What is new in the biology and treatment of pediatric rhabdomyosarcoma?

abstract：PURPOSE OF REVIEW:SARS-CoV-2 is the novel human coronavirus responsible for the COVID19 pandemic. Accurate detection of infection with SARS-CoV-2 is an essential component of efforts to treat individual patients and to contain spread of the virus in the community. The purpose of this review is to describe current diagn...

journal_title：Current opinion in pediatrics

authors： Spearman P

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The clinical importance of overgrowth syndromes in the pediatric patient population has been increasingly recognized during the past decade, but clinical overlap among overgrowth syndromes often makes diagnostic categorization difficult. Advances in the molecular delineation of overgrowth syndromes in...

journal_title：Current opinion in pediatrics

authors： Cytrynbaum CS,Smith AC,Rubin T,Weksberg R

更新日期：2005-12-01 00:00:00

abstract：:Dyslipidemia increases the risk of cardiovascular events among individuals with renal disease, and there is a growing body of evidence that it hastens the progression of renal disease itself. Children with nephrotic syndrome or renal transplants have easily recognized hyperlipidemia. Among those with chronic renal ins...

journal_title：Current opinion in pediatrics

authors： Saland JM,Ginsberg H,Fisher EA

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:P450 oxidoreductase deficiency--a newly described form of congenital adrenal hyperplasia--typically presents a steroid profile suggesting combined deficiencies of steroid 21-hydroxylase and 17alpha-hydroxylase/17,20-lyase activities. These and other enzymes require electron donation from P450 oxidored...

journal_title：Current opinion in pediatrics

authors： Flück CE,Miller WL

更新日期：2006-08-01 00:00:00

abstract：:A constant in the practice of general pediatrics is an emphasis on infant nutrition and monitoring of growth. These topics are the focus of this issue's "Office pediatrics" section. Much of the new research and publication concerning nutrition in childhood in the past year continues to focus on breastfeeding-its short...

journal_title：Current opinion in pediatrics

authors： Rider E,Samuels R,Wilson K,Homer C

更新日期：1996-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic rhinitis, conjunctivitis, and asthma impact quality of life and cost billions of dollars in lost wages, productivity, and medical expenditures. Allergen immunotherapy is the only therapy that alters the allergen immune response, resulting in fewer symptoms upon natural exposure. This review s...

journal_title：Current opinion in pediatrics

authors： Vadlamudi A,Shaker M

更新日期：2015-10-01 00:00:00

abstract：:Inhaled corticosteroids (ICS) have become the mainstay of therapy in chronic childhood asthma. Despite the long history and the documented efficacy of these drugs in controlling asthma, concerns still abound regarding the safety of these drugs in children, most specifically related to the potential for adrenal suppres...

journal_title：Current opinion in pediatrics

authors： Bazzy-Asaad A

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will be covering dysfunctional voiding, its diagnosis, and treatment options. This will focus primarily on dysfunctional voiding rather than all lower urinary tract dysfunction and we will focus on some of the newer findings and progress within this disease. RECENT FINDINGS:Dysfunctional ...

journal_title：Current opinion in pediatrics

authors： Bauer A

更新日期：2020-12-10 00:00:00

abstract：PURPOSE OF REVIEW:Over 80% of children diagnosed with cancer are now cured. The burgeoning population of survivors of childhood cancer experiences high rates of morbidity and mortality due to 'late-effects' of treatment. These can be defined as any consequence of treatment that persists beyond or develops after the com...

journal_title：Current opinion in pediatrics

authors： Song A,Fish JD

更新日期：2018-12-01 00:00:00

abstract：:Smoking prevention during childhood and adolescence is critical to the successful reduction of tobacco-related morbidity and mortality in the United States. The research literature is replete with surveys describing youth smoking acquisition and related factors. In addition to its direct harm, tobacco use may be a gat...

journal_title：Current opinion in pediatrics

authors： Sockrider MM

更新日期：1997-06-01 00:00:00

abstract：:Treatment of patients with anorexia nervosa is a topic that continues to spark debate. Two particular areas of controversy include the role of exercise and the use of selective serotonergic reuptake inhibitors (SSRI). Few randomized controlled trials have addressed these two issues. The psychological impact of exercis...

journal_title：Current opinion in pediatrics

authors： Rosenblum J,Forman SF

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight recent advances in management of peanut allergy. RECENT FINDINGS:Peanut allergy presents during early childhood. The prevalence of peanut allergy in children in developed countries appears to be increasing. Several factors, such as peanut-specific or environmental, are hypothesized as co...

journal_title：Current opinion in pediatrics

authors： Pansare M,Kamat D

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Femoroacetabular impingement (FAI) post slipped capital femoral epiphysis (SCFE) may lead to degenerative changes on the hip. We have reviewed the current procedures in the literature, aiming to correct the SCFE to prevent FAI and the ones that treat FAI post SCFE. RECENT FINDINGS:The trends of manag...

journal_title：Current opinion in pediatrics

authors： Soni JF,Valenza WR,Uliana CS

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Recently, recommendations from the American Heart Association regarding treatment of streptococcal tonsillo-pharyngitis were revised. This review provides the background for changes that were made in comparison with the group's 1995 recommendations. Recent papers on other issues relating to group A St...

journal_title：Current opinion in pediatrics

authors： Baltimore RS

更新日期：2010-02-01 00:00:00

abstract：:In the recent past, we have seen novel information on the bidirectional interactions between the endocrine and immune systems. Thus, the central nervous system, through the hypothalamic-pituitary-adrenal axis and the peripheral autonomic and sensory systems, influences the quantity and the quality of the immune and in...

journal_title：Current opinion in pediatrics

authors： Papanicolaou DA,Chrousos GP

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to review advances in both the pathogenesis and clinical management of biliary atresia. RECENT FINDINGS:Immunologic studies have further characterized roles of helper T-cells, B-cells, and natural killer cells in the immune dysregulation following viral replication within...

journal_title：Current opinion in pediatrics

authors： Zagory JA,Nguyen MV,Wang KS

更新日期：2015-06-01 00:00:00

abstract：:Risk factors for infant development are considered in three areas: infant temperament, postpartum depression, and prenatal cocaine exposure. Investigations of all three areas indicate that contextual characteristics of infant development must be incorporated into models attempting to link early risk factors with later...

journal_title：Current opinion in pediatrics

authors： Zeanah CH,Scheeringa M,Boris N

更新日期：1994-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Spondylolysis is a common cause for back pain in the adolescent athlete. Increased awareness of the presentation of this subset of patients can aid in optimal outcomes. This paper aims to review the typical presentation of spondylolysis in the adolescent with specific focus on the adolescent athlete. ...

journal_title：Current opinion in pediatrics

authors： Kim HJ,Green DW

更新日期：2011-02-01 00:00:00

abstract：:Food allergy or hypersensitivity is defined as an adverse reaction to food protein which is immune mediated. Without standard definitions and reliable tests for many forms of allergic disease of the bowel, studies are difficult to interpret. The proceedings of a recent workshop on the classification of adverse immunol...

journal_title：Current opinion in pediatrics

authors： Justinich CJ

更新日期：2000-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent advances in severe congenital neutropenia (SCN) syndromes. RECENT FINDINGS:The majority of patients with SCN bear monoallelic mutations in the neutrophil elastase (ELANE) gene. Biallelic mutations in the antiapoptotic gene HAX1 were identified in patients with autosomal recessive SCN...

journal_title：Current opinion in pediatrics

authors： Boztug K,Klein C

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:A brief delay in clamping the umbilical cord after birth offers health benefits to the newborn, with no adverse effects to the mother or her infant. Yet, in most obstetric practice, the cord is clamped soon after birth. A summary of the current evidence on delayed cord clamping and some reasons for th...

journal_title：Current opinion in pediatrics

authors： Raju TN

更新日期：2013-04-01 00:00:00

abstract：:von Willebrand disease (VWD) is a bleeding disorder caused by quantitative (type 1 and 3) or qualitative (type 2) defects of von Willebrand factor (VWF). The mechanisms of most inherited VWD types have been recently elucidated by genetic and molecular diagnosis, but the phenotypic tests based on measurements of plasma...

journal_title：Current opinion in pediatrics

authors： Federici AB,Mannucci PM

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This paper reviews recent publications about the physiology associated with adaptation to malnutrition and refeeding (including the refeeding syndrome) and clinical outcomes of refeeding paradigms. RECENT FINDINGS:A number of recent reviews and original publications have highlighted important differe...

journal_title：Current opinion in pediatrics

authors： Kohn MR,Madden S,Clarke SD

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Enhanced recovery protocols (ERPs) have been adopted for a variety of adult surgical conditions and resulted in markedly improved outcomes, including decreased length of stays, complications, costs, and narcotic utilization. In this review, we describe the development and implementation of an ERP for ...

journal_title：Current opinion in pediatrics

authors： Raval MV,Heiss KF

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a current review of recent publications with regards to intracranial hypertension. RECENT FINDINGS:Attempts were made to provide pediatric data; however, the recent completion of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) has provided a wealth of data with regards to ...

journal_title：Current opinion in pediatrics

authors： Jordan CO,Aylward SC

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The term 'dual diagnosis' most commonly refers to the combination of severe mental illness and substance-use disorder (SUD). It is estimated that 7-10 million people in the USA alone have at a minimum one psychiatric disorder in addition to a SUD. As many of the psychiatric illnesses implicated have t...

journal_title：Current opinion in pediatrics

authors： Santucci K

更新日期：2012-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Gynecomastia is a common finding in adolescent men. The primary care provider should feel equipped to thoroughly evaluate this condition and to differentiate physiologic from pathologic breast enlargement. The present review focuses on the epidemiology, pathogenesis, evaluation, and treatment of gynec...

journal_title：Current opinion in pediatrics

authors： Nordt CA,DiVasta AD

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:We present data from recently conducted research on the diagnosis and management of skin and soft tissue infections (SSTIs) in children. RECENT FINDINGS:Current research in the area of SSTIs (cellulitis and abscess) has focused on the use of ultrasound, risk factors associated with bacteremia, antibi...

journal_title：Current opinion in pediatrics

authors： Fenster DB,Renny MH,Ng C,Roskind CG

更新日期：2015-06-01 00:00:00

abstract：:A 10-month-old infant with multiple infantile hepatic hemangiomas and developmental delay is reported. He was found to be profoundly hypothyroid. Evaluation and management issues are discussed. This case emphasizes the importance of screening for hypothyroidism in patients with hemangiomas and the potential therapeuti...

journal_title：Current opinion in pediatrics

authors： Cho YH,Taplin C,Mansour A,Howman-Giles R,Hardwick R,Lord D,Howard NJ

更新日期：2008-04-01 00:00:00

abstract：:The biology of the X chromosome is unique, as there are two Xs in females and only a single X in males, whereas the autosomes are present in duplicate in both sexes. The presence of only a single autosome, which can occur as a result of an error in meiotic segregation, is invariably an embryonic lethal event. Monosomy...

journal_title：Current opinion in pediatrics

authors： Gartler SM,Goldman MA

更新日期：2001-08-01 00:00:00