Pediatric postoperative opioid prescribing and the opioid crisis.

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight the recent advances in epigenetic regulation and chromatin biology for a better understanding of gene regulation related to human disease. RECENT FINDINGS:Alterations to chromatin influence genomic function, including gene transcription. At its most simple l...

journal_title：Current opinion in pediatrics

authors： Iglesias-Platas I,Monk D

更新日期：2016-08-01 00:00:00

abstract：:Genetic causes account for 20% to 25% of human birth defects, but the largest proportion of birth defects have no definitive etiology and some of these malformations may be due to intrinsic, "nonpreventable" spontaneous errors of development. Environmental causes, which include maternal disease states, maternal infect...

journal_title：Current opinion in pediatrics

authors： Brent RL,Beckman DA,Landel CP

更新日期：1993-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Neurodevelopmental-behavioural paediatrics (NBP) is a field of medical practice that has arisen in response to recent changes in child health epidemiology. This review considers how the profession of NBP is addressing clinical need, and discusses possibilities for future development of the field. REC...

journal_title：Current opinion in pediatrics

authors： McDowell M,Lesslie J

更新日期：2019-12-01 00:00:00

abstract：:Developmental care is a framework that encompasses all care procedures as well as social and physical aspects in the newborn intensive care unit. Its goal is to support each individual infant to be as stable, well-organized, and competent as possible. The infant's physiologic and behavioral expression of current funct...

journal_title：Current opinion in pediatrics

authors： Als H

更新日期：1998-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective mutism is a disorder in which an individual fails to speak in certain social situations though speaks normally in other settings. Most commonly, this disorder initially manifests when children fail to speak in school. Selective mutism results in significant social and academic impairment in ...

journal_title：Current opinion in pediatrics

authors： Hua A,Major N

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent progress in our understanding of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders. RECENT FINDINGS:A number of Mendelian disorders of immune dysregulation and autoimmunity have been noted to result from defects in T regulatory cell,...

journal_title：Current opinion in pediatrics

authors： Verbsky JW,Chatila TA

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:SARS-CoV-2 is the novel human coronavirus responsible for the COVID19 pandemic. Accurate detection of infection with SARS-CoV-2 is an essential component of efforts to treat individual patients and to contain spread of the virus in the community. The purpose of this review is to describe current diagn...

journal_title：Current opinion in pediatrics

authors： Spearman P

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to review advances in both the pathogenesis and clinical management of biliary atresia. RECENT FINDINGS:Immunologic studies have further characterized roles of helper T-cells, B-cells, and natural killer cells in the immune dysregulation following viral replication within...

journal_title：Current opinion in pediatrics

authors： Zagory JA,Nguyen MV,Wang KS

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The clinical importance of overgrowth syndromes in the pediatric patient population has been increasingly recognized during the past decade, but clinical overlap among overgrowth syndromes often makes diagnostic categorization difficult. Advances in the molecular delineation of overgrowth syndromes in...

journal_title：Current opinion in pediatrics

authors： Cytrynbaum CS,Smith AC,Rubin T,Weksberg R

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This study reviews the history of neonatal drug development, recent legislative efforts designed to facilitate the study of therapeutic agents in neonates, and future steps necessary to advance drug development. RECENT FINDINGS:Although many federal regulations have been introduced over the past 15 y...

journal_title：Current opinion in pediatrics

authors： Smith AM,Davis JM

更新日期：2017-04-01 00:00:00

abstract：:Gastrointestinal issues are a major chronic problem in 80 to 90% of children with cerebral palsy and in children with neurodevelopmental disabilities who are at special risk of developing malnutrition because of uncoordinated swallowing, gastroesophageal reflux, and constipation. In addition to poor linear growth, the...

journal_title：Current opinion in pediatrics

authors： Chong SK

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Major advances in our understanding of the genetic basis of neuroblastoma, and the role somatic alterations play in driving tumor growth, have led to improvements in risk-stratified therapy and have provided the rationale for targeted therapies. In this review, we highlight current risk-based treatmen...

journal_title：Current opinion in pediatrics

authors： Bagatell R,Cohn SL

更新日期：2016-02-01 00:00:00

abstract：:The biology of human breast milk, and the policy of encouraging breastfeeding, continue to be the object of much scientific inquiry. The past year has seen several advances in these fields of nutrition, and this article reviews some of the most interesting and pertinent studies. Four general themes have been apparent ...

journal_title：Current opinion in pediatrics

authors： Kelleher DK,Duggan C

更新日期：1999-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Identifying pathogenic variation underlying pediatric developmental disease is critical for medical management, therapeutic development, and family planning. This review summarizes current genetic testing options along with their potential benefits and limitations. We also describe results from large-...

journal_title：Current opinion in pediatrics

authors： Neu MB,Bowling KM,Cooper GM

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Exposure to traffic-related air pollutants (TRAPs) has been implicated in asthma development, persistence, and exacerbation. This exposure is highly significant because increasingly large segments of the population worldwide reside in zones that have high levels of TRAP, including children, as schools...

journal_title：Current opinion in pediatrics

authors： Brandt EB,Myers JM,Ryan PH,Hershey GK

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonaccidental trauma and neglect continue to be major problems for children, families, and the providers who care for them. Whereas prevention is the key to ending child abuse and neglect, diagnosis and treatment continue to be the mainstays of practice. This article will briefly review the epidemiolo...

journal_title：Current opinion in pediatrics

authors： Tenney-Soeiro R,Wilson C

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Patient education is an essential component of asthma management. The current paradigm of asthma education has moved away from the 'information-transfer' programmes that characterized earlier approaches and that were shown to be largely ineffective, to approaches that promote self-management education...

journal_title：Current opinion in pediatrics

authors： Shah S,Roydhouse JK,Sawyer SM

更新日期：2008-12-01 00:00:00

abstract：:Nocturnal enuresis is a common problem occurring in 15% of children at 5 years of age. Although usually self-limiting, justification for early treatment is founded in the psychological impact on the child. The physician's role in treating enuresis is first to rule out structural causes for enuresis. After this has bee...

journal_title：Current opinion in pediatrics

authors： Gandhi KK

更新日期：1994-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to provide primary care physicians with updates on recent literature regarding clubfoot and answer questions asked by parents and caregivers of children with clubfoot. The topics discussed include prenatal counseling, relapse after Ponseti treatment, long-term outcomes following succe...

journal_title：Current opinion in pediatrics

authors： Yau A,Doyle SM

更新日期：2020-02-01 00:00:00

abstract：:Injury is our children's greatest health problem, and pediatricians will frequently see finger and hand injuries in the office and emergency room. Many of these will be fingertip crush injuries, which are quite common in toddlers and are often undertreated. Pediatric finger and wrist fractures and sprains generally do...

journal_title：Current opinion in pediatrics

authors： Innis PC

更新日期：1995-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This article evaluates the field of radiogenomics within recent developments in genomics and radiation biology. RECENT FINDINGS:Many pediatric cancer survivors have undergone treatment with radiation, putting them at risk for long-term side-effects associated with this therapy, especially cardiac dis...

journal_title：Current opinion in pediatrics

authors： Roberson JD 2nd,Burnett OL 3rd,Robin N

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the pathogenesis of pulmonary edema and describe recent discoveries related to the clearance of airspace fluid and potential new therapies for this life-threatening disorder. RECENT FINDINGS:It is clinically important to determine the mechanisms responsible for the clearance...

journal_title：Current opinion in pediatrics

authors： O'Brodovich H

更新日期：2005-06-01 00:00:00

abstract：:A 15-year-old girl was referred for a thyroid gland mass, which rapidly enlarged in the brief interval between initial evaluation and surgery. Fine needle aspiration of the mass suggested a diagnosis of papillary thyroid carcinoma. Upon pathological examination of this aggressive tumor, an "insular" pattern of tumor w...

journal_title：Current opinion in pediatrics

authors： Yusuf K,Reyes-Mugica M,Carpenter TO

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This update reviews the concepts underlying ethical issues in various contexts and countries, highlighting the evolution in the use of the core values underpinning the field and practice of bioethics as applied to healthcare. RECENT FINDINGS:It stresses the specific position of the adolescent as bein...

journal_title：Current opinion in pediatrics

authors： Michaud PA,Berg-Kelly K,Macfarlane A,Benaroyo L

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent literature regarding assessment, management and prevention of child maltreatment will be considered. Unexplained infant and child death will also be reviewed. RECENT FINDINGS:Controversies in the evaluation of unexpected infant death and inflicted traumatic brain injury are ongoing. Evidence c...

journal_title：Current opinion in pediatrics

authors： Newton AW,Vandeven AM

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Disorders of hemostasis such as hemophilia, von Willebrand disease (VWD), and other clotting protein deficiencies lead to significant morbidity in the pediatric population. Because of the limitations of current treatment options, novel therapies are being developed, many of which are reviewed here. R...

journal_title：Current opinion in pediatrics

authors： Branchford BR,Monahan PE,Di Paola J

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Femoroacetabular impingement (FAI) post slipped capital femoral epiphysis (SCFE) may lead to degenerative changes on the hip. We have reviewed the current procedures in the literature, aiming to correct the SCFE to prevent FAI and the ones that treat FAI post SCFE. RECENT FINDINGS:The trends of manag...

journal_title：Current opinion in pediatrics

authors： Soni JF,Valenza WR,Uliana CS

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:In fiscally challenging times, scientists must seek creative strategies and leverage existing resources to advance research. RECENT FINDINGS:This review describes programmes supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to promote resear...

journal_title：Current opinion in pediatrics

authors： Burns KM,Pearson GD,Kaltman JR

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Recognizing inflammatory bowel disease (IBD) is straightforward when alarm symptoms are present, such as bloody diarrhea and weight loss. When the presentation is subtle or atypical, physicians must determine which patients warrant evaluation for IBD. Appropriate use of noninvasive tests can help iden...

journal_title：Current opinion in pediatrics

authors： Wong A,Bass D

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review addresses the importance of the prospective cohort design in large, unselected populations starting early in life for understanding the origins of childhood health disorders. RECENT FINDINGS:Cohort studies originating in healthy populations have contributed to great advances in hea...

journal_title：Current opinion in pediatrics

authors： Paneth N,Monk C

更新日期：2018-04-01 00:00:00