Lack of immunization after intraperitoneal insemination of spermatozoa.

Abstract:

:Twenty infertile patients with normal tubal patency were inseminated intraperitoneally (11 once, seven twice, and two three times) with spermatozoa (mean 14 x 10(6), range 0.6-48 x 10(6)) prepared by the standard swim-up technique. The occurrence of immunization to spermatozoa was looked for by the Gelatin Agglutination Test (GAT) and Tray Agglutination Test (TAT). Both tests gave negative results for all the controls (10 pregnant and 10 puerperal women). Antisperm antibodies were measured in the serum before, 30 d and 4-7 months after Intraperitoneal Insemination (IPI). The last check was done for only 14 patients, since six became pregnant as a consequence of the first treatment. Of the 14 patients studied after 4-7 months, seven had two, and two had three IPI. In the group of inseminated patients, 18 women with no basal sperm antibody did not show evidence of antibody formation after the treatment and it was not increased after insemination in the two patients who already had low antibody titre (1/32). In conclusion, despite the large number of spermatozoa inseminated and even after several IPI attempts, there was no evidence of de novo production of or increase in already present anti-sperm antibodies according to the methods used for the detection of ASA in this study.

journal_name

Andrologia

journal_title

Andrologia

authors

Ragni G,Lenzi A,Gandini L,Cristiani C,Lombroso GC,Olivares MD,Wyssling H,Dondero F,Crosignani PG

doi

10.1111/j.1439-0272.1993.tb02673.x

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

3-5

issue

1

eissn

0303-4569

issn

1439-0272

journal_volume

25

pub_type

杂志文章
  • Three cases of low chiasma frequency associated with infertility in man.

    abstract::Three new cases of low chiasma frequency in infertile men are described. In the first case, all cells showed abnormal diakineses; in the second, 20% of the diakineses were desynaptic, while the remaining 80% were normal; in the third, all diakineses were desynaptic and showed chromosome fragmentation. The possible mec...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1976.tb01657.x

    authors: Templado C,Marina S,Egozcue J

    更新日期:1976-01-01 00:00:00

  • A rare cause of recurrent priapism: hereditary angioedema.

    abstract::Hereditary angioedema is a rare disease, which is caused by deficiency of compleman c1 esterase inhibitor regulatory protein in the compleman system. Priapism is involuntary, painful and prolonged erection of penis more than 4 h without sexual desire. In this case report, we elucidated a patient diagnosed with heredit...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12297

    authors: Akyuz M,Kaya C,Akdogan MF

    更新日期:2015-06-01 00:00:00

  • Comparative study of functional and biochemical parameters in frozen bovine sperm.

    abstract::In order to correlate functional and biochemical parameters, frozen bovine sperm samples presenting diverse motility were studied. Specimens collected from four bulls (A, B, C and D) were graded according to motile spermatozoa percentage and vigour, regarding the sample from bull A as highest motility, those from bull...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1997.tb03146.x

    authors: Beorlegui N,Cetica P,Trinchero G,Córdoba M,Beconi M

    更新日期:1997-01-01 00:00:00

  • Deregulation of Aurora kinase gene expression in human testicular germ cell tumours.

    abstract::The Aurora kinases regulate chromosome segregation and cytokinesis, and alterations in their expression associate with cell malignant transformation. In this study, we demonstrated by qRT-PCR analysis of 14 seminomas that Aurora-A mRNA was, with respect to control tissues, augmented in five of 14 tumour tissues by 2.1...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2009.00987.x

    authors: Baldini E,Arlot-Bonnemains Y,Mottolese M,Sentinelli S,Antoniani B,Sorrenti S,Salducci M,Comini E,Ulisse S,D'Armiento M

    更新日期:2010-08-01 00:00:00

  • Mobility shift assay of calcium-binding proteins of mouse epididymal spermatozoa.

    abstract::The calcium-binding proteins (CBPs) of mouse epididymal spermatozoa were analysed by mobility changes in the presence of added Ca2+ in two-dimensional sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The expression patterns of relatively high molecular weight CBPs (Mr > 20 kDa) were different bet...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1046/j.1439-0272.2001.00419.x

    authors: Gye MC,Park S,Kim YS,Ahn HS

    更新日期:2001-07-01 00:00:00

  • Leydig cell function and morphology in the rat testis after exposure to heat.

    abstract::Leydig cell function, as judged from testosterone concentrations in plasma and in testicular tissue after LH stimulation, was tested in adult rat testes 4 days after brief exposure of the scrotum to 33 degrees and 43 degrees C, respectively. There was no significant difference in basal plasma testosterone concentratio...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1980.tb00568.x

    authors: Damber JE,Bergh A,Janson PO

    更新日期:1980-01-01 00:00:00

  • The presence of progressive motility sustaining factor (PMSF) in human epididymis.

    abstract::Progressive Motility Sustaining Factor (PMSF) was isolated from human epididymides. PMSF could significantly improve progressive motility of oligozoospermic as well as asthenozoospermic semen. PMSF was found to increase cyclic AMP accumulation by the human spermatozoa indicating its possible mode of action. ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1981.tb00021.x

    authors: Sheth AR,Gunjikar AN,Shah GV

    更新日期:1981-03-01 00:00:00

  • Decreased polyunsaturated and increased saturated fatty acid concentration in spermatozoa from asthenozoospermic males as compared with normozoospermic males.

    abstract::The lipid composition of the sperm membrane has been shown to exert a significant effect upon the functional quality of spermatozoa. We have studied fatty acid composition of the phospholipids in spermatozoa in asthenozoospermic and normozoospermic men and determined the ratio of polyunsaturated fatty acids (PUFAs) to...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2006.00735.x

    authors: Tavilani H,Doosti M,Abdi K,Vaisiraygani A,Joshaghani HR

    更新日期:2006-10-01 00:00:00

  • Two esterases common to seminal plasma, other external secretions and leucocytes in man.

    abstract::Two esterases previously identified in seminal plasma, on the basis of their electrophoretic mobility, immunogenicity and sensitivity to organophosphorus esters were detected in various human external secretions and leucocyte extracts. alpha-Esterase was found to be abundant in urine and milk whereas this enzyme occur...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1976.tb01650.x

    authors: Roberts TK,Masson PL,Lauwerys R,Heremans JF

    更新日期:1976-01-01 00:00:00

  • Contribution of epididymal factors to sperm maturation and storage.

    abstract::In fertile men, the majority of epididymal spermatozoa acquire the potential to fertilize (assessed with sperm function assays) on passage into the corpus and cauda regions of the epididymis. Although secretions of the epididymal epithelium are clearly important for sperm maturation and survival, their role in this pr...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0272.1998.tb01165.x

    authors: Moore HD

    更新日期:1998-08-01 00:00:00

  • Carnitine in seminal fluid as parameter for the epididymal function.

    abstract::Carnitine represents the secretion which is added to human seminal fluid by the epididymis. More than 94% of the free carnitine originates from the epididymis. The frequency distribution of carnitine concentration is investigated with patients showing a normal spermiogram and with those suffering from azoospermia. Cor...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1978.tb03017.x

    authors: Wetterauer U,Heite HJ

    更新日期:1978-05-01 00:00:00

  • Maternal and infant characteristics influencing the anogenital distance and penile length in newborns.

    abstract::Recent studies have suggested that maternal characteristics can affect reproductive health of offspring, possibly through pre-natal hormonal influence. Anogenital distance (AGD) is an anthropometric measure which is a sensitive reproductive endpoint of masculinisation. It provides a read-out of pre-natal androgen expo...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12507

    authors: Singal AK,Jain VG

    更新日期:2016-08-01 00:00:00

  • Evaluation of pubertal onset and characteristics in Egyptian boys: A cross-sectional study.

    abstract::The objective of this study was to evaluate pubertal onset and characteristics in Egyptian boys. Examination of schoolboys (9-18 years) included height (cm), penile length (cm) and testicular volume (ml). Pubertal onset was considered at gonadal (G) stage 2 (G2 indicated testicular volume from 4-8 ml). Out of 1,078 bo...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13192

    authors: Saleh R,Abu El-Hamd M,Abdel-Karim M,Abdelrahman H

    更新日期:2019-03-01 00:00:00

  • The Fas system in the seminiferous epithelium and its possible extra-testicular role.

    abstract::The Fas system is involved in the control of immune system homeostasis and nonfunctional Fas system leads to autoimmune disease in mice and humans. The Fas system is a mechanism through which cells expressing Fas ligand (FasL) induce apoptosis of Fas expressing cells. In mouse and rat, the testis represents the main s...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1046/j.1439-0272.2003.00538.x

    authors: Riccioli A,Salvati L,D'Alessio A,Starace D,Giampietri C,De Cesaris P,Filippini A,Ziparo E

    更新日期:2003-02-01 00:00:00

  • Treatment of infertile patients by intrauterine insemination of washed spermatozoa.

    abstract::Thirty-five couples with a variety of infertility problems were treated by a sperm-washing and intrauterine-insemination method. The husband's semen was washed with a modified Biggers, Whitten, and Whittingham's medium to obtain a seminal plasma-free, highly concentrated sperm suspension for intrauterine insemination....

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1985.tb00955.x

    authors: Wiltbank MC,Kosasa S,Rogers B

    更新日期:1985-01-01 00:00:00

  • Variations in elemental distribution in human spermatozoa.

    abstract::Morphologically normal spermatozoa from groups of men attending the infertility clinic with normal density and motility had subcellular elemental composition measurements from various parts of the spermatozoa compared with anatomically similar spermatozoa from semen with marked oligo- or asthenozoospermia. In the two ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1988.tb01060.x

    authors: Sheppard BL,Harrison RF,Sheppard U,Jordan M,Hannon K

    更新日期:1988-05-01 00:00:00

  • Outcome of microsurgical testicular sperm extraction in familial idiopathic nonobstructive azoospermia.

    abstract::The aim of the study was to evaluate the sperm retrieval rate by microsurgical testicular sperm extraction (TESE) in familial idiopathic nonobstructive azoospermia (NOA). One hundred and nineteen patients with idiopathic NOA who underwent microsurgical TESE over the past 5 years were included. Patients were then divid...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12378

    authors: Arafa MM,ElBardisi HT,AlSaid SS,Majzoub A,AlMalki AH,ElRobi I,AlAnsari AA

    更新日期:2015-11-01 00:00:00

  • Glutathione S-transferase M1 and T1 polymorphisms in Turkish patients with varicocele.

    abstract::Several studies have shown that high oxidative stress levels are associated with varicocele. The GST (glutathione S-transferase) family of genes is critical in the protection of cells from oxidative stress because they utilise as substrates a wide variety of products of oxidative stress. The objective of this study wa...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2010.01103.x

    authors: Acar H,Kılınç M,Guven S,Inan Z

    更新日期:2012-02-01 00:00:00

  • Testicular sperm extraction after laparoscopic orchiectomy for bilateral postpubertal intra-abdominal cryptorchidism: What chance of sperm retrieval?

    abstract::Infertility occurs in up to 54% of men with bilateral undescended testes. Orchiectomy is considered the best therapeutic approach, especially when cryptorchidism is diagnosed in adulthood, due to a high risk of malignancy. A 33-year-old man was referred with a clinical presentation of empty scrotum and an ultrasonogra...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12936

    authors: Cito G,Della Camera PA,Degli Innocenti S,Coccia ME,Nesi G,Cocci A,Morselli S,Minervini A,Carini M,Serni M,Gacci M,Natali A

    更新日期:2018-03-01 00:00:00

  • Soluble Fibrinogen-like protein 2 plays a role in varicocele induced male infertility.

    abstract::Varicocele is the most common cause of male infertility. Several theories have been proposed to explain how varicocele induces infertility. The role of epididymis in male infertility is not fully well established. Fibrinogen-like protein 2 is one of serine proteases and is a potent coagulant in membranous form and imm...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13626

    authors: Elesawy FM,Abdel Hafeez NA,Abdelsalam OH,Akl EM

    更新日期:2020-07-01 00:00:00

  • Blueberries prevent the effect of intermittent hypobaric hypoxia in rat epididymis.

    abstract::Intermittent hypobaric hypoxia (IHH) induced a decrease in sperm count and oxidative damage in epididymis. We have previously demonstrated that a blueberry-enriched polyphenol extract (BB-4) reduced the adverse effects of oxidative stress in rat testis under hypobaric hypoxia. The aim of this study was to evaluate whe...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12146

    authors: Zepeda AB,Calaf GM,Figueroa CA,Farías JG

    更新日期:2014-09-01 00:00:00

  • Meningiomas in three male-to-female transgender subjects using oestrogens/progestogens and review of the literature.

    abstract::Sex hormones have been proposed as a possible risk factor for the development and growth of meningiomas. Hormonal therapy plays a fundamental role in the treatment of male-to-female transgenders and needs to be continued after sex reassignment surgery. Usually, this treatment leads to no adverse events; however, its i...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.12550

    authors: Ter Wengel PV,Martin E,Gooren L,Den Heijer M,Peerdeman SM

    更新日期:2016-12-01 00:00:00

  • A rare karyotype of nonmosaic isodicentric (Y) (p11.31) with azoospermia and short stature.

    abstract::Chromosome aberration is one of the common causes of male infertility. Isodicentric chromosome is a chromosomal aberration in which two arms of a chromosome are identical in morphology and genetics and connected by two centromeres. We firstly reported a case of infertile male with nonmosaic 46, X, idic (Y) (qter-p11.3...

    journal_title:Andrologia

    pub_type:

    doi:10.1111/and.13536

    authors: Dai Y,Li H,Zhang X,Jia M,Gu X

    更新日期:2020-05-01 00:00:00

  • Serum sperm antibodies after diarrhoeal diseases.

    abstract::The origin of 'natural' anti-sperm antibodies found in fertile humans, virgin girls, and boys before puberty, is quite obscure. One hypothetical mechanism relates their existence to inflammatory gastrointestinal entities: as a result of the disease, cross-reactive antibodies produced against gastrointestinal flora bin...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2007.00772.x

    authors: Kalaydjiev S,Dimitrova D,Mitov I,Dikov I,Nakov L

    更新日期:2007-06-01 00:00:00

  • Effect of flutamide on the physiological status of epididymis and epididymal sperms.

    abstract::Flutamide, a pure antiandrogen, increases the levels of plasma luteinizing hormone but antagonizes the biological expression of androgen on target organs. Flutamide was administered to rats to study the effect of altered availability of hormones on the functional status of epididymis. The weights of ventral prostate, ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1992.tb02620.x

    authors: Mukherjee M,Chattopadhyay S,Mathur PP

    更新日期:1992-03-01 00:00:00

  • Icariin improves SHR erectile function via inhibiting eNOS uncoupling.

    abstract::The aim of the study was to investigate whether or not the effect of icariin on erectile function of SHR is associated with inhibition of eNOS uncoupling. Ten 12-week-old male WKY rats and 10 age-matched male SHR were evenly randomised into SHR control group, SHR+ icariin treatment group, WKY control group and WKY+ ic...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13084

    authors: Long H,Jiang J,Xia J,Jiang R

    更新日期:2018-11-01 00:00:00

  • Effects of a DNA-specific fluorochrome, Hoechst 33258, on mouse sperm motility and fertilizing capacity.

    abstract::DNA specific fluorochrome (Hoechst 33342 and 33258) as non-toxic stains, have been widely used to measure cell density and proliferation, detect sperm-egg fusion, and observe the development of pre-implantation embryos. It has been reported that Hoechst 33342 at a concentration of 10 micrograms ml-1 had significant in...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1992.tb02632.x

    authors: Yelian FD,Dukelow WR

    更新日期:1992-05-01 00:00:00

  • An experimental study: quantitatively evaluating the change of the content of collagen fibres in penis with two-dimensional ShearWave™ Elastography.

    abstract::The purpose of this study was to explore the value of two-dimensional ShearWave™ Elastography (2D-SWE) on quantitatively evaluating the change of the content of collagen fibres in penis. Twenty male Sprague Dawley rats were divided into the pre-sexual maturity group (Group 1) and the sexual decline group (Group 2) acc...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12653

    authors: Qiao XH,Zhang JJ,Gao F,Li F,Bai M,Du LF,Xing JF

    更新日期:2017-06-01 00:00:00

  • Polyorchidism with varicocele: a case report and review of literature.

    abstract::Polyorchidism is defined as the presence of more than 2 histologically proven testes. We report the case of a 20-year-old man with polyorchidism, presenting with right scrotal pain and right scrotal ovoid mass. Scrotal examination revealed two ovoid, mobile lumps with testicular sensation in the right side of the scro...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0272.2011.01205.x

    authors: Topsakal K,Ak H,Yumurtas N

    更新日期:2012-05-01 00:00:00

  • A snapshot of intralesional verapamil injection in the treatment of Peyronie's disease today.

    abstract::Studies assessing the efficacy of intralesional verapamil injection in the treatment of Peyronie's disease have yielded mixed results. The purpose of this meta-analysis is to systematise the existing literature on the efficacy of intralesional verapamil injection when used in the treatment of Peyronie's disease. The t...

    journal_title:Andrologia

    pub_type: 杂志文章,meta分析

    doi:10.1111/and.13388

    authors: Sadagopan A

    更新日期:2019-11-01 00:00:00