当前位置： SCI文献检索 > DRUG AND ALCOHOL DEPENDENCE期刊下所有文献 > Genetic moderators and psychiatric mediators of the link between sexual abuse and alcohol dependence.

Genetic moderators and psychiatric mediators of the link between sexual abuse and alcohol dependence.

Abstract：

BACKGROUND/OBJECTIVE:This study used a case-control female sample to test psychiatric mediators and genetic moderators of the effect of sexual abuse on later alcohol dependence. The study also tested differences between alcohol dependent women with or without a history of sexual abuse on variables that might affect treatment planning. METHODS:A case-control design compared 192 treatment-seeking alcohol dependent women with 177 healthy population controls. All participants were assessed for alcohol-related behaviors, sexual abuse history, psychiatric problems, and personality functioning. Markers were genotyped in the CRHR1, MAO-A and OPRM1 genes. RESULTS:The association of sexual abuse with alcohol dependence was limited to the most severe category of sexual abuse involving anal or vaginal penetration. Of the five psychiatric disorders tested, anxiety, anorexia nervosa, and bulimia met criteria as potential mediators of the abuse-alcohol dependence association. Severe sexual abuse continued to have an independent effect on alcohol dependence status even after accounting for these potential mediators. None of the candidate genetic markers moderated the association between sexual abuse and alcohol dependence. Of alcohol dependent participants, those with a history of severe abuse rated higher on alcoholism severity, and psychiatric comorbidities. CONCLUSION:Sexual abuse is associated with later alcohol problems directly as well as through its effect on psychiatric problems. Treatment-seeking alcohol dependent women with a history of abuse have distinct features as compared to other alcohol dependent women.

journal_name

Drug Alcohol Depend

journal_title

Drug and alcohol dependence

authors

Copeland WE,Magnusson A,Göransson M,Heilig MA

doi

10.1016/j.drugalcdep.2010.10.024

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

183-9

issue

3

eissn

0376-8716

issn

1879-0046

pii

S0376-8716(10)00400-X

journal_volume

115

pub_type

杂志文章

相关文献

DRUG AND ALCOHOL DEPENDENCE文献大全
  • Beyond the walls: Risk factors for overdose mortality following release from the Philadelphia Department of Prisons.

    abstract：BACKGROUND:High overdose mortality after release from state prison systems is well documented; however, little is known about overdose mortality following release from local criminal justice systems (CJS). The purpose of this study was to assess overdose mortality following release from a local CJS in Philadelphia, PA....

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2018.04.034

    authors： Pizzicato LN,Drake R,Domer-Shank R,Johnson CC,Viner KM

    更新日期：2018-08-01 00:00:00

  • Human spinal fluid methadone levels.

    abstract：:Cerebral spinal fluid (CSF) levels of methadone were measured in nine methadone maintenance patients requiring lumbar punctures for medical or surgical treatment. Concurrent serum methadone levels were also determined. The CSF concentration of methadone in all cases was a fraction of the corresponding serum level--ran...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/0376-8716(78)90022-4

    authors： Rubenstein RB,Kreek MJ,Mbawa N,Wolff WI,Korn R,Gutjahr CL

    更新日期：1978-03-01 00:00:00

  • Treatment of adolescent tobacco smokers: issues and opportunities for exposure reduction approaches.

    abstract：:The cycle of tobacco dependence typically begins with the initiation of tobacco use during adolescence. Many teenagers try to quit smoking, fail and subsequently desire treatment for their tobacco dependence. Adolescents do not currently benefit from the same level of societal support for quit attempts as adults, and ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,评审

    doi：10.1016/s0376-8716(03)00012-7

    authors： Moolchan ET,Aung AT,Henningfield JE

    更新日期：2003-06-05 00:00:00

  • Aspects of alcohol use disorder affecting social cognition as assessed using the Mini Social and Emotional Assessment (mini-SEA).

    abstract：BACKGROUND:Alcohol Use Disorder (AUD) is associated with problems with processing complex social scenarios. Little is known about the relationship between distinct AUD-related factors (e.g., years of problematic drinking), aspects of cognitive function and dysfunction in individuals diagnosed with AUD, and the relative...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2018.03.004

    authors： Cox S,Bertoux M,Turner JJD,Moss A,Locker K,Riggs K

    更新日期：2018-06-01 00:00:00

  • Co-use of alcohol, tobacco, and licit and illicit controlled substances among pregnant and non-pregnant women in the United States: Findings from 2006 to 2014 National Survey on Drug Use and Health (NSDUH) data.

    abstract：BACKGROUND:The use, misuse and co-use of alcohol, cannabis, tobacco, and other licit and illicit controlled substances has increased in past decades leading to higher rates of morbidity, overdose, and mortality in women of reproductive age. Co-use compounds the adverse health effects of substance use compared to single...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2019.107729

    authors： Qato DM,Zhang C,Gandhi AB,Simoni-Wastila L,Coleman-Cowger VH

    更新日期：2020-01-01 00:00:00

  • Public health strategies for prevention and control of HSV-2 in persons who use drugs in the United States.

    abstract：BACKGROUND:Herpes simplex virus type 2 (HSV-2) affects HIV acquisition, transmission, and disease progression. Effective medications for genital herpes and for HIV/AIDS exist. Parenteral transmission of HIV among persons who inject drugs is decreasing. Reducing sexual transmission of HIV and HSV-2 among persons who use...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,评审

    doi：10.1016/j.drugalcdep.2013.03.013

    authors： Semaan S,Leinhos M,Neumann MS

    更新日期：2013-08-01 00:00:00

  • Effects of 6-hydroxydopamine or 5,7-dihydroxy-tryptamine on the development of physical dependence on ethanol.

    abstract：:Infant rats, treated intracisternally with 6-hydroxydopamine or 5,7-dihydroxytryptamine, alone or in combination with desmethylimipramine or pargyline, at 5 to 7 days of age, had significant specific depletions of brain norepinephrine, dopamine, both of these amines, or serotonin at 2.5 months of age. Despite apparent...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/0376-8716(77)90037-0

    authors： Frye GD,Ellis FW

    更新日期：1977-09-01 00:00:00

  • Exercise training - A beneficial intervention in the treatment of alcohol use disorders?

    abstract：BACKGROUND:A growing body of evidence suggests that exercise training may have multiple beneficial effects in individuals with mental health or substance use disorders. Yet, relatively little knowledge exists regarding the benefits of exercise training to augment treatment for alcohol use disorders (AUDs). PURPOSE:The...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,评审

    doi：10.1016/j.drugalcdep.2015.11.019

    authors： Stoutenberg M,Rethorst CD,Lawson O,Read JP

    更新日期：2016-03-01 00:00:00

  • "Those edibles hit hard": Exploration of Twitter data on cannabis edibles in the U.S.

    abstract：AIMS:Several states in the U.S. have legalized cannabis for recreational or medical uses. In this context, cannabis edibles have drawn considerable attention after adverse effects were reported. This paper investigates Twitter users' perceptions concerning edibles and evaluates the association edibles-related tweeting ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2016.04.029

    authors： Lamy FR,Daniulaityte R,Sheth A,Nahhas RW,Martins SS,Boyer EW,Carlson RG

    更新日期：2016-07-01 00:00:00

  • Aggression and violence at ambulance attendances where alcohol, illicit and/or pharmaceutical drugs were recorded: A 5-year study of ambulance records in Victoria, Australia.

    abstract：BACKGROUND:This study describes the frequency and characteristics of aggression and/or violence in ambulance attendances involving alcohol, illicit and/or pharmaceutical drug use in Victoria, Australia between January 2012 and January 2017. METHODS:Patient characteristics, context, and substance use involvement in amb...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2019.107685

    authors： Coomber K,Curtis A,Vandenberg B,Miller PG,Heilbronn C,Matthews S,Smith K,Wilson J,Moayeri F,Mayshak R,Lubman DI,Scott D

    更新日期：2019-12-01 00:00:00

  • Predicting drinking onset with discrete-time survival analysis in offspring from the San Diego prospective study.

    abstract：:Previous research has shown that an early onset of drinking is associated with a range of problematic drinking outcomes in adulthood. However, earlier drinking is also linked to additional characteristics that themselves predict alcohol problems including male gender, a family history (FH) of alcoholism, age, race, pa...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2009.10.015

    authors： Trim RS,Schuckit MA,Smith TL

    更新日期：2010-03-01 00:00:00

  • The Alcohol Use Disorders Identification Test (AUDIT) as a screening instrument for adolescents.

    abstract：BACKGROUND:The Alcohol Use Disorders Identification Test (AUDIT) is an international screening instrument extensively employed in adult target groups. However, there is scarce information on screening with the AUDIT in adolescent populations. The purpose of this study was to determine the cut-off point for hazardous, h...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2009.01.017

    authors： Santis R,Garmendia ML,Acuña G,Alvarado ME,Arteaga O

    更新日期：2009-08-01 00:00:00

  • Nicotine concentration of e-cigarettes used by adolescents.

    abstract：OBJECTIVE:E-cigarettes are popular among youth, but little is known about the nicotine concentrations of e-liquids used by adolescents. MATERIALS AND METHOD:In Spring, 2014, we conducted cross-sectional surveys in four Connecticut high schools and two middle schools. Among past-30-day e-cigarette users (n=513, 45% fem...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2016.06.031

    authors： Morean ME,Kong G,Cavallo DA,Camenga DR,Krishnan-Sarin S

    更新日期：2016-10-01 00:00:00

  • Recreational marijuana legalization and prescription opioids received by Medicaid enrollees.

    abstract：OBJECTIVES:Medical marijuana use may substitute prescription opioid use, whereas nonmedical marijuana use may be a risk factor of prescription opioid misuse. This study examined the associations between recreational marijuana legalization and prescription opioids received by Medicaid enrollees. METHODS:State-level qua...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2018.09.016

    authors： Shi Y,Liang D,Bao Y,An R,Wallace MS,Grant I

    更新日期：2019-01-01 00:00:00

  • Cocaine use disorders and suicidal ideation.

    abstract：:The goal of this study was to determine the contribution of substance abuse to the expression of suicidal ideation in a sample of patients referred for evaluation of chemical dependency in a large urban Psychiatric Emergency Service (PES). Records from 777 consecutive patients referred to the chemical dependency servi...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/s0376-8716(02)00337-x

    authors： Garlow SJ,Purselle D,D'Orio B

    更新日期：2003-05-01 00:00:00

  • The two-faceted nature of impulsivity in patients with borderline personality disorder and substance use disorder.

    abstract：BACKGROUND:Impulsivity, which has been the subject of extensive debate in psychiatric research, is a clinically important concept, especially with respect to Borderline Personality Disorder (BPD) and Substance Use Disorders (SUD). The current study aims to examine the presence of two aspects of impulsivity (self-report...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2016.03.015

    authors： Maraz A,Andó B,Rigó P,Harmatta J,Takách G,Zalka Z,Boncz I,Lackó Z,Urbán R,van den Brink W,Demetrovics Z

    更新日期：2016-06-01 00:00:00

  • A simulative comparison of respondent driven sampling with incentivized snowball sampling--the "strudel effect".

    abstract：BACKGROUND:Respondent driven sampling (RDS) and incentivized snowball sampling (ISS) are two sampling methods that are commonly used to reach people who inject drugs (PWID). METHODS:We generated a set of simulated RDS samples on an actual sociometric ISS sample of PWID in Vilnius, Lithuania ("original sample") to asse...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2013.11.020

    authors： Gyarmathy VA,Johnston LG,Caplinskiene I,Caplinskas S,Latkin CA

    更新日期：2014-02-01 00:00:00

  • Screening for drug use disorders in the emergency department: performance of the rapid drug problems screen (RDPS).

    abstract：:Little research is available on brief screening instruments for identify those meeting diagnostic criteria for drug dependence or abuse. A brief, four-item screening instrument, called the rapid drug problems screen (RDPS), was developed from a similar instrument for alcohol use disorders, the rapid alcohol problems s...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2003.12.010

    authors： Cherpitel CJ,Borges G

    更新日期：2004-05-10 00:00:00

  • Cannabis use in adolescence and risk of future disability pension: a 39-year longitudinal cohort study.

    abstract：AIMS:This study aimed at examining a possible association between cannabis use in adolescence and future disability pension (DP). DP can be granted to any person in Sweden aged 16-65 years if working capacity is judged to be permanently reduced due to long-standing illness or injury. METHODS:Data were obtained from a ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2014.07.038

    authors： Danielsson AK,Agardh E,Hemmingsson T,Allebeck P,Falkstedt D

    更新日期：2014-10-01 00:00:00

  • High rates of police detention among recently released HIV-infected prisoners in Ukraine: implications for health outcomes.

    abstract：BACKGROUND:Ukraine's HIV epidemic, primarily affecting people who inject drugs (PWID), is expanding and transitioning despite free opioid substitution therapy (OST) and antiretroviral therapy (ART), two effective ways to reduce HIV transmission. Police detention of PWID not resulting in a formal charge or imprisonment ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2013.05.018

    authors： Izenberg JM,Bachireddy C,Soule M,Kiriazova T,Dvoryak S,Altice FL

    更新日期：2013-11-01 00:00:00

  • Brief intervention in general hospital for problematic prescription drug use: 12-month outcome.

    abstract：BACKGROUND:The problematic use of prescription drugs (PDs) and related disorders are considerably prevalent but evidence concerning brief intervention for problematic PD users is sparse. A previous analysis of the present study on the effectiveness of brief intervention for problematic PD use in a general hospital reve...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.drugalcdep.2009.07.010

    authors： Otto C,Crackau B,Löhrmann I,Zahradnik A,Bischof G,John U,Rumpf HJ

    更新日期：2009-12-01 00:00:00

  • Measuring pain medication expectancies in adults treated for substance use disorders.

    abstract：BACKGROUND:The U.S. prevalence of misuse of prescription opioid analgesics has increased substantially over the past decade but research on the factors influencing misuse of these medications remains preliminary. In the literature on alcohol, marijuana and stimulants, substance-related expectancies have been found to p...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2010.10.007

    authors： Ilgen MA,Roeder KM,Webster L,Mowbray OP,Perron BE,Chermack ST,Bohnert AS

    更新日期：2011-05-01 00:00:00

  • Prevalence and correlates of waterpipe tobacco smoking by college students in North Carolina.

    abstract：BACKGROUND:Known most commonly in the U.S. as "hookah," waterpipe tobacco smoking appears to be growing among college students. Despite beliefs that waterpipe use is safer than cigarette smoking, research to date (albeit limited) has found health risks of waterpipe smoking are similar to those associated with cigarette...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.drugalcdep.2011.01.018

    authors： Sutfin EL,McCoy TP,Reboussin BA,Wagoner KG,Spangler J,Wolfson M

    更新日期：2011-05-01 00:00:00

  • The iatrogenic epidemic of prescription drug abuse: county-level determinants of opioid availability and abuse.

    abstract：BACKGROUND:Opioid use and abuse in the United States continues to expand at an alarming rate. In this study, we examine the county-level determinants of the availability and abuse of prescription opioids to better understand the socio-ecological context, and in particular the role of the healthcare delivery system, on ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2014.03.002

    authors： Wright ER,Kooreman HE,Greene MS,Chambers RA,Banerjee A,Wilson J

    更新日期：2014-05-01 00:00:00

  • Reduced anterior prefrontal cortex activation in young binge drinkers during a visual working memory task.

    abstract：:Working memory (WM) is a major cognitive function that is altered by chronic alcohol consumption. This impairment has been linked to alterations in the hippocampus and prefrontal cortex (PFC). Animal and human studies have shown that the adolescent brain is more sensitive to the neurotoxic effects of alcohol than the ...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2009.11.020

    authors： Crego A,Rodriguez-Holguín S,Parada M,Mota N,Corral M,Cadaveira F

    更新日期：2010-06-01 00:00:00

  • Prevalence, timing, and predictors of transitions from inhalant use to inhalant use disorders.

    abstract：BACKGROUND:Few studies of the natural history of DSM-IV inhalant substance use disorders (I-SUDs) have been conducted. This investigation examined the prevalence, timing, and predictors of transitions from inhalant use to formal I-SUDs among inhalant users within a nationally representative sample. METHODS:Participant...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2008.10.017

    authors： Perron BE,Howard MO,Maitra S,Vaughn MG

    更新日期：2009-03-01 00:00:00

  • A placebo controlled clinical trial of buprenorphine as a treatment for opioid dependence.

    abstract：:Large-scale placebo controlled clinical trials assessing the efficacy of medications for the treatment of drug dependence have generally been limited to alcohol, cocaine and nicotine dependent populations. The purpose of the present study was to assess the early (1-2 week) clinical effectiveness of buprenorphine versu...

    journal_title：Drug and alcohol dependence

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0376-8716(95)01186-2

    authors： Johnson RE,Eissenberg T,Stitzer ML,Strain EC,Liebson IA,Bigelow GE

    更新日期：1995-11-01 00:00:00

  • The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002.

    abstract：BACKGROUND:Alcohol abuse and dependence can be disabling disorders, but accurate information is lacking on the prevalence of current DSM-IV alcohol abuse and dependence and how this has changed over the past decade. The purpose of this study was to present nationally representative data on the prevalence of 12-month DS...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2004.02.004

    authors： Grant BF,Dawson DA,Stinson FS,Chou SP,Dufour MC,Pickering RP

    更新日期：2004-06-11 00:00:00

  • Rapid cortical hemoglobin deoxygenation after heroin and methadone injection in humans: a preliminary report.

    abstract：:The short-term effects of intravenous opioids (heroin 20-300 mg, methadone 30-180 mg) on cortical hemoglobin oxygenation were examined by near infrared spectroscopy in ten opioid-dependent subjects and were compared with the effects of saline in ten age-matched normal controls. Heroin and methadone produced a rapid an...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/s0376-8716(99)00036-8

    authors： Stohler R,Dürsteler KM,Störmer R,Seifritz E,Hug I,Sattler-Mayr J,Muller-Spahn F,Ladewig D,Hock C

    更新日期：1999-11-01 00:00:00

  • Denial in methamphetamine users: Associations with cognition and functional connectivity in brain.

    abstract：BACKGROUND:Despite harmful consequences of drug addiction, it is common for individuals with substance use disorders to deny having problems with drugs. Emerging evidence suggests that some drug users lack insight into their behavior due to neurocognitive dysfunction, but little research has examined potential neurocog...

    journal_title：Drug and alcohol dependence

    pub_type： 杂志文章

    doi：10.1016/j.drugalcdep.2015.03.004

    authors： Dean AC,Kohno M,Morales AM,Ghahremani DG,London ED

    更新日期：2015-06-01 00:00:00