Abstract:
:Similar alterations in the neuronal cytoskeleton (paired helical filaments) and modifications in the molecular forms of acetylcholinesterase (specific decrease in the G4 form) have been detected in the elderly rat as well as in patients suffering from SDAT. These observations challenge the specificity of some manifestations of dementia to the human species and provide new opportunities to study these alterations using rat peripheral nervous system as an experimental model.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Klosen P,Goemaere-Vanneste J,Terao E,Van den Bosch de Aguilar Psubject
Has Abstractpub_date
1989-05-01 00:00:00pages
294-9issue
3-4eissn
0300-9009issn
2240-2993journal_volume
89pub_type
杂志文章abstract:BACKGROUND:Increased intima-media thickness (IMT) of the common carotid arteries (CCA) and elevated levels of highly sensitive C-reactive protein (hsCRP) are both shown to be associated with the occurrence of stroke. We investigated whether elevated hsCRP level is a risk factor for the increased IMT of the CCA independ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract::CADASIL is an autosomal dominant inherited arteriopathy caused by a point mutation in the Notch3 gene. Classically, it is characterised by recurrent ischemic strokes, often resulting in mental decline. Intracerebral haemorrhages in CADASIL have rarely been reported. We describe a young male with a genetically proven C...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract::Progressive supranuclear palsy (PSP) is a severe neurodegenerative disease still lacking of alleviating treatments for either cognitive or motor disturbances. Aimed at widening the spectrum of therapeutic options, here, we describe efficacy and safety of a long-term treatment with Rotigotine, a non-ergolinic dopamine ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0993-x
更新日期:2019-03-01 00:00:00
abstract::Electrophysiological tests (visual and somatosensory evoked potentials, flicker fusion test) and electrophoretic examination of cerebrospinal fluid were performed in 17 patients who previously suffered from one or more attacks of optic neuritis. The association of the tests revealed the demyelinating inflammatory path...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1983-03-01 00:00:00
abstract::We wanted to explore possible differences in disease presentation, frequency, and age of onset of dementia with Lewy bodies (DLB) between first-generation immigrants (FGI) and patients born in Belgium (PBIB). We conducted a retrospective study on all patients of our Memory Clinic between June 1, 2010 and January 31, 2...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01492-2
更新日期:2020-09-15 00:00:00
abstract::Headache is one of the chronic disorders that can trigger sexual dysfunction due to complex mechanisms. This study recruited 120 consecutive patients from our outpatient clinics with migraine (n = 60), TTH (n = 60) as well as healthy age-matched controls (n = 60) for a total of 180 patients. All the participants were ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01504-1
更新日期:2020-09-25 00:00:00
abstract::Between 1973 and 1978 spontaneous lysis of obstructions in an external cerebral artery was detected in seven out of 3500 patients who suffered from symptoms of cerebrovascular failure in the territory of the internal carotid or vertebral artery. All patients underwent our routine cerebrovascular Doppler ultrasound exa...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic process that typically occurs in the setting of immune dysregulation. In contrast to the characteristic pattern involving parieto-occipital and posterior frontal regions, predominant involvement of the infratentorial brain occurs in a minority of PRES...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-015-0431-2
更新日期:2015-12-01 00:00:00
abstract::Estradiol (E2) has been used in the treatment of Alzheimer's disease (AD) for many years but with various responses. Evidence from clinical studies, randomized clinical trials (RCTs), and observational studies further underscores the importance of E2 in postmenopause women diagnosed with AD. The purpose of this articl...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:10.1007/s13760-015-0593-y
更新日期:2016-09-01 00:00:00
abstract::Stroke is still a major cause of morbidity and mortality throughout the world, although better stratification and treatment modalities are being developed. As compared to ischemic stroke, intracerebral hemorrhage (ICH) possesses many unknown data and lacks guidelines for better prophylaxis. In this study, we aimed to ...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-013-0222-6
更新日期:2013-12-01 00:00:00
abstract::The most common causes of chronic cough in nonsmokers are postnasal drip syndrome, asthma, and gastroesophageal reflux disease. Drugs are also important in the etiology of resistant cough. Most common drugs inducing cough are the ACE inhibitors. Many drugs other than ACE inhibitors can also cause dry cough and one amo...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-012-0016-2
更新日期:2012-06-01 00:00:00
abstract::The authors distinguish between two evolutive forms of dementia, one being chracterized by prpgressive deterioration (for instance in the course of arteriopathic, degenerative or infections processes) and the other in which dementia sets in after the clinical picture has improved (for instance after meningeal haemorrh...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::Five to 10 mul of 196 cerebrospinal fluid samples were subjected to agar gel electrophoresis without previous concentration. No "degenerative" pattern was found to be correlated with any clinical diagnosis or group of diagnoses, Repeated freezing and thawing appears to have different effects on the different fractions...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1974-11-01 00:00:00
abstract::The association of carotid atherosclerosis with silent brain infarcts (SBIs) and white matter lesions (WMLs) currently remains unknown. This study aims to compare SBIs, deep white matter lesions (DWMLs), and periventricular white matter lesions (PWMLs) in ipsilateral and contralateral hemispheres to internal carotid a...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01517-w
更新日期:2020-10-09 00:00:00
abstract::Cluster headache (CH) is among the most painful headache disorders. There is still no unifying pathophysiological hypothesis to explain the trigeminal distribution, the circadian periodicity and the autonomic symptoms of the syndrome. We report the case of a patient with worsening of CH following administration of pra...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract::Spontaneous but incomplete remyelination is observed after a demyelinating lesion. We know since ten years now that oligodendrocyte progenitors, (OP) and totipotent neural stem cells remain present in the central nervous system of adult mammals. Moreover, these OP are more likely the cellular source of remyelinating c...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1999-03-01 00:00:00
abstract::Diffuse multicentric sarcomas of the brain, also called cerebral malignant lymphomas, sometimes present symmetrical topography. This is well demonstrated by a CAT mirror image obtained by the authors in the reported case. The diagnostic value of the image is underlined in view of the possible forms of therapy, in part...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::We report the case of a 44-year-old woman with chronic facial pain. She was treated with several analgesics, prophylactic medications and infiltrations, but all treatment modalities were ineffective. Finally, the diagnosis of medication-overuse headache complicating migraine without aura was made and an appropriate tr...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract:: ...
journal_title:Acta neurologica Belgica
pub_type: 信件
doi:10.1007/s13760-018-0951-7
更新日期:2018-12-01 00:00:00
abstract::Multiphase CT angiography (CTA) in collateral assessment provides time-resolved cerebral angiograms of the intracranial vasculature, requiring a high-speed multidetector CT (MDCT) scanner with ≥ 64 slices. Unfortunately, many hospitals are equipped with lower speed MDCT scanners. Herein, we present our experience perf...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-1019-4
更新日期:2019-06-01 00:00:00
abstract::Although cerebral palsy (CP), which affects the quality of life of many children and their families, is the most common cause of motor dysfunction in children, no comprehensive bibliometric study has holistically evaluated the publications on CP. This study aimed to analyze the scientific outputs published on CP in pe...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-020-01549-2
更新日期:2020-11-23 00:00:00
abstract::We report a 44-year-old female patient without any familial history of dementia presenting with increasing disturbances in behaviour and language followed by a progressive cognitive deterioration. Neuropsychological evaluation revealed a significant impairment on frontal lobe tests. A brain PET scan disclosed a severe...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract::Data examining the association between vitamin D and diabetic peripheral neuropathy are limited. This study investigated the serum levels of vitamin D, vitamin D-binding protein (VDBP), and vitamin D receptor (VDR) in diabetics in the Yozgat region of Turkey, and assessed their relationships with diabetic peripheral n...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-014-0304-0
更新日期:2015-03-01 00:00:00
abstract::The case of a 57-year-old woman is described with a two months history of proximal muscle weakness and pain, marked hypotrophy and brisk reflexes. Clinical investigation demonstrated normal serum CK, myopathic EMG and osteomalacia. Muscle biopsy showed type II fibre atrophy and mitochondrial alterations without inclus...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
abstract::Multiple sclerosis (MS) often starts in the form of clinically isolated syndrome (CIS) and only some of the CIS patients progress to relapsing-remitting MS (RRMS). Biomarkers to predict conversion from CIS to MS are thus greatly needed for making correct treatment decisions. To identify a predictive cerebrospinal flui...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-018-0954-4
更新日期:2019-03-01 00:00:00
abstract::123Iodo-Amphetamine (IAMP) brain distribution was studied with a specially dedicated multilevel tomographic system in 30 patients with vascular ischemic (18) or hemorrhagic (12) disorders. Results were compared with clinical data, CT scan and rCBF measurement obtained by the 133Xe continuous inhalation method. Abnorma...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract:: ...
journal_title:Acta neurologica Belgica
pub_type: 新闻
doi:10.1007/s13760-019-01097-4
更新日期:2019-03-01 00:00:00
abstract::Myasthenia gravis (MG) is one of the curable neurologic disorders. Various pharmacological therapies are administered for these patients and a thymectomy plays an important role in the therapy of myasthenia gravis, which develops a permanent or relative remission. We investigated the efficacy of intravenous immunoglob...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13760-016-0689-z
更新日期:2017-03-01 00:00:00
abstract::Despite intensive research efforts, the cause of the muscular dystrophies has remained elusive for many decades. In the late 1980s, major advances in molecular genetics have led to the discovery of the dystrophin gene and its protein product, dystrophin. Mutations in the dystrophin gene result in dystrophin deficiency...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::Functional brain imaging studies, such as positron emission tomography and functional nuclear magnetic resonance imaging, are based on the regional increases in cerebral blood flow, glucose consumption and oxygen consumption that are associated with regional increases in neuronal activity. The cellular basis of the si...
journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2002-12-01 00:00:00