Quality improvement in pediatric surgery.

abstract：PURPOSE OF REVIEW:This study reviews the history of neonatal drug development, recent legislative efforts designed to facilitate the study of therapeutic agents in neonates, and future steps necessary to advance drug development. RECENT FINDINGS:Although many federal regulations have been introduced over the past 15 y...

journal_title：Current opinion in pediatrics

authors： Smith AM,Davis JM

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Adolescents, in particular those that are most disenfranchised, are increasingly at risk of acquiring HIV and, when acquiring HIV, have worse outcomes than adults. This article reviews the recent approaches to combination prevention aiming to optimize the HIV prevention and HIV treatment continua. RE...

journal_title：Current opinion in pediatrics

authors： Rotheram-Borus MJ,Davis E,Rezai R

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Ras pathway mutations are one of the most common type of alterations in pediatric hematologic malignancies and are frequently associated with adverse outcomes. Despite ongoing efforts to use targeted treatments, there remain no Food and Drug Administration (FDA)-approved medications specifically for c...

journal_title：Current opinion in pediatrics

authors： Pikman Y,Stieglitz E

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The mid-gestation fetus is capable of regenerative healing with wound healing indistinguishable from surrounding skin. This review aims to evaluate the current knowledge of how the mid-gestation fetus heals without scar and the implications of these findings in efforts to recapitulate the fetal regene...

journal_title：Current opinion in pediatrics

authors： Leung A,Crombleholme TM,Keswani SG

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Describe developments in the etiological understanding of Tourette syndrome. RECENT FINDINGS:Tourette syndrome is a complex heterogenous clinical syndrome, which is not a unitary entity. Pathophysiological models describe gamma-aminobutyric acid-ergic-associated disinhibition of cortico-basal ganglia...

journal_title：Current opinion in pediatrics

authors： Dale RC

更新日期：2017-12-01 00:00:00

abstract：:Guidelines are an increasingly prominent part of the practice of pediatrics. Aiming from studies of variability in care, they are widely used as a mechanism to assess and improve quality. Rigorous methods of guideline development differentiate current guidelines from past consensus efforts. The American Academy of Ped...

journal_title：Current opinion in pediatrics

authors： Homer CJ,Grossman RG,Rodman J

更新日期：1996-10-01 00:00:00

abstract：:Dietary long-chain polyunsaturated fatty acids have demonstrable beneficial effects on early development. The effects on neural development are of particular interest. Human milk is the best and only time-proven source of fat and essential fatty acids in the infant diet. Technologic procedures based on chemical and ph...

journal_title：Current opinion in pediatrics

authors： Uauy R,Mena P

更新日期：1999-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Complement mediated hemolytic uremic syndrome (aHUS) accounts for a significant proportion of non-shiga toxin HUS. The purpose of this review is to outline the pathophysiology, clinical features and therapeutic options for aHUS. RECENT FINDINGS:In the last decade, strides have been made in identifyin...

journal_title：Current opinion in pediatrics

authors： Joseph C,Gattineni J

更新日期：2013-04-01 00:00:00

abstract：:A constant in the practice of general pediatrics is an emphasis on infant nutrition and monitoring of growth. These topics are the focus of this issue's "Office pediatrics" section. Much of the new research and publication concerning nutrition in childhood in the past year continues to focus on breastfeeding-its short...

journal_title：Current opinion in pediatrics

authors： Rider E,Samuels R,Wilson K,Homer C

更新日期：1996-06-01 00:00:00

abstract：:Abdominal imaging continues to grow in importance for diagnosis, anatomic staging, and functional analysis of gastrointestinal ailments. In this review, we attempt to delineate those publications, both original investigations and summary articles, that have advanced our understanding of abdominal imaging in infants an...

journal_title：Current opinion in pediatrics

authors： Kao SC,Franken EA Jr

更新日期：1996-10-01 00:00:00

abstract：:The importance of pediatric interhospital transport has increased dramatically in the past 5 to 10 years. Reasons include improved capabilities of tertiary care centers receiving transported patients, advances in availability of portable equipment that functions well in moving vehicles, and widespread recognition that...

journal_title：Current opinion in pediatrics

authors： McCloskey KA

更新日期：1996-06-01 00:00:00

abstract：:Genetic causes account for 20% to 25% of human birth defects, but the largest proportion of birth defects have no definitive etiology and some of these malformations may be due to intrinsic, "nonpreventable" spontaneous errors of development. Environmental causes, which include maternal disease states, maternal infect...

journal_title：Current opinion in pediatrics

authors： Brent RL,Beckman DA,Landel CP

更新日期：1993-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyskeratosis congenita, a rare condition characterized by mucocutaneous abnormalities and bone marrow failure, is caused by inherited defects in the telomerase complex. Autosomal dominant dyskeratosis congenita is associated with mutations in the RNA component of telomerase, hTERC, while X-linked dysk...

journal_title：Current opinion in pediatrics

authors： Bessler M,Wilson DB,Mason PJ

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Continuous glucose monitoring (CGM) is increasingly used in the management of diabetes in children and adults, but there are few data regarding its use in neonates. The purpose of this article is to discuss the potential benefits and limitations of CGM in neonates. RECENT FINDINGS:Smaller electrodes ...

journal_title：Current opinion in pediatrics

authors： Shah R,McKinlay CJD,Harding JE

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In September 2019, the United States was at risk of losing measles elimination status due to several large-scale outbreaks resulting in more than 1200 confirmed cases across 31 states. This resurgence caps approximately 10 years of increasing incidence, marked by a highly publicized outbreak in 2015 a...

journal_title：Current opinion in pediatrics

authors： Feemster KA,Szipszky C

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Considerable attention has recently been focused on the pathogenesis, diagnosis and treatment of osteogenesis imperfecta. Two new genes have been defined in patients with recessive severe or lethal osteogenesis imperfecta types. Diagnostic concerns involve testing procedures, either skin biopsies or D...

journal_title：Current opinion in pediatrics

authors： Shapiro JR,Sponsellor PD

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current work investigating the neural bases of autism spectrum disorder (ASD) within the discipline of electrophysiological brain research. The manuscript focuses primarily on advances in understanding related to social information processing and interconnectivity among brain syst...

journal_title：Current opinion in pediatrics

authors： McPartland JC,Coffman M,Pelphrey KA

更新日期：2011-12-01 00:00:00

abstract：:Smoking prevention during childhood and adolescence is critical to the successful reduction of tobacco-related morbidity and mortality in the United States. The research literature is replete with surveys describing youth smoking acquisition and related factors. In addition to its direct harm, tobacco use may be a gat...

journal_title：Current opinion in pediatrics

authors： Sockrider MM

更新日期：1997-06-01 00:00:00

abstract：:Three main factors are needed for an infant to develop allergy: allergen exposure, a genetic predisposition, and contributory factors. Recent literature suggests that the incidence of in utero sensitization might have been underestimated up to now. A number of papers provide evidence that atopic dermatitis should be r...

journal_title：Current opinion in pediatrics

authors： Vandenplas Y

更新日期：1993-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Lyme disease, caused by Borrelia burgdorferi, is the most common vector-borne illness in the United States. The pathogenesis, ecology, and epidemiology of Lyme disease have been well described, and antimicrobial treatment is very effective. There has been controversy about whether infection can persis...

journal_title：Current opinion in pediatrics

authors： Oliveira CR,Shapiro ED

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:We present data from recently conducted research regarding the diagnosis of blunt cervical spine injury (CSI) in children. RECENT FINDINGS:Research in the prehospital setting to evaluate the need for cervical spine immobilization in children, regardless of clinical findings or mechanism of injury, su...

journal_title：Current opinion in pediatrics

authors： Tilt L,Babineau J,Fenster D,Ahmad F,Roskind CG

更新日期：2012-06-01 00:00:00

abstract：:Studies using movement analysis confirm that multiple soft tissue releases improve function in the ambulant child with cerebral palsy, and highlight the fine adjustments of ankle-foot orthosis, which benefit children with myelomeningocele. For both of these disorders, there is information with regard to hip subluxatio...

journal_title：Current opinion in pediatrics

authors： Roberts A,Evans GA

更新日期：1993-06-01 00:00:00

abstract：:This paper reviews recent studies of attention deficit-hyperactivity disorder, focusing on research with implications for adolescents. Only 10 of the 31 recent investigations discussed employed an exclusively adolescent sample, necessitating considerable extrapolation from studies of children or adults or mixed sample...

journal_title：Current opinion in pediatrics

authors： Phillips S,Soffer SL

更新日期：1996-08-01 00:00:00

abstract：:Acute bacterial rhinosinusitis is an infection of the nasal epithelium and paranasal sinus mucosa, usually caused in children by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and, less frequently, group A Streptococcus species. The clinical diagnosis is based on daytime cough that may be wor...

journal_title：Current opinion in pediatrics

authors： Conrad DA,Jenson HB

更新日期：2002-02-01 00:00:00

abstract：:Large and unusually large von Willebrand factor (vWf) multimers may be responsible for systemic platelet aggregation in thrombotic thrombocytopenic purpura (TTP). This possibility is supported by studies that show deficient vWf-cleaving metalloproteinase and increased platelet-vWf binding during TTP episodes. In acute...

journal_title：Current opinion in pediatrics

authors： Baker KR,Moake JL

更新日期：2000-02-01 00:00:00

abstract：:Herbal medicaments are in common use. In general, the judicious use of carefully selected and prepared herbal medications seems to cause few adverse effects and may be beneficial. However, toxic effects of these products have been reported with increasing frequency. Infants and children may be even more susceptible to...

journal_title：Current opinion in pediatrics

authors： Tomassoni AJ,Simone K

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Environmental factors, such as drugs, chemicals, or abnormal concentrations of natural metabolites, induce birth defects. Environmental effects on cardiogenesis have been little studied in contrast to neurogenesis. This review presents evidence on three environmental factors: alcohol, the drug lithium...

journal_title：Current opinion in pediatrics

authors： Linask KK,Huhta J

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will outline the screening, diagnosis and management of cystic fibrosis related diabetes (CFRD). It will also discuss advances in the detection of early glucose abnormalities, their clinical significance and the emerging role for early insulin therapy. RECENT FINDINGS:Before the onset of ...

journal_title：Current opinion in pediatrics

authors： Hameed S,Jaffé A,Verge CF

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has become increasingly important as a cause of skin and soft tissue infections (SSTIs), particularly abscesses, in patients seen in the emergency department setting. The antibiotic sensitivity profile of Staphylococcus aureus ...

journal_title：Current opinion in pediatrics

authors： Odell CA

更新日期：2010-06-01 00:00:00

abstract：:Disruptive behavior disorders present grave complications to normal childhood development. Their presence is frequently associated with additional psychiatric disorders. The hallmark features of the disruptive behavior disorders range from noncompliance to aggressive hostility toward authorities or peers. Oppositional...

journal_title：Current opinion in pediatrics

authors： Harden PW,Zoccolillo M

更新日期：1997-08-01 00:00:00