Abstract：
:Ingestion of an unknown quantity of Ludiomil (maprotiline)-costed tablets in a suicide is described. Although maprotiline is known for over 20 years now, relatively few cases of intoxications due to maprotiline overdose have been reported. The authors report a new and quick method to analyze and determine maprotiline and N-desmethylmaprotiline concentration in body fluids and postmortem specimens. The analytes and an internal standard (amitriptyline) were extracted from alkalinized samples into ethyl acetate before GC-NPD analysis. The proposed method resulted in a rapid procedure most useful in cases of deliberate poisoning with the tetracyclic antidepressant drug Ludiomil.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Keller T,Zollinger Udoi
10.1016/s0379-0738(97)00064-9subject
Has Abstractpub_date
1997-08-04 00:00:00pages
117-23issue
2eissn
0379-0738issn
1872-6283pii
S0379-0738(97)00064-9journal_volume
88pub_type
杂志文章abstract：:Clinical and research-based tests in molecular biology require a substantial amount of DNA and RNA, unfortunately, a considerable number of cells is needed for this amount of sample. Blood is one of the best and easiest source of cells, but is not used due to its invasive drawing methods and the needed volume. Another...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.109931
更新日期：2019-10-01 00:00:00
abstract：:An improved technique for cocaine extraction from urine samples for gas chromatographic (GC) analysis is described. Employing a simple liquid-liquid extraction (LLE) of cocaine with a mixture of ethyl ether:isopropanol (9:1) the method presents a mean recovery of 74.49%. Limit of detection (LOD) and limit of quantific...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00124-x
更新日期：2002-07-17 00:00:00
abstract：:In this study, the use of benchtop NMR spectroscopy in the analysis of solids and liquids used and/or produced during the HI reduction of pseudoephedrine was evaluated. The study focused on identifying organic precursors and phosphorus containing compounds used in and/or produced during the manufacturing process. Samp...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.06.026
更新日期：2017-09-01 00:00:00
abstract：:A study of the quantities of cocaine on banknotes in general circulation was conducted to investigate regional variations across England and Wales. No meaningful support was found for the proposition that there is regional variation in the quantities of cocaine in banknotes in general circulation in England and Wales....
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2016.10.017
更新日期：2017-01-01 00:00:00
abstract：:Forensic science is increasingly relied on by police and the courts to exonerate the innocent and to establish links to crime. With this increased reliance the potential for unjust outcomes increases, especially in serious matters for two reasons. The more serious the matter, the more likely that evidence mishandling ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.10.032
更新日期：2013-07-10 00:00:00
abstract：:In developed countries, sudden infant death syndrome (SIDS) represents the most prevalent cause of death in children between 1 month and 1 year of age. SIDS is a diagnosis of exclusion, a negative autopsy which requires the absence of structural organ disease. Although investigators have confirmed that a significant p...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.01.018
更新日期：2012-06-10 00:00:00
abstract：:A 23-year-old man was found on a raised hide in lying position, the head wrapped in a plastic bag connected with a helium gas cylinder by a polypropylene tube. The autopsy did not show any specific findings nor did the routine toxicological analysis reveal significant information regarding the cause of death (BAC 0.9 ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2007.03.027
更新日期：2007-08-06 00:00:00
abstract：:Capillary electrophoresis, the modern approach to instrumental electrophoresis, is probably the most rapidly expanding analytical technique that has appeared in recent years. In the hands of forensic toxicologists, capillary electrophoresis (CE) represents a powerful new analytical tool, which has proved suitable for ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(94)01612-9
更新日期：1995-01-05 00:00:00
abstract：:There are many techniques available for the recovery of fingermarks at scenes of crime including the possibility of taking casts of the marks. Casts can be advantageous in cases where other destructive recovery techniques might not be suitable, such as when recovering finger marks deposited on valued or immobile items...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2008.04.001
更新日期：2008-07-04 00:00:00
abstract：:Organised criminality is a great concern for national/international security. The demonstration of complex crimes is increasingly dependant on knowledge distributed within law-enforcement agencies and scientific disciplines. This separation of knowledge creates difficulties in reconstructing and prosecuting such crime...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.06.032
更新日期：2007-04-11 00:00:00
abstract：:The systematic exhumation of mass graves is becoming a frequent occurrence globally. Historically, it has been mostly anthropologists with their particular expertise in osteology that have been engaged by non-governmental organizations (NGO) to monitor mass grave exhumations and postmortem examinations, conducted by a...
journal_title：Forensic science international
pub_type： 指南,杂志文章
doi：10.1016/s0379-0738(03)00124-5
更新日期：2003-07-08 00:00:00
abstract：:Body components of aviation accident fatalities are often scattered, disintegrated, commingled, contaminated, and/or putrefied at accident scenes. These situations may impose difficulties in victim identification/tissue matching. The prevalence of misidentification in relation to aviation accident forensic toxicology ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2010.06.024
更新日期：2011-03-20 00:00:00
abstract：:The Forensic Anthropology Service of the Medical Examiner's Office of Porto Alegre was created in September 1997 to examine human skeletons, establish identification and identify lesions that may explain death. From September 1997 to December 2006, 344 skeletons were examined (mean: 37 examinations/year), and 322 were...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2008.05.004
更新日期：2008-08-06 00:00:00
abstract：:Petechial haemorrhages of the conjunctivae are not specific for lethal throttling or strangulation, but they belong to the important indicators for such mechanisms. In experimental models it is shown that petechial bleedings of the conjunctivae disappear with the occurrence of advanced signs of putrefaction or in case...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(94)90243-7
更新日期：1994-01-01 00:00:00
abstract：:We describe two cases of human consumption of seeds from Argyreia nervosa (Hawaiian Baby Woodrose), which resulted in one fatality due to falling from a building and one surviving witness. The principal psychoactive constituent of the seeds, lysergamide (LSA), was recovered from blood and urine samples by mixed-mode c...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.11.017
更新日期：2010-04-15 00:00:00
abstract：:A urine screening in fatalities with an unnatural or unknown cause of death (13-40 years of age) was carried out to evaluate the proportion of undetected drug-related cases. Ten out of 160 fatalities without a hint of drug consumption were classified as drug-related according to the definition of the Bundeskriminalamt...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(93)90062-f
更新日期：1993-11-01 00:00:00
abstract：:A liquid chromatography/tandem mass spectrometry method with solid phase extraction for the detection and the quantitation of flufenoxuron in an aliquot of blood was developed and validated. Flufenoxuron belongs to a benzoylurea insecticide and is the active ingredient of Cascade™. The analyte in postmortem specimens ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.07.041
更新日期：2015-12-01 00:00:00
abstract：:Due to the different types and quality of forensic evidence materials, their DNA content can vary substantially, and particularly low quantities can impact the results in an identification analysis. In this study, the quantity of mitochondrial and nuclear DNA was determined in a variety of materials using a previously...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.11.024
更新日期：2006-12-01 00:00:00
abstract：:The aim of our study was to evaluate differences between males and females based on patterns of costal cartilage ossification and also with respect to ageing. We provided diagnosis of ossifications from two files of radiograms. The first group consisted of 1044 chest and abdominal radiograms of patients (537 men and 5...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.06.009
更新日期：2009-10-30 00:00:00
abstract：:Many Y-chromosomal single nucleotide polymorphisms (SNPs) are now available. The haplogroups which they define are highly non-randomly distributed among populations, and could contribute much to population-of-origin prediction from DNA. If this potential is to be exploited in forensic analysis, high-throughput, parall...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(01)00385-1
更新日期：2001-05-15 00:00:00
abstract：:Fingerprint detection and Short Tandem Repeat (STR) typing are two approaches used for identification of individuals. The main goal of forensic laboratories is the development of a standardized protocol to obtain an STR profile from latent fingerprints, by typing the DNA transferred onto touched objects. The results o...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.109905
更新日期：2019-09-01 00:00:00
abstract：:Sharp force trauma (SFT) in bone and cartilage has been studied extensively. This literature review summarizes knife and saw mark research. Researchers have documented several features of cut surfaces and successfully associated them with various tool characteristics. Most study designs are based on light microscopic ...
journal_title：Forensic science international
pub_type： 杂志文章,评审
doi：10.1016/j.forsciint.2019.03.035
更新日期：2019-06-01 00:00:00
abstract：:Albumin concentration in cerebrospinal fluid (CSF) and plasma was determined in 44 cadavers divided into three groups on the basis of death agony duration. The same was determined in a control group of 42 patients with no demonstrable neurological disease. Following Schuller's method, the evaluation of the blood CSF b...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(83)90007-5
更新日期：1983-08-01 00:00:00
abstract：:Genotype and distribution of allele frequencies at 17 STRs were studied in 526 unrelated Japanese individuals using the PowerPlex 16 system and the AmpFlSTR Identifiler. ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(03)00075-6
更新日期：2003-05-05 00:00:00
abstract：:Phentermine capsules labelled Ionamin were suspected of being counterfeit. Examination of the contents revealed no phentermine, but caffeine and phenylpropanolamine. The usual microcrystalline and spectrodensitometry was used to confirm results of spectrophotometric identity tests. ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(83)90144-5
更新日期：1983-11-01 00:00:00
abstract：:Fifteen autosomal short tandem repeat (STR) markers (D3S1358, HUMTH01, D21S11, D18S51, PENTA E, D5S818, D13S317, D7S820, D16S539, CSF1PO, PENTA D, HUMvWA, D8S1179, HUMTPOX, FGA) were analyzed in 1734 individuals living in urban areas of cities from six different Argentinian provinces (Buenos Aires, Neuquén, Tucumán, L...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.02.042
更新日期：2007-01-05 00:00:00
abstract：:In vitro evaluation of the effect of five insecticidal phosphoric and 11 thiophosphoric acid esters on different, non-specific human leukocytes esterases indicated that most of the organic phosphor compounds studied inhibited the activity of neutral alpha-naphthylacetate esterase, alpha-naphthylbutyryl esterase, and n...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(84)90192-0
更新日期：1984-07-01 00:00:00
abstract：:We present two non fatal cases of intoxication with carbofuran (CBF) documented by hair analysis. Carbofuran and 3-hydroxycarbofuran (OHCBF, its main metabolite) hair concentrations were determined using a liquid chromatography-tandem mass spectrometry method. The obtained results were surprising if we consider severa...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2011.05.011
更新日期：2011-10-10 00:00:00
abstract：:Determining the sequencing of intersecting ink lines is one of the current problems for forensic document examiners. The way two inks will distribute and interact with each other and the paper at the crossing is a dynamic process that can be affected by many variables. Thus, the main purpose of this manuscript is to v...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2013.10.026
更新日期：2014-01-01 00:00:00
abstract：:Dental forensic identifications based on comparison of antemortem and postmortem radiographs provide effective and reliable evidence. There are no standardized procedures for assessing similarities between different types of dental radiographs (e.g. orthopantomograms, bitewings, and periapical radiographs), and the op...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.06.015
更新日期：2012-10-10 00:00:00
