Co-agglutination (Co-A) test for circulating antigen in hydatid disease.

Abstract:

:A co-agglutination (Co-A) test with Staphylococcus aureus (Cowan's strain I) bearing protein A coated with specific hydatid antibodies, was used to demonstrate circulating hydatid antigen in serum for the diagnosis of hydatid disease. The test had a sensitivity of 95% and specificity of 89% in detecting hydatid antigen in serum. A false positive reaction was observed with 18.5% of control sera from patients with various parasitic diseases. However, these all gave negative results when tested after further dilution. The test is reliable and rapid; the result could be obtained within 30-45 min of receipt of a serum sample. Since the test is simple and the reagents are inexpensive and easily available, it can be used in less well equipped laboratories in developing countries.

journal_name

J Med Microbiol

authors

Shariff M,Parija SC

doi

10.1099/00222615-38-6-391

subject

Has Abstract

pub_date

1993-06-01 00:00:00

pages

391-4

issue

6

eissn

0022-2615

issn

1473-5644

journal_volume

38

pub_type

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