Transient postnatal thyroxine treatment leads to an increased number of cholinergic neurons in the medial septum and to a higher density of cholinergic fibers in hippocampal CA3 in rats.

abstract：:Glia are key regulators of inflammatory responses within the central nervous system (CNS) following infection or trauma. We have previously demonstrated the ability of activated astrocytes to rapidly produce pro-inflammatory mediators followed by a transition to an anti-inflammatory cytokine production profile that in...

journal_title：Neuroscience letters

authors： Burmeister AR,Johnson MB,Marriott I

更新日期：2019-08-24 00:00:00

abstract：:The crossed thalamo-cortical and cortico-thalamic connections of the mouse are drawn using the tracer wheat germ agglutinin-horseradish peroxidase. After injections in the frontal cortex of the right hemisphere cells labeled retrogradely and axons labeled anterogradely are observed in the thalamus ipsilateral and cont...

journal_title：Neuroscience letters

authors： Carretta D,Sbriccoli A,Santarelli M,Pinto F,Granato A,Minciacchi D

更新日期：1996-02-02 00:00:00

abstract：:In this report the effects of phencyclidine (PCP) on physiologic variables, local cerebral blood flow (LCBF), and on hippocampal cell damage were measured in a rat model of forebrain ischemia (2-vessel occlusion and hypotension). Ischemia was induced for 10 min. LCBF was determined after 2 min of recirculation, using ...

journal_title：Neuroscience letters

authors： Sauer D,Nuglisch J,Rossberg C,Mennel HD,Beck T,Bielenberg GW,Krieglstein J

更新日期：1988-09-12 00:00:00

abstract：:Secretion of alpha-melanophore-stimulating hormone (alpha-MSH) from the neuroendocrine melanotrope cells in the intermediate lobe of the pituitary gland of the clawed frog Xenopus laevis is regulated by various inhibitory, stimulatory and autocrine factors. The neuropeptide sauvagine stimulates alpha-MSH secretion by ...

journal_title：Neuroscience letters

authors： van den Hurk MJ,Jenks BG,Roubos EW,Scheenen WJ

更新日期：2005-03-29 00:00:00

abstract：:Substance P immunoreactivity has been detected in varicosities around cell bodies of the nucleus dorsalis (Clarke's column) of the human spinal cord. This immunostaining probably represents neuropeptide immunoreactivity either in the nerve terminals of spinal interneurone, descending projections or in the primary dors...

journal_title：Neuroscience letters

authors： Pioro EP,Hughes JT,Cuello AC

更新日期：1984-09-28 00:00:00

abstract：:Precise evaluation of the ascending reticular activating system (ARAS) is important for diagnosis, prediction of prognosis, and management of patients with disorders of impaired consciousness. In the current study, we attempted to reconstruct the direct neural pathway between the brainstem reticular formation (RF) and...

journal_title：Neuroscience letters

authors： Jang SH,Kwon HG

更新日期：2015-10-08 00:00:00

abstract：:This study compared the immediate and prolonged effects of acute bouts of active and passive leg cycling on the soleus H-reflex among 12 young healthy men. The soleus H-reflex was measured immediately before and then 10 and 30 min after 20 min of active, unloaded leg cycling, passively induced leg cycling, and quiet r...

journal_title：Neuroscience letters

authors： Motl RW,Knowles BD,Dishman RK

更新日期：2003-08-21 00:00:00

abstract：:Unilateral intraplantar injections (1/day for 3 days) of 4 mu g nerve growth factor (NGF) into the rat hindpaw increased the expression of prepro-tachykinin (PPT)- and prepro-calcitonin gene-related peptide (ppCGRP)-mRNA in bilateral L5 dorsal root ganglia (DRGs). This was accompanied by an increase of CGRP-like immun...

journal_title：Neuroscience letters

authors： Amann R,Sirinathsinghji DJ,Donnerer J,Liebmann I,Schuligoi R

更新日期：1996-01-26 00:00:00

abstract：:Seizures and death are the more important toxic consequences related to cocaine overdose. Some reports have shown that pharmacological manipulations in dopaminergic, serotonergic and noradrenergic systems alter the occurrence of cocaine-induced convulsions and death. Based on this fact, this work was performed to dete...

journal_title：Neuroscience letters

authors： Macêdo DS,Vasconcelos SM,Belchior LD,Santos RS,Viana GS,Sousa FC

更新日期：2004-05-27 00:00:00

abstract：:c-Fos is one of the transcription factors contributing to the regulation of the downstream gene expression. Administration of dopamine D1 receptor agonist or D2 receptor antagonist have been known to induce c-Fos expressions in striatal projection neurons. We examined the effects of unilateral ablation of the globus p...

journal_title：Neuroscience letters

authors： Miwa H,Fuwa T,Nishi K,Mizuno Y

更新日期：1998-01-16 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) is a very important mitogenic factor with proved neurogenesis effects in the central nervous system. Intranasal administration can bypass blood-brain barrier and deliver drugs into the brain directly. We investigated whether intranasal administration of bFGF at later time points a...

journal_title：Neuroscience letters

authors： Wang ZL,Cheng SM,Ma MM,Ma YP,Yang JP,Xu GL,Liu XF

更新日期：2008-11-28 00:00:00

abstract：:Two types of mRNAs for neurofibromin isoforms, which are produced by Von Recklinghausen neurofibromatosis (NF1) gene, have so far been identified. In the present study, we analyzed the differential expression of the two NF1 mRNAs in 16 cases of human astrocytic tumors and in surrounding normal tissues by the RNA-polym...

journal_title：Neuroscience letters

authors： Tokuyama T,Uemura K,Fujita M

更新日期：1995-08-25 00:00:00

abstract：:Tobacco smoke inhibits monoamine oxidase-B (MAO-B) activity in vitro and in vivo, suggesting that MAO-B inhibition is a possible contributing factor to tobacco smoke addiction. Thus, MAO-B is a possible candidate gene for predisposition to smoking. The TaqIB polymorphism for the Dopamine D2 Receptor gene (DRD2) has be...

journal_title：Neuroscience letters

authors： Costa-Mallen P,Costa LG,Checkoway H

更新日期：2005-09-09 00:00:00

abstract：:The actions of vasoactive intestinal polypeptide (VIP) were investigated on superficial dorsal horn (LI-IV) neurones in longitudinal slices of the rat lumbar spinal cord in vitro. Bath application of VIP (1-2 mM) cause depolarizations which were accompanied by a lowering of the threshold for excitation of the neurone ...

journal_title：Neuroscience letters

authors： Liu XH,Morris R

更新日期：1999-11-26 00:00:00

abstract：:Effects of cortisol on 22 tuberoinfundibular (TI) neurons in the paraventricular nucleus (PVN) of the hypothalamus were examined in urethane-anesthetized rats. Iontophoretically applied cortisol excited 10 (45%) of 22 TI-neurons tested, whereas the cortisol inhibited 4 (31%) of 13 neurons in the periventricular hypoth...

journal_title：Neuroscience letters

authors： Kasai M,Kannan H,Ueta Y,Osaka T,Inenaga K,Yamashita H

更新日期：1988-04-22 00:00:00

abstract：:Conduction velocities of antidromically evoked impulses along the goldfish Mauthner axon were found to be inversely correlated with body length. To test the hypothesis that such a relation is accompanied by a reduction in axonal diameter with increasing fish size, Mauthner axon diameters were measured. A parabolic rel...

journal_title：Neuroscience letters

authors： Funch PG,Kinsman SL,Faber DS,Koenig E,Zottoli SJ

更新日期：1981-12-11 00:00:00

abstract：:The effect of different frequencies of music on brain function was investigated through measurement of blood pressure in spontaneously hypertensive rats (SHR). Previous studies indicated that exposure to Mozart's music (K. 205) leads to increased calcium/calmodulin-dependent dopamine synthesis in the brain, and that t...

journal_title：Neuroscience letters

authors： Akiyama K,Sutoo D

更新日期：2011-01-03 00:00:00

abstract：:The combination of ethanol and cocaine is commonly abused by human addicts which has serious clinical consequences. Here, the effects of separately and concurrently administered ethanol and 'binge' cocaine on kappa opioid receptor (KOR) mRNA in the ventral tegmental area (VTA) and nucleus accumbens (NAc) of rats were ...

journal_title：Neuroscience letters

authors： Rosin A,Lindholm S,Franck J,Georgieva J

更新日期：1999-11-05 00:00:00

abstract：:The IKK/NF-κB signalling pathway plays a predominant role in the regulation of inflammation and apoptosis in spinal cord injury (SCI). We have previously demonstrated that targeting of the IKK/NF-κB pathway improved the recovery of locomotor function by reducing the infiltration of inflammatory cells and apoptosis aft...

journal_title：Neuroscience letters

authors： Lu M,Wang S,Han X,Lv D

更新日期：2013-05-10 00:00:00

abstract：:The diagonal band of Broca (DBB) is involved in cardiovascular control in rats. In the present study, we report the effect of acute and reversible neurotransmission inhibition in the DBB by bilateral microinjection of the nonselective neurotransmission blocker CoCl(2) (1mM, 100 nL) on the cardiac baroreflex response i...

journal_title：Neuroscience letters

authors： Crestani CC,Tavares RF,Alves FH,Resstel LB,Corrêa FM

更新日期：2008-12-26 00:00:00

abstract：:This study investigates whether potassium ion (K+) channels are involved in the nitric oxide (NO)-induced relaxation in segments of the isolated rat basilar artery, mounted onto a wire myograph. A high extracellular K+ concentration partly inhibited the relaxant effects of the NO donors DEA/NO and SIN-1 (3-morpholino-...

journal_title：Neuroscience letters

authors： Hempelmann RG,Seebeck J,Kruse ML,Ziegler A,Mehdorn HM

更新日期：2001-11-02 00:00:00

abstract：:Employing double anterograde axonal tracing in combination with intracortical microstimulation, we examined the distribution patterns of corticosubthalamic inputs from forelimb representations of the dorsal (PMd) and ventral (PMv) divisions of the premotor cortex in the macaque monkey. The inputs from the PMd and PMv ...

journal_title：Neuroscience letters

authors： Nambu A,Tokuno H,Inase M,Takada M

更新日期：1997-12-12 00:00:00

abstract：:Previous studies have shown that striatum and nucleus accumbens (NAc) are two different structures in mediating addictive drug-induced ascorbic acid (AA) release. In order to further characterize the different effects of drugs-induced AA release in the striatum and NAc, in the present study, we investigated the effect...

journal_title：Neuroscience letters

authors： Gu PF,Wu CF,Yang JY,Shang Y,Hou Y,Bi XL,Dai F

更新日期：2006-05-15 00:00:00

abstract：:In vitro studies suggest that insulin-like growth factor (IGF)-I is a mitogen for microglia/macrophages. The actions of IGF-I are mediated by IGF-I receptors and modulated by IGF binding proteins (IGFBPs). The aim of this study was to investigate IGF-I receptors and IGFBPs in human microglia in normal brain white matt...

journal_title：Neuroscience letters

authors： Chesik D,De Keyser J,Wilczak N

更新日期：2004-05-13 00:00:00

abstract：:IL-1beta is a proinflammatory cytokine that contributes to psychological stress responses and has been implicated in various psychiatric disorders most notably depression. Preclinical studies also demonstrate that IL-1beta modulates anxiety- and fear-related behaviors, although these findings are difficult to assess b...

journal_title：Neuroscience letters

authors： Koo JW,Duman RS

更新日期：2009-05-29 00:00:00

abstract：:Acute and chronic damage to the central nervous system (CNS) releases large quantities of ATP. Whereas the ATP concentration in the extracellular space is normally in the micromolar range, under these conditions it increases to millimolar levels. A number of ligand-gated cationic channels termed P2X receptors (7 mamma...

journal_title：Neuroscience letters

authors： Franke H,Illes P

更新日期：2014-04-17 00:00:00

abstract：:Recent studies have shown that aging, psychiatric and neurologic diseases, and dopaminergic blockade all result in altered brain network efficiency. We investigated the efficiency of human brain functional networks as measured by fMRI in individuals with idiopathic Parkinson's disease (N=14) compared to healthy age-ma...

journal_title：Neuroscience letters

authors： Skidmore F,Korenkevych D,Liu Y,He G,Bullmore E,Pardalos PM

更新日期：2011-07-15 00:00:00

abstract：:Dopamine D1 and D2 receptors were studied in putamen of post-mortem brains from controls and patients with Alzheimer-type dementia (ATD). A significant reduction in dopamine D2 receptors was observed in ATD, whereas dopamine D1 receptors were unchanged. Neurochemical markers of striatal acetylcholine and GABA-containi...

journal_title：Neuroscience letters

authors： Cross AJ,Crow TJ,Ferrier IN,Johnson JA,Markakis D

更新日期：1984-11-23 00:00:00

abstract：:Five monkeys vocalizing at self-pace (self-paced vocalization) were well trained to vocalize in response to a monkey call (audio-initiated vocalization). Field potentials associated with audio-initiated vocalizations were recorded by using electrodes which were implanted chronically on the surface and at a 2.0-3.0 mm ...

journal_title：Neuroscience letters

authors： Gemba H,Kyuhou S,Matsuzaki R,Amino Y

更新日期：1999-09-03 00:00:00

abstract：:A predominant form of the GABAA/benzodiazepine receptor-Cl- channel complex is believed to consist of three different 48-55 kDa subunits (alpha, beta, gamma) with unknown stoichiometry. Plasmids containing the rat GABAA receptor cDNAs coding for alpha 1, beta 2, and gamma 2 were co-transfected, along with a plasmid en...

journal_title：Neuroscience letters

authors： Hamilton BJ,Lennon DJ,Im HK,Im WB,Seeburg PH,Carter DB

更新日期：1993-04-30 00:00:00