Chlorella virus PBCV-1 encodes a homolog of the bacteriophage T4 UV damage repair gene denV.

Abstract:

:The bacteriophage T4 denV gene encodes a well-characterized DNA repair enzyme involved in pyrimidine photodimer excision. We have discovered the first homologs of the denV gene in chlorella viruses, which are common in fresh water. This gene functions in vivo and also when cloned in Escherichia coli. Photodamaged virus DNA can also be photoreactivated by the host chlorella. Since the chlorella viruses are continually exposed to solar radiation in their native environments, two separate DNA repair systems, one that functions in the dark and one that functions in the light, significantly enhance their survival.

journal_name

Appl Environ Microbiol

authors

Furuta M,Schrader JO,Schrader HS,Kokjohn TA,Nyaga S,McCullough AK,Lloyd RS,Burbank DE,Landstein D,Lane L,Van Etten JL

doi

10.1128/AEM.63.4.1551-1556.1997

subject

Has Abstract

pub_date

1997-04-01 00:00:00

pages

1551-6

issue

4

eissn

0099-2240

issn

1098-5336

journal_volume

63

pub_type

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