Insular carcinoma of the thyroid in an adolescent: a case report and review of the literature.

abstract：:Complete deficiency of one of the early components (C1, C4, or C2) of the classical pathway of the complement cascade is one of the strongest genetic risk factors for systemic lupus erythematosus that has been recognized. The lupus that occurs in complement-deficient individuals typically presents in early childhood. ...

journal_title：Current opinion in pediatrics

authors： Sullivan KE

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Prenatal genetic screening and diagnostic testing can identify many disorders that will require specialized newborn care and follow-up. Pediatricians should be aware of recent advances in testing that may have implications for their patients and families. RECENT FINDINGS:Over the last half decade, th...

journal_title：Current opinion in pediatrics

authors： Cunniff C,Hudgins L

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, recent advances in the epidemiology, genetics, clinical associations and management of idiopathic hypercalciuria will be discussed. RECENT FINDINGS:A significant genetic contribution exists in the pathophysiology of hypercalciuria. Although several candidate genes and genetic alterati...

journal_title：Current opinion in pediatrics

authors： Srivastava T,Schwaderer A

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Sepsis is the leading cause of pediatric death worldwide. In the United States alone, there are 72 000 children hospitalized for sepsis annually with a reported mortality rate of 25% and an economic cost estimated to be $4.8 billion. However, it is only recently that the definition and management of p...

journal_title：Current opinion in pediatrics

authors： Mathias B,Mira JC,Larson SD

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize the recent literature investigating nonoperative management of uncomplicated and complicated appendicitis and highlight recent data establishing its safety and efficacy. RECENT FINDINGS:Recent studies and clinical trials have demonstrated the efficacy of nonoper...

journal_title：Current opinion in pediatrics

authors： López JJ,Deans KJ,Minneci PC

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Neurodevelopmental-behavioural paediatrics (NBP) is a field of medical practice that has arisen in response to recent changes in child health epidemiology. This review considers how the profession of NBP is addressing clinical need, and discusses possibilities for future development of the field. REC...

journal_title：Current opinion in pediatrics

authors： McDowell M,Lesslie J

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The clinical importance of overgrowth syndromes in the pediatric patient population has been increasingly recognized during the past decade, but clinical overlap among overgrowth syndromes often makes diagnostic categorization difficult. Advances in the molecular delineation of overgrowth syndromes in...

journal_title：Current opinion in pediatrics

authors： Cytrynbaum CS,Smith AC,Rubin T,Weksberg R

更新日期：2005-12-01 00:00:00

abstract：:Fetal cardiac intervention is in a rapid state of progress now. Attempts are being made to prevent fetal hydrops due to congenital heart defects, to recruit hypoplastic ventricles, to create a two-ventricle circulation after birth, and to remodel the fetal pulmonary vascular bed whose outlet is obstructed. Open heart ...

journal_title：Current opinion in pediatrics

authors： Huhta J,Quintero RA,Suh E,Bader R

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Radiation exposure from computed tomography is associated with a small but significant increase in risk for fatal cancer over a child's lifetime. This review aims to heighten awareness and spearhead efforts to reduce unnecessary computed tomography scans in children. RECENT FINDINGS:The use of pediat...

journal_title：Current opinion in pediatrics

authors： Shah NB,Platt SL

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has become increasingly important as a cause of skin and soft tissue infections (SSTIs), particularly abscesses, in patients seen in the emergency department setting. The antibiotic sensitivity profile of Staphylococcus aureus ...

journal_title：Current opinion in pediatrics

authors： Odell CA

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:SARS-CoV-2 is the novel human coronavirus responsible for the COVID19 pandemic. Accurate detection of infection with SARS-CoV-2 is an essential component of efforts to treat individual patients and to contain spread of the virus in the community. The purpose of this review is to describe current diagn...

journal_title：Current opinion in pediatrics

authors： Spearman P

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Disorders of hemostasis such as hemophilia, von Willebrand disease (VWD), and other clotting protein deficiencies lead to significant morbidity in the pediatric population. Because of the limitations of current treatment options, novel therapies are being developed, many of which are reviewed here. R...

journal_title：Current opinion in pediatrics

authors： Branchford BR,Monahan PE,Di Paola J

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:We present data from recently conducted research regarding the diagnosis of blunt cervical spine injury (CSI) in children. RECENT FINDINGS:Research in the prehospital setting to evaluate the need for cervical spine immobilization in children, regardless of clinical findings or mechanism of injury, su...

journal_title：Current opinion in pediatrics

authors： Tilt L,Babineau J,Fenster D,Ahmad F,Roskind CG

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Considerable attention has recently been focused on the pathogenesis, diagnosis and treatment of osteogenesis imperfecta. Two new genes have been defined in patients with recessive severe or lethal osteogenesis imperfecta types. Diagnostic concerns involve testing procedures, either skin biopsies or D...

journal_title：Current opinion in pediatrics

authors： Shapiro JR,Sponsellor PD

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review describes recent advances and unique challenges in precision medicine for pediatric cancers and highlights clinical trials assessing the clinical impact of targeted therapy matched to molecular alterations identified by tumor profiling. RECENT FINDINGS:Multiple prospective clinical...

journal_title：Current opinion in pediatrics

authors： Forrest SJ,Geoerger B,Janeway KA

更新日期：2018-02-01 00:00:00

abstract：:Hypoxic-ischemic brain injury occurs frequently in infancy and childhood. Events such as perinatal asphyxia, near drowning, respiratory arrest, and near sudden infant death syndrome cause significant mortality and morbidity. Despite current critical care practices, the outcomes from such injuries may be life-long neur...

journal_title：Current opinion in pediatrics

authors： Biagas K

更新日期：1999-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This update reviews the concepts underlying ethical issues in various contexts and countries, highlighting the evolution in the use of the core values underpinning the field and practice of bioethics as applied to healthcare. RECENT FINDINGS:It stresses the specific position of the adolescent as bein...

journal_title：Current opinion in pediatrics

authors： Michaud PA,Berg-Kelly K,Macfarlane A,Benaroyo L

更新日期：2010-08-01 00:00:00

abstract：:Dietary long-chain polyunsaturated fatty acids have demonstrable beneficial effects on early development. The effects on neural development are of particular interest. Human milk is the best and only time-proven source of fat and essential fatty acids in the infant diet. Technologic procedures based on chemical and ph...

journal_title：Current opinion in pediatrics

authors： Uauy R,Mena P

更新日期：1999-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Owing to its aggressive clinical course and associated immunologic abnormalities, pediatric inflammatory bowel disease (IBD) is increasingly managed with immunomodulators and biologic agents. Clinical experience with therapy targeted against tumor necrosis factor-alpha has raised important questions a...

journal_title：Current opinion in pediatrics

authors： Rosh JR

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The literature was reviewed to describe the role of gait analysis in the orthopaedic management of ambulatory children with cerebral palsy and examine the current best evidence to support these roles. RECENT FINDINGS:Gait laboratory analysis is superior to visual or observational analysis of gait bec...

journal_title：Current opinion in pediatrics

authors： Narayanan UG

更新日期：2007-02-01 00:00:00

abstract：:Inhaled corticosteroids (ICS) have become the mainstay of therapy in chronic childhood asthma. Despite the long history and the documented efficacy of these drugs in controlling asthma, concerns still abound regarding the safety of these drugs in children, most specifically related to the potential for adrenal suppres...

journal_title：Current opinion in pediatrics

authors： Bazzy-Asaad A

更新日期：2001-12-01 00:00:00

abstract：:Cutaneous reactions to penicillin-type antibiotics are usually caused by IgE-mediated reactions directed toward the beta-lactam ring (in penicillin, ampicillin-amoxicillin, and cephalosporins). These allergic reactions may be reliably diagnosed (96% to 99% of the time) with a battery of skin tests derived from penicil...

journal_title：Current opinion in pediatrics

authors： Anderson JA

更新日期：1994-12-01 00:00:00

abstract：:Endocrine excesses or deficiencies frequently result in alterations of height as compared with age-matched children. Less clinically obvious are significant alterations in bone metabolism leading to osteoporosis, which can affect the child and may affect the patient as an adult. Slipped capital femoral epiphysis appea...

journal_title：Current opinion in pediatrics

authors： Mann DC

更新日期：1996-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite advances in medical care, preterm birth and its associated racial/ethnic disparities remain major public health issues. Environmental exposures may contribute to racial disparities in preterm birth. RECENT FINDINGS:Recent work in Iran demonstrated lead levels less than 10 μg/dl to be associat...

journal_title：Current opinion in pediatrics

authors： Burris HH,Collins JW Jr,Wright RO

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review addresses the importance of the prospective cohort design in large, unselected populations starting early in life for understanding the origins of childhood health disorders. RECENT FINDINGS:Cohort studies originating in healthy populations have contributed to great advances in hea...

journal_title：Current opinion in pediatrics

authors： Paneth N,Monk C

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The HIV/AIDS epidemic is one of the most widespread public health problems today. Teens with mental health concerns are particularly vulnerable to infection because they engage in higher rates of risky behaviors than their peers. Families are vital influences in protecting teens from HIV exposure, but...

journal_title：Current opinion in pediatrics

authors： Jordan K,Donenberg G

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The International Liaison Committee on Resuscitation (ILCOR) recommends initiating neonatal resuscitation with concentrations of oxygen between 21 and 100%. This wide range of oxygen concentrations recommended for resuscitation highlights the lack of evidence supporting either 21 or 100% O2. The purpo...

journal_title：Current opinion in pediatrics

authors： Ten VS,Matsiukevich D

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Major advances in our understanding of the genetic basis of neuroblastoma, and the role somatic alterations play in driving tumor growth, have led to improvements in risk-stratified therapy and have provided the rationale for targeted therapies. In this review, we highlight current risk-based treatmen...

journal_title：Current opinion in pediatrics

authors： Bagatell R,Cohn SL

更新日期：2016-02-01 00:00:00

abstract：:In the 7 years since the cystic fibrosis (CF) gene has been cloned, many experimental trials of population screening for CF heterozygotes have been reported. Targeting young adults near reproductive age has shown that the method in which screening is offered is a major determinant of acceptance rates: personal invitat...

journal_title：Current opinion in pediatrics

authors： Brock DJ

更新日期：1996-12-01 00:00:00

abstract：:The biology of human breast milk, and the policy of encouraging breastfeeding, continue to be the object of much scientific inquiry. The past year has seen several advances in these fields of nutrition, and this article reviews some of the most interesting and pertinent studies. Four general themes have been apparent ...

journal_title：Current opinion in pediatrics

authors： Kelleher DK,Duggan C

更新日期：1999-06-01 00:00:00