Surprising hair analysis results following acute carbofuran intoxication.

Abstract:

:We present two non fatal cases of intoxication with carbofuran (CBF) documented by hair analysis. Carbofuran and 3-hydroxycarbofuran (OHCBF, its main metabolite) hair concentrations were determined using a liquid chromatography-tandem mass spectrometry method. The obtained results were surprising if we consider several hair analyses previously published and based on a theory of the presence of xenobiotic in the only segment that comprised its intake. Among the two intoxication cases, we noticed the presence of CBF and OHCBF in hair segments corresponding to 45 days before, and more than 100 days after, the day of intoxication. Additionally, repeated hair samplings and subsequent analysis revealed a decrease of the carbofuran's concentration during the hair life.

journal_name

Forensic Sci Int

authors

Dulaurent S,Gaulier JM,Zouaoui K,Moesch C,François B,Lachâtre G

doi

10.1016/j.forsciint.2011.05.011

subject

Has Abstract

pub_date

2011-10-10 00:00:00

pages

e10-4

issue

1-3

eissn

0379-0738

issn

1872-6283

pii

S0379-0738(11)00226-X

journal_volume

212

pub_type

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