Disorders of cerebellar growth and development.

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe current concepts on inflammation, immunity and insulin resistance. Metabolic and immune systems are closely involved in inflammation and significantly contribute to the pathology seen in the pediatric intensive care unit. The ability of insulin to decrease hep...

journal_title：Current opinion in pediatrics

authors： Dhar A,Castillo L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The International Liaison Committee on Resuscitation (ILCOR) recommends initiating neonatal resuscitation with concentrations of oxygen between 21 and 100%. This wide range of oxygen concentrations recommended for resuscitation highlights the lack of evidence supporting either 21 or 100% O2. The purpo...

journal_title：Current opinion in pediatrics

authors： Ten VS,Matsiukevich D

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The management of displaced medial humeral epicondyle fractures in children remains controversial. The indications for surgery, the ideal surgical strategy and the implications of a painful nonunion remain unclear. RECENT FINDINGS:This article describes the state of the evidence and the art in the ma...

journal_title：Current opinion in pediatrics

authors： Firth AM,Marson BA,Hunter JB

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Sepsis is the leading cause of pediatric death worldwide. In the United States alone, there are 72 000 children hospitalized for sepsis annually with a reported mortality rate of 25% and an economic cost estimated to be $4.8 billion. However, it is only recently that the definition and management of p...

journal_title：Current opinion in pediatrics

authors： Mathias B,Mira JC,Larson SD

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic nephrotic syndrome in children is commonly associated with minimal change disease and response to steroid therapy. Steroid-unresponsive nephrotic syndrome is often characterized by persistent proteinuria and progression to chronic kidney disease. Focal segmental glomerulosclerosis is the le...

journal_title：Current opinion in pediatrics

authors： Del Rio M,Kaskel F

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Describe developments in the etiological understanding of Tourette syndrome. RECENT FINDINGS:Tourette syndrome is a complex heterogenous clinical syndrome, which is not a unitary entity. Pathophysiological models describe gamma-aminobutyric acid-ergic-associated disinhibition of cortico-basal ganglia...

journal_title：Current opinion in pediatrics

authors： Dale RC

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Juvenile myasthenia gravis is a relatively rare autoimmune neuromuscular disorder. The pathophysiology of juvenile myasthenia gravis is similar to that of adult myasthenia gravis, though there remain important differences regarding presentation and therapeutic options. We review the pathophysiology, c...

journal_title：Current opinion in pediatrics

authors： Liew WK,Kang PB

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In fiscally challenging times, scientists must seek creative strategies and leverage existing resources to advance research. RECENT FINDINGS:This review describes programmes supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to promote resear...

journal_title：Current opinion in pediatrics

authors： Burns KM,Pearson GD,Kaltman JR

更新日期：2013-10-01 00:00:00

abstract：:Bone marrow transplantation has become well established in the treatment of malignant and nonmalignant disorders. Steady progress continues in improving survival after transplantation, but many problems remain to be solved. Relapsed disease is a major limitation, and new, more intensive preparative regimens are being ...

journal_title：Current opinion in pediatrics

authors： Robertson KA

更新日期：1993-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Considerable attention has recently been focused on the pathogenesis, diagnosis and treatment of osteogenesis imperfecta. Two new genes have been defined in patients with recessive severe or lethal osteogenesis imperfecta types. Diagnostic concerns involve testing procedures, either skin biopsies or D...

journal_title：Current opinion in pediatrics

authors： Shapiro JR,Sponsellor PD

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize recent research regarding the diagnosis of allergic rashes and to suggest future directions for the promotion of accurate diagnosis and endotype specification. RECENT FINDINGS:Multiple cohort studies demonstrate that with appropriate clinical evaluation, dru...

journal_title：Current opinion in pediatrics

authors： Happel CS

更新日期：2017-06-01 00:00:00

abstract：:A constant in the practice of general pediatrics is an emphasis on infant nutrition and monitoring of growth. These topics are the focus of this issue's "Office pediatrics" section. Much of the new research and publication concerning nutrition in childhood in the past year continues to focus on breastfeeding-its short...

journal_title：Current opinion in pediatrics

authors： Rider E,Samuels R,Wilson K,Homer C

更新日期：1996-06-01 00:00:00

abstract：:Aim of this review is to present the latest advances in the identification of the genetic determinants of intellectual deficiency. Mental retardation (MR) is often associated with other neurologic symptoms, metabolic disorders, or malformation syndromes. The purpose of the review is to subdivide the large field of MR ...

journal_title：Current opinion in pediatrics

authors： Chiurazzi P,Oostra BA

更新日期：2000-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Rotavirus infection is the most common cause of severe diarrhea disease in infants and young children worldwide and has a major global impact on childhood morbidity and mortality. Vaccination is the only control measure likely to have a significant impact on the incidence of severe dehydrating rotavir...

journal_title：Current opinion in pediatrics

authors： Dennehy PH

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Abdominal wall defects comprising both gastroschisis and omphalocele remain a source of significant morbidity and mortality, despite the advances in neonatal and pediatric surgical care. Survival has improved over the past few decades, especially with parenteral nutrition and surgical repair. Yet, sti...

journal_title：Current opinion in pediatrics

authors： Islam S

更新日期：2008-06-01 00:00:00

abstract：:Attention deficit hyperactivity disorder is one of the most common behavioral disorders of childhood and is frequently assessed and treated by pediatricians and other primary care physicians. The diagnosis of attention deficit hyperactivity disorder is based on the careful synthesis of clinical data derived from multi...

journal_title：Current opinion in pediatrics

authors： McGough JJ,McCracken JT

更新日期：2000-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The present coronavirus disease 2019 (COVID-19) pandemic has created additional challenges with an increased number of presumed healthy, full-term newborns being discharged at 24 h after delivery. Short lengths of stay raise the possibility of mother-infant dyads being less ready for discharge, define...

journal_title：Current opinion in pediatrics

authors： Harriel KL,Nolt D,Moore S,Kressly S,Bernstein HH

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Gynecomastia is a common finding in adolescent men. The primary care provider should feel equipped to thoroughly evaluate this condition and to differentiate physiologic from pathologic breast enlargement. The present review focuses on the epidemiology, pathogenesis, evaluation, and treatment of gynec...

journal_title：Current opinion in pediatrics

authors： Nordt CA,DiVasta AD

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Epidermolysis bullosa is a hereditary skin disorder characterized by skin fragility. However, the disease can manifest in many different organ systems, therefore children born with epidermolysis bullosa may have life long, complex medical needs. In this review, we will use a system-based approach to h...

journal_title：Current opinion in pediatrics

authors： Cohn HI,Teng JM

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Physical activity has been highlighted internationally as a beneficial intervention for weight control and the improvement of physical and mental health. This review highlights findings from recent literature to guide office-based promotion of physical activity for obesity treatment and prevention. R...

journal_title：Current opinion in pediatrics

authors： Floriani V,Kennedy C

更新日期：2007-02-01 00:00:00

abstract：:The development of the attachment behavioral system in infancy has been the focus of a wide range of research in the past 30 years. The clinical significance of disturbances in this area of development is currently a major focus for this research. Research on patterns of attachment in infancy has informed understandin...

journal_title：Current opinion in pediatrics

authors： Boris NW,Zeanah CH

更新日期：1998-08-01 00:00:00

abstract：:Genetic causes account for 20% to 25% of human birth defects, but the largest proportion of birth defects have no definitive etiology and some of these malformations may be due to intrinsic, "nonpreventable" spontaneous errors of development. Environmental causes, which include maternal disease states, maternal infect...

journal_title：Current opinion in pediatrics

authors： Brent RL,Beckman DA,Landel CP

更新日期：1993-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this review is to provide updates on the evolution of conceptual definitions as they relate to quality in healthcare, existing measurement platforms for performance benchmarking in pediatric surgery, and available tools for quality improvement that are relevant to care of the pediatric sur...

journal_title：Current opinion in pediatrics

authors： Cameron DB,Rangel SJ

更新日期：2016-06-01 00:00:00

abstract：:The importance of pediatric interhospital transport has increased dramatically in the past 5 to 10 years. Reasons include improved capabilities of tertiary care centers receiving transported patients, advances in availability of portable equipment that functions well in moving vehicles, and widespread recognition that...

journal_title：Current opinion in pediatrics

authors： McCloskey KA

更新日期：1996-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Patient education is an essential component of asthma management. The current paradigm of asthma education has moved away from the 'information-transfer' programmes that characterized earlier approaches and that were shown to be largely ineffective, to approaches that promote self-management education...

journal_title：Current opinion in pediatrics

authors： Shah S,Roydhouse JK,Sawyer SM

更新日期：2008-12-01 00:00:00

abstract：:Over the past several years, many new strategies have evolved for improving the care of patients with acute lung injury and respiratory failure. Although many of these new modalities remain unproven, some show much promise for decreasing the morbidity and mortality seen in critically ill patients who need assisted ven...

journal_title：Current opinion in pediatrics

authors： Donnelly KM,Bogue CW

更新日期：1998-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The interstitial lung diseases are a heterogeneous group of rare disorders of largely unknown etiology. The occurrence of familial cases of pediatric interstitial lung diseases with the onset of symptoms developing early in infancy has suggested a genetic basis for some forms of interstitial lung dise...

journal_title：Current opinion in pediatrics

authors： Nogee LM

更新日期：2006-06-01 00:00:00

abstract：:Complete deficiency of one of the early components (C1, C4, or C2) of the classical pathway of the complement cascade is one of the strongest genetic risk factors for systemic lupus erythematosus that has been recognized. The lupus that occurs in complement-deficient individuals typically presents in early childhood. ...

journal_title：Current opinion in pediatrics

authors： Sullivan KE

更新日期：1998-12-01 00:00:00

abstract：:The use of extracorporeal techniques for the treatment of pediatric diseases has expanded dramatically in the past decade. During this time, experience with both plasmapheresis and renal replacement therapy has become commonplace in ICUs and nephrology programs throughout the world. The indications for these therapies...

journal_title：Current opinion in pediatrics

authors： Bunchman TE

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:We provide an overview of the past year's literature on congenital heart surgery. RECENT FINDINGS:This review focuses on selected disease entities, operative techniques, perioperative management strategies, and quality of care. SUMMARY:Congenital heart surgery is an evolving field. ...

journal_title：Current opinion in pediatrics

authors： Welke KF,Komanapalli C,Shen I,Ungerleider RM

更新日期：2005-10-01 00:00:00