Radiogenomics: towards a personalized radiation oncology.

abstract：:The use of extracorporeal techniques for the treatment of pediatric diseases has expanded dramatically in the past decade. During this time, experience with both plasmapheresis and renal replacement therapy has become commonplace in ICUs and nephrology programs throughout the world. The indications for these therapies...

journal_title：Current opinion in pediatrics

authors： Bunchman TE

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Developmental speech and language disorders are common, seen in one in 20 preschool children, in the absence of frank neurological deficits or intellectual impairment. They are a key reason parents seek help from paediatricians. Complex neurogenetic and environmental contributions underpin the disorde...

journal_title：Current opinion in pediatrics

authors： Morgan A,Bonthrone A,Liégeois FJ

更新日期：2016-12-01 00:00:00

abstract：:Preimplantation genetic diagnosis now represents an alternative reproductive option for parents at high risk of having offspring affected with certain genetic diseases. Progress in the past year has included increasing reliability in embryo sexing by both polymerase chain reaction and fluorescent in situ hybridization...

journal_title：Current opinion in pediatrics

authors： Black SH

更新日期：1994-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review describes recent advances and unique challenges in precision medicine for pediatric cancers and highlights clinical trials assessing the clinical impact of targeted therapy matched to molecular alterations identified by tumor profiling. RECENT FINDINGS:Multiple prospective clinical...

journal_title：Current opinion in pediatrics

authors： Forrest SJ,Geoerger B,Janeway KA

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this article is to present an overview of the state of breastfeeding in the United States and to examine recent evidence for strategies aimed at optimizing successful breastfeeding in the neonatal period. RECENT FINDINGS:Although rates of any and exclusive breastfeeding are rising, Ame...

journal_title：Current opinion in pediatrics

authors： Cramton R,Zain-Ul-Abideen M,Whalen B

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Nearing the end of the first decade of this new century, the challenges and changes in the field of outpatient pediatric cardiology continue to accelerate. RECENT FINDINGS:To help the general pediatrician and family practice physician become aware of several new care guidelines and practice trends as...

journal_title：Current opinion in pediatrics

authors： Lacina SJ

更新日期：2009-10-01 00:00:00

abstract：:Autoimmune Lymphoproliferative Syndrome (ALPS) is a recently recognized disease in which a genetic defect in programmed cell death, or apoptosis, leads to breakdown of lymphocyte homeostasis and normal immunologic tolerance. Some authors have referred to ALPS as Canale-Smith syndrome or lymphoproliferative syndrome wi...

journal_title：Current opinion in pediatrics

authors： Jackson CE,Puck JM

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Ras pathway mutations are one of the most common type of alterations in pediatric hematologic malignancies and are frequently associated with adverse outcomes. Despite ongoing efforts to use targeted treatments, there remain no Food and Drug Administration (FDA)-approved medications specifically for c...

journal_title：Current opinion in pediatrics

authors： Pikman Y,Stieglitz E

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe current concepts on inflammation, immunity and insulin resistance. Metabolic and immune systems are closely involved in inflammation and significantly contribute to the pathology seen in the pediatric intensive care unit. The ability of insulin to decrease hep...

journal_title：Current opinion in pediatrics

authors： Dhar A,Castillo L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Children with chronic kidney disease (CKD) have impaired growth that leads to short stature in adulthood. The problem persists even with successful transplantation and steroid withdrawal protocols. The aim of this review is to provide an overview of the pressing issues related to growth failure in chi...

journal_title：Current opinion in pediatrics

authors： Ingulli EG,Mak RH

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:According to recent Centers for Disease Control (CDC) data, the annual incidence of traumatic brain injury (TBI) in the United States is 1.6-3.2 million, of which the majority is classified as mild. Over half of these injuries occur in the pediatric population, and can often be attributed to a sports-...

journal_title：Current opinion in pediatrics

authors： Choe MC,Babikian T,DiFiori J,Hovda DA,Giza CC

更新日期：2012-12-01 00:00:00

abstract：:Bacterial meningitis is an important problem in childhood. Vaccines can prevent Haemophilus influenzae type b disease and are being developed for infections caused by meningococci and pneumococci. Lumbar puncture is an important part of the diagnostic workup although care is required with its use. Once meningitis is d...

journal_title：Current opinion in pediatrics

authors： Booy R,Kroll S

更新日期：1994-02-01 00:00:00

abstract：:Bone marrow transplantation has become well established in the treatment of malignant and nonmalignant disorders. Steady progress continues in improving survival after transplantation, but many problems remain to be solved. Relapsed disease is a major limitation, and new, more intensive preparative regimens are being ...

journal_title：Current opinion in pediatrics

authors： Robertson KA

更新日期：1993-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Acne vulgaris remains one of the most common conditions affecting adolescents. The pediatric practitioner is the first to evaluate adolescent acne, making familiarity with the condition and its management essential. This review covers some of the recent literature regarding acne to help practitioners ...

journal_title：Current opinion in pediatrics

authors： Tom WL,Barrio VR

更新日期：2008-08-01 00:00:00

abstract：:Slipped capital femoral epiphysis remains a diagnostic problem despite numerous papers written on the subject. The most important factor in the diagnosis of slipped capital femoral epiphysis is suspicion by the practitioner. The history, physical examination, and radiographic imaging are important in the confirmation ...

journal_title：Current opinion in pediatrics

authors： Reynolds RA

更新日期：1999-02-01 00:00:00

abstract：:Attention deficit hyperactivity disorder is one of the most common behavioral disorders of childhood and is frequently assessed and treated by pediatricians and other primary care physicians. The diagnosis of attention deficit hyperactivity disorder is based on the careful synthesis of clinical data derived from multi...

journal_title：Current opinion in pediatrics

authors： McGough JJ,McCracken JT

更新日期：2000-08-01 00:00:00

abstract：:Cerebral palsy is caused by a static lesion to the cerebral motor cortex that is acquired before, at, or within 5 years of birth. Multiple causes for the condition exist and include cerebral anoxia, cerebral hemorrhage, infection, and genetic syndromes. Cerebral palsy is commonly classified according to the type of mo...

journal_title：Current opinion in pediatrics

authors： Dabney KW,Lipton GE,Miller F

更新日期：1997-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes for the pediatrician the current understanding of normal cerebellar and brainstem development, and then discusses selected malformations to highlight advances in the area. The impact of prematurity on cerebellar growth and development is then examined. The important insights pro...

journal_title：Current opinion in pediatrics

authors： Limperopoulos C,du Plessis AJ

更新日期：2006-12-01 00:00:00

abstract：:Necrotizing enterocolitis is an overwhelming gastrointestinal emergency that primarily afflicts premature infants born weighing less than 1500 g. Despite years of investigation, the etiology remains unclear, and accepted prevention and treatment strategies are lacking. Studies published over the last year have provide...

journal_title：Current opinion in pediatrics

authors： Caplan MS,Jilling T

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Over 80% of children diagnosed with cancer are now cured. The burgeoning population of survivors of childhood cancer experiences high rates of morbidity and mortality due to 'late-effects' of treatment. These can be defined as any consequence of treatment that persists beyond or develops after the com...

journal_title：Current opinion in pediatrics

authors： Song A,Fish JD

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Infantile spasms, mental retardation, autism, and dystonia represent disabling diseases for which little etiologic information is available. Mutations in the Aristaless related homeobox gene (ARX) have been found in patients with these conditions. This discovery provides important genetic information ...

journal_title：Current opinion in pediatrics

authors： Sherr EH

更新日期：2003-12-01 00:00:00

abstract：:Superior mesenteric artery (SMA) syndrome describes vascular compression of the third portion of the duodenum and presents with nausea, postprandial vomiting, and epigastric abdominal pain. The syndrome is rare and may be missed if appropriate radiologic studies are not performed or the clinical presentation is atypic...

journal_title：Current opinion in pediatrics

authors： Kurbegov A,Grabb B,Bealer J

更新日期：2010-10-01 00:00:00

abstract：:The sustained improvements in pediatric cancer therapy are partially due to the large randomized and nonrandomized studies being conducted by multidisciplinary cooperative groups. Theoretic concepts of chemotherapy are better knowledge of the pharmacokinetics, pharmacodynamics, and drug resistance of current and new d...

journal_title：Current opinion in pediatrics

authors： Rogers P,Karabus C

更新日期：1993-02-01 00:00:00

abstract：:Fetal cardiac intervention is in a rapid state of progress now. Attempts are being made to prevent fetal hydrops due to congenital heart defects, to recruit hypoplastic ventricles, to create a two-ventricle circulation after birth, and to remodel the fetal pulmonary vascular bed whose outlet is obstructed. Open heart ...

journal_title：Current opinion in pediatrics

authors： Huhta J,Quintero RA,Suh E,Bader R

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Physical activity has been highlighted internationally as a beneficial intervention for weight control and the improvement of physical and mental health. This review highlights findings from recent literature to guide office-based promotion of physical activity for obesity treatment and prevention. R...

journal_title：Current opinion in pediatrics

authors： Floriani V,Kennedy C

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Neurodevelopmental-behavioural paediatrics (NBP) is a field of medical practice that has arisen in response to recent changes in child health epidemiology. This review considers how the profession of NBP is addressing clinical need, and discusses possibilities for future development of the field. REC...

journal_title：Current opinion in pediatrics

authors： McDowell M,Lesslie J

更新日期：2019-12-01 00:00:00

abstract：:A careful history and physical examination will help to differentiate between encopresis with or without constipation and fecal incontinence caused by anatomic or organic disease. Most children with encopresis with or without functional constipation require no or minimal laboratory workup. Successful treatment of enco...

journal_title：Current opinion in pediatrics

authors： Loening-Baucke V

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:In September 2019, the United States was at risk of losing measles elimination status due to several large-scale outbreaks resulting in more than 1200 confirmed cases across 31 states. This resurgence caps approximately 10 years of increasing incidence, marked by a highly publicized outbreak in 2015 a...

journal_title：Current opinion in pediatrics

authors： Feemster KA,Szipszky C

更新日期：2020-02-01 00:00:00

abstract：:Outcomes for infants with gastroschisis have paralleled advances made in neonatal intensive care and the use of parenteral nutrition. Mortality rates approaching 100% a half century ago are now closer to 2% to 8%. Further reduction in morbidity has been the focus of many studies during the past decade. Efforts have be...

journal_title：Current opinion in pediatrics

authors： Schlatter M

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will focus on therapeutic considerations and recent advances in treatment of caustic ingestion injuries. RECENT FINDINGS:A retrospective study suggests that it may be safe to advance the endoscope beyond the first circumferential burn to allow for a more complete assessment of extent of i...

journal_title：Current opinion in pediatrics

authors： Shub MD

更新日期：2015-10-01 00:00:00