Abstract：
BACKGROUND:Childhood maltreatment has been associated with a range of adverse mental and psychosocial outcomes, but its association with subsequent injecting drug use (IDU) is less clear. This study investigates the associations between specific and multiple forms of substantiated childhood maltreatment and IDU reported at 21 years. METHOD:The Mater-University of Queensland Study of Pregnancy is a prospective birth cohort study. It recruited pregnant women at their first antenatal clinic visit and collected data on their children at 21 years. Data from 3750 participants (1769 males and 1981 females) were analysed using agency substantiated childhood maltreatment from birth to 14 years of age and self-reports of ever IDU at 21 years. We used multivariable logistic regression analyses to control for possible confounders. RESULTS:The sample's mean age was 20.6 years. Some 4.1% (n=72) of males and 4.6% (n=91) of females had experienced substantiated childhood maltreatment. The prevalence of IDU was 6.6% (n=118) and 4.6% (n=91) for males and females, respectively. In adjusted models, all forms of substantiated childhood maltreatment, with the exception of sexual abuse, were associated with IDU in females (adjusted odds ratios (AORs)=2.69-3.02) but only emotional abuse (AOR=2.51) was associated with IDU in males. Multiply occurring forms of childhood maltreatment were also associated with IDU in females (AORs=2.36-3.41) but not in males. CONCLUSIONS:Injecting drug use appears to be an adverse outcome of childhood maltreatment particularly in females. Additional research is needed to better understand why females appear to be more affected than males.
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
Abajobir AA,Kisely S,Williams G,Clavarino A,Strathearn L,Najman JMdoi
10.1016/j.drugalcdep.2016.12.027subject
Has Abstractpub_date
2017-04-01 00:00:00pages
163-169eissn
0376-8716issn
1879-0046pii
S0376-8716(17)30071-6journal_volume
173pub_type
杂志文章abstract：:In the search for clinical and biological variables that may predict relapse of alcohol dependent patients after detoxification, we followed up for 1 year male patients that had undergone successful detoxification. The patients had been tested earlier during their usual alcohol consumption and immediately after detoxi...
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journal_title：Drug and alcohol dependence
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journal_title：Drug and alcohol dependence
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journal_title：Drug and alcohol dependence
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更新日期：2017-10-01 00:00:00
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pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
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更新日期：2002-08-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
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更新日期：2009-01-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
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更新日期：1995-07-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1995-10-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.12.011
更新日期：2017-04-01 00:00:00
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更新日期：2018-07-01 00:00:00
