当前位置： SCI文献检索 > DRUG AND ALCOHOL DEPENDENCE期刊下所有文献 > Inhibition of epinephrine-induced myocardial necrosis in rats by administration of single doses of ethanol.

Inhibition of epinephrine-induced myocardial necrosis in rats by administration of single doses of ethanol.

Abstract：

:The oral administration of single doses (0.5-6.0 g/kg) of ethanol to rats, shortly before injecting them with a large dose (3.0 mg base/kg) of epinephrine subcutaneously, significantly reduced the severity of the myocardial damage produced by the epinephrine. The larger the dose of ethanol, the greater was the protective effect. The results were the same, regardless of the method used to determine the degree of cardiac injury. Experiments employing various agents to determine the mechanisms of ethanol action have tentatively suggested that a platelet de-aggregating or an osmotic effect of alcohol may be involved.

journal_name

Drug Alcohol Depend

journal_title

Drug and alcohol dependence

authors

Mallov S,Gilmour RF

doi

10.1016/0376-8716(77)90041-2

subject

Has Abstract

pub_date

1977-09-01 00:00:00

pages

397-407

issue

5-6

eissn

0376-8716

issn

1879-0046

pii

0376-8716(77)90041-2

journal_volume

2

pub_type

杂志文章

相关文献

DRUG AND ALCOHOL DEPENDENCE文献大全
  • Age trends in alcohol use behavior patterns among U.S. adults ages 18-65.

    abstract：INTRODUCTION:Although much of the work on risky alcohol use behaviors, such as heavy drinking, focuses on adolescence and young adulthood, these behaviors are associated with negative health consequences across all ages. Existing studies on age trends have focused on a single alcohol use behavior across many ages, usin...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2019.107689

    authors： Bray BC,Dziak JJ,Lanza ST

    更新日期：2019-12-01 00:00:00

  • Increased QT interval variability index in acute alcohol withdrawal.

    abstract：OBJECTIVE:Acute alcohol withdrawal is associated with increased cardiovascular mortality, most likely due to cardiac arrhythmias. As the QT interval reflects the most critical phase for the generation of reentry and thus for arrhythmia, we examined QT variability in patients suffering from acute alcohol withdrawal. ME...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2007.01.010

    authors： Bär KJ,Boettger MK,Koschke M,Boettger S,Grotelüschen M,Voss A,Yeragani VK

    更新日期：2007-07-10 00:00:00

  • Social network correlates of self-reported non-fatal overdose.

    abstract：:The leading cause of death among heroin users is drug overdose. The present study examined the relationship between history of self-reported drug overdoses and social network characteristics among cocaine and opiate users. Data were from cross-sectional surveys administered from March 2001 through February 2003 as par...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2003.09.005

    authors： Latkin CA,Hua W,Tobin K

    更新日期：2004-01-07 00:00:00

  • The effect of Naftidrofuryl on ethanol-induced liver damage in chronic alcoholic patients.

    abstract：:A prospective double-blind placebo-controlled trial of intramuscular Naftidrofuryl was carried out on 32 randomly selected hospitalized male alcoholic patients with clinical, biochemical and histological evidence of hepatic damage. Seventeen patients received the drug (40 mg in 5 ml i.m. three times daily for 6 days) ...

    journal_title：Drug and alcohol dependence

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0376-8716(82)90004-7

    authors： Majumdar SK,Shaw GK,O'Gorman P,Thomson AD

    更新日期：1982-10-01 00:00:00

  • Xorphanol.

    abstract：:Xorphanol is a new mixed agonist-antagonist from the morphinan class of analgesics. On the basis of animal experiments, the physical dependence liability of xorphanol is predicted to be of a low order in man. Conceptually, xorphanol is of interest since in vitro experiments have revealed anti-naloxone properties and r...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/0376-8716(85)90068-7

    authors： Howes JF,Villarreal JE,Harris LS,Essigmann EM,Cowan A

    更新日期：1985-02-01 00:00:00

  • Major depression and treatment response in adolescents with ADHD and substance use disorder.

    abstract：BACKGROUND:Major depressive disorder (MDD) frequently co-occurs in adolescents with substance use disorders (SUDs) and attention deficit hyperactivity disorder (ADHD), but the impact of MDD on substance treatment and ADHD outcomes and implications for clinical practice are unclear. METHODS:Adolescents (n=303; ages 13-...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.drugalcdep.2011.08.001

    authors： Warden D,Riggs PD,Min SJ,Mikulich-Gilbertson SK,Tamm L,Trello-Rishel K,Winhusen T

    更新日期：2012-01-01 00:00:00

  • Medical outcomes associated with prescription opioid abuse via oral and non-oral routes of administration.

    abstract：BACKGROUND:Prescription opioid abuse and misuse is a serious and growing public health issue. While the most common form of abuse is swallowing intact tablets/capsules, some abusers manipulate, or tamper with, these medications by altering the dosage form to allow for non-oral routes of administration (e.g., injection,...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2017.01.039

    authors： Green JL,Bucher Bartelson B,Le Lait MC,Roland CL,Masters ET,Mardekian J,Bailey JE,Dart RC

    更新日期：2017-06-01 00:00:00

  • Distribution of deaths by unintentional illicit drug overdose in Italy based on periodicity over time, 1984-2000.

    abstract：AIM:To assess whether substance-abusing people have a higher risk of dying from unintentional acute intoxication in specific periods of the year. METHODS:A total of 15,792 deaths (males=14,259; females=1533) were ascertained to be due to unintentional acute intoxication by illicit drugs in Italy in the study period (1...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/s0376-8716(03)00186-8

    authors： Rocchi MB,Miotto P,Preti A

    更新日期：2003-10-24 00:00:00

  • Gender-based differences in injecting drug use by young adults who experienced maltreatment in childhood: Findings from an Australian birth cohort study.

    abstract：BACKGROUND:Childhood maltreatment has been associated with a range of adverse mental and psychosocial outcomes, but its association with subsequent injecting drug use (IDU) is less clear. This study investigates the associations between specific and multiple forms of substantiated childhood maltreatment and IDU reporte...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2016.12.027

    authors： Abajobir AA,Kisely S,Williams G,Clavarino A,Strathearn L,Najman JM

    更新日期：2017-04-01 00:00:00

  • Gender and nonmedical prescription opioid use and DSM-5 nonmedical prescription opioid use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions - III.

    abstract：BACKGROUND:Little is known about sex-specific risk for nonmedical prescription opioid use (NMPOU) and DSM-5 nonmedical prescription opioid use disorder (NMPOUD). The objective of the present study was to present prevalence, correlates, psychiatric comorbidity, treatment and disability of NMPOU and DSM-5 NMPOUD among me...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2015.08.026

    authors： Kerridge BT,Saha TD,Chou SP,Zhang H,Jung J,Ruan WJ,Smith SM,Huang B,Hasin DS

    更新日期：2015-11-01 00:00:00

  • Problem drinking is associated with increased prevalence of sexual risk behaviors among men who have sex with men (MSM) in Lima, Peru.

    abstract：BACKGROUND:Alcohol use is an important but understudied HIV risk factor among men who have sex with men (MSM), particularly in Latin America. We studied the relationship between problem drinking and sexual risk among MSM in Lima, Peru. METHODS:We recruited 718 participants from 24 neighborhoods for a study on sexually...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2013.01.011

    authors： Deiss RG,Clark JL,Konda KA,Leon SR,Klausner JD,Caceres CF,Coates TJ

    更新日期：2013-09-01 00:00:00

  • A randomized trial of contingency management for adolescent marijuana abuse and dependence.

    abstract：:An initial efficacy test of an innovative behavioral outpatient treatment model for adolescents with problematic use of marijuana enrolled 69 adolescents, aged 14-18, and randomly assigned them to one of two treatment conditions. Both conditions received individualized Motivational Enhancement and Cognitive Behavioral...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.drugalcdep.2009.07.009

    authors： Stanger C,Budney AJ,Kamon JL,Thostensen J

    更新日期：2009-12-01 00:00:00

  • Gender moderates the association between distress tolerance and alcohol use among individuals with opioid use disorder.

    abstract：BACKGROUND:Alcohol use among individuals with opioid use disorder (OUD) can be dangerous, and understanding factors contributing to alcohol use in this population is important. The current study examined alcohol use among individuals with prescription OUD based on distress tolerance. It was hypothesized that individual...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2018.05.016

    authors： Gilmore AK,Jones JL,Moreland AD,Hahn CK,Brady KT,Back SE

    更新日期：2018-09-01 00:00:00

  • Self-administration of cocaine-pentobarbital mixtures by rhesus monkeys.

    abstract：:A number of experiments have evaluated self-administration of the combination of a stimulant and an opioid. Less is known about the combination of a stimulant and a CNS depressant. The present experiment was designed to examine self-administration of the mixture of cocaine and pentobarbital (PB). Rhesus monkeys (n=4) ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2008.10.013

    authors： Woolverton WL,Wang Z

    更新日期：2009-03-01 00:00:00

  • Effects of chronic cocaine use on physical health: a prospective study in a general population sample.

    abstract：:Few studies have examined long-term effects of chronic cocaine use on physical health in the general population. The current study assesses the effects of chronic cocaine use by the late twenties on physical health by the mid thirties in a longitudinal cohort from the general population. Measures of physical health in...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/s0376-8716(96)01285-9

    authors： Chen K,Scheier LM,Kandel DB

    更新日期：1996-12-02 00:00:00

  • U.S. trends in the supply of providers with a waiver to prescribe buprenorphine for opioid use disorder in 2016 and 2018.

    abstract：BACKGROUND:Healthcare providers can receive waivers to prescribe buprenorphine for opioid use disorder, an evidence-based medication. The United States federal government has undertaken numerous recent efforts to expand access to waivers. This study describes national trends in the U.S. in 2016 and 2018, geospatial cha...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2019.06.029

    authors： Ghertner R

    更新日期：2019-11-01 00:00:00

  • Blood levels do not predict behavioral or physiological effects of Δ⁹-tetrahydrocannabinol in rhesus monkeys with different patterns of exposure.

    abstract：BACKGROUND:Recent changes in the legality of cannabis have prompted evaluation of whether blood levels of Δ(9)-tetrahydrocannabinol (THC) or its metabolites could be used to substantiate impairment, particularly related to behavioral tasks such as driving. However, because marked tolerance develops to behavioral effect...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2014.02.696

    authors： Ginsburg BC,Hruba L,Zaki A,Javors MA,McMahon LR

    更新日期：2014-06-01 00:00:00

  • Human spinal fluid methadone levels.

    abstract：:Cerebral spinal fluid (CSF) levels of methadone were measured in nine methadone maintenance patients requiring lumbar punctures for medical or surgical treatment. Concurrent serum methadone levels were also determined. The CSF concentration of methadone in all cases was a fraction of the corresponding serum level--ran...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/0376-8716(78)90022-4

    authors： Rubenstein RB,Kreek MJ,Mbawa N,Wolff WI,Korn R,Gutjahr CL

    更新日期：1978-03-01 00:00:00

  • Gabapentin maintenance decreases smoked cocaine-related subjective effects, but not self-administration by humans.

    abstract：:Data from research with laboratory animals indicate that cocaine self-administration can be reduced by lambda-aminobutyric acid (GABA) agonists. Yet, the effectiveness of GABA agonists to decrease human cocaine self-administration has not been investigated under controlled laboratory conditions. The purpose of this st...

    journal_title：Drug and alcohol dependence

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.drugalcdep.2003.10.015

    authors： Hart CL,Ward AS,Collins ED,Haney M,Foltin RW

    更新日期：2004-03-08 00:00:00

  • Child maltreatment increases sensitivity to adverse social contexts: neighborhood physical disorder and incident binge drinking in Detroit.

    abstract：INTRODUCTION:Exposure to child maltreatment is associated with elevated risk for behavioral disorders in adulthood. One explanation for this life-course association is that child maltreatment increases vulnerability to the effects of subsequent stressors; however, the extent to which maltreatment increases sensitivity ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2011.09.013

    authors： Keyes KM,McLaughlin KA,Koenen KC,Goldmann E,Uddin M,Galea S

    更新日期：2012-04-01 00:00:00

  • Initiation into methamphetamine use for young gay and bisexual men.

    abstract：:Research over the past 10 years has suggested that methamphetamine use has become a significant problem and is associated with risky sexual behaviors among gay and bisexual men. In order to better understand initiation into methamphetamine use among gay and bisexual men, qualitative analyses were performed on a sample...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2007.02.017

    authors： Parsons JT,Kelly BC,Weiser JD

    更新日期：2007-10-08 00:00:00

  • Separate and combined effects of the cannabinoid agonists nabilone and Δ⁹-THC in humans discriminating Δ⁹-THC.

    abstract：BACKGROUND:Agonist replacement treatment is a promising strategy to manage cannabis-use disorders. The aim of this study was to assess the combined effects of the synthetic cannabinoid agonist nabilone and Δ⁹-tetrahydrocannabinol (Δ⁹-THC) using drug-discrimination procedures, which are sensitive to drug interactions. T...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.drugalcdep.2010.11.019

    authors： Lile JA,Kelly TH,Hays LR

    更新日期：2011-07-01 00:00:00

  • Association between buprenorphine/naloxone and high-dose opioid analgesic prescribing in Kentucky, 2012-2017.

    abstract：INTRODUCTION:Buprenorphine/naloxone treatment is a highly effective treatment for opioid use disorder decreasing illicit opioid use and both all-cause and opioid-involved overdose mortality. The purpose of this study was to investigate the relationships between buprenorphine/naloxone prescribing and high-dose opioid an...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2019.107606

    authors： Luu H,Slavova S,Freeman PR,Lofwall M,Browning S,Slade E,Bush H

    更新日期：2019-12-01 00:00:00

  • Differential expression and functional role of cannabinoid genes in alcohol users.

    abstract：BACKGROUND:Genetic factors account for about fifty percent of the risk for alcoholism and alcohol dependence (AD) has been reported to be influenced by cannabinoid receptors (CBRs) and the endocannabinoid system (ECS). Previous studies have focused on cannabinoids and alcohol-related effects in the CNS; however, the ro...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2013.08.023

    authors： Agudelo M,Yndart A,Morrison M,Figueroa G,Muñoz K,Samikkannu T,Nair MP

    更新日期：2013-12-01 00:00:00

  • Measuring pain medication expectancies in adults treated for substance use disorders.

    abstract：BACKGROUND:The U.S. prevalence of misuse of prescription opioid analgesics has increased substantially over the past decade but research on the factors influencing misuse of these medications remains preliminary. In the literature on alcohol, marijuana and stimulants, substance-related expectancies have been found to p...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2010.10.007

    authors： Ilgen MA,Roeder KM,Webster L,Mowbray OP,Perron BE,Chermack ST,Bohnert AS

    更新日期：2011-05-01 00:00:00

  • Trusting the source: The potential role of drug dealers in reducing drug-related harms via drug checking.

    abstract：OBJECTIVES:Drug checking technologies (DCTs) have been implemented as a response to the ongoing opioid overdose epidemic. We examined the level of trust people who use drugs (PWUD) have in their drug dealers as well as their perspectives on the potential for drug dealers to use DCTs to provide knowledge of drug content...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2019.01.035

    authors： Bardwell G,Boyd J,Arredondo J,McNeil R,Kerr T

    更新日期：2019-05-01 00:00:00

  • Spatial and temporal trends in alcohol consumption in Belgian cities: A wastewater-based approach.

    abstract：BACKGROUND:In recent years, scientific evidence has emerged that wastewater-based epidemiology can deliver complementary information concerning the use of different substances of abuse. In this study, the potential of wastewater-based epidemiology in monitoring spatial and temporal trends in alcohol consumption in diff...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2016.01.002

    authors： Boogaerts T,Covaci A,Kinyua J,Neels H,van Nuijs AL

    更新日期：2016-03-01 00:00:00

  • Genetic moderators and psychiatric mediators of the link between sexual abuse and alcohol dependence.

    abstract：BACKGROUND/OBJECTIVE:This study used a case-control female sample to test psychiatric mediators and genetic moderators of the effect of sexual abuse on later alcohol dependence. The study also tested differences between alcohol dependent women with or without a history of sexual abuse on variables that might affect tre...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2010.10.024

    authors： Copeland WE,Magnusson A,Göransson M,Heilig MA

    更新日期：2011-06-01 00:00:00

  • Utilization of communication technology by patients enrolled in substance abuse treatment.

    abstract：BACKGROUND:Technology-based applications represent a promising method for providing efficacious, widely available interventions to substance abuse treatment patients. However, limited access to communication technology (i.e., mobile phones, computers, internet, and e-mail) could significantly impact the feasibility of ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2012.10.003

    authors： McClure EA,Acquavita SP,Harding E,Stitzer ML

    更新日期：2013-04-01 00:00:00

  • Behavioral effects of cocaine alone and in combination with ethanol or marijuana in humans.

    abstract：:Intranasal cocaine (COC) and oral ethanol (ETOH) were administered to one group of seven research volunteers during daily experimental sessions. Following the determination of baseline subjective and performance measures, an ETOH cocktail (0, 19.4, 38.7 or 58.1 g of ETOH in lemonade) was consumed over a 10-min period....

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/0376-8716(93)80001-u

    authors： Foltin RW,Fischman MW,Pippen PA,Kelly TH

    更新日期：1993-04-01 00:00:00