Pediatric sepsis.

abstract：PURPOSE OF REVIEW:A second-generation 13-valent pneumococcal conjugate vaccine (PCV13) was licensed and recommended for universal immunization of children through age 5 years in 2010. Its introduction is intended to address the residual burden of pneumococcal diseases that persists a decade after the introduction of PC...

journal_title：Current opinion in pediatrics

authors： Grijalva CG,Pelton SI

更新日期：2011-02-01 00:00:00

abstract：:Major advances in the genetic understanding of the limb-girdle (LGMD) and congenital (CMD) muscular dystrophies have led to a new, genetically based classification of these disorders. The definition of the complex of dystrophin-associated proteins on a biochemical and subsequently genetic level has greatly accelerated...

journal_title：Current opinion in pediatrics

authors： Bönnemann CG,McNally EM,Kunkel LM

更新日期：1996-12-01 00:00:00

abstract：:Developmental care is a framework that encompasses all care procedures as well as social and physical aspects in the newborn intensive care unit. Its goal is to support each individual infant to be as stable, well-organized, and competent as possible. The infant's physiologic and behavioral expression of current funct...

journal_title：Current opinion in pediatrics

authors： Als H

更新日期：1998-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Abdominal wall defects comprising both gastroschisis and omphalocele remain a source of significant morbidity and mortality, despite the advances in neonatal and pediatric surgical care. Survival has improved over the past few decades, especially with parenteral nutrition and surgical repair. Yet, sti...

journal_title：Current opinion in pediatrics

authors： Islam S

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Environmental factors, such as drugs, chemicals, or abnormal concentrations of natural metabolites, induce birth defects. Environmental effects on cardiogenesis have been little studied in contrast to neurogenesis. This review presents evidence on three environmental factors: alcohol, the drug lithium...

journal_title：Current opinion in pediatrics

authors： Linask KK,Huhta J

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To illustrate potential risks and benefits of disease screening for newborns using the example of Duchenne muscular dystrophy. RECENT FINDINGS:There is a wide range in the reported positive predictive value for screening male newborns for Duchenne muscular dystrophy by the creatine kinase level on dr...

journal_title：Current opinion in pediatrics

authors： Kemper AR,Wake MA

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Lyme disease, caused by Borrelia burgdorferi, is the most common vector-borne illness in the United States. The pathogenesis, ecology, and epidemiology of Lyme disease have been well described, and antimicrobial treatment is very effective. There has been controversy about whether infection can persis...

journal_title：Current opinion in pediatrics

authors： Oliveira CR,Shapiro ED

更新日期：2015-02-01 00:00:00

abstract：:Medical informatics is both a science, which seeks to understand the information requirements of medical practice, research, and education, and an engineering discipline, which applies new technologies to help manage the explosion of data and new knowledge that confront contemporary physicians. Computerization of the ...

journal_title：Current opinion in pediatrics

authors： Shiffman RN

更新日期：1994-10-01 00:00:00

abstract：:Injury is our children's greatest health problem, and pediatricians will frequently see finger and hand injuries in the office and emergency room. Many of these will be fingertip crush injuries, which are quite common in toddlers and are often undertreated. Pediatric finger and wrist fractures and sprains generally do...

journal_title：Current opinion in pediatrics

authors： Innis PC

更新日期：1995-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Advances in the field of pediatric nutrition continue to help the pediatric office practitioner provide excellent clinical care to their patients. In 2003, several important papers were published in the field of clinical nutrition that are reviewed. RECENT FINDINGS:New recommendations by the American...

journal_title：Current opinion in pediatrics

authors： Collier S,Fulhan J,Duggan C

更新日期：2004-06-01 00:00:00

abstract：:In the recent past, we have seen novel information on the bidirectional interactions between the endocrine and immune systems. Thus, the central nervous system, through the hypothalamic-pituitary-adrenal axis and the peripheral autonomic and sensory systems, influences the quantity and the quality of the immune and in...

journal_title：Current opinion in pediatrics

authors： Papanicolaou DA,Chrousos GP

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The number of pediatric cancer survivors is growing rapidly as treatments become more effective. However, many current regimens cause gonadotoxicity and permanent infertility, significantly impacting quality of life. The purpose of this review is to update pediatric oncologists on risk factors for can...

journal_title：Current opinion in pediatrics

authors： Ginsberg JP

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Childhood malnutrition is a major global health issue. It is often thought of as a developing world problem and therefore, underdiagnosed or misdiagnosed in developed countries. The delay in diagnosis and treatment can lead to increased morbidity and mortality. Cutaneous manifestations are often the i...

journal_title：Current opinion in pediatrics

authors： Lekwuttikarn R,Teng JMC

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This study reviews the history of neonatal drug development, recent legislative efforts designed to facilitate the study of therapeutic agents in neonates, and future steps necessary to advance drug development. RECENT FINDINGS:Although many federal regulations have been introduced over the past 15 y...

journal_title：Current opinion in pediatrics

authors： Smith AM,Davis JM

更新日期：2017-04-01 00:00:00

abstract：:In the past decade a number of studies have systematically addressed the questions that existed regarding optimal ways to rehydrate and then refeed infants and children with diarrhea. Two very thorough papers are the highlights of the past year's publications in the topic of acute gastroenteritis in children. One summ...

journal_title：Current opinion in pediatrics

authors： Lifschitz CH

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews three common abnormalities requiring surgical treatment in adults with congenital heart disease (CHD): Ebstein's anomaly, the failing Fontan, and pulmonary valve disease. RECENT FINDINGS:As of 2000, more adults than children are alive with CHD. Each year, more of these adults wit...

journal_title：Current opinion in pediatrics

authors： Dearani JA,Mavroudis C,Quintessenza J,Deal BJ,Backer CL,Fitzgerald P,Connolly HM,Jacobs JP

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This study will outline recent advances in echocardiography and their impact in the understanding of cardiac morphology and ventricular function. RECENT FINDINGS:Evaluation of morphologic abnormalities in pediatric cardiology has benefited greatly from three-dimensional echocardiography, particularly...

journal_title：Current opinion in pediatrics

authors： Lopez L

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to provide primary care physicians with updates on recent literature regarding clubfoot and answer questions asked by parents and caregivers of children with clubfoot. The topics discussed include prenatal counseling, relapse after Ponseti treatment, long-term outcomes following succe...

journal_title：Current opinion in pediatrics

authors： Yau A,Doyle SM

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This update explores the current management options for adolescent obesity with a specific focus on bariatric surgery. RECENT FINDINGS:Research has highlighted the serious health complications associated with adolescent obesity and thus emphasized the need for effective interventions. With the increa...

journal_title：Current opinion in pediatrics

authors： McGinty S,Richmond TK,Desai NK

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a current review of recent publications with regards to intracranial hypertension. RECENT FINDINGS:Attempts were made to provide pediatric data; however, the recent completion of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) has provided a wealth of data with regards to ...

journal_title：Current opinion in pediatrics

authors： Jordan CO,Aylward SC

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite improvements in surgical techniques, valvular regurgitation results in major morbidity in children with heart disease. Functional anatomy, mechanisms of valve closure and adaptation to changing hemodynamic stress in normal mitral and tricuspid valves are complex and only partially understood. ...

journal_title：Current opinion in pediatrics

authors： Khoo NS,Smallhorn JF

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has become increasingly important as a cause of skin and soft tissue infections (SSTIs), particularly abscesses, in patients seen in the emergency department setting. The antibiotic sensitivity profile of Staphylococcus aureus ...

journal_title：Current opinion in pediatrics

authors： Odell CA

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The literature was reviewed to describe the role of gait analysis in the orthopaedic management of ambulatory children with cerebral palsy and examine the current best evidence to support these roles. RECENT FINDINGS:Gait laboratory analysis is superior to visual or observational analysis of gait bec...

journal_title：Current opinion in pediatrics

authors： Narayanan UG

更新日期：2007-02-01 00:00:00

abstract：:Bone marrow transplantation has become well established in the treatment of malignant and nonmalignant disorders. Steady progress continues in improving survival after transplantation, but many problems remain to be solved. Relapsed disease is a major limitation, and new, more intensive preparative regimens are being ...

journal_title：Current opinion in pediatrics

authors： Robertson KA

更新日期：1993-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Inherited disorders of calcium and phosphate homeostasis have variable presentation and can cause significant morbidity. An understanding of the mode of inheritance and pathophysiology of these conditions will help in the diagnosis and early institution of therapy. RECENT FINDINGS:Identification of g...

journal_title：Current opinion in pediatrics

authors： Gattineni J

更新日期：2014-04-01 00:00:00

abstract：:von Willebrand disease (VWD) is a bleeding disorder caused by quantitative (type 1 and 3) or qualitative (type 2) defects of von Willebrand factor (VWF). The mechanisms of most inherited VWD types have been recently elucidated by genetic and molecular diagnosis, but the phenotypic tests based on measurements of plasma...

journal_title：Current opinion in pediatrics

authors： Federici AB,Mannucci PM

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight studies that have contributed significantly to our current knowledge of inhaled glucocorticoids in childhood asthma. RECENT FINDINGS:In 2006, three important studies were published that investigated whether inhaled glucocorticoid therapy, if started soon after the onset of asthma symptom...

journal_title：Current opinion in pediatrics

authors： Spahn JD,Szefler SJ

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Radiation exposure from computed tomography is associated with a small but significant increase in risk for fatal cancer over a child's lifetime. This review aims to heighten awareness and spearhead efforts to reduce unnecessary computed tomography scans in children. RECENT FINDINGS:The use of pediat...

journal_title：Current opinion in pediatrics

authors： Shah NB,Platt SL

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will focus on therapeutic considerations and recent advances in treatment of caustic ingestion injuries. RECENT FINDINGS:A retrospective study suggests that it may be safe to advance the endoscope beyond the first circumferential burn to allow for a more complete assessment of extent of i...

journal_title：Current opinion in pediatrics

authors： Shub MD

更新日期：2015-10-01 00:00:00

abstract：:Autoimmune Lymphoproliferative Syndrome (ALPS) is a recently recognized disease in which a genetic defect in programmed cell death, or apoptosis, leads to breakdown of lymphocyte homeostasis and normal immunologic tolerance. Some authors have referred to ALPS as Canale-Smith syndrome or lymphoproliferative syndrome wi...

journal_title：Current opinion in pediatrics

authors： Jackson CE,Puck JM

更新日期：1999-12-01 00:00:00