Leukocyte function and nonmalignant leukocyte disorders.

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe current concepts on inflammation, immunity and insulin resistance. Metabolic and immune systems are closely involved in inflammation and significantly contribute to the pathology seen in the pediatric intensive care unit. The ability of insulin to decrease hep...

journal_title：Current opinion in pediatrics

authors： Dhar A,Castillo L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Exposure to traffic-related air pollutants (TRAPs) has been implicated in asthma development, persistence, and exacerbation. This exposure is highly significant because increasingly large segments of the population worldwide reside in zones that have high levels of TRAP, including children, as schools...

journal_title：Current opinion in pediatrics

authors： Brandt EB,Myers JM,Ryan PH,Hershey GK

更新日期：2015-12-01 00:00:00

abstract：:Hypoxic-ischemic brain injury occurs frequently in infancy and childhood. Events such as perinatal asphyxia, near drowning, respiratory arrest, and near sudden infant death syndrome cause significant mortality and morbidity. Despite current critical care practices, the outcomes from such injuries may be life-long neur...

journal_title：Current opinion in pediatrics

authors： Biagas K

更新日期：1999-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This paper reviews recent publications about the physiology associated with adaptation to malnutrition and refeeding (including the refeeding syndrome) and clinical outcomes of refeeding paradigms. RECENT FINDINGS:A number of recent reviews and original publications have highlighted important differe...

journal_title：Current opinion in pediatrics

authors： Kohn MR,Madden S,Clarke SD

更新日期：2011-08-01 00:00:00

abstract：:Over the past two decades, pharmacokinetic data have clearly demonstrated that development can markedly influence the absorption, distribution, excretion, and metabolism of xenobiotics. With respect to many of the processes that govern drug metabolism, the underlying pharmacogenetic determinants that may control eithe...

journal_title：Current opinion in pediatrics

authors： Kearns GL

更新日期：1995-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to explore the effects of the opioid crisis on pediatric patients in the postoperative setting and provide recommendations for well-tolerated opioid prescribing practices. RECENT FINDINGS:Opioid overdoses have increased among all age groups, predominantly related to over...

journal_title：Current opinion in pediatrics

authors： Harbaugh CM,Gadepalli SK

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews three common abnormalities requiring surgical treatment in adults with congenital heart disease (CHD): Ebstein's anomaly, the failing Fontan, and pulmonary valve disease. RECENT FINDINGS:As of 2000, more adults than children are alive with CHD. Each year, more of these adults wit...

journal_title：Current opinion in pediatrics

authors： Dearani JA,Mavroudis C,Quintessenza J,Deal BJ,Backer CL,Fitzgerald P,Connolly HM,Jacobs JP

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The International Liaison Committee on Resuscitation (ILCOR) recommends initiating neonatal resuscitation with concentrations of oxygen between 21 and 100%. This wide range of oxygen concentrations recommended for resuscitation highlights the lack of evidence supporting either 21 or 100% O2. The purpo...

journal_title：Current opinion in pediatrics

authors： Ten VS,Matsiukevich D

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Altered epigenetics is central to oncogenesis in many pediatric cancers. Aberrant epigenetic states are induced by mutations in histones or epigenetic regulatory genes, aberrant expression of genes regulating chromatin complexes, altered DNA methylation patterns, or dysregulated expression of noncodin...

journal_title：Current opinion in pediatrics

authors： Panditharatna E,Filbin MG

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this Position Statement is to emphasize the importance of an affirmative approach to the health care of transgender individuals, as well as to improve the understanding of the rights of transgender youth. RECENT FINDINGS:Transgender youth have optimal outcomes when affirmed in their ge...

journal_title：Current opinion in pediatrics

authors： Lopez X,Marinkovic M,Eimicke T,Rosenthal SM,Olshan JS,Pediatric Endocrine Society Transgender Health Special Interest Group.

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Juvenile myasthenia gravis is a relatively rare autoimmune neuromuscular disorder. The pathophysiology of juvenile myasthenia gravis is similar to that of adult myasthenia gravis, though there remain important differences regarding presentation and therapeutic options. We review the pathophysiology, c...

journal_title：Current opinion in pediatrics

authors： Liew WK,Kang PB

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing numbers of children are now traveling to high-altitude destinations, and pediatricians often see these children prior to and immediately following their travels. Thus, pediatricians have the opportunity to provide guidance for the prevention of altitude illness and must treat high-altitude ...

journal_title：Current opinion in pediatrics

authors： Garlick V,O'Connor A,Shubkin CD

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Simulation has been widely adopted as a training and assessment tool in medical education. Conventional teaching methods may be inadequate to properly train healthcare providers for rare but potentially lethal events in pediatrics such as trauma and respiratory arrest. Recent studies suggest pediatric...

journal_title：Current opinion in pediatrics

authors： Weinberg ER,Auerbach MA,Shah NB

更新日期：2009-06-01 00:00:00

abstract：:Atopic dermatitis is the most common chronic skin disease of young children and is frequently associated with asthma and allergies. Th2-type cytokine secreting T cells expressing the cutaneous lymphocyte-associated antigen play a central role in the induction of local IgE responses and recruitment of eosinophils in th...

journal_title：Current opinion in pediatrics

authors： Boguniewicz M

更新日期：1997-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic rhinitis, conjunctivitis, and asthma impact quality of life and cost billions of dollars in lost wages, productivity, and medical expenditures. Allergen immunotherapy is the only therapy that alters the allergen immune response, resulting in fewer symptoms upon natural exposure. This review s...

journal_title：Current opinion in pediatrics

authors： Vadlamudi A,Shaker M

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize recent research regarding the diagnosis of allergic rashes and to suggest future directions for the promotion of accurate diagnosis and endotype specification. RECENT FINDINGS:Multiple cohort studies demonstrate that with appropriate clinical evaluation, dru...

journal_title：Current opinion in pediatrics

authors： Happel CS

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight studies that have contributed significantly to our current knowledge of inhaled glucocorticoids in childhood asthma. RECENT FINDINGS:In 2006, three important studies were published that investigated whether inhaled glucocorticoid therapy, if started soon after the onset of asthma symptom...

journal_title：Current opinion in pediatrics

authors： Spahn JD,Szefler SJ

更新日期：2007-06-01 00:00:00

abstract：:Stachybotrys is a toxin-producing fungus that grows indoors when both water and cellulose are available. Epidemiologic evidence has demonstrated an association between acute pulmonary hemorrhage in infants and exposure to Stachybotrys and other fungi in water-damaged home environments. In recent years, advances in und...

journal_title：Current opinion in pediatrics

authors： Etzel RA

更新日期：2003-02-01 00:00:00

abstract：:Necrotizing enterocolitis is an overwhelming gastrointestinal emergency that primarily afflicts premature infants born weighing less than 1500 g. Despite years of investigation, the etiology remains unclear, and accepted prevention and treatment strategies are lacking. Studies published over the last year have provide...

journal_title：Current opinion in pediatrics

authors： Caplan MS,Jilling T

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:An understanding of vaccine safety is important for all immunization providers, who have responsibilities to identify, report, and prevent adverse events. RECENT FINDINGS:New analytic methods can provide more rapid information on adverse events compared with traditional observational studies. Some ad...

journal_title：Current opinion in pediatrics

authors： Wharton M

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Slipped capital femoral epiphysis (SCFE) is the most common adolescent hip condition. Its importance lies in its high morbidity if not diagnosed and treated in its early stages, not only in childhood but also as a cause of osteoarthritis in adulthood. This article highlights key diagnostic tools and o...

journal_title：Current opinion in pediatrics

authors： Gholve PA,Cameron DB,Millis MB

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Abdominal wall defects comprising both gastroschisis and omphalocele remain a source of significant morbidity and mortality, despite the advances in neonatal and pediatric surgical care. Survival has improved over the past few decades, especially with parenteral nutrition and surgical repair. Yet, sti...

journal_title：Current opinion in pediatrics

authors： Islam S

更新日期：2008-06-01 00:00:00

abstract：:The development of the attachment behavioral system in infancy has been the focus of a wide range of research in the past 30 years. The clinical significance of disturbances in this area of development is currently a major focus for this research. Research on patterns of attachment in infancy has informed understandin...

journal_title：Current opinion in pediatrics

authors： Boris NW,Zeanah CH

更新日期：1998-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Neonatal erythroderma is a potentially life-threatening condition in neonates less than 1 month old. During the first month of life, erythroderma is generally a presentation of genodermatosis, primary immune deficiency, or, more exceptionally, severe psoriasis, metabolic disease or infection. Atopic e...

journal_title：Current opinion in pediatrics

authors： Fraitag S,Bodemer C

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent publications on the use of the Internet as it relates to pediatric primary care, including its application to the pediatrician, teen, pediatric patient, and patients' parents. A brief overview of early work is introduced. RECENT FINDINGS:The Internet has become a tool to...

journal_title：Current opinion in pediatrics

authors： Kind T

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The small bowel has been a technically difficult area to examine. Indirect modalities such as barium follow-through have the disadvantage of attendant radiation exposure. Capsule endoscopy, a novel wireless method of investigation of the small bowel, has acquired an important role in both adult and pa...

journal_title：Current opinion in pediatrics

authors： Sidhu R,McAlindon ME,Sanders DS,Thomson M

更新日期：2007-10-01 00:00:00

abstract：:Inhalants remain one of the most commonly abused substances by adolescents in the United States today. Recent epidemiologic studies have demonstrated a decrease in the prevalence of inhalant abuse, but overall rates remain high. Inhalants have the potential to result in serious organ system dysfunction or even sudden ...

journal_title：Current opinion in pediatrics

authors： Lorenc JD

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Neurodevelopmental-behavioural paediatrics (NBP) is a field of medical practice that has arisen in response to recent changes in child health epidemiology. This review considers how the profession of NBP is addressing clinical need, and discusses possibilities for future development of the field. REC...

journal_title：Current opinion in pediatrics

authors： McDowell M,Lesslie J

更新日期：2019-12-01 00:00:00

abstract：:In the 7 years since the cystic fibrosis (CF) gene has been cloned, many experimental trials of population screening for CF heterozygotes have been reported. Targeting young adults near reproductive age has shown that the method in which screening is offered is a major determinant of acceptance rates: personal invitat...

journal_title：Current opinion in pediatrics

authors： Brock DJ

更新日期：1996-12-01 00:00:00

abstract：PURPOSE OF REVIEW:A brief delay in clamping the umbilical cord after birth offers health benefits to the newborn, with no adverse effects to the mother or her infant. Yet, in most obstetric practice, the cord is clamped soon after birth. A summary of the current evidence on delayed cord clamping and some reasons for th...

journal_title：Current opinion in pediatrics

authors： Raju TN

更新日期：2013-04-01 00:00:00