Rotavirus vaccines: an update.

Abstract:

PURPOSE OF REVIEW:Rotavirus infection is the most common cause of severe diarrhea disease in infants and young children worldwide and has a major global impact on childhood morbidity and mortality. Vaccination is the only control measure likely to have a significant impact on the incidence of severe dehydrating rotavirus disease. RECENT FINDINGS:Rotavirus disease prevention efforts suffered a great setback in 1999 with the withdrawal of the RRV-TV vaccine less than a year after its introduction. Several new rotavirus vaccine candidates have now been developed and are undergoing clinical trials. SUMMARY:New safe and effective rotavirus vaccines offer the best hope of reducing the toll of acute rotavirus gastroenteritis in both developed and developing countries.

journal_name

Curr Opin Pediatr

authors

Dennehy PH

doi

10.1097/01.mop.0000147907.30720.04

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

88-92

issue

1

eissn

1040-8703

issn

1531-698X

pii

00008480-200502000-00018

journal_volume

17

pub_type

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