The iatrogenic epidemic of prescription drug abuse: county-level determinants of opioid availability and abuse.

abstract：:Cannabis sativa (marijuana plant) contains myriad cannabinoid compounds; yet, investigative attention has focused almost exclusively on Delta(9)-tetrahydrocannabinol (THC), its primary psychoactive substituent. Interest in modulation of THC's effects by these other cannabinoids (e.g., cannabidiol (CBD)) has been stimu...

journal_title：Drug and alcohol dependence

authors： Vann RE,Gamage TF,Warner JA,Marshall EM,Taylor NL,Martin BR,Wiley JL

更新日期：2008-04-01 00:00:00

abstract：:There has been a considerable increase in the number of intravenous amphetamine misusers during the last decade, and the development of effective treatment strategies for this high-risk group has become critical. The use of substitute prescribing is one option, but reservations have been expressed as to its demonstrat...

journal_title：Drug and alcohol dependence

authors： Charnaud B,Griffiths V

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND AIMS:A good therapeutic alliance plays a major role in the healing process. Professionals working in addiction treatment report high levels of psychological distress related to work and this may challenge the establishment of a trustful therapeutic alliance, and lead to a loss of care quality provided to...

journal_title：Drug and alcohol dependence

authors： Reyre A,Jeannin R,Largueche M,Moro MR,Baubet T,Taieb O

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Although both men and women use e-cigarettes, most preclinical nicotine research has focused on its effects in male rodents following injection. The goals of the present study were to develop an effective e-cigarette nicotine delivery system, to compare results to those obtained after subcutaneous (s.c.) inj...

journal_title：Drug and alcohol dependence

authors： Lefever TW,Lee YO,Kovach AL,Silinski MA,Marusich JA,Thomas BF,Wiley JL

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:In previous work we (Fisher et al., 2011) examined the emergence of neurobehavioral disinhibition (ND) in adolescents with prenatal substance exposure. We computed ND factor scores at three age points (8/9, 11 and 13/14 years) and found that both prenatal substance exposure and early adversity predicted ND. ...

journal_title：Drug and alcohol dependence

authors： Lester BM,Lin H,Degarmo DS,Fisher PA,Lagasse LL,Levine TP,Shankaran S,Bada HS,Bauer CR,Hammond JA,Whitaker TM,Higgins RD

更新日期：2012-11-01 00:00:00

abstract：:A methadone withdrawal programme (MWP) and a behaviour therapy programme (BTP) were compared in terms of their effectiveness to prevent relapse of heroin addicts after methadone treatment. The BTP incorporated systematic desensitization to effect a decrease in levels of fear of both physical and environmental withdraw...

journal_title：Drug and alcohol dependence

authors： Hollonds GB,Oei TP,Turecek LR

更新日期：1980-02-01 00:00:00

abstract：:Phospholipids are essential components of cell membranes which may also function to mediate some of the behavioural effects of dopamine receptor stimulation caused by psychostimulant drugs. Neuroimaging and pharmacological data suggest that abnormal brain metabolism of phospholipids might explain some of the consequen...

journal_title：Drug and alcohol dependence

authors： Ross BM,Moszczynska A,Peretti FJ,Adams V,Schmunk GA,Kalasinsky KS,Ang L,Mamalias N,Turenne SD,Kish SJ

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND/AIMS:We assessed to what extent adolescents use alcohol and cannabis simultaneously and expanded previous research by estimating the proportion of all events of cannabis use that had occurred in relation to drinking. How the prevalence of this form of polysubstance use co-varied with the overall level of alc...

journal_title：Drug and alcohol dependence

authors： Pape H,Rossow I,Storvoll EE

更新日期：2009-04-01 00:00:00

abstract：:Olfactory evoked potentials (OEP) were elicited by odorous and nonodorous stimuli in 50 adult subjects: 26 subjects with histories of either cocaine (n = 19) or alcohol (n = 7) dependence, 10 with histories of nicotine but no other drug dependence, 2 with clinical anosmia of peripheral origin, and 12 subjects without ...

journal_title：Drug and alcohol dependence

authors： Bauer LO,Mott AE

更新日期：1996-09-01 00:00:00

abstract：:Research on religion and alcohol has produced conclusive results with regard to the relationship between religion and alcohol consumption but ambiguous findings with regard to more general attitudes towards alcohol use. This paper considers these issues in depth by a secondary analysis of data collected in the Western...

journal_title：Drug and alcohol dependence

authors： Mullen K,Blaxter M,Dyer S

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Genetic influences on smoking cessation treatment outcome may be affected by pretreatment patient characteristics. Nicotine dependence is arguably the most salient clinical factor in smoking cessation. METHODS:In this secondary analysis of clinical trial data (N=793), we examined nicotine dependence severit...

journal_title：Drug and alcohol dependence

authors： Leventhal AM,Lee W,Bergen AW,Swan GE,Tyndale RF,Lerman C,Conti DV

更新日期：2014-05-01 00:00:00

abstract：RATIONALE:Two previous studies have utilized diffusion tensor imaging (DTI) to examine microstructural integrity in cocaine abuse and found evidence of brain abnormalities in white matter. OBJECTIVE:Using anatomical magnetic resonance imaging (MRI), DTI, and clinical evaluation, the macrostructural and microstructural...

journal_title：Drug and alcohol dependence

authors： Lim KO,Wozniak JR,Mueller BA,Franc DT,Specker SM,Rodriguez CP,Silverman AB,Rotrosen JP

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Group differences in brain structure between methamphetamine-dependent and healthy research participants have been reported, but findings in the literature present discrepancies. Although most methamphetamine-abusing individuals also smoke cigarettes, the effects of smoking on brain structure have not been d...

journal_title：Drug and alcohol dependence

authors： Morales AM,Lee B,Hellemann G,O'Neill J,London ED

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To examine lifetime and current prevalence rates of substance use disorders and the demographic and clinical correlates of current drug dependence in a sample of homeless women. METHODS:A cross-sectional study of 196 homeless women in three Canadian cities was done. Each subject was assessed using structured...

journal_title：Drug and alcohol dependence

authors： Torchalla I,Strehlau V,Li K,Krausz M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:We previously reported that when long-term abstinent alcoholics (LTAA; with no drug comorbidity) are compared to controls, they show increased resting state synchrony (RSS) in the executive control network and reduced RSS in the appetitive drive network suggestive of compensatory mechanisms that may facilita...

journal_title：Drug and alcohol dependence

authors： Camchong J,Stenger VA,Fein G

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Alcohol Use Disorder (AUD) is associated with problems with processing complex social scenarios. Little is known about the relationship between distinct AUD-related factors (e.g., years of problematic drinking), aspects of cognitive function and dysfunction in individuals diagnosed with AUD, and the relative...

journal_title：Drug and alcohol dependence

authors： Cox S,Bertoux M,Turner JJD,Moss A,Locker K,Riggs K

更新日期：2018-06-01 00:00:00

abstract：:Subjective and electroencephalographic reactions to cocaine cues were evaluated in 33 cocaine-dependent out-patients and 17 non-cocaine-dependent controls. Subjective, EEG, and autonomic reactions to three 5-min videos (cocaine-associated, erotic, neutral) were evaluated twice with an interpolated 1-week interval. Bet...

journal_title：Drug and alcohol dependence

authors： Hersh D,Bauer LO,Kranzler HR

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Addiction is associated with dorso-lateral prefrontal cortex (DLPFC) dysfunction and altered brain-oscillations. High frequency repetitive transcranial magnetic stimulation (HFrTMS) over DLPFC reportedly reduces drug craving. Its effects on neuropsychological, behavioural and neurophysiological are unclear. ...

journal_title：Drug and alcohol dependence

authors： Del Felice A,Bellamoli E,Formaggio E,Manganotti P,Masiero S,Cuoghi G,Rimondo C,Genetti B,Sperotto M,Corso F,Brunetto G,Bricolo F,Gomma M,Serpelloni G

更新日期：2016-01-01 00:00:00

abstract：:The purpose of the present investigation is to determine if various alcohol-related causes of death are associated with similar occupational groups. The California Occupational Mortality Study data set (1979-1981) provided information on primary occupation and deaths from cirrhosis, digestive cancers, injury, suicide ...

journal_title：Drug and alcohol dependence

authors： Brooks SD,Harford TC

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the factors associated with drinking behavior of cancer survivors after cancer diagnosis. METHODS:The study subjects were 906 adult cancer survivors who had reportedly drunk alcohol before cancer diagnosis and participated in the Korean National Health and Nutrition Examination ...

journal_title：Drug and alcohol dependence

authors： Ko H,Song YM,Shin JY

更新日期：2017-02-01 00:00:00

abstract：:The debate about cannabis policy in Australia has revolved around the harms that cannabis causes to users and the community, on the one hand, and the harms that are caused by the prohibition of its use, on the other. This paper assesses evidence on: (1) the harms caused to users and the community by cannabis use (deri...

journal_title：Drug and alcohol dependence

authors： Hall W

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Patients with prescription opioid use disorder commonly report relief of chronic pain as the chief reason for first opioid use; indeed, the prevalence of chronic pain is high in this population. Understanding the association between pain severity and subsequent opioid use is crucial for understanding how to ...

journal_title：Drug and alcohol dependence

authors： Griffin ML,McDermott KA,McHugh RK,Fitzmaurice GM,Jamison RN,Weiss RD

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:To evaluate whether cigarette smoking in Chinese urban areas was respectively associated with exposure to tobacco advertising and smoking bans in households, workplaces, and public places. METHODS:Participants were 4735 urban residents aged 15 years and older, who were identified through multi-stage quota-s...

journal_title：Drug and alcohol dependence

authors： Yang T,Rockett IR,Li M,Xu X,Gu Y

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Injection drug users (IDUs) are at high-risk for hepatitis B virus (HBV) and HIV. Due to concerns about non-adherence to multi-dose vaccine regimens however, IDUs are severely under-immunized against HBV and have been excluded from phase III trials of multi-dose candidate HIV vaccines in the United States. ...

journal_title：Drug and alcohol dependence

authors： Seal KH,Kral AH,Lorvick J,McNees A,Gee L,Edlin BR

更新日期：2003-08-20 00:00:00

abstract：BACKGROUND:Preclinical research has demonstrated a causal relationship between medial prefrontal cortex activity and cocaine self-administration. As a step towards translating those data to a neural circuit-based intervention for patients, this study sought to determine if continuous theta burst stimulation (cTBS) to t...

journal_title：Drug and alcohol dependence

authors： Hanlon CA,Dowdle LT,Correia B,Mithoefer O,Kearney-Ramos T,Lench D,Griffin M,Anton RF,George MS

更新日期：2017-09-01 00:00:00

abstract：:A single dose of ethanol has been shown to affect both striatal and hippocampal high-affinity choline uptake. This effect is probably mediated through effects of ethanol on acetylcholine release. Choline uptake has also been shown to be altered in ethanol-dependent animals, and these effects may be coupled to alterat...

journal_title：Drug and alcohol dependence

authors： Hunt WA,Majchrowicz E

更新日期：1979-05-01 00:00:00

abstract：:Cocaine-induced kindling, which has been hypothesized to underlie cocaine-induced craving, is reversed by carbamazepine treatment. Though preliminary studies showed carbamazepine to be useful for relapse prevention in cocaine-dependent subjects, more recent studies have failed to replicate those findings. We conducted...

journal_title：Drug and alcohol dependence

authors： Kranzler HR,Bauer LO,Hersh D,Klinghoffer V

更新日期：1995-06-01 00:00:00

abstract：:Social context may be an important determinant of drug and alcohol consumption and HIV-related behaviors. To assess the influence of peers on drug users' risk behaviors this study examined the association between individual level and group level behaviors. This analysis reports on the prospective association between b...

journal_title：Drug and alcohol dependence

authors： Latkin CA,Mandell W,Vlahov D

更新日期：1996-11-01 00:00:00

abstract：RATIONALE:There is evidence that serotonergic processes may modulate the processing of fearful facial expressions. It is therefore possible that the recreational drug 'ecstasy' (MDMA), which has marked serotonergic effects, may affect people's ability to recognise human facial expressions portraying fear. OBJECTIVE:Th...

journal_title：Drug and alcohol dependence

authors： Hoshi R,Bisla J,Curran HV

更新日期：2004-12-07 00:00:00

abstract：:To determine whether differences in life styles and patterns of drug use may help to account for willingness to try heroin and/or likelihood of becoming addicted, personal history interviews were conducted with 15 young heroin addict, 15 experimenters who used the drug but did not become addicts, and 15 nonusers who n...

journal_title：Drug and alcohol dependence

authors： Crawford GA

更新日期：1978-05-01 00:00:00