Informatics and general pediatrics.

abstract：PURPOSE OF REVIEW:This review will outline the screening, diagnosis and management of cystic fibrosis related diabetes (CFRD). It will also discuss advances in the detection of early glucose abnormalities, their clinical significance and the emerging role for early insulin therapy. RECENT FINDINGS:Before the onset of ...

journal_title：Current opinion in pediatrics

authors： Hameed S,Jaffé A,Verge CF

更新日期：2015-08-01 00:00:00

abstract：:Large and unusually large von Willebrand factor (vWf) multimers may be responsible for systemic platelet aggregation in thrombotic thrombocytopenic purpura (TTP). This possibility is supported by studies that show deficient vWf-cleaving metalloproteinase and increased platelet-vWf binding during TTP episodes. In acute...

journal_title：Current opinion in pediatrics

authors： Baker KR,Moake JL

更新日期：2000-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The number of pediatric cancer survivors is growing rapidly as treatments become more effective. However, many current regimens cause gonadotoxicity and permanent infertility, significantly impacting quality of life. The purpose of this review is to update pediatric oncologists on risk factors for can...

journal_title：Current opinion in pediatrics

authors： Ginsberg JP

更新日期：2011-02-01 00:00:00

abstract：:The major advance in knowledge about rotavirus infection and prevention has been in vaccine development. Several large studies of tetravalent rhesis rotavirus vaccine have had encouraging results, and a first-generation vaccine is likely to be licensed by the 25th anniversary of the discovery of rotavirus (in 1973). E...

journal_title：Current opinion in pediatrics

authors： Barnes GL,Bishop RF

更新日期：1997-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The term 'dual diagnosis' most commonly refers to the combination of severe mental illness and substance-use disorder (SUD). It is estimated that 7-10 million people in the USA alone have at a minimum one psychiatric disorder in addition to a SUD. As many of the psychiatric illnesses implicated have t...

journal_title：Current opinion in pediatrics

authors： Santucci K

更新日期：2012-04-01 00:00:00

abstract：:This review summarizes recent literature regarding the clinical and molecular features of nonmalignant leukocyte disorders in children. Leukocyte adhesion deficiency and chronic granulomatous disease, two inherited disorders of neutrophil function, continue to be the best-characterized disorders with respect to specif...

journal_title：Current opinion in pediatrics

authors： Dinauer MC

更新日期：1993-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To illustrate potential risks and benefits of disease screening for newborns using the example of Duchenne muscular dystrophy. RECENT FINDINGS:There is a wide range in the reported positive predictive value for screening male newborns for Duchenne muscular dystrophy by the creatine kinase level on dr...

journal_title：Current opinion in pediatrics

authors： Kemper AR,Wake MA

更新日期：2007-12-01 00:00:00

abstract：:Superior mesenteric artery (SMA) syndrome describes vascular compression of the third portion of the duodenum and presents with nausea, postprandial vomiting, and epigastric abdominal pain. The syndrome is rare and may be missed if appropriate radiologic studies are not performed or the clinical presentation is atypic...

journal_title：Current opinion in pediatrics

authors： Kurbegov A,Grabb B,Bealer J

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To emphasize an exploration of mechanisms of kidney stone disease based on a molecular understanding of excess urinary excretions of calcium, oxalate, cystine, and uric acid. RECENT FINDINGS:Hypercalciuria is discussed relative to mutations in the renal chloride genes CLCN5 and CLCNKB, WNK kinases, A...

journal_title：Current opinion in pediatrics

authors： Langman CB

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Lyme disease, caused by Borrelia burgdorferi, is the most common vector-borne illness in the United States. The pathogenesis, ecology, and epidemiology of Lyme disease have been well described, and antimicrobial treatment is very effective. There has been controversy about whether infection can persis...

journal_title：Current opinion in pediatrics

authors： Oliveira CR,Shapiro ED

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Complement mediated hemolytic uremic syndrome (aHUS) accounts for a significant proportion of non-shiga toxin HUS. The purpose of this review is to outline the pathophysiology, clinical features and therapeutic options for aHUS. RECENT FINDINGS:In the last decade, strides have been made in identifyin...

journal_title：Current opinion in pediatrics

authors： Joseph C,Gattineni J

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Adolescents, in particular those that are most disenfranchised, are increasingly at risk of acquiring HIV and, when acquiring HIV, have worse outcomes than adults. This article reviews the recent approaches to combination prevention aiming to optimize the HIV prevention and HIV treatment continua. RE...

journal_title：Current opinion in pediatrics

authors： Rotheram-Borus MJ,Davis E,Rezai R

更新日期：2018-02-01 00:00:00

abstract：:Neonatal infections range from early-onset vertically acquired infections to nosocomial bacterial sepsis, and they account for significant morbidity and mortality globally. The recent emergence of perinatally acquired HIV-1 infection has also placed an enormous burden on existing meager health resources in developing ...

journal_title：Current opinion in pediatrics

authors： Bhutta ZA

更新日期：1997-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In many United States households, there are many substances used to control the exposure of our children to mosquitoes, mice and rats. This review provides information on common mosquito repellents and rodenticides used in households and discusses their toxicity, in order to help pediatricians better ...

journal_title：Current opinion in pediatrics

authors： Kendrick DB

更新日期：2006-04-01 00:00:00

abstract：:Attention-deficit hyperactivity disorder has been redefined in the classifications in the International Classification of Disease, 10th revision and Diagnostic and Statistical Manual of Mental Disorders, fourth edition. The definitions are more concordant than their predecessors and reemphasize the distinction between...

journal_title：Current opinion in pediatrics

authors： Baxter PS

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will examine the current evidence regarding pediatric blunt abdominal trauma and the physical exam findings, laboratory values, and radiographic imaging associated with the diagnosis of intra-abdominal injuries (IAI), as well as review the current literature on pediatric hollow viscus inju...

journal_title：Current opinion in pediatrics

authors： Schonfeld D,Lee LK

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Children with medical or surgical critical illness or injury require skillful attention to physical, emotional, psychological, and spiritual needs, whereas their families need support and guidance in facing life-threatening or life-changing events and gut-wrenching decisions. This article reviews curr...

journal_title：Current opinion in pediatrics

authors： Rothschild CB,Derrington SF

更新日期：2020-06-01 00:00:00

abstract：:Bacterial meningitis is an important problem in childhood. Vaccines can prevent Haemophilus influenzae type b disease and are being developed for infections caused by meningococci and pneumococci. Lumbar puncture is an important part of the diagnostic workup although care is required with its use. Once meningitis is d...

journal_title：Current opinion in pediatrics

authors： Booy R,Kroll S

更新日期：1994-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Enhanced recovery protocols (ERPs) have been adopted for a variety of adult surgical conditions and resulted in markedly improved outcomes, including decreased length of stays, complications, costs, and narcotic utilization. In this review, we describe the development and implementation of an ERP for ...

journal_title：Current opinion in pediatrics

authors： Raval MV,Heiss KF

更新日期：2018-06-01 00:00:00

abstract：:The insulin-like growht factors (IGFs) are potent mitogenic agents that have been recognized for three decades. Recently, however, the complex milieu in which they operate has begun to be unraveled. Endocrine and autocrine patterns of IGF secretion have been identified and specific receptors that bind IGFs and mediate...

journal_title：Current opinion in pediatrics

authors： Cohen P,Rosenfeld RG

更新日期：1994-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will be covering dysfunctional voiding, its diagnosis, and treatment options. This will focus primarily on dysfunctional voiding rather than all lower urinary tract dysfunction and we will focus on some of the newer findings and progress within this disease. RECENT FINDINGS:Dysfunctional ...

journal_title：Current opinion in pediatrics

authors： Bauer A

更新日期：2020-12-10 00:00:00

abstract：PURPOSE OF REVIEW:Infantile spasms, mental retardation, autism, and dystonia represent disabling diseases for which little etiologic information is available. Mutations in the Aristaless related homeobox gene (ARX) have been found in patients with these conditions. This discovery provides important genetic information ...

journal_title：Current opinion in pediatrics

authors： Sherr EH

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Lung disease in cystic fibrosis (CF) results from chronic airway infection and inflammation leading to progressive bronchiectasis and respiratory failure. Bacterial pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, and Burkholderia cepacia, are known contributors. Recent studies usin...

journal_title：Current opinion in pediatrics

authors： Zemanick ET,Sagel SD,Harris JK

更新日期：2011-06-01 00:00:00

abstract：:In 1995, the incidence of childhood thyroid cancer in England and Wales was only 0.5 cases per million children per year. Papillary cancers in younger children were histologically distinct from tumors in older individuals. The incidence of thyroid cancer in the vicinity of Chernobyl increased by 62 times within 5 year...

journal_title：Current opinion in pediatrics

authors： Zimmerman D

更新日期：1997-08-01 00:00:00

abstract：:Dyslipidemia increases the risk of cardiovascular events among individuals with renal disease, and there is a growing body of evidence that it hastens the progression of renal disease itself. Children with nephrotic syndrome or renal transplants have easily recognized hyperlipidemia. Among those with chronic renal ins...

journal_title：Current opinion in pediatrics

authors： Saland JM,Ginsberg H,Fisher EA

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective mutism is a disorder in which an individual fails to speak in certain social situations though speaks normally in other settings. Most commonly, this disorder initially manifests when children fail to speak in school. Selective mutism results in significant social and academic impairment in ...

journal_title：Current opinion in pediatrics

authors： Hua A,Major N

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Pediatric-onset multiple sclerosis (MS) is increasingly recognized. Conversely, MS diagnosis in the pediatric population continues to be challenging, particularly in the youngest group of patients. An interesting amount of data has been recently published concerning immunopathogenesis, environmental f...

journal_title：Current opinion in pediatrics

authors： Tenembaum SN

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe current concepts on inflammation, immunity and insulin resistance. Metabolic and immune systems are closely involved in inflammation and significantly contribute to the pathology seen in the pediatric intensive care unit. The ability of insulin to decrease hep...

journal_title：Current opinion in pediatrics

authors： Dhar A,Castillo L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will focus on therapeutic considerations and recent advances in treatment of caustic ingestion injuries. RECENT FINDINGS:A retrospective study suggests that it may be safe to advance the endoscope beyond the first circumferential burn to allow for a more complete assessment of extent of i...

journal_title：Current opinion in pediatrics

authors： Shub MD

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent developments in the assessment of changes in structure and function in the fetal heart with the focus on congenital heart disease malformations. RECENT FINDINGS:Use of the combination of the cardiovascular profile score, the biophysical profile score and additional physiol...

journal_title：Current opinion in pediatrics

authors： Acharya G,Archer N,Huhta JC

更新日期：2007-10-01 00:00:00