Preventing motor vehicle injuries.

abstract：:Large and unusually large von Willebrand factor (vWf) multimers may be responsible for systemic platelet aggregation in thrombotic thrombocytopenic purpura (TTP). This possibility is supported by studies that show deficient vWf-cleaving metalloproteinase and increased platelet-vWf binding during TTP episodes. In acute...

journal_title：Current opinion in pediatrics

authors： Baker KR,Moake JL

更新日期：2000-02-01 00:00:00

abstract：:Attention-deficit hyperactivity disorder has been redefined in the classifications in the International Classification of Disease, 10th revision and Diagnostic and Statistical Manual of Mental Disorders, fourth edition. The definitions are more concordant than their predecessors and reemphasize the distinction between...

journal_title：Current opinion in pediatrics

authors： Baxter PS

更新日期：1995-08-01 00:00:00

abstract：:Advances related to thyrotropin during 1999 included better understanding of the genetic basis of pituitary development and genetic advances in identifying clinical entities and their mechanisms and enabling new therapies. Initial clinical use of recombinant thyrotropin in evaluation of thyroid cancer recurrence was d...

journal_title：Current opinion in pediatrics

authors： Rose SR

更新日期：2000-08-01 00:00:00

abstract：:Guidelines are an increasingly prominent part of the practice of pediatrics. Aiming from studies of variability in care, they are widely used as a mechanism to assess and improve quality. Rigorous methods of guideline development differentiate current guidelines from past consensus efforts. The American Academy of Ped...

journal_title：Current opinion in pediatrics

authors： Homer CJ,Grossman RG,Rodman J

更新日期：1996-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Neonatal erythroderma is a potentially life-threatening condition in neonates less than 1 month old. During the first month of life, erythroderma is generally a presentation of genodermatosis, primary immune deficiency, or, more exceptionally, severe psoriasis, metabolic disease or infection. Atopic e...

journal_title：Current opinion in pediatrics

authors： Fraitag S,Bodemer C

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Altered epigenetics is central to oncogenesis in many pediatric cancers. Aberrant epigenetic states are induced by mutations in histones or epigenetic regulatory genes, aberrant expression of genes regulating chromatin complexes, altered DNA methylation patterns, or dysregulated expression of noncodin...

journal_title：Current opinion in pediatrics

authors： Panditharatna E,Filbin MG

更新日期：2020-02-01 00:00:00

abstract：:Advances in pediatric anesthesia can contribute to improved care of children in other environments. As an example, drugs and dosages established in preoperative sedation of children provide a base for their application in sedation and pain relief of children undergoing painful procedures in the emergency unit, oncolog...

journal_title：Current opinion in pediatrics

authors： Broennle AM,Cohen DE

更新日期：1993-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review outlines the current approaches to prenatal imaging, differential diagnosis, antenatal natural history, and the available treatment options for the most commonly prenatally diagnosed malignant tumors. RECENT FINDINGS:In-utero diagnosis of fetal tumors, although still a rare event, has bec...

journal_title：Current opinion in pediatrics

authors： Bruny J,Crombleholme TM

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews three common abnormalities requiring surgical treatment in adults with congenital heart disease (CHD): Ebstein's anomaly, the failing Fontan, and pulmonary valve disease. RECENT FINDINGS:As of 2000, more adults than children are alive with CHD. Each year, more of these adults wit...

journal_title：Current opinion in pediatrics

authors： Dearani JA,Mavroudis C,Quintessenza J,Deal BJ,Backer CL,Fitzgerald P,Connolly HM,Jacobs JP

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been an explosion in knowledge about celiac disease (CD) in the last decade based on the availability of serologic screening tests and the elucidation of some of the important disease susceptibility genes. What has been discovered is that CD is among the most common inherited diseases with a...

journal_title：Current opinion in pediatrics

authors： Treem WR

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Continuous glucose monitoring (CGM) is increasingly used in the management of diabetes in children and adults, but there are few data regarding its use in neonates. The purpose of this article is to discuss the potential benefits and limitations of CGM in neonates. RECENT FINDINGS:Smaller electrodes ...

journal_title：Current opinion in pediatrics

authors： Shah R,McKinlay CJD,Harding JE

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Lyme disease, caused by Borrelia burgdorferi, is the most common vector-borne illness in the United States. The pathogenesis, ecology, and epidemiology of Lyme disease have been well described, and antimicrobial treatment is very effective. There has been controversy about whether infection can persis...

journal_title：Current opinion in pediatrics

authors： Oliveira CR,Shapiro ED

更新日期：2015-02-01 00:00:00

abstract：:Three main factors are needed for an infant to develop allergy: allergen exposure, a genetic predisposition, and contributory factors. Recent literature suggests that the incidence of in utero sensitization might have been underestimated up to now. A number of papers provide evidence that atopic dermatitis should be r...

journal_title：Current opinion in pediatrics

authors： Vandenplas Y

更新日期：1993-10-01 00:00:00

abstract：:The Back to Sleep Campaigns remain the greatest influence on the reduction of sudden infant death syndrome. Blatt and Meguid review updates on the effectiveness of these campaigns in reducing sudden infant death syndrome. They also review studies on why parents do not follow this proven advice. The contribution of the...

journal_title：Current opinion in pediatrics

authors： Blatt SD,Meguid V,Church CC

更新日期：2000-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Atypical skull shapes occur in as many as 20% of infants. The purpose of this review is to discuss the clinical approach to the evaluation of a child with an abnormal head shape. Readers will learn how to identify the head shapes caused by environmental deformation and craniosynostosis. We also review...

journal_title：Current opinion in pediatrics

authors： Cunningham ML,Heike CL

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The interstitial lung diseases are a heterogeneous group of rare disorders of largely unknown etiology. The occurrence of familial cases of pediatric interstitial lung diseases with the onset of symptoms developing early in infancy has suggested a genetic basis for some forms of interstitial lung dise...

journal_title：Current opinion in pediatrics

authors： Nogee LM

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease is a common condition that may progress to end stage liver disease. It is closely associated with obesity and insulin resistance, two conditions whose prevalence is increasing dramatically in children. This could potentially make nonalcoholic fatty liver disease the mo...

journal_title：Current opinion in pediatrics

authors： Wieckowska A,Feldstein AE

更新日期：2005-10-01 00:00:00

abstract：:Smoking prevention during childhood and adolescence is critical to the successful reduction of tobacco-related morbidity and mortality in the United States. The research literature is replete with surveys describing youth smoking acquisition and related factors. In addition to its direct harm, tobacco use may be a gat...

journal_title：Current opinion in pediatrics

authors： Sockrider MM

更新日期：1997-06-01 00:00:00

abstract：:The sustained improvements in pediatric cancer therapy are partially due to the large randomized and nonrandomized studies being conducted by multidisciplinary cooperative groups. Theoretic concepts of chemotherapy are better knowledge of the pharmacokinetics, pharmacodynamics, and drug resistance of current and new d...

journal_title：Current opinion in pediatrics

authors： Rogers P,Karabus C

更新日期：1993-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to present an overview of sport-related concussion in the young athlete and review recent publications of clinical and scientific importance. RECENT FINDINGS:Recent findings show that young athletes are more susceptible to concussions than older athletes and more likely ...

journal_title：Current opinion in pediatrics

authors： Buzzini SR,Guskiewicz KM

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To illustrate potential risks and benefits of disease screening for newborns using the example of Duchenne muscular dystrophy. RECENT FINDINGS:There is a wide range in the reported positive predictive value for screening male newborns for Duchenne muscular dystrophy by the creatine kinase level on dr...

journal_title：Current opinion in pediatrics

authors： Kemper AR,Wake MA

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In many United States households, there are many substances used to control the exposure of our children to mosquitoes, mice and rats. This review provides information on common mosquito repellents and rodenticides used in households and discusses their toxicity, in order to help pediatricians better ...

journal_title：Current opinion in pediatrics

authors： Kendrick DB

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Spondylolysis is a common cause for back pain in the adolescent athlete. Increased awareness of the presentation of this subset of patients can aid in optimal outcomes. This paper aims to review the typical presentation of spondylolysis in the adolescent with specific focus on the adolescent athlete. ...

journal_title：Current opinion in pediatrics

authors： Kim HJ,Green DW

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Gynecomastia is a common finding in adolescent men. The primary care provider should feel equipped to thoroughly evaluate this condition and to differentiate physiologic from pathologic breast enlargement. The present review focuses on the epidemiology, pathogenesis, evaluation, and treatment of gynec...

journal_title：Current opinion in pediatrics

authors： Nordt CA,DiVasta AD

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous disorder involving benign growths in multiple organ systems of affected patients. Variable phenotypes from mild to severe have been reported for related as well as unrelated patients affected by TSC. The two causative genes, TSC1...

journal_title：Current opinion in pediatrics

authors： Au KS,Ward CH,Northrup H

更新日期：2008-12-01 00:00:00

abstract：:Pediatric cardiac intensive care has emerged as a distinct clinical entity to meet the unique needs of pediatric patients with congenital and acquired heart disease. This new subspecialty demands expertise and experience in the pediatric subspecialties of cardiology, intensive care, cardiac surgery, cardiac anesthesia...

journal_title：Current opinion in pediatrics

authors： Chang AC

更新日期：2000-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To emphasize an exploration of mechanisms of kidney stone disease based on a molecular understanding of excess urinary excretions of calcium, oxalate, cystine, and uric acid. RECENT FINDINGS:Hypercalciuria is discussed relative to mutations in the renal chloride genes CLCN5 and CLCNKB, WNK kinases, A...

journal_title：Current opinion in pediatrics

authors： Langman CB

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Anemia and thrombocytopenia are the most common hematological problems in neonates. Red blood cell (RBC) and platelet transfusions are the mainstays of therapy, but data to guide neonatal transfusion practices have been sparse. Recombinant hematopoietic growth factors represent another therapeutic alt...

journal_title：Current opinion in pediatrics

authors： Sallmon H,Sola-Visner M

更新日期：2012-02-01 00:00:00

abstract：:Allergen avoidance should be considered as a first line of defense for all types of allergic disease. For some allergens, such as the common pollens, significant avoidance may be difficult or even impossible to accomplish without major alterations in lifestyle. For others, however, particularly the common indoor aller...

journal_title：Current opinion in pediatrics

authors： Wood RA

更新日期：1993-12-01 00:00:00

abstract：:Cutaneous reactions to penicillin-type antibiotics are usually caused by IgE-mediated reactions directed toward the beta-lactam ring (in penicillin, ampicillin-amoxicillin, and cephalosporins). These allergic reactions may be reliably diagnosed (96% to 99% of the time) with a battery of skin tests derived from penicil...

journal_title：Current opinion in pediatrics

authors： Anderson JA

更新日期：1994-12-01 00:00:00