Abstract:
:Disorganized sleep patterns, can be found both during normal development and in pathological conditions. Aging could also be accompanied by a disorganization of the night sleep episode; sleep could be interrupted by spontaneous awakening, sleep cycle could be shortened or incomplete, sleep states modified. These patterns suggest an inability to sustain a stable condition, i.e. a condition of functional uncertainty. Biological and cognitive implications of functional uncertainty conditions are discussed. In particular, the hypothesis has been put forward that disturbances of sleep could have a detrimental role on memory. Recent results obtained in our lab support this hypothesis: recall is correlated with NREM-REM cycles proportion. Future research should ascertain the role of the functional uncertainty with respect to the kind of memory being involved during sleep, and establish how much and for which cognitive processes (including those involved in dream production) the inability to sustain a steady condition impairs the functioning during sleep. The duration of the functional uncertainty condition is also important. The long-term study of the link between functional uncertainty and cognitive resources, could be important for the understanding of the night life and for an adequate treatment of patients.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Salzarulo P,Formicola G,Lombardo P,Gori S,Rossi L,Murri L,Cipolli Csubject
Has Abstractpub_date
1997-06-01 00:00:00pages
118-22issue
2eissn
0300-9009issn
2240-2993journal_volume
97pub_type
杂志文章,评审abstract::Several genome-wide association studies have already explored the associations between rs498872 polymorphism and glioma, but the results of these studies were not consistent. Consequently, we conducted a meta-analysis of relevant studies to better analyze the effects of rs498872 polymorphism on individual susceptibili...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,meta分析
doi:10.1007/s13760-019-01081-y
更新日期:2019-06-01 00:00:00
abstract::Evidence suggests that symptoms of migraine are related to the involvement of the autonomic nervous system. Data on atrial conduction system are limited in migraineurs. We aimed to assess atrial electromechanical delay using tissue Doppler imaging (TDI) in patients with migraine. Forty-five migraine patients and age- ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-013-0273-8
更新日期:2014-12-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a chronic disease, the etiology of which has yet to be clarified, which causes activation of proinflammatory pathways that bring about joint and systemic inflammation. Although peripheral nervous system anomalies are observed widely in RA, very few case reports on changes in the central ne...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0879-3
更新日期:2020-02-01 00:00:00
abstract::Previous studies of multiple sclerosis (MS) patients have reported an inverse correlation between disability, the number of relapses and vitamin D levels in mostly white patients. It is unclear if this relationship has the same behavior in individuals with Hispanic backgrounds. To determine the relationship between vi...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-017-0834-3
更新日期:2018-03-01 00:00:00
abstract::The case of a 57-year-old woman is described with a two months history of proximal muscle weakness and pain, marked hypotrophy and brisk reflexes. Clinical investigation demonstrated normal serum CK, myopathic EMG and osteomalacia. Muscle biopsy showed type II fibre atrophy and mitochondrial alterations without inclus...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
abstract::A 54-year-old female patient presented acute hallucinatory psychotic episodes with irritative EEG for seven years before an initial state of complex partial mal. A single convulsive episode occurred 14 years after the beginning of the psychiatric symptoms. The intercritical EEG showed independent temporal lobe foci pr...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Epilepsy affects 50 million patients and their caregivers worldwide. Devices that facilitate the detection of seizures can have a large influence on a patient's quality of life, therapeutic decisions and the conduct of clinical trials with anti-epileptic drugs. This article provides an up-to-date overview and comparis...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-020-01417-z
更新日期:2020-12-01 00:00:00
abstract::Similar alterations in the neuronal cytoskeleton (paired helical filaments) and modifications in the molecular forms of acetylcholinesterase (specific decrease in the G4 form) have been detected in the elderly rat as well as in patients suffering from SDAT. These observations challenge the specificity of some manifest...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00
abstract::n-Hexane gives cause to one of the most common toxic polyneuropathies seen in poorly ventilated factories. It is a sensory-motor polyneuropathy ending up with axonal degeneration. Nerve biopsy reveals paranodal axonal swelling and secondary myelin retraction in early stages. Myelin retraction imitates demyelination ca...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01137-z
更新日期:2019-04-13 00:00:00
abstract::The objective of this study was to evaluate the tolerability and efficacy of lacosamide (LCM) in residential patients at our epilepsy centre. We assessed retrospectively 80 patients (mean age 36.2 years, range 18-63 years; 29 female) with intellectual disability (ID) and drug-resistant epilepsy using an industry-indep...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01098-3
更新日期:2019-09-01 00:00:00
abstract::Myasthenia gravis (MG) is one of the curable neurologic disorders. Various pharmacological therapies are administered for these patients and a thymectomy plays an important role in the therapy of myasthenia gravis, which develops a permanent or relative remission. We investigated the efficacy of intravenous immunoglob...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13760-016-0689-z
更新日期:2017-03-01 00:00:00
abstract::Diets that have effects on health problems can vary in their composition. Whilst following a regular diet (RD) a person typically consumes about 30% of calories from fat. Ketogenic diet (KD) is a form of diet whereby a person consumes as much as 90% of calories from fat. KD has been trialed as a treatment for neurolog...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01486-0
更新日期:2020-09-06 00:00:00
abstract::Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common heritable cause of stroke and vascular dementia in adults. We present a family from Serbia presenting with stroke and depression in the lack of vascular risk factors, with brain MRI indicating CADASI...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0174-2
更新日期:2013-09-01 00:00:00
abstract::The authors present and illustrate most of the ultrastructural abnormalities encountered in skeletal muscle in cases of neuromuscular disease. The diagnostic significance of the changes are discussed but emphasis is laid on the nonspecific character of most of them. For diagnostic purposes, examination by light micros...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1981-03-01 00:00:00
abstract::A correlation is made between the index of circulatory resistance given by ultrasonic flow-measurement and rheography. Patients with normal and increased blood pressure were studied. The characteristics of the transient and of the permanent ischaemic attacks are defined. ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Recently, great advances have been made in the surgical treatment of intramedullary spinal cord tumors (IMSCTs). Many articles have been published; but looking at the literature of the last 5 years, there are only descriptive reviews and no works in which a literature statistical analysis was performed. Here, we analy...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-016-0684-4
更新日期:2017-03-01 00:00:00
abstract::Down syndrome (DS) is a genetic disorder associated with mental and motor developmental delays in childhood. The aim of this study was to investigate the relationship of the femoral cartilage thickness with motor performance in children with Down syndrome (DS). A total of 39 children with DS in the age range of 12-42 ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01105-7
更新日期:2019-03-06 00:00:00
abstract::Despite the huge health and economic burden of migraine headache, few medications have been approved for its prophylactic treatment, most of which can potentially induce serious adverse effects. Coenzyme Q10 (CoQ10) is a supplement and has shown preliminary benefits in migraine prophylaxis. We aimed to assess this eff...
journal_title:Acta neurologica Belgica
pub_type: 临床试验,杂志文章
doi:10.1007/s13760-016-0697-z
更新日期:2017-03-01 00:00:00
abstract::Cerebral venous sinus thrombosis is an uncommon cause of stroke, which is more prevalent in Iran and the Middle East. We aimed to assess the etiology, radiologic, and clinical manifestations of cerebral venous sinus thrombosis, specifically the predictors of patients' outcome in Namazi hospital, Shiraz, Iran. In this ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-1009-6
更新日期:2020-08-01 00:00:00
abstract::The first applications of positron emission tomography (PET) for the study of brain tumours appeared early in the development of this technology. New trends in these particular PET applications tend to take into account the histological heterogeneity of these tumours and the necessity to integrate PET data in their su...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1997-09-01 00:00:00
abstract::A 68 year-old man developed progressive hemidystonia and chorea 8 months after a contralateral thalamic stroke. The neurological examination also showed a right pyramidal syndrome without hemiparesis, a right horizontal sectoranopia, and a right hemihypesthesia for all sensory modalities. The MRI revealed infarctions ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::We reviewed the clinical, neuropsychiatric, and EEG status of 53 turner syndrome (TS) females, aged 3-16 years, in Assiut university hospitals, Upper Egypt. The diagnosis and care of patients with TS in Egypt is still in the developing stage. Hence this study was undertaken to review the details of patients with TS wi...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-013-0264-9
更新日期:2014-03-01 00:00:00
abstract::Oculomotor functions are analysed by clinical examination and oculography in 21 cases of deep cerebral hematoma. Significant paralysis of verticality and of movements contralateral to the lesions was observed in all cases where the hemorrhage affected the paramedian thalamo-subthalamic region. A slight deficit of elev...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1983-11-01 00:00:00
abstract::Most of the brominated monoureide and bromide salt containing drugs are obtainable in Belgium without prescription. Apart from the regularly encountered suicidal attempts, these drugs can also, without the intention of the patient, cause bromism . We report two cases of patients recently admitted because of bromism af...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1984-03-01 00:00:00
abstract::Cisplatin is an anticancer agent widely used in the treatment of malignant tumors. One of the major adverse effects of cisplatin is its neurotoxicity. Memantine, an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has been reported to have neuroprotective effects against neurological deficits. This study...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01161-z
更新日期:2020-02-01 00:00:00
abstract::Multiple sclerosis (MS) is a neuro-immunological demyelinating disease. From the immunological aspects, it is well accepted that T cells play a pivotal role in the etiology of the disease. T helper (Th) 1 and Th17 cells are thought to be the main pathogenic T cells in the pathogenesis of MS and are known as effector T...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,meta分析
doi:10.1007/s13760-018-1028-3
更新日期:2019-03-01 00:00:00
abstract::Evaluation of the analgesic effect after a single application of the capsaicin 8 % cutaneous patch (Qutenza™) in 37 patients suffering from painful, distal symmetric polyneuropathy (PNP) for an average of 5 years. Patients ranged from 40 to 78 years of age and 22 subjects were HIV-positive. Patients were observed 4 we...
journal_title:Acta neurologica Belgica
pub_type: 临床试验,杂志文章
doi:10.1007/s13760-014-0395-7
更新日期:2015-09-01 00:00:00
abstract::Eight cases of acute or subacute hypercalcemic encephalopathy are described. The symptoms comprise digestive disorders, signs of dehydration and neuropsychological anomalies. Among the latter, it is stressed that impairments of upright stance and locomotion are present in all cases. The clinical picture is not charact...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract::Clinical records and EEGs of 114 consecutive patients with clinical diagnosis of Alzheimer's disease have been reviewed. The EEGs of 15 patients (13%) contained triphasic waves. Triphasic waves were always atypical as they occurred singularly or in short bursts, and/or they had occipital predominance, and/or they were...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Electrophysiological tests (visual and somatosensory evoked potentials, flicker fusion test) and electrophoretic examination of cerebrospinal fluid were performed in 17 patients who previously suffered from one or more attacks of optic neuritis. The association of the tests revealed the demyelinating inflammatory path...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1983-03-01 00:00:00