Atopic dermatitis update.

abstract：PURPOSE OF REVIEW:Altered epigenetics is central to oncogenesis in many pediatric cancers. Aberrant epigenetic states are induced by mutations in histones or epigenetic regulatory genes, aberrant expression of genes regulating chromatin complexes, altered DNA methylation patterns, or dysregulated expression of noncodin...

journal_title：Current opinion in pediatrics

authors： Panditharatna E,Filbin MG

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the current evidence on the use of infection markers for diagnostic evaluation of sepsis in neonates. RECENT FINDINGS:Recent research in immunology has led to the discovery of cell surface antigens, chemokines, cytokines and acute phase proteins that can potentially be used to 'rule in' or ...

journal_title：Current opinion in pediatrics

authors： Ng PC,Lam HS

更新日期：2006-04-01 00:00:00

abstract：:Attention-deficit hyperactivity disorder has been redefined in the classifications in the International Classification of Disease, 10th revision and Diagnostic and Statistical Manual of Mental Disorders, fourth edition. The definitions are more concordant than their predecessors and reemphasize the distinction between...

journal_title：Current opinion in pediatrics

authors： Baxter PS

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:SARS-CoV-2 is the novel human coronavirus responsible for the COVID19 pandemic. Accurate detection of infection with SARS-CoV-2 is an essential component of efforts to treat individual patients and to contain spread of the virus in the community. The purpose of this review is to describe current diagn...

journal_title：Current opinion in pediatrics

authors： Spearman P

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to explore the effects of the opioid crisis on pediatric patients in the postoperative setting and provide recommendations for well-tolerated opioid prescribing practices. RECENT FINDINGS:Opioid overdoses have increased among all age groups, predominantly related to over...

journal_title：Current opinion in pediatrics

authors： Harbaugh CM,Gadepalli SK

更新日期：2019-06-01 00:00:00

abstract：:Cutaneous reactions to penicillin-type antibiotics are usually caused by IgE-mediated reactions directed toward the beta-lactam ring (in penicillin, ampicillin-amoxicillin, and cephalosporins). These allergic reactions may be reliably diagnosed (96% to 99% of the time) with a battery of skin tests derived from penicil...

journal_title：Current opinion in pediatrics

authors： Anderson JA

更新日期：1994-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Abdominal wall defects comprising both gastroschisis and omphalocele remain a source of significant morbidity and mortality, despite the advances in neonatal and pediatric surgical care. Survival has improved over the past few decades, especially with parenteral nutrition and surgical repair. Yet, sti...

journal_title：Current opinion in pediatrics

authors： Islam S

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Radiation exposure from computed tomography is associated with a small but significant increase in risk for fatal cancer over a child's lifetime. This review aims to heighten awareness and spearhead efforts to reduce unnecessary computed tomography scans in children. RECENT FINDINGS:The use of pediat...

journal_title：Current opinion in pediatrics

authors： Shah NB,Platt SL

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe current concepts on inflammation, immunity and insulin resistance. Metabolic and immune systems are closely involved in inflammation and significantly contribute to the pathology seen in the pediatric intensive care unit. The ability of insulin to decrease hep...

journal_title：Current opinion in pediatrics

authors： Dhar A,Castillo L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will outline the screening, diagnosis and management of cystic fibrosis related diabetes (CFRD). It will also discuss advances in the detection of early glucose abnormalities, their clinical significance and the emerging role for early insulin therapy. RECENT FINDINGS:Before the onset of ...

journal_title：Current opinion in pediatrics

authors： Hameed S,Jaffé A,Verge CF

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:In many United States households, there are many substances used to control the exposure of our children to mosquitoes, mice and rats. This review provides information on common mosquito repellents and rodenticides used in households and discusses their toxicity, in order to help pediatricians better ...

journal_title：Current opinion in pediatrics

authors： Kendrick DB

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Ras pathway mutations are one of the most common type of alterations in pediatric hematologic malignancies and are frequently associated with adverse outcomes. Despite ongoing efforts to use targeted treatments, there remain no Food and Drug Administration (FDA)-approved medications specifically for c...

journal_title：Current opinion in pediatrics

authors： Pikman Y,Stieglitz E

更新日期：2021-02-01 00:00:00

abstract：:Tarsal coalition is a common abnormality of the hindfoot skeleton that only rarely leads to symptoms. These symptoms occur most commonly in adolescence but rarely can be found also in adults. Although most coalitions are congenital, as the consequence of autosomal dominant inheritance, coalitions also can be acquired ...

journal_title：Current opinion in pediatrics

authors： Bohne WH

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This update reviews the concepts underlying ethical issues in various contexts and countries, highlighting the evolution in the use of the core values underpinning the field and practice of bioethics as applied to healthcare. RECENT FINDINGS:It stresses the specific position of the adolescent as bein...

journal_title：Current opinion in pediatrics

authors： Michaud PA,Berg-Kelly K,Macfarlane A,Benaroyo L

更新日期：2010-08-01 00:00:00

abstract：:Bacterial meningitis is an important problem in childhood. Vaccines can prevent Haemophilus influenzae type b disease and are being developed for infections caused by meningococci and pneumococci. Lumbar puncture is an important part of the diagnostic workup although care is required with its use. Once meningitis is d...

journal_title：Current opinion in pediatrics

authors： Booy R,Kroll S

更新日期：1994-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Intrauterine growth restriction (IUGR) is associated with an increased propensity to develop adult-onset disease and is described by the developmental origins of adult disease hypothesis. Sequelae of fetal growth restriction include metabolic disease as well as nonmetabolic disorders. Although it has ...

journal_title：Current opinion in pediatrics

authors： Joss-Moore LA,Lane RH

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Gynecomastia is a common finding in adolescent men. The primary care provider should feel equipped to thoroughly evaluate this condition and to differentiate physiologic from pathologic breast enlargement. The present review focuses on the epidemiology, pathogenesis, evaluation, and treatment of gynec...

journal_title：Current opinion in pediatrics

authors： Nordt CA,DiVasta AD

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary vascular disease (PVD) complicates the course of many cardiovascular, pulmonary and other systemic diseases in children. The physiological sequelae (pulmonary hypertension and elevated pulmonary vascular resistance) can overwhelm the right ventricle and lead to circulatory collapse. Despite ...

journal_title：Current opinion in pediatrics

authors： Brown G,Humpl T

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight some of the advances in the way we think about rhabdomyosarcoma (RMS). Recent outcome and biological analyses have shifted the risk stratification and treatment paradigms for pediatric RMS. RECENT FINDINGS:The presence or absence of the FOXO1 translocation i...

journal_title：Current opinion in pediatrics

authors： Hawkins DS,Gupta AA,Rudzinski ER

更新日期：2014-02-01 00:00:00

abstract：:Large and unusually large von Willebrand factor (vWf) multimers may be responsible for systemic platelet aggregation in thrombotic thrombocytopenic purpura (TTP). This possibility is supported by studies that show deficient vWf-cleaving metalloproteinase and increased platelet-vWf binding during TTP episodes. In acute...

journal_title：Current opinion in pediatrics

authors： Baker KR,Moake JL

更新日期：2000-02-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been an explosion in knowledge about celiac disease (CD) in the last decade based on the availability of serologic screening tests and the elucidation of some of the important disease susceptibility genes. What has been discovered is that CD is among the most common inherited diseases with a...

journal_title：Current opinion in pediatrics

authors： Treem WR

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight recent advances in management of peanut allergy. RECENT FINDINGS:Peanut allergy presents during early childhood. The prevalence of peanut allergy in children in developed countries appears to be increasing. Several factors, such as peanut-specific or environmental, are hypothesized as co...

journal_title：Current opinion in pediatrics

authors： Pansare M,Kamat D

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:P450 oxidoreductase deficiency--a newly described form of congenital adrenal hyperplasia--typically presents a steroid profile suggesting combined deficiencies of steroid 21-hydroxylase and 17alpha-hydroxylase/17,20-lyase activities. These and other enzymes require electron donation from P450 oxidored...

journal_title：Current opinion in pediatrics

authors： Flück CE,Miller WL

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevalence of pediatric atopic dermatitis (AD) has increased throughout the world, now ranging from 10 to 20% in developed countries. Pediatric patients with AD make up a substantial proportion of patients seen by general pediatricians, allergists, dermatologists, and other specialists. As such, t...

journal_title：Current opinion in pediatrics

authors： Totri CR,Diaz L,Eichenfield LF

更新日期：2014-08-01 00:00:00

abstract：:Stachybotrys is a toxin-producing fungus that grows indoors when both water and cellulose are available. Epidemiologic evidence has demonstrated an association between acute pulmonary hemorrhage in infants and exposure to Stachybotrys and other fungi in water-damaged home environments. In recent years, advances in und...

journal_title：Current opinion in pediatrics

authors： Etzel RA

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Infantile spasms, mental retardation, autism, and dystonia represent disabling diseases for which little etiologic information is available. Mutations in the Aristaless related homeobox gene (ARX) have been found in patients with these conditions. This discovery provides important genetic information ...

journal_title：Current opinion in pediatrics

authors： Sherr EH

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The clinical importance of overgrowth syndromes in the pediatric patient population has been increasingly recognized during the past decade, but clinical overlap among overgrowth syndromes often makes diagnostic categorization difficult. Advances in the molecular delineation of overgrowth syndromes in...

journal_title：Current opinion in pediatrics

authors： Cytrynbaum CS,Smith AC,Rubin T,Weksberg R

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:First-time parents often turn to friends and family for advice regarding feeding, sleeping, bathing, diapering and toilet training, and childhood illnesses. Unfortunately, parents may at times be given incorrect and potentially dangerous advice as several widely embraced parenting practices are no lon...

journal_title：Current opinion in pediatrics

authors： Kahan T,Adesman A

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Diaper dermatitis is the most common cutaneous diagnosis in infants. In this review, common causes of diaper dermatitis and similarly presenting conditions will be covered, as well as updates on treatments of common diaper dermatitides. RECENT FINDINGS:There have been recent advancements in the treat...

journal_title：Current opinion in pediatrics

authors： Ravanfar P,Wallace JS,Pace NC

更新日期：2012-08-01 00:00:00

abstract：:Miniaturization of echocardiographic transducers, improved crystal technology, and enhanced digital processing of ultrasound signals have resulted in newer, more sophisticated equipment and imaging techniques. These technologic advances include transesophageal echocardiography, stress echocardiography (both pharmacolo...

journal_title：Current opinion in pediatrics

authors： Marx GR

更新日期：1995-10-01 00:00:00