Therapeutic drug monitoring in inflammatory bowel disease.

abstract：PURPOSE OF REVIEW:Over 80% of children diagnosed with cancer are now cured. The burgeoning population of survivors of childhood cancer experiences high rates of morbidity and mortality due to 'late-effects' of treatment. These can be defined as any consequence of treatment that persists beyond or develops after the com...

journal_title：Current opinion in pediatrics

authors： Song A,Fish JD

更新日期：2018-12-01 00:00:00

abstract：:The Back to Sleep Campaigns remain the greatest influence on the reduction of sudden infant death syndrome. Blatt and Meguid review updates on the effectiveness of these campaigns in reducing sudden infant death syndrome. They also review studies on why parents do not follow this proven advice. The contribution of the...

journal_title：Current opinion in pediatrics

authors： Blatt SD,Meguid V,Church CC

更新日期：2000-04-01 00:00:00

abstract：:Nocturnal enuresis is a common problem occurring in 15% of children at 5 years of age. Although usually self-limiting, justification for early treatment is founded in the psychological impact on the child. The physician's role in treating enuresis is first to rule out structural causes for enuresis. After this has bee...

journal_title：Current opinion in pediatrics

authors： Gandhi KK

更新日期：1994-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Epidermolysis bullosa is a hereditary skin disorder characterized by skin fragility. However, the disease can manifest in many different organ systems, therefore children born with epidermolysis bullosa may have life long, complex medical needs. In this review, we will use a system-based approach to h...

journal_title：Current opinion in pediatrics

authors： Cohn HI,Teng JM

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing numbers of children are now traveling to high-altitude destinations, and pediatricians often see these children prior to and immediately following their travels. Thus, pediatricians have the opportunity to provide guidance for the prevention of altitude illness and must treat high-altitude ...

journal_title：Current opinion in pediatrics

authors： Garlick V,O'Connor A,Shubkin CD

更新日期：2017-08-01 00:00:00

abstract：:Risk factors for infant development are considered in three areas: infant temperament, postpartum depression, and prenatal cocaine exposure. Investigations of all three areas indicate that contextual characteristics of infant development must be incorporated into models attempting to link early risk factors with later...

journal_title：Current opinion in pediatrics

authors： Zeanah CH,Scheeringa M,Boris N

更新日期：1994-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Developmental speech and language disorders are common, seen in one in 20 preschool children, in the absence of frank neurological deficits or intellectual impairment. They are a key reason parents seek help from paediatricians. Complex neurogenetic and environmental contributions underpin the disorde...

journal_title：Current opinion in pediatrics

authors： Morgan A,Bonthrone A,Liégeois FJ

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent literature regarding assessment, management and prevention of child maltreatment will be considered. Unexplained infant and child death will also be reviewed. RECENT FINDINGS:Controversies in the evaluation of unexpected infant death and inflicted traumatic brain injury are ongoing. Evidence c...

journal_title：Current opinion in pediatrics

authors： Newton AW,Vandeven AM

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Atopic dermatitis, one of the most common chronic illnesses of childhood, is encountered routinely by all providers of health care to children. RECENT FINDINGS:In recent years there has been a dramatic rise in the prevalence of atopic dermatitis and therefore a rapid increase in the number of studies...

journal_title：Current opinion in pediatrics

authors： Sturgill S,Bernard LA

更新日期：2004-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to provide primary care physicians with updates on recent literature regarding clubfoot and answer questions asked by parents and caregivers of children with clubfoot. The topics discussed include prenatal counseling, relapse after Ponseti treatment, long-term outcomes following succe...

journal_title：Current opinion in pediatrics

authors： Yau A,Doyle SM

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Infantile spasms, mental retardation, autism, and dystonia represent disabling diseases for which little etiologic information is available. Mutations in the Aristaless related homeobox gene (ARX) have been found in patients with these conditions. This discovery provides important genetic information ...

journal_title：Current opinion in pediatrics

authors： Sherr EH

更新日期：2003-12-01 00:00:00

abstract：:Neonatal infections range from early-onset vertically acquired infections to nosocomial bacterial sepsis, and they account for significant morbidity and mortality globally. The recent emergence of perinatally acquired HIV-1 infection has also placed an enormous burden on existing meager health resources in developing ...

journal_title：Current opinion in pediatrics

authors： Bhutta ZA

更新日期：1997-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe current concepts on inflammation, immunity and insulin resistance. Metabolic and immune systems are closely involved in inflammation and significantly contribute to the pathology seen in the pediatric intensive care unit. The ability of insulin to decrease hep...

journal_title：Current opinion in pediatrics

authors： Dhar A,Castillo L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:We present data from recently conducted research regarding the diagnosis of blunt cervical spine injury (CSI) in children. RECENT FINDINGS:Research in the prehospital setting to evaluate the need for cervical spine immobilization in children, regardless of clinical findings or mechanism of injury, su...

journal_title：Current opinion in pediatrics

authors： Tilt L,Babineau J,Fenster D,Ahmad F,Roskind CG

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Extremely low gestational age newborns (ELGANs), born at less than 28 weeks' estimated gestational age, suffer the greatest consequences of prematurity. There have been significant advances in their care over the last several decades, but the prospects for major advances within traditional treatment m...

journal_title：Current opinion in pediatrics

authors： Davis RP,Bryner B,Mychaliska GB

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Children with chronic kidney disease (CKD) have impaired growth that leads to short stature in adulthood. The problem persists even with successful transplantation and steroid withdrawal protocols. The aim of this review is to provide an overview of the pressing issues related to growth failure in chi...

journal_title：Current opinion in pediatrics

authors： Ingulli EG,Mak RH

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Altered epigenetics is central to oncogenesis in many pediatric cancers. Aberrant epigenetic states are induced by mutations in histones or epigenetic regulatory genes, aberrant expression of genes regulating chromatin complexes, altered DNA methylation patterns, or dysregulated expression of noncodin...

journal_title：Current opinion in pediatrics

authors： Panditharatna E,Filbin MG

更新日期：2020-02-01 00:00:00

abstract：:Bacterial meningitis is an important problem in childhood. Vaccines can prevent Haemophilus influenzae type b disease and are being developed for infections caused by meningococci and pneumococci. Lumbar puncture is an important part of the diagnostic workup although care is required with its use. Once meningitis is d...

journal_title：Current opinion in pediatrics

authors： Booy R,Kroll S

更新日期：1994-02-01 00:00:00

abstract：:Atopic dermatitis is the most common chronic skin disease of young children and is frequently associated with asthma and allergies. Th2-type cytokine secreting T cells expressing the cutaneous lymphocyte-associated antigen play a central role in the induction of local IgE responses and recruitment of eosinophils in th...

journal_title：Current opinion in pediatrics

authors： Boguniewicz M

更新日期：1997-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent developments in the assessment of changes in structure and function in the fetal heart with the focus on congenital heart disease malformations. RECENT FINDINGS:Use of the combination of the cardiovascular profile score, the biophysical profile score and additional physiol...

journal_title：Current opinion in pediatrics

authors： Acharya G,Archer N,Huhta JC

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite improvements in surgical techniques, valvular regurgitation results in major morbidity in children with heart disease. Functional anatomy, mechanisms of valve closure and adaptation to changing hemodynamic stress in normal mitral and tricuspid valves are complex and only partially understood. ...

journal_title：Current opinion in pediatrics

authors： Khoo NS,Smallhorn JF

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:A variety of new indications for laser treatment have been raised in the dermatology field recently. They offer significant opportunities to manage a large spectrum of conditions in the pediatric population. Therefore, it is necessary to know the current trends and limitations of their use for the tre...

journal_title：Current opinion in pediatrics

authors： Cordisco MR

更新日期：2009-08-01 00:00:00

abstract：:Necrotizing enterocolitis is an overwhelming gastrointestinal emergency that primarily afflicts premature infants born weighing less than 1500 g. Despite years of investigation, the etiology remains unclear, and accepted prevention and treatment strategies are lacking. Studies published over the last year have provide...

journal_title：Current opinion in pediatrics

authors： Caplan MS,Jilling T

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize recent research regarding the diagnosis of allergic rashes and to suggest future directions for the promotion of accurate diagnosis and endotype specification. RECENT FINDINGS:Multiple cohort studies demonstrate that with appropriate clinical evaluation, dru...

journal_title：Current opinion in pediatrics

authors： Happel CS

更新日期：2017-06-01 00:00:00

abstract：:Genetic causes account for 20% to 25% of human birth defects, but the largest proportion of birth defects have no definitive etiology and some of these malformations may be due to intrinsic, "nonpreventable" spontaneous errors of development. Environmental causes, which include maternal disease states, maternal infect...

journal_title：Current opinion in pediatrics

authors： Brent RL,Beckman DA,Landel CP

更新日期：1993-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Osteogenic sarcoma, also known as osteosarcoma, is a primary malignancy of the bone in which spindle cells produce osteoid. Although rare in the general population, these tumors are the most common primary malignancies of bone and the fifth most common primary malignancy of adolescence. This paper aim...

journal_title：Current opinion in pediatrics

authors： Kim HJ,Chalmers PN,Morris CD

更新日期：2010-02-01 00:00:00

abstract：:A careful history and physical examination will help to differentiate between encopresis with or without constipation and fecal incontinence caused by anatomic or organic disease. Most children with encopresis with or without functional constipation require no or minimal laboratory workup. Successful treatment of enco...

journal_title：Current opinion in pediatrics

authors： Loening-Baucke V

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been an explosion in knowledge about celiac disease (CD) in the last decade based on the availability of serologic screening tests and the elucidation of some of the important disease susceptibility genes. What has been discovered is that CD is among the most common inherited diseases with a...

journal_title：Current opinion in pediatrics

authors： Treem WR

更新日期：2004-10-01 00:00:00

abstract：:The use of extracorporeal techniques for the treatment of pediatric diseases has expanded dramatically in the past decade. During this time, experience with both plasmapheresis and renal replacement therapy has become commonplace in ICUs and nephrology programs throughout the world. The indications for these therapies...

journal_title：Current opinion in pediatrics

authors： Bunchman TE

更新日期：2002-06-01 00:00:00

abstract：:This article reviews recent publications related to the epidemiology, pathogenesis, diagnosis, and management of otitis media. Otitis media is a continuum of conditions that includes acute otitis media, otitis media with residual or persistent effusion, unresponsive otitis media, recurrent otitis media, otitis media w...

journal_title：Current opinion in pediatrics

authors： Berman S

更新日期：1995-10-01 00:00:00