KJ,Minneci PC

    更新日期:2017-06-01 00:00:00

  • Evaluation of hypertension by the general pediatrician.

    abstract:PURPOSE OF REVIEW:To summarize the recommended work-up in a child who presents with elevated blood pressure as well as innovative evaluation techniques under development. RECENT FINDINGS:'The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents' contains several ...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e328013f647

    authors: Nguyen M,Mitsnefes M

    更新日期:2007-04-01 00:00:00

  • Strategies to improve antibiotic use in the neonatal ICU.

    abstract:PURPOSE OF REVIEW:Neonates are at a high risk of infection and may have nonspecific signs of sepsis. Accordingly, they are heavily exposed to antimicrobials. Neonates are also uniquely at risk of both short-term and long-term complications from antibiotic exposure. This review discusses advances in antibiotic stewardsh...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0000000000000716

    authors: Willis Z,de St Maurice A

    更新日期:2019-02-01 00:00:00

  • Update on child maltreatment.

    abstract:PURPOSE OF REVIEW:Recent literature regarding assessment, management and prevention of child maltreatment will be considered. Unexplained infant and child death will also be reviewed. RECENT FINDINGS:Controversies in the evaluation of unexpected infant death and inflicted traumatic brain injury are ongoing. Evidence c...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e32809f9543

    authors: Newton AW,Vandeven AM

    更新日期:2007-04-01 00:00:00

  • Blunt cervical spine injury in children.

    abstract:PURPOSE OF REVIEW:We present data from recently conducted research regarding the diagnosis of blunt cervical spine injury (CSI) in children. RECENT FINDINGS:Research in the prehospital setting to evaluate the need for cervical spine immobilization in children, regardless of clinical findings or mechanism of injury, su...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e3283527035

    authors: Tilt L,Babineau J,Fenster D,Ahmad F,Roskind CG

    更新日期:2012-06-01 00:00:00

  • Strength training and nutritional supplement use in adolescents.

    abstract::The "win at all costs" mentality is becoming increasingly common in youth sports, and young athletes are often looking for methods to improve sports performance and avoid injury. As organized sports participation continues to increase among American adolescents, questions related to sports medicine are more frequently...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-199908000-00004

    authors: Metzl JD

    更新日期:1999-08-01 00:00:00

  • Rotavirus vaccines: an update.

    abstract:PURPOSE OF REVIEW:Rotavirus infection is the most common cause of severe diarrhea disease in infants and young children worldwide and has a major global impact on childhood morbidity and mortality. Vaccination is the only control measure likely to have a significant impact on the incidence of severe dehydrating rotavir...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/01.mop.0000147907.30720.04

    authors: Dennehy PH

    更新日期:2005-02-01 00:00:00

  • The Internet as an adjunct for pediatric primary care.

    abstract:PURPOSE OF REVIEW:This review highlights recent publications on the use of the Internet as it relates to pediatric primary care, including its application to the pediatrician, teen, pediatric patient, and patients' parents. A brief overview of early work is introduced. RECENT FINDINGS:The Internet has become a tool to...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e328331e7b4

    authors: Kind T

    更新日期:2009-12-01 00:00:00

  • Cutaneous bacterial infections in the newborn.

    abstract:PURPOSE OF REVIEW:This review examines neonatal bacterial skin infections with respect to host immunity, bacterial pathogens, patterns of infection, and new therapeutic approaches. RECENT FINDINGS:Advances have been made in our understanding of innate host defense and the emerging role of cutaneous antimicrobial pepti...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/01.mop.0000171321.68806.bd

    authors: Larson AA,Dinulos JG

    更新日期:2005-08-01 00:00:00

  • Atopic diseases and upper respiratory infections.

    abstract::This article reviews information on the topics of asthma, atopic dermatitis, food allergy, and upper respiratory infections. The asthma section provides an in-depth look at sociodemographic factors contributing to asthma morbidity and the barriers to asthma control. New findings on the triggers and therapies of atopic...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-200010000-00018

    authors: Lester MR,Schneider LC

    更新日期:2000-10-01 00:00:00

  • Cerebral palsy.

    abstract::Cerebral palsy is caused by a static lesion to the cerebral motor cortex that is acquired before, at, or within 5 years of birth. Multiple causes for the condition exist and include cerebral anoxia, cerebral hemorrhage, infection, and genetic syndromes. Cerebral palsy is commonly classified according to the type of mo...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-199702000-00017

    authors: Dabney KW,Lipton GE,Miller F

    更新日期:1997-02-01 00:00:00

  • Stachybotrys.

    abstract::Stachybotrys is a toxin-producing fungus that grows indoors when both water and cellulose are available. Epidemiologic evidence has demonstrated an association between acute pulmonary hemorrhage in infants and exposure to Stachybotrys and other fungi in water-damaged home environments. In recent years, advances in und...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-200302000-00017

    authors: Etzel RA

    更新日期:2003-02-01 00:00:00

  • Folate protection from congenital heart defects linked with canonical Wnt signaling and epigenetics.

    abstract:PURPOSE OF REVIEW:Environmental factors, such as drugs, chemicals, or abnormal concentrations of natural metabolites, induce birth defects. Environmental effects on cardiogenesis have been little studied in contrast to neurogenesis. This review presents evidence on three environmental factors: alcohol, the drug lithium...

    journal_title:Current opinion in pediatrics

    pub_type: 社论,评审

    doi:10.1097/MOP.0b013e32833e2723

    authors: Linask KK,Huhta J

    更新日期:2010-10-01 00:00:00

  • Novel initiatives of the National Institutes of Health to support congenital heart disease research.

    abstract:PURPOSE OF REVIEW:In fiscally challenging times, scientists must seek creative strategies and leverage existing resources to advance research. RECENT FINDINGS:This review describes programmes supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to promote resear...

    journal_title:Current opinion in pediatrics

    pub_type: 历史文章,杂志文章,评审

    doi:10.1097/MOP.0b013e328364b8a7

    authors: Burns KM,Pearson GD,Kaltman JR

    更新日期:2013-10-01 00:00:00

  • Pediatric anesthesia and sedation.

    abstract::Advances in pediatric anesthesia can contribute to improved care of children in other environments. As an example, drugs and dosages established in preoperative sedation of children provide a base for their application in sedation and pain relief of children undergoing painful procedures in the emergency unit, oncolog...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-199306000-00011

    authors: Broennle AM,Cohen DE

    更新日期:1993-06-01 00:00:00

  • Pearls, perils, and pitfalls in the assessment and treatment of attention-deficit/hyperactivity disorder in adolescents.

    abstract:PURPOSE OF REVIEW:To provide clinicians with an updated overview of key considerations related to the clinical assessment and management of attention-deficit/hyperactivity disorder (ADHD) in adolescents. RECENT FINDINGS:The American Psychiatric Association's recently revised Diagnostic and Statistical Manual of Mental...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0000000000000053

    authors: Obioha O,Adesman A

    更新日期:2014-02-01 00:00:00

  • Aquaporin molecular biology and clinical abnormalities of the water transport channels.

    abstract::In the past year, significant progress has been achieved in the research on aquaporins (AQPs), a family of structurally related molecular water channels. Three novel AQPs were identified, giving a total of ten mammalian AQPs. An important step forward in identifying the aqueous pore in AQP molecules was the determinat...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/00008480-199808000-00018

    authors: Knoers NV,Deen PM

    更新日期:1998-08-01 00:00:00

  • Genetic discoveries and treatment advances in neuroblastoma.

    abstract:PURPOSE OF REVIEW:Major advances in our understanding of the genetic basis of neuroblastoma, and the role somatic alterations play in driving tumor growth, have led to improvements in risk-stratified therapy and have provided the rationale for targeted therapies. In this review, we highlight current risk-based treatmen...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0000000000000296

    authors: Bagatell R,Cohn SL

    更新日期:2016-02-01 00:00:00

  • New developments in the treatment of pediatric hemophilia and bleeding disorders.

    abstract:PURPOSE OF REVIEW:Disorders of hemostasis such as hemophilia, von Willebrand disease (VWD), and other clotting protein deficiencies lead to significant morbidity in the pediatric population. Because of the limitations of current treatment options, novel therapies are being developed, many of which are reviewed here. R...

    journal_title:Current opinion in pediatrics

    pub_type: 杂志文章,评审

    doi:10.1097/MOP.0b013e32835bf77e

    authors: Branchford BR,Monahan PE,Di Paola J

    更新日期:2013-02-01 00:00:00