Surgical advances in the treatment of adults with congenital heart disease.

abstract：PURPOSE OF REVIEW:The number of pediatric cancer survivors is growing rapidly as treatments become more effective. However, many current regimens cause gonadotoxicity and permanent infertility, significantly impacting quality of life. The purpose of this review is to update pediatric oncologists on risk factors for can...

journal_title：Current opinion in pediatrics

authors： Ginsberg JP

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Identifying pathogenic variation underlying pediatric developmental disease is critical for medical management, therapeutic development, and family planning. This review summarizes current genetic testing options along with their potential benefits and limitations. We also describe results from large-...

journal_title：Current opinion in pediatrics

authors： Neu MB,Bowling KM,Cooper GM

更新日期：2019-12-01 00:00:00

abstract：:Miniaturization of echocardiographic transducers, improved crystal technology, and enhanced digital processing of ultrasound signals have resulted in newer, more sophisticated equipment and imaging techniques. These technologic advances include transesophageal echocardiography, stress echocardiography (both pharmacolo...

journal_title：Current opinion in pediatrics

authors： Marx GR

更新日期：1995-10-01 00:00:00

abstract：:The sustained improvements in pediatric cancer therapy are partially due to the large randomized and nonrandomized studies being conducted by multidisciplinary cooperative groups. Theoretic concepts of chemotherapy are better knowledge of the pharmacokinetics, pharmacodynamics, and drug resistance of current and new d...

journal_title：Current opinion in pediatrics

authors： Rogers P,Karabus C

更新日期：1993-02-01 00:00:00

abstract：:A number of growth factors have been identified that participate in lung growth and repair. The early stages of the repair cascade are important in preventing the later development of fibrosis. Both transforming growth factor-beta and basic fibroblast growth factor can have beneficial effects when given early in some ...

journal_title：Current opinion in pediatrics

authors： Perkett EA

更新日期：1995-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The small bowel has been a technically difficult area to examine. Indirect modalities such as barium follow-through have the disadvantage of attendant radiation exposure. Capsule endoscopy, a novel wireless method of investigation of the small bowel, has acquired an important role in both adult and pa...

journal_title：Current opinion in pediatrics

authors： Sidhu R,McAlindon ME,Sanders DS,Thomson M

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Nearing the end of the first decade of this new century, the challenges and changes in the field of outpatient pediatric cardiology continue to accelerate. RECENT FINDINGS:To help the general pediatrician and family practice physician become aware of several new care guidelines and practice trends as...

journal_title：Current opinion in pediatrics

authors： Lacina SJ

更新日期：2009-10-01 00:00:00

abstract：:The major advance in knowledge about rotavirus infection and prevention has been in vaccine development. Several large studies of tetravalent rhesis rotavirus vaccine have had encouraging results, and a first-generation vaccine is likely to be licensed by the 25th anniversary of the discovery of rotavirus (in 1973). E...

journal_title：Current opinion in pediatrics

authors： Barnes GL,Bishop RF

更新日期：1997-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Recently, recommendations from the American Heart Association regarding treatment of streptococcal tonsillo-pharyngitis were revised. This review provides the background for changes that were made in comparison with the group's 1995 recommendations. Recent papers on other issues relating to group A St...

journal_title：Current opinion in pediatrics

authors： Baltimore RS

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Altered epigenetics is central to oncogenesis in many pediatric cancers. Aberrant epigenetic states are induced by mutations in histones or epigenetic regulatory genes, aberrant expression of genes regulating chromatin complexes, altered DNA methylation patterns, or dysregulated expression of noncodin...

journal_title：Current opinion in pediatrics

authors： Panditharatna E,Filbin MG

更新日期：2020-02-01 00:00:00

abstract：:Dyslipidemia increases the risk of cardiovascular events among individuals with renal disease, and there is a growing body of evidence that it hastens the progression of renal disease itself. Children with nephrotic syndrome or renal transplants have easily recognized hyperlipidemia. Among those with chronic renal ins...

journal_title：Current opinion in pediatrics

authors： Saland JM,Ginsberg H,Fisher EA

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Developmental speech and language disorders are common, seen in one in 20 preschool children, in the absence of frank neurological deficits or intellectual impairment. They are a key reason parents seek help from paediatricians. Complex neurogenetic and environmental contributions underpin the disorde...

journal_title：Current opinion in pediatrics

authors： Morgan A,Bonthrone A,Liégeois FJ

更新日期：2016-12-01 00:00:00

abstract：:Over the past two decades, pharmacokinetic data have clearly demonstrated that development can markedly influence the absorption, distribution, excretion, and metabolism of xenobiotics. With respect to many of the processes that govern drug metabolism, the underlying pharmacogenetic determinants that may control eithe...

journal_title：Current opinion in pediatrics

authors： Kearns GL

更新日期：1995-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The present coronavirus disease 2019 (COVID-19) pandemic has created additional challenges with an increased number of presumed healthy, full-term newborns being discharged at 24 h after delivery. Short lengths of stay raise the possibility of mother-infant dyads being less ready for discharge, define...

journal_title：Current opinion in pediatrics

authors： Harriel KL,Nolt D,Moore S,Kressly S,Bernstein HH

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a current review of recent publications with regards to intracranial hypertension. RECENT FINDINGS:Attempts were made to provide pediatric data; however, the recent completion of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) has provided a wealth of data with regards to ...

journal_title：Current opinion in pediatrics

authors： Jordan CO,Aylward SC

更新日期：2018-12-01 00:00:00

abstract：:Gastrointestinal issues are a major chronic problem in 80 to 90% of children with cerebral palsy and in children with neurodevelopmental disabilities who are at special risk of developing malnutrition because of uncoordinated swallowing, gastroesophageal reflux, and constipation. In addition to poor linear growth, the...

journal_title：Current opinion in pediatrics

authors： Chong SK

更新日期：2001-10-01 00:00:00

abstract：:Endocrine excesses or deficiencies frequently result in alterations of height as compared with age-matched children. Less clinically obvious are significant alterations in bone metabolism leading to osteoporosis, which can affect the child and may affect the patient as an adult. Slipped capital femoral epiphysis appea...

journal_title：Current opinion in pediatrics

authors： Mann DC

更新日期：1996-02-01 00:00:00

abstract：:Complete deficiency of one of the early components (C1, C4, or C2) of the classical pathway of the complement cascade is one of the strongest genetic risk factors for systemic lupus erythematosus that has been recognized. The lupus that occurs in complement-deficient individuals typically presents in early childhood. ...

journal_title：Current opinion in pediatrics

authors： Sullivan KE

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Inherited disorders of calcium and phosphate homeostasis have variable presentation and can cause significant morbidity. An understanding of the mode of inheritance and pathophysiology of these conditions will help in the diagnosis and early institution of therapy. RECENT FINDINGS:Identification of g...

journal_title：Current opinion in pediatrics

authors： Gattineni J

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:We present data from recently conducted research on the diagnosis and management of skin and soft tissue infections (SSTIs) in children. RECENT FINDINGS:Current research in the area of SSTIs (cellulitis and abscess) has focused on the use of ultrasound, risk factors associated with bacteremia, antibi...

journal_title：Current opinion in pediatrics

authors： Fenster DB,Renny MH,Ng C,Roskind CG

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Urinary tract infections are the most common serious bacterial infections in infants and young children. This review focuses on new additions to the literature for the period August 22, 2002, to August 21, 2003. RECENT FINDINGS:There is still considerable interest in determining which test is best to...

journal_title：Current opinion in pediatrics

authors： Wald E

更新日期：2004-02-01 00:00:00

abstract：:Preimplantation genetic diagnosis now represents an alternative reproductive option for parents at high risk of having offspring affected with certain genetic diseases. Progress in the past year has included increasing reliability in embryo sexing by both polymerase chain reaction and fluorescent in situ hybridization...

journal_title：Current opinion in pediatrics

authors： Black SH

更新日期：1994-12-01 00:00:00

abstract：:Attention deficit hyperactivity disorder is one of the most common behavioral disorders of childhood and is frequently assessed and treated by pediatricians and other primary care physicians. The diagnosis of attention deficit hyperactivity disorder is based on the careful synthesis of clinical data derived from multi...

journal_title：Current opinion in pediatrics

authors： McGough JJ,McCracken JT

更新日期：2000-08-01 00:00:00

abstract：:The insulin-like growht factors (IGFs) are potent mitogenic agents that have been recognized for three decades. Recently, however, the complex milieu in which they operate has begun to be unraveled. Endocrine and autocrine patterns of IGF secretion have been identified and specific receptors that bind IGFs and mediate...

journal_title：Current opinion in pediatrics

authors： Cohen P,Rosenfeld RG

更新日期：1994-08-01 00:00:00

abstract：:Smoking prevention during childhood and adolescence is critical to the successful reduction of tobacco-related morbidity and mortality in the United States. The research literature is replete with surveys describing youth smoking acquisition and related factors. In addition to its direct harm, tobacco use may be a gat...

journal_title：Current opinion in pediatrics

authors： Sockrider MM

更新日期：1997-06-01 00:00:00

abstract：:Treatment of patients with anorexia nervosa is a topic that continues to spark debate. Two particular areas of controversy include the role of exercise and the use of selective serotonergic reuptake inhibitors (SSRI). Few randomized controlled trials have addressed these two issues. The psychological impact of exercis...

journal_title：Current opinion in pediatrics

authors： Rosenblum J,Forman SF

更新日期：2003-06-01 00:00:00

abstract：:Lemierre's disease, also known as 'postanginal sepsis', 'necrobacillosis', or 'internal jugular vein thrombosis', is a rare but serious emerging infection. Although Lemierre's disease remains rare, the number of reported cases has risen in recent years as more judicious antimicrobial prescribing practices for viral up...

journal_title：Current opinion in pediatrics

authors： Sharma D,Rouphael N

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Acne vulgaris remains one of the most common conditions affecting adolescents. The pediatric practitioner is the first to evaluate adolescent acne, making familiarity with the condition and its management essential. This review covers some of the recent literature regarding acne to help practitioners ...

journal_title：Current opinion in pediatrics

authors： Tom WL,Barrio VR

更新日期：2008-08-01 00:00:00

abstract：:Prevention of injuries to child passengers is a significant public health priority, as motor vehicle-related injuries remain a leading cause of death for children. Improvements in child restraint use have contributed to significant declines in child occupant mortality rates over the past 20 years. However, although ov...

journal_title：Current opinion in pediatrics

authors： Durbin DR

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Joint hypermobility is a common, although largely ignored physical sign. Joint hypermobility is often asymptomatic but may be a feature of an underlying genetic disorder with systemic manifestations. The present article presents a comprehensive approach to considering joint hypermobility and clinicall...

journal_title：Current opinion in pediatrics

authors： Castori M,Hakim A

更新日期：2017-12-01 00:00:00